Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

13755

Evolutionary Constraints on Total Energy Expenditure

Science Hangouts

Evolutionary Constraints on Total Energy Expenditure

69

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

Science Hangouts

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

74

Science News Highlights

Ferroptosis in pancreatic cancer

Science Hangouts

Ferroptosis in pancreatic cancer

12

Light-induced reprogramming of pain signaling

News highlights

Light-induced reprogramming of pain signaling

17

Cell death in cancer

News highlights

Cell death in cancer

24

News

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

12

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

13

Psilocybin prevents chemotherapy-induced peripheral neuropathy

Psilocybin prevents chemotherapy-induced periphera...

12

Gene expression and metabolomics in an aging women

Gene expression and metabolomics in an aging women

18

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

25

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

32

Difference in the gut derived EVs in Parkinson’s disease

Difference in the gut derived EVs in Parkinson’s d...

27

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

16

Aberrant receptor tyrosine kinase 4 expression drives Alzheimer’s pathology

Aberrant receptor tyrosine kinase 4 expression dri...

50

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

34

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

31

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

38

Cognitive decline in human aging from oligodendrocyte dysfunction

Cognitive decline in human aging from oligodendroc...

45

Psilocybin prevents chemotherapy-induced peripheral neuropathy

Psilocybin prevents chemotherapy-induced periphera...

12

Difference in the gut derived EVs in Parkinson’s disease

Difference in the gut derived EVs in Parkinson’s d...

27

Aberrant receptor tyrosine kinase 4 expression drives Alzheimer’s pathology

Aberrant receptor tyrosine kinase 4 expression dri...

50

Cognitive decline in human aging from oligodendrocyte dysfunction

Cognitive decline in human aging from oligodendroc...

45

How social isolation drives alcohol consumption

How social isolation drives alcohol consumption

39

Mechanism to regulate chronic neuropathic pain identified!

Mechanism to regulate chronic neuropathic pain ide...

56

How the brain represents meaning across different languages

How the brain represents meaning across different ...

41

Brain’s language network remains intact in old age

Brain’s language network remains intact in old age

40

Sleep and exercise may protect memory after sleep deprivation

Sleep and exercise may protect memory after sleep ...

46

Compound lowering human blood marker slows ALS

Compound lowering human blood marker slows ALS

67

Rewiring of protein interaction networks by autism mutations

Rewiring of protein interaction networks by autism...

80

Two prefrontal-subcortical circuits decide whether we are in control

Two prefrontal-subcortical circuits decide whether...

82

Hippocampal neurogenesis is dysregulated in depression

Hippocampal neurogenesis is dysregulated in depres...

67

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

31

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

51

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

59

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

57

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

60

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

67

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

77

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

70

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

70

Protecting cells from iron overload

Protecting cells from iron overload

88

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

83

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

78

Tumor-secreted protein promotes lung metastasis

Tumor-secreted protein promotes lung metastasis

63

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

66

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

446

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

136

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

161

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

174

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

223

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

218

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

201

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

227

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

231

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

252

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

232

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

248

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

13

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

16

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

34

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

124

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

76

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

93

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

81

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

96

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

103

A foundation model for sleep identifies health risks

A foundation model for sleep identifies health risks

84

AI discovers variation in local brain aging and cognition across human adulthood

AI discovers variation in local brain aging and co...

109

AI tool miniaturize and modify proteins without sacrificing function

AI tool miniaturize and modify proteins without sa...

287

Structure of neuronal epilepsy linked protein unraveled!

Structure of neuronal epilepsy linked protein unra...

123

Protein-based data storage

Protein-based data storage

168

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

168

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

177

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

320

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

242

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

287

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

339

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

329

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

301

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

335

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

306

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

359

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

370

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

53

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

44

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

83

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

62

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

66

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

72

A novel 3D brain tissue model

A novel 3D brain tissue model

103

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

73

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

83

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

149

Reverting aged cells to stem cells

Reverting aged cells to stem cells

218

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

107

Mechanism linking inflammation and prevention of neuron formation identified!

Mechanism linking inflammation and prevention of n...

