Index - Sciencemission

Science Hangouts

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

Science Hangouts

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

653

Modeling neurodevelomental disorders with stem cells and brain organoids

Science Hangouts

Modeling neurodevelomental disorders with stem cells and brain organoids

34

Zika virus and maternal fetal transmission

Science Hangouts

Zika virus and maternal fetal transmission

33

Assembling and disassembling the nervous system

Science Hangouts

Assembling and disassembling the nervous system

36

Science News Highlights

Hydrogen sulfide generation extends lifespan and healthspan

News highlights

Hydrogen sulfide generation extends lifespan and healthspan

1

The identity and function of dark microglia

News highlights

The identity and function of dark microglia

7

Proteostasis in the lifespan of hematopoietic stem cells

News highlights

Proteostasis in the lifespan of hematopoietic stem cells

5

News

Repairing damaged lysosomal membrane

Repairing damaged lysosomal membrane

13

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

11

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

33

Origin cells for malignant brain tumor identified

Origin cells for malignant brain tumor identified

26

A high-protein diet can defeat cholera infection

A high-protein diet can defeat cholera infection

25

Regulating protein production

Regulating protein production

31

Neural circuitry in bone and key signals for bone repair

Neural circuitry in bone and key signals for bone ...

21

High-fat diets make liver cells more likely to become cancerous

High-fat diets make liver cells more likely to bec...

110

How the brain creates facial expressions

How the brain creates facial expressions

24

How cells eliminate inefficient ribosomes

How cells eliminate inefficient ribosomes

7

Homer1 gene improves focus!

Homer1 gene improves focus!

24

Redox and pH changes shuts down AQP3 channel

Redox and pH changes shuts down AQP3 channel

46

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

11

Neural circuitry in bone and key signals for bone repair

Neural circuitry in bone and key signals for bone ...

21

How the brain creates facial expressions

How the brain creates facial expressions

24

Homer1 gene improves focus!

Homer1 gene improves focus!

24

Regulating tryptophan catabolism to control neurodegeneration

Regulating tryptophan catabolism to control neurod...

80

How stroke risk gene maintains brain small blood vessel function

How stroke risk gene maintains brain small blood v...

24

Stimulant ADHD medications work differently than thought

Stimulant ADHD medications work differently than t...

413

Alzheimer’s disease reversal by restoring the brain’s energy balance

Alzheimer’s disease reversal by restoring the brai...

72

Exercise enhances hormone shuttling across blood brain barrier

Exercise enhances hormone shuttling across blood b...

103

How energy, immune and vascular changes linked to ME/CFS

How energy, immune and vascular changes linked to ...

99

How the brain measures distance

How the brain measures distance

31

Distal enhancers controlling genes dysregulated in Alzheimer’s disease

Distal enhancers controlling genes dysregulated in...

55

How astrocytes stabilize neural circuits in adult brain

How astrocytes stabilize neural circuits in adult ...

47

Phosphorylation of tau inhibits HSV-1 infection

Phosphorylation of tau inhibits HSV-1 infection

62

Origin cells for malignant brain tumor identified

Origin cells for malignant brain tumor identified

26

High-fat diets make liver cells more likely to become cancerous

High-fat diets make liver cells more likely to bec...

110

Opposing functions of distinct regulatory T cell subsets in colorectal cancer

Opposing functions of distinct regulatory T cell s...

35

How glioblastoma tumors dodge chemotherapy

How glioblastoma tumors dodge chemotherapy

34

Targeting B cells enhances STING agonism in liver cancer

Targeting B cells enhances STING agonism in liver ...

50

How cancer escapes cell death and cell division arrest

How cancer escapes cell death and cell division ar...

45

How cancer cells survive immune attack

How cancer cells survive immune attack

97

Role of mobile DNA elements in lung cancer progression

Role of mobile DNA elements in lung cancer progres...

45

How microtubules take part in cellular signal processing

How microtubules take part in cellular signal proc...

