Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

14800

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

9

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

11

Science News Highlights

Mental privacy and brain–computer interfaces

News highlights

Mental privacy and brain–computer interfaces

9

Moving intentions from brains to machines

News highlights

Moving intentions from brains to machines

14

Insular cortex is a link between sensory experience and bodily consequences

News highlights

Insular cortex is a link between sensory experience an...

20

News

Intermittent fasting shows promise in slowing Huntington’s disease progression

Intermittent fasting shows promise in slowing Hunt...

7

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

10

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

10

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

10

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

21

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

18

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

20

Locus coeruleus noradrenaline neurons mapped!

Locus coeruleus noradrenaline neurons mapped!

36

Psychedelics and anesthetics create mirror image patterns in the brain

Psychedelics and anesthetics create mirror image p...

25

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

34

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

69

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

25

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

38

Intermittent fasting shows promise in slowing Huntington’s disease progression

Intermittent fasting shows promise in slowing Hunt...

7

Locus coeruleus noradrenaline neurons mapped!

Locus coeruleus noradrenaline neurons mapped!

36

Psychedelics and anesthetics create mirror image patterns in the brain

Psychedelics and anesthetics create mirror image p...

25

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

68

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

95

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

68

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

56

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

69

Using noise to regulate information flow in neural networks

Using noise to regulate information flow in neural...

56

How can music help us recover from stress?

How can music help us recover from stress?

77

Neural mechanisms of brain multitasking

Neural mechanisms of brain multitasking

80

Where and how Alzheimer's tangles begin

Where and how Alzheimer's tangles begin

79

Atlas of the brain’s striatum

Atlas of the brain’s striatum

79

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

34

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

24

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

52

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

74

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

77

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

94

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

85

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

84

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

93

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

104

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

96

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

96

Protecting cells from iron overload

Protecting cells from iron overload

107

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

46

Mechanism of obesity relapse

Mechanism of obesity relapse

126

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

100

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

94

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

483

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

160

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

183

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

213

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

253

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

242

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

221

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

251

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

254

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

10

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

20

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

69

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

85

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

45

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

190

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

162

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

61

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

53

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

74

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

147

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

106

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

119

Protein-based data storage

Protein-based data storage

196

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

189

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

200

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

348

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

262

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

307

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

365

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

355

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

318

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

363

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

321

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

391

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

386

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

68

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

88

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

62

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

98

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

83

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

96

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

96

A novel 3D brain tissue model

A novel 3D brain tissue model

130

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

100

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

106

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

181

Reverting aged cells to stem cells

Reverting aged cells to stem cells

244

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

132

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

18

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

25

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

38

Generational chromosome repair!

Generational chromosome repair!

41

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

44

Is our personality written in our genes?

Is our personality written in our genes?

147

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

64

How chromosomes find their partners

How chromosomes find their partners

126

New gene activation tool!

New gene activation tool!

92

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

97

First complete marmoset genome

First complete marmoset genome

103

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

144

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

136

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

10

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

64

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

120

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

154

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

155

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

142

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

146

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

242

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

271

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

265

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

284

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

599

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

585

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

30

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

49

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

61

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

78

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

81

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

108

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

96

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

107

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

129

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

127

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

168

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

151

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

137

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

50

Postbiotics may boost female fertility

Postbiotics may boost female fertility

110

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

125

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

125

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

178

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

193

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

234

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

214

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

271

sncRNAs in sperm aging

sncRNAs in sperm aging

336

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

270

How reproductive organs form

How reproductive organs form

369

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

279

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

29

How blood cells release key signaling lipid

How blood cells release key signaling lipid

50

Transcription of eight letter codon!

Transcription of eight letter codon!

64

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

66

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

55

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

60

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

76

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

79

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

79

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

90

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

101

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

63

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

70

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

21

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

35

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

57

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

25

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

52

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

95

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

88

Methylation puts parasites in motion

Methylation puts parasites in motion

66

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

166

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

204

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

120

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

110

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

127

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

55

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

56

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

51

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

62

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

66

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

74

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

106

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

150

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

158

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

146

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

142

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

168

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

152

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

10

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

53

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

71

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

77

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

160

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

136

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

141

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

134

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

135

Cure for dry eye disease

Cure for dry eye disease

166

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

178

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

195

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

172

Why some people can fight infections better than others?

Why some people can fight infections better than o...

100

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

81

Gene circuits of human immunity

Gene circuits of human immunity

93

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

87

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

101

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

71

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

97

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

86

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

91

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

99

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

93

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

122

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

95

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

79

Air-permeable hydrogels!

Air-permeable hydrogels!

