Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

15164

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

37

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

38

Science News Highlights

Safe and broad-spectrum α2AAR agonist act as an oral analgesic

News highlights

Safe and broad-spectrum α2AAR agonist act as an oral analgesic

8

Fluorescence anisotropy for endogenous gene expression detection

News highlights

Fluorescence anisotropy for endogenous gene expression...

12

Thyroid Cancer

News highlights

Thyroid Cancer

16

News

Brain activity can predict a risky decision before it’s made

Brain activity can predict a risky decision before...

5

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

8

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

9

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

17

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

25

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

25

Why some Huntington disease patients decline years earlier

Why some Huntington disease patients decline years...

24

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

29

How a protein shapes the cell membrane

How a protein shapes the cell membrane

36

Mitochondrial transfer from bone marrow transplant in mitochondrial disease

Mitochondrial transfer from bone marrow transplant...

64

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

36

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

62

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

65

Brain activity can predict a risky decision before it’s made

Brain activity can predict a risky decision before...

5

Why some Huntington disease patients decline years earlier

Why some Huntington disease patients decline years...

24

Mitochondrial transfer from bone marrow transplant in mitochondrial disease

Mitochondrial transfer from bone marrow transplant...

64

Autism-risk mutations reveal two opposing patterns of brain gene activity

Autism-risk mutations reveal two opposing patterns...

41

TRPM2 is a direct transducer for chronic pain

TRPM2 is a direct transducer for chronic pain

33

Intermittent fasting shows promise in slowing Huntington’s disease progression

Intermittent fasting shows promise in slowing Hunt...

56

Locus coeruleus noradrenaline neurons mapped!

Locus coeruleus noradrenaline neurons mapped!

80

Psychedelics and anesthetics create mirror image patterns in the brain

Psychedelics and anesthetics create mirror image p...

48

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

84

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

115

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

82

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

68

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

78

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

17

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

29

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

47

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

63

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

46

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

60

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

81

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

83

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

102

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

92

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

92

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

100

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

109

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

52

Mechanism of obesity relapse

Mechanism of obesity relapse

158

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

109

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

100

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

493

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

166

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

191

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

224

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

260

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

252

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

228

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

261

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

259

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

62

AI language models for aging biology

AI language models for aging biology

76

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

55

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

68

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

111

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

98

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

61

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

199

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

180

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

69

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

62

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

89

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

151

Protein-based data storage

Protein-based data storage

203

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

197

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

206

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

353

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

271

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

315

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

370

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

360

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

327

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

369

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

329

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

407

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

392

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

92

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

93

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

67

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

109

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

89

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

112

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

103

A novel 3D brain tissue model

A novel 3D brain tissue model

136

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

114

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

111

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

194

Reverting aged cells to stem cells

Reverting aged cells to stem cells

254

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

137

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

29

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

44

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

43

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

42

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

54

Generational chromosome repair!

Generational chromosome repair!

52

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

52

Is our personality written in our genes?

Is our personality written in our genes?

157

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

75

How chromosomes find their partners

How chromosomes find their partners

137

New gene activation tool!

New gene activation tool!

100

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

110

First complete marmoset genome

First complete marmoset genome

108

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

25

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

47

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

76

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

128

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

159

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

162

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

149

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

152

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

254

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

278

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

272

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

294

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

605

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

41

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

60

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

76

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

88

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

87

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

113

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

103

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

111

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

135

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

132

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

174

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

157

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

144

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

65

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

57

Postbiotics may boost female fertility

Postbiotics may boost female fertility

121

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

130

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

131

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

189

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

198

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

240

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

219

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

282

sncRNAs in sperm aging

sncRNAs in sperm aging

341

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

274

How reproductive organs form

How reproductive organs form

374

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

9

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

25

How a protein shapes the cell membrane

How a protein shapes the cell membrane

36

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

59

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

42

How blood cells release key signaling lipid

How blood cells release key signaling lipid

59

Transcription of eight letter codon!

Transcription of eight letter codon!