74

Key driver of treatment-resistant cancer uncovered!

Key driver of treatment-resistant cancer uncovered!

75

Regulation of cellular aging!

Regulation of cellular aging!

85

How tumors thrive in acidic, low-oxygen environments?

How tumors thrive in acidic, low-oxygen environments?

90

Identifying suppressors of colorectal cancer metastasis

Identifying suppressors of colorectal cancer metas...

51

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

23

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

136

How the Immune System Stalls Weight Loss

How the Immune System Stalls Weight Loss

123

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

276

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

133

Mitochondrial ketone body oxidation impaired in diabetes & liver disease

Mitochondrial ketone body oxidation impaired in di...

103

Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

Sons of mothers with type 1 diabetes show early si...

61

Aged blood vessel cells drive metabolic diseases

Aged blood vessel cells drive metabolic diseases

104

Genes associated with obesity shared across ancestries

Genes associated with obesity shared across ancest...

92

A muscle specific protein reduces high ketone levels in diabetic patients

A muscle specific protein reduces high ketone leve...

78

Genetic variants controlling body weight

Genetic variants controlling body weight

111

Role of nuclear hormone-sensitive lipase (HSL) in lipid metabolism

Role of nuclear hormone-sensitive lipase (HSL) in ...

96

Glycation-lowering compounds curb hunger, lower insulin resistance and extend lifespan

Glycation-lowering compounds curb hunger, lower in...

237

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

25

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

27

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

53

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

95

AI-based software maps proteins and lipids within cells

AI-based software maps proteins and lipids within ...

74

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

89

AI model to detect skin cancer

AI model to detect skin cancer

65

AI Uncovers Genetic Architecture of the Human Corpus Callosum

AI Uncovers Genetic Architecture of the Human Corp...

114

AI can speed antibody design

AI can speed antibody design

108

AI generative models reveal the cortical representation of dancing

AI generative models reveal the cortical represent...

68

AI based biophysical models of neural dynamics

AI based biophysical models of neural dynamics

80

Human Replication Protein A complex is Essential for Telomere Maintenance

Human Replication Protein A complex is Essential f...

64

Amino acids play a key role in brain's G protein signaling

Amino acids play a key role in brain's G protein ...

119

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

86

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

65

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

90

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

125

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

94

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

128

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

156

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

125

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

308

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

282

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

386

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

518

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

375

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

33

How cell walls guide stem cells

How cell walls guide stem cells

24

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

49

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

42

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

57

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

39

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

27

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

69

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

160

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

49

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

72

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

69

How hair stem cells under stress make decisions to graying or melanoma

How hair stem cells under stress make decisions to...

87

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

11

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

11

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

60

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

40

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

46

Gene linked with risk of delirium

Gene linked with risk of delirium

42

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

77

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

67

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

93

A genome-to-proteome map

A genome-to-proteome map

106

Why naked mole-rats live longer

Why naked mole-rats live longer

71

Gene therapy for alpha thalassemia major

Gene therapy for alpha thalassemia major

115

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

135

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

39

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

43

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

89

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

377

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

398

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

371

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

386

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

266

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

354

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

394

Role of ECM in brain memory

Role of ECM in brain memory

353

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

368

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

370

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

39

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

28

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

54

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

70

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

52

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

87

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

60

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

73

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

108

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

180

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

261

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

325

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

564

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

46

How reproductive organs form

How reproductive organs form

35

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

65

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

57

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

93

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

145

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

103

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

65

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

78

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

85

Functional eggs from human skin cells

Functional eggs from human skin cells

80

Sperm microRNAs regulate paternal transmission of exercise capacity

Sperm microRNAs regulate paternal transmission of ...