136

Temperature behaves differently in the cell

Temperature behaves differently in the cell

135

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

125

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

167

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

190

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

263

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

544

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

437

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

923

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

536

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

508

Printed skin to replace animal testing

Printed skin to replace animal testing

506

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

30

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

81

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

87

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

64

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

80

Viral RNA elements functional map!

Viral RNA elements functional map!

78

How proteins change shape and move

How proteins change shape and move

84

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

82

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

139

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

83

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

96

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

136

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

533

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

144

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

290

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

484

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

498

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

469

How the brain regulates emotions

How the brain regulates emotions

700

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

552

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

549

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

573

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

542

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

537

Link between dietary choices and brain health

Link between dietary choices and brain health

510

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

496

Research

Hyodeoxycholic acid suppresses hepatic steatosis in a PPARα-dependent manner via distinct GLP-1- and iNKT cell-mediated pathways

Hyodeoxycholic acid suppresses hepatic steatosis i...

12

REAP1/AtSWAP70 integrates RAB5 and ROP signalling during sexual reproduction

REAP1/AtSWAP70 integrates RAB5 and ROP signalling ...

11

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

17

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

14

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

13

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

21

When minds become data: brain–computer interfaces and the future of mental privacy

When minds become data: brain–computer interfaces ...

672

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

20

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

26

Topographic structure and function of locus coeruleus noradrenaline neurons

Topographic structure and function of locus coerul...

518

Moving intentions from brains to machines

Moving intentions from brains to machines

31

Opposite network patterns of integration- segregation in psychedelic and sedated states of consciousness

Opposite network patterns of integration- segregat...

28

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression in mice

MALT1 protease inhibition restrains glioblastoma p...

49

Hyodeoxycholic acid suppresses hepatic steatosis in a PPARα-dependent manner via distinct GLP-1- and iNKT cell-mediated pathways

Hyodeoxycholic acid suppresses hepatic steatosis i...

12

REAP1/AtSWAP70 integrates RAB5 and ROP signalling during sexual reproduction

REAP1/AtSWAP70 integrates RAB5 and ROP signalling ...

11

When minds become data: brain–computer interfaces and the future of mental privacy

When minds become data: brain–computer interfaces ...

672

Topographic structure and function of locus coeruleus noradrenaline neurons

Topographic structure and function of locus coerul...

518

Moving intentions from brains to machines

Moving intentions from brains to machines

31

Opposite network patterns of integration- segregation in psychedelic and sedated states of consciousness

Opposite network patterns of integration- segregat...

28

MALT1 protease inhibition restrains glioblastoma progression by reversing tumor-associated macrophage-dependent immunosuppression in mice

MALT1 protease inhibition restrains glioblastoma p...

49

Predicting genome-wide functional constraints with GPN-Star

Predicting genome-wide functional constraints with...

35

Integrated signatures define mutational processes in prostate cancer

Integrated signatures define mutational processes ...

28

Linking sensory experience to bodily states in the insular cortex

Linking sensory experience to bodily states in the...

87

Vaccines for Cancer

Vaccines for Cancer

37

A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion

A serpin–myeloid axis in pancreatic cancer heterog...

859

A small molecule inhibits Ebola virus entry through glycoprotein stabilization

A small molecule inhibits Ebola virus entry throug...

37

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

21

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

20

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

26

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

68

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

168

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

274

Automated prototyping of genetic codes

Automated prototyping of genetic codes

276

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

276

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

206

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

95

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

76

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

3011

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

66

Breeding of Cotton

Breeding of Cotton

660

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

837

THALASSEMIA

THALASSEMIA

979

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

976

NMDA RECEPTORS

462

Neural Development

Neural Development

452

Transcription Factors

Transcription Factors

441

Interferons

393

RABIES

399

ANEMIA

389

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

391

Migraine

317

Dementia

410

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

17

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

14

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

13

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

75

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

724

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

67

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

121

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

91

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

659

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

287

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

3141

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

230

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

63

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

524

Gestational diabetes therapeutics

Gestational diabetes therapeutics

621

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

574

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

914

Different types of Alzheimer's disease

Different types of Alzheimer's disease

664

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

600

Alzheimer’s therapeutics

Alzheimer’s therapeutics

731

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

616

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

622

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

564

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

556

APOE in Alzheimer’s

APOE in Alzheimer’s

784

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

712

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

914

Different types of Alzheimer's disease

Different types of Alzheimer's disease

664

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

600

Alzheimer’s therapeutics

Alzheimer’s therapeutics

731

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

616

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

622

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

564

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

556

APOE in Alzheimer’s

APOE in Alzheimer’s

784

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

712

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

563

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

721

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

501

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

524

Gestational diabetes therapeutics

Gestational diabetes therapeutics

621

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

574