Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

14629

Evolutionary Constraints on Total Energy Expenditure

Science Hangouts

Evolutionary Constraints on Total Energy Expenditure

129

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

Science Hangouts

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

120

Science News Highlights

Insular cortex is a link between sensory experience and bodily consequences

News highlights

Insular cortex is a link between sensory experience and bodily consequences

8

Vaccines for Cancer

Science Hangouts

Vaccines for Cancer

5

Targeting kinesins!

News highlights

Targeting kinesins!

15

News

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

18

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

24

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

17

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

26

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

34

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

37

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

23

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

24

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

56

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

20

How blood cells release key signaling lipid

How blood cells release key signaling lipid

39

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

25

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

79

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

56

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

79

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

58

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

49

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

64

Using noise to regulate information flow in neural networks

Using noise to regulate information flow in neural...

49

How can music help us recover from stress?

How can music help us recover from stress?

61

Neural mechanisms of brain multitasking

Neural mechanisms of brain multitasking

68

Where and how Alzheimer's tangles begin

Where and how Alzheimer's tangles begin

73

Atlas of the brain’s striatum

Atlas of the brain’s striatum

74

Psilocybin prevents chemotherapy-induced peripheral neuropathy

Psilocybin prevents chemotherapy-induced periphera...

71

Difference in the gut derived EVs in Parkinson’s disease

Difference in the gut derived EVs in Parkinson’s d...

61

Aberrant receptor tyrosine kinase 4 expression drives Alzheimer’s pathology

Aberrant receptor tyrosine kinase 4 expression dri...

102

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

17

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

42

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

70

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

76

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

91

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

83

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

83

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

90

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

102

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

95

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

92

Protecting cells from iron overload

Protecting cells from iron overload

105

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

107

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

38

Mechanism of obesity relapse

Mechanism of obesity relapse

107

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

93

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

92

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

480

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

159

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

182

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

209

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

250

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

239

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

219

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

250

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

251

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

77

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

39

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

182

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

148

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

55

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

50

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

72

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

144

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

105

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

118

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

105

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

126

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

118

Protein-based data storage

Protein-based data storage

194

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

186

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

198

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

346

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

260

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

306

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

361

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

353

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

316

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

362

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

319

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

389

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

384

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

52

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

86

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

60

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

97

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

80

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

91

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

92

A novel 3D brain tissue model

A novel 3D brain tissue model

129

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

97

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

102

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

179

Reverting aged cells to stem cells

Reverting aged cells to stem cells

242

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

131

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

18

Generational chromosome repair!

Generational chromosome repair!

34

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

35

Is our personality written in our genes?

Is our personality written in our genes?

144

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

60

How chromosomes find their partners

How chromosomes find their partners

123

New gene activation tool!

New gene activation tool!

90

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

94

First complete marmoset genome

First complete marmoset genome

100

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

140

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

134

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

141

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

160

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

57

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

118

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

151

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

153

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

141

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

143

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

238

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

267

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

262

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

282

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

597

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

582

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

577

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

25

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

40

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

55

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

76

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

79

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

106

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

94

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

105

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

127

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

126

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

167

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

149

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

135

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

49

Postbiotics may boost female fertility

Postbiotics may boost female fertility

108

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

123

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

123

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

175

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

192

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

231

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

213

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

269

sncRNAs in sperm aging

sncRNAs in sperm aging

334

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

270

How reproductive organs form

How reproductive organs form

369

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

276

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

24

How blood cells release key signaling lipid

How blood cells release key signaling lipid

39

Transcription of eight letter codon!

Transcription of eight letter codon!

59

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

64

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

54

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

60

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

73

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

77

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

79

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

89

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

100

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

62

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

68

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

26

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

37

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

20

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

51

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

89

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

82

Methylation puts parasites in motion

Methylation puts parasites in motion

66

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

165

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

203

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

117

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

110

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

125

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

116

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

24

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

49

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

50

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

61

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

66

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

74

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

105

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

148

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

158

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

143

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

142

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

168

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

149

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

34

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

70

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

77

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

159

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

135

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

139

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

132

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

133

Cure for dry eye disease

Cure for dry eye disease

163

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

172

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

192

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

170

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

168

Why some people can fight infections better than others?

Why some people can fight infections better than o...

97

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

74

Gene circuits of human immunity

Gene circuits of human immunity

90

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

83

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

99

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

71

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

94

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

84

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

90

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

97

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

93

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

122

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

94

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

76

Air-permeable hydrogels!

Air-permeable hydrogels!