87

How sperm achieves energy demands for fertilization

How sperm achieves energy demands for fertilization

106

Repairing damaged lysosomal membrane

Repairing damaged lysosomal membrane

13

Regulating protein production

Regulating protein production

31

How cells eliminate inefficient ribosomes

How cells eliminate inefficient ribosomes

7

A non-coding gene controls cell size

A non-coding gene controls cell size

17

How proteins move during chemical reactions

How proteins move during chemical reactions

84

A molecular gatekeeper that controls protein synthesis

A molecular gatekeeper that controls protein synth...

64

Cleaving mechanically stressed DNA

Cleaving mechanically stressed DNA

45

Intermediate Src-kinase state that accounts for vital biological function

Intermediate Src-kinase state that accounts for vi...

44

Human DNA replication timing and initiation sites unraveled!

Human DNA replication timing and initiation sites ...

80

Biomolecular condensation precedes stress granule formation

Biomolecular condensation precedes stress granule ...

52

Membrane protein network helps transporter protein regulate cell signaling

Membrane protein network helps transporter protein...

51

Allosteric binding site for anthraquinones at the human P2X4 receptor

Allosteric binding site for anthraquinones at the ...

56

How DNA is recognized by proteins that control gene expression

How DNA is recognized by proteins that control gen...

84

A high-protein diet can defeat cholera infection

A high-protein diet can defeat cholera infection

25

Small RNA coded by phage controls infection

Small RNA coded by phage controls infection

44

Could your genes influence the gut microbiome of others?

Could your genes influence the gut microbiome of o...

37

How bacteria resist hostile attacks

How bacteria resist hostile attacks

48

Microbial communities in lungs linked to pneumonia recovery

Microbial communities in lungs linked to pneumonia...

38

Protection against gut infections by Klebsiella strain

Protection against gut infections by Klebsiella st...

45

How circadian rhythms help boost infection recovery

How circadian rhythms help boost infection recovery

85

Shingles vaccine may prevent, slow dementia

Shingles vaccine may prevent, slow dementia

38

Medications change our gut microbiome in predictable ways

Medications change our gut microbiome in predictab...

75

Blood-based immunological signatures for extrapulmonary tuberculosis

Blood-based immunological signatures for extrapulm...

43

How human astroviruses bind to humans cells?

How human astroviruses bind to humans cells?

55

Rebalancing lung repair with immune damage is key to surviving severe influenza

Rebalancing lung repair with immune damage is key ...

48

Toxic gut bacteria may drive ulcerative colitis

Toxic gut bacteria may drive ulcerative colitis

71

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

19

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

101

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

92

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

91

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

99

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

175

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

245

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

276

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

289

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

265

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

284

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

402

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

350

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

57

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

145

How cucumbers got longer?

How cucumbers got longer?

118

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

63

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

77

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

74

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

144

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

350

How plants sense heat during the day

How plants sense heat during the day

312

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

278

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

330

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

328

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

356

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

82

Human T-cell receptor–CD3 complex structure unraveled!

Human T-cell receptor–CD3 complex structure unrave...

51

Key lung immune cells can intensify allergic reactions

Key lung immune cells can intensify allergic react...

205

A new vulnerability of asthma immune cells discovered

A new vulnerability of asthma immune cells discovered

71

Why the 'gut brain' plays a central role for allergies

Why the 'gut brain' plays a central role for aller...

78

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

58

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

98

Oxygen deprivation drives dysfunctional neutrophil immunity

Oxygen deprivation drives dysfunctional neutrophil...

90

Psoriasis-linked gene mutation also impacts gut health

Psoriasis-linked gene mutation also impacts gut he...

87

‘Unconventional’ immune cells to tackle inflammation in the gut

‘Unconventional’ immune cells to tackle inflammati...

96

Predicting if multiple sclerosis medication will be effective for patients

Predicting if multiple sclerosis medication will b...