146

Gene expression and metabolomics in an aging women

Gene expression and metabolomics in an aging women

18

How chromosomes find their partners

How chromosomes find their partners

81

New gene activation tool!

New gene activation tool!

61

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

65

First complete marmoset genome

First complete marmoset genome

81

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

116

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

112

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

126

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

132

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

160

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

179

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

187

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

194

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

94

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

129

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

132

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

122

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

117

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

213

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

249

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

247

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

266

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

578

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

570

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

561

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

673

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

56

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

63

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

86

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

76

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

89

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

110

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

103

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

146

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

129

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

117

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

139

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

146

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

166

Postbiotics may boost female fertility

Postbiotics may boost female fertility

80

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

106

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

104

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

154

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

174

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

213

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

200

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

246

sncRNAs in sperm aging

sncRNAs in sperm aging

317

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

252

How reproductive organs form

How reproductive organs form

355

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

261

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

254

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

12

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

25

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

38

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

49

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

62

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

78

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

84

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

49

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

42

Hidden function of a protein to influence leukemia drug

Hidden function of a protein to influence leukemia...

46

How antibiotics work inhibiting RNA polymerase?

How antibiotics work inhibiting RNA polymerase?

65

Mitochondria act as sensors for essential iron molecule

Mitochondria act as sensors for essential iron mol...

74

Evaluating gut microbial and host proteins in health and disease

Evaluating gut microbial and host proteins in heal...

74

Methylation puts parasites in motion

Methylation puts parasites in motion

47

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

140

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

182

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

98

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

93

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

105

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

98

Fasting primes gut microbiome to improve intestinal recovery after radiation treatment

Fasting primes gut microbiome to improve intestina...

103

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

111

Structural insight into the mechanism of bacterial pili retraction

Structural insight into the mechanism of bacterial...

118

Microbiota’s hidden role in mosquito-borne disease

Microbiota’s hidden role in mosquito-borne disease

137

Colorectal cancer signature

Colorectal cancer signature

105

How bacteria use circadian clocks to colonize

How bacteria use circadian clocks to colonize

98

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

32

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

54

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

56

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

88

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

131

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

143

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

128

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

121

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

151

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

125

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

136

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

161

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

155

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

58

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

65

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

138

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

112

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

118

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

116

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

114

Cure for dry eye disease

Cure for dry eye disease

143

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

152

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

176

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

153

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

153

Nicotine Biosynthesis!

Nicotine Biosynthesis!

285

Why some people can fight infections better than others?

Why some people can fight infections better than o...

72

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

54

Gene circuits of human immunity

Gene circuits of human immunity

70

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

69

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

71

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

58

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

77

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

72

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

70

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

85

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

75

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

107

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

79

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

50

Air-permeable hydrogels!

Air-permeable hydrogels!

115

Temperature behaves differently in the cell

Temperature behaves differently in the cell

116

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

116

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

154

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

171

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

248

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

528

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

426

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

907

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

520

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

490

Printed skin to replace animal testing

Printed skin to replace animal testing

492

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

55

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

73

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

50

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

49

Viral RNA elements functional map!

Viral RNA elements functional map!

58

How proteins change shape and move

How proteins change shape and move

66

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

68

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

120

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

72

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

78

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

111

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

517

Molecular map of liver disease

Molecular map of liver disease

104

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

112

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

270

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

464

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

472

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

455

How the brain regulates emotions

How the brain regulates emotions

676

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

531

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

530

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

561

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

527

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

524

Link between dietary choices and brain health

Link between dietary choices and brain health

498

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

482

Research

ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport

ER sensing of lipid metabolism drives PRA family-d...

10

The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging, and social behavior

The complete gustatory connectome of adult Drosoph...

10

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Psilocybin prevents chemotherapy-induced periphera...

10

Ferroptosis in cancer toward molecular insights and clinical translation in pancreatic cancer

Ferroptosis in cancer toward molecular insights an...

36

Protein entanglement misfolding influences whether proteins undergo proteasomal degradation or persist in near-native misfolded states

Protein entanglement misfolding influences whether...

17

Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions

Metabolic atlas of early human cortex reveals glyc...

35

Gut microbiota-derived extracellular vesicles in Parkinson’s disease

Gut microbiota-derived extracellular vesicles in P...