135

Temperature behaves differently in the cell

Temperature behaves differently in the cell

134

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

124

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

166

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

190

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

263

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

542

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

435

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

922

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

535

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

505

Printed skin to replace animal testing

Printed skin to replace animal testing

505

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

23

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

78

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

85

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

62

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

79

Viral RNA elements functional map!

Viral RNA elements functional map!

78

How proteins change shape and move

How proteins change shape and move

84

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

80

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

137

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

83

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

95

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

131

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

532

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

142

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

288

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

483

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

496

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

468

How the brain regulates emotions

How the brain regulates emotions

699

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

547

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

547

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

572

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

538

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

537

Link between dietary choices and brain health

Link between dietary choices and brain health

509

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

495

Research

Linking sensory experience to bodily states in the insular cortex

Linking sensory experience to bodily states in the...

10

Vaccines for Cancer

Vaccines for Cancer

13

A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

A serpin–myeloid axis in pancreatic cancer heterog...

667

A small molecule inhibits Ebola virus entry through glycoprotein stabilization

A small molecule inhibits Ebola virus entry throug...

19

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

33

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

33

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

27

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

30

Streptococcus pyogenes carriage is associated with distinct in vivo transcriptional states but not carrier- specific genotypes

Streptococcus pyogenes carriage is associated with...

965

Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies

Kinesins as dynamic drug targets: structural insig...

40

Engineering the insulin signal peptide to protect human pancreatic beta cells from autoimmune destruction

Engineering the insulin signal peptide to protect ...

40

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Amygdala astrocyte primary cilium mechanisms contr...

48

Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B

Structure and mechanism of human sphingosine-1-pho...

934

Linking sensory experience to bodily states in the insular cortex

Linking sensory experience to bodily states in the...

10

Vaccines for Cancer

Vaccines for Cancer

13

A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

A serpin–myeloid axis in pancreatic cancer heterog...

667

A small molecule inhibits Ebola virus entry through glycoprotein stabilization

A small molecule inhibits Ebola virus entry throug...

19

Streptococcus pyogenes carriage is associated with distinct in vivo transcriptional states but not carrier- specific genotypes

Streptococcus pyogenes carriage is associated with...

965

Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies

Kinesins as dynamic drug targets: structural insig...

40

Engineering the insulin signal peptide to protect human pancreatic beta cells from autoimmune destruction

Engineering the insulin signal peptide to protect ...

40

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Amygdala astrocyte primary cilium mechanisms contr...

48

Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B

Structure and mechanism of human sphingosine-1-pho...

934

Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis

Artery tertiary lymphoid organs encode a pathogeni...

42

Contrastive learning unites sequence and structure in a global representation of protein space

Contrastive learning unites sequence and structure...

886

Obesity and Cancer

Obesity and Cancer

46

Rethinking the origins and functions of adaptive immunity

Rethinking the origins and functions of adaptive i...

54

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

30

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

138

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

249

Automated prototyping of genetic codes

Automated prototyping of genetic codes

260

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

273

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

206

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

94

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

75

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

3009

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

66

Drug screen and machine learning predict neuroprotective agents in a preclinical human model of childhood dementia

Drug screen and machine learning predict neuroprot...

72

Human brain organoids record the passage of time over multiple years

Human brain organoids record the passage of time o...

72

Temporal uncoupling of radial glia lineage progression in cortical organoids

Temporal uncoupling of radial glia lineage progres...

2659

Breeding of Cotton

Breeding of Cotton

640

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

803

THALASSEMIA

THALASSEMIA

951

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

948

NMDA RECEPTORS

462

Neural Development

Neural Development

451

Transcription Factors

Transcription Factors

440

Interferons

392

RABIES

399

ANEMIA

387

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

391

Migraine

315

Dementia

410

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

33

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

33

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

27

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

84

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

86

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

658

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

285

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

3141

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

229

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

61

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIENCE IN RTT SYNDROME

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIE...

3135

Oxidative Signaling in Plants

Oxidative Signaling in Plants

126

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

157

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

523

Gestational diabetes therapeutics

Gestational diabetes therapeutics

619

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

571

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

913

Different types of Alzheimer's disease

Different types of Alzheimer's disease

664

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

600

Alzheimer’s therapeutics

Alzheimer’s therapeutics

729

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

614

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

619

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

562

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

554

APOE in Alzheimer’s

APOE in Alzheimer’s

782

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

709

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

913

Different types of Alzheimer's disease

Different types of Alzheimer's disease

664

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

600

Alzheimer’s therapeutics

Alzheimer’s therapeutics

729

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

614

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

619

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

562

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

554

APOE in Alzheimer’s

APOE in Alzheimer’s

782

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

709

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

561

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

717

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

498

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

523

Gestational diabetes therapeutics

Gestational diabetes therapeutics

619

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

571