105

‘Creeping fat’ can worsen Crohn’s disease

‘Creeping fat’ can worsen Crohn’s disease

101

Healthy telomeres key for cancer-fighting T cells

Healthy telomeres key for cancer-fighting T cells

143

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

57

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

344

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

236

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

698

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

323

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

304

Printed skin to replace animal testing

Printed skin to replace animal testing

320

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

299

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

313

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

334

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

342

Redox and pH changes shuts down AQP3 channel

Redox and pH changes shuts down AQP3 channel

46

Mapping the human genome in 4D

Mapping the human genome in 4D

71

Using a microfluidic device to monitor glioblastoma treatment outcomes

Using a microfluidic device to monitor glioblastom...

28

Enzyme catalysis using thiol switching!

Enzyme catalysis using thiol switching!

38

Plant hormone based system for complete degradation of a specific target protein in vivo

Plant hormone based system for complete degradatio...

42

Brain imaging using bioluminescence

Brain imaging using bioluminescence

37

High-resolution brain mapping using X-ray ptychography

High-resolution brain mapping using X-ray ptychogr...

43

How PANX1 permeates different molecules?

How PANX1 permeates different molecules?

34

Structural mechanism behind anti-epilepsy therapies revealed!

Structural mechanism behind anti-epilepsy therapie...

61

First detailed look inside droplet-like structures of compacted DNA

First detailed look inside droplet-like structures...

55

The kinase activity of ZAK at the collided ribosome interface

The kinase activity of ZAK at the collided ribosom...

46

Mapping the molecular blueprint of blood’s secret messengers

Mapping the molecular blueprint of blood’s secret ...

182

CRISPR editing in nondividing human cells (neurons)

CRISPR editing in nondividing human cells (neurons)

75

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

82

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

283

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

264

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

279

How the brain regulates emotions

How the brain regulates emotions

359

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

358

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

342

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

394

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

357

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

368

Link between dietary choices and brain health

Link between dietary choices and brain health

340

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

275

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

408

Research

Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice

Enhanced non-enzymatic H2S generation extends life...

2

Evolving insights into the identity and function of dark microglia

Evolving insights into the identity and function o...

12

The ATG8 E3-like ligases sense lysosomal damage and initiate ESCRT-mediated membrane repair

The ATG8 E3-like ligases sense lysosomal damage an...

13

Lessons in longevity from blood stem cells under protein stress

Lessons in longevity from blood stem cells under p...

13

De novo and inherited dominant variants in U4 and U6 snRNA genes cause retinitis pigmentosa

De novo and inherited dominant variants in U4 and ...

5

Bile acids regulate lipid metabolism through selective actions on fatty acid absorption

Bile acids regulate lipid metabolism through selec...

27

Diet modulates Vibrio cholerae colonization and competitive outcomes with the gut microbiota

Diet modulates Vibrio cholerae colonization and co...

4

Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry

Oligodendrocyte mechanotransduction channel TMEM63...

23

What makes genes burst

What makes genes burst

24

Hepatic adaptation to chronic metabolic stress primes tumorigenesis

Hepatic adaptation to chronic metabolic stress pri...

45

Collision-induced ribosome degradation driven by ribosome competition and translational perturbations

Collision-induced ribosome degradation driven by r...

48

Endolysosomal transport at the crossroads of cellular signaling

Endolysosomal transport at the crossroads of cellu...

25

Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

Chimeric brain models to study human glial-neurona...

26

Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice

Enhanced non-enzymatic H2S generation extends life...

2

Evolving insights into the identity and function of dark microglia

Evolving insights into the identity and function o...

12

The ATG8 E3-like ligases sense lysosomal damage and initiate ESCRT-mediated membrane repair

The ATG8 E3-like ligases sense lysosomal damage an...

13

Lessons in longevity from blood stem cells under protein stress

Lessons in longevity from blood stem cells under p...

13

De novo and inherited dominant variants in U4 and U6 snRNA genes cause retinitis pigmentosa

De novo and inherited dominant variants in U4 and ...

5

Bile acids regulate lipid metabolism through selective actions on fatty acid absorption

Bile acids regulate lipid metabolism through selec...