32

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

26

Reprogramming pain signaling through photopharmacology

Reprogramming pain signaling through photopharmaco...

37

Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology

Aberrant excitatory neuronal ERBB4 promotes Alzhei...

45

A quantitative approach for defining the degradability landscape of protein degraders

A quantitative approach for defining the degradabi...

42

Cell autonomous regional differences in oligodendrocyte lineage development and responses to oncohistone H3.3 K27M

Cell autonomous regional differences in oligodendr...

41

Cell death in cancer

Cell death in cancer

89

ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport

ER sensing of lipid metabolism drives PRA family-d...

10

The complete gustatory connectome of adult Drosophila reveals how taste guides feeding, foraging, and social behavior

The complete gustatory connectome of adult Drosoph...

10

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Psilocybin prevents chemotherapy-induced periphera...

10

Ferroptosis in cancer toward molecular insights and clinical translation in pancreatic cancer

Ferroptosis in cancer toward molecular insights an...

36

Protein entanglement misfolding influences whether proteins undergo proteasomal degradation or persist in near-native misfolded states

Protein entanglement misfolding influences whether...

17

Metabolic atlas of early human cortex reveals glycolytic remodeling and pentose phosphate pathway control of cell fate transitions

Metabolic atlas of early human cortex reveals glyc...

35

Gut microbiota-derived extracellular vesicles in Parkinson’s disease

Gut microbiota-derived extracellular vesicles in P...

32

Reprogramming pain signaling through photopharmacology

Reprogramming pain signaling through photopharmaco...

37

Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology

Aberrant excitatory neuronal ERBB4 promotes Alzhei...

45

A quantitative approach for defining the degradability landscape of protein degraders

A quantitative approach for defining the degradabi...

42

Cell autonomous regional differences in oligodendrocyte lineage development and responses to oncohistone H3.3 K27M

Cell autonomous regional differences in oligodendr...

41

Cell death in cancer

Cell death in cancer

89

Transcription elongation by RNA polymerase II: from regulatory complexity to disease

Transcription elongation by RNA polymerase II: fro...

987

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

26

Automated prototyping of genetic codes

Automated prototyping of genetic codes

61

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

93

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

96

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

72

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

55

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

2985

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

53

Drug screen and machine learning predict neuroprotective agents in a preclinical human model of childhood dementia

Drug screen and machine learning predict neuroprot...

57

Human brain organoids record the passage of time over multiple years

Human brain organoids record the passage of time o...

58

Temporal uncoupling of radial glia lineage progression in cortical organoids

Temporal uncoupling of radial glia lineage progres...

2647

Trans-regulatory gene mapping prioritizes disease drivers in asthma

Trans-regulatory gene mapping prioritizes disease ...

61

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across enti...

733

Breeding of Cotton

Breeding of Cotton

439

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

603

THALASSEMIA

THALASSEMIA

749

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

734

NMDA RECEPTORS

444

Neural Development

Neural Development

429

Transcription Factors

Transcription Factors

422

Interferons

372

RABIES

382

ANEMIA

367

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

378

Migraine

302

Dementia

392

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

93

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

117

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

1716

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

95

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

47

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIENCE IN RTT SYNDROME

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIE...

3118

Oxidative Signaling in Plants

Oxidative Signaling in Plants

104

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

128

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

159910

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1960

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1622

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

6650

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

541

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

511

Gestational diabetes therapeutics

Gestational diabetes therapeutics

606

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

555

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

881

Different types of Alzheimer's disease

Different types of Alzheimer's disease

650

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

586

Alzheimer’s therapeutics

Alzheimer’s therapeutics

709

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

595

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

600

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

541

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

539

APOE in Alzheimer’s

APOE in Alzheimer’s

757

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

691

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

881

Different types of Alzheimer's disease

Different types of Alzheimer's disease

650

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

586

Alzheimer’s therapeutics

Alzheimer’s therapeutics

709

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

595

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

600

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

541

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

539

APOE in Alzheimer’s

APOE in Alzheimer’s

757

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

691

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

550

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

699

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

481

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

511

Gestational diabetes therapeutics

Gestational diabetes therapeutics

606

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

555