27

Diet modulates Vibrio cholerae colonization and competitive outcomes with the gut microbiota

Diet modulates Vibrio cholerae colonization and co...

4

Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry

Oligodendrocyte mechanotransduction channel TMEM63...

23

What makes genes burst

What makes genes burst

24

Hepatic adaptation to chronic metabolic stress primes tumorigenesis

Hepatic adaptation to chronic metabolic stress pri...

45

Collision-induced ribosome degradation driven by ribosome competition and translational perturbations

Collision-induced ribosome degradation driven by r...

48

Endolysosomal transport at the crossroads of cellular signaling

Endolysosomal transport at the crossroads of cellu...

25

Structural insights into AQP3 channel closure upon pH and redox changes reveal an autoregulatory molecular mechanism

Structural insights into AQP3 channel closure upon...

14

Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

Chimeric brain models to study human glial-neurona...

26

Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Mapping cellular targets of covalent cancer drugs ...

44

Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel

Dynamic release of extracellular particles after o...

37

Activation of enzymatic catalysis via nucleic acid hybridization affords synergistic coupling of specificity, potency, and signal amplification

Activation of enzymatic catalysis via nucleic acid...

38

Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities

Spatially resolved microRNA expression in tissues:...

49

CaBLAM: a high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

CaBLAM: a high-contrast bioluminescent Ca2+ indica...

41

Nondestructive X-ray tomography of brain tissue ultrastructure

Nondestructive X-ray tomography of brain tissue ul...

36

Integrating axis quantitative trait loci looks beyond cell types and offers insights into brain-related traits

Integrating axis quantitative trait loci looks bey...

62

C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels

C-COMPASS: a user-friendly neural network tool pro...

56

A signature-protein-based approach for accurate and efficient profiling of the human gut virome

A signature-protein-based approach for accurate an...

40

Ultrastructural membrane dynamics of mouse and human cortical synapses

Ultrastructural membrane dynamics of mouse and hum...

39

BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants

BRAIN-MAGNET: A functional genomics atlas for inte...

43

Approaches for identification of 5′ UTR mutations impacting translation and protein production from neurodevelopmental disorder genes

Approaches for identification of 5′ UTR mutations ...

3171

MITOCHONDRIAL DISEASES

MITOCHONDRIAL DISEASES

124

NEURO- MUSCULAR JUNCTION

NEURO- MUSCULAR JUNCTION

74

Caffeine

Caffeine

97

Diabetic Neuropathy

Diabetic Neuropathy

68

Neural Transmission

Neural Transmission

81

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

90

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

293

Potassium Channels

Potassium Channels

144

Calcium channels physiology and Therapeutics uses

Calcium channels physiology and Therapeutics uses

185

Cell Signaling and Communication between Cells

Cell Signaling and Communication between Cells

432

Humoral Immunity

Humoral Immunity

114

Cell Mediated Immunity

Cell Mediated Immunity

283

Telomere

118

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

60333

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1114

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1029

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3009

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

348

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

342

HEAD AND NECK CANCER

HEAD AND NECK CANCER

364

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

208

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

332

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

377

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

319

Gestational diabetes therapeutics

Gestational diabetes therapeutics

315

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

337

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

510

Different types of Alzheimer's disease

Different types of Alzheimer's disease

408

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

369

Alzheimer’s therapeutics

Alzheimer’s therapeutics

367

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

362

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

391

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

332

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

356

APOE in Alzheimer’s

APOE in Alzheimer’s

417

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

487

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

510

Different types of Alzheimer's disease

Different types of Alzheimer's disease

408

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

369

Alzheimer’s therapeutics

Alzheimer’s therapeutics

367

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

362

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

391

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

332

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

356

APOE in Alzheimer’s

APOE in Alzheimer’s

417

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

487

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

343

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

382

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

319

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

319

Gestational diabetes therapeutics

Gestational diabetes therapeutics

315

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

337