73

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

73

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

61

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

66

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

90

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

95

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

83

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

46

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

51

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

89

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

43

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

57

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

102

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

91

Methylation puts parasites in motion

Methylation puts parasites in motion

70

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

171

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

208

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

130

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

116

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

131

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

90

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

60

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

63

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

68

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

70

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

78

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

110

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

157

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

163

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

148

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

144

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

173

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

155

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

36

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

35

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

70

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

79

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

88

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

164

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

140

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

145

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

139

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

138

Cure for dry eye disease

Cure for dry eye disease

174

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

184

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

200

Why some people can fight infections better than others?

Why some people can fight infections better than o...

103

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

86

Gene circuits of human immunity

Gene circuits of human immunity

103

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

93

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

110

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

75

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

98

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

90

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

92

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

103

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

95

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

124

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

98

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

8

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

89

Air-permeable hydrogels!

Air-permeable hydrogels!

141

Temperature behaves differently in the cell

Temperature behaves differently in the cell

140

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

127

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

171

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

195

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

270

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

551

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

443

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

927

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

541

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

519

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

44

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

84

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

91

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

70

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

84

Viral RNA elements functional map!

Viral RNA elements functional map!

80

How proteins change shape and move

How proteins change shape and move

86

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

89

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

144

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

88

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

99

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

138

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

535

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

156

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

297

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

489

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

510

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

472

How the brain regulates emotions

How the brain regulates emotions

704

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

555

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

557

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

577

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

544

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

541

Link between dietary choices and brain health

Link between dietary choices and brain health

513

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

503

Research

Intracranial recordings in humans reveal differential contributions of medial and lateral orbitofrontal cortex to approach–avoidance decision-making

Intracranial recordings in humans reveal different...

5

Synthesis of poly(4HB-co-PhLA) and poly(3HB-co-4HB-co-PhLA) as sustainable hot-melt adhesives using engineered Escherichia coli

Synthesis of poly(4HB-co-PhLA) and poly(3HB-co-4HB...

8

RNA-dependent SFPQ condensates coordinate multidimensional regulation of extra-long neuronal genes

RNA-dependent SFPQ condensates coordinate multidim...

9

Discovery of a peripherally restricted α2AAR agonist as a safe and broad-spectrum oral analgesic

Discovery of a peripherally restricted α2AAR agoni...

485

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

20

Associations between diet quality, epigenetic aging and epigenome in two population- based cohorts

Associations between diet quality, epigenetic agi...

22

Loss of interruption in the HTT CAG repeat is associated with somatic expansion and loss of medium spiny neurons in Huntington’s disease

Loss of interruption in the HTT CAG repeat is asso...

25

The Nobel Prize in Chemistry 2026

The Nobel Prize in Chemistry 2026

24

Vascular signals coordinate cerebellar circuitry development

Vascular signals coordinate cerebellar circuitry d...

823

Thyroid Cancer

24

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

218

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

32

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

28

Intracranial recordings in humans reveal differential contributions of medial and lateral orbitofrontal cortex to approach–avoidance decision-making

Intracranial recordings in humans reveal different...

5

Synthesis of poly(4HB-co-PhLA) and poly(3HB-co-4HB-co-PhLA) as sustainable hot-melt adhesives using engineered Escherichia coli

Synthesis of poly(4HB-co-PhLA) and poly(3HB-co-4HB...

8

RNA-dependent SFPQ condensates coordinate multidimensional regulation of extra-long neuronal genes

RNA-dependent SFPQ condensates coordinate multidim...

9

Discovery of a peripherally restricted α2AAR agonist as a safe and broad-spectrum oral analgesic

Discovery of a peripherally restricted α2AAR agoni...

485

Associations between diet quality, epigenetic aging and epigenome in two population- based cohorts

Associations between diet quality, epigenetic agi...

22

Loss of interruption in the HTT CAG repeat is associated with somatic expansion and loss of medium spiny neurons in Huntington’s disease

Loss of interruption in the HTT CAG repeat is asso...

25

The Nobel Prize in Chemistry 2026

The Nobel Prize in Chemistry 2026

24

Vascular signals coordinate cerebellar circuitry development

Vascular signals coordinate cerebellar circuitry d...

823

Thyroid Cancer

24

Transcription in check at DNA double-strand breaks

Transcription in check at DNA double-strand breaks

27

Structures of EHD2 filaments on curved membranes provide a model for caveolar neck stabilization

Structures of EHD2 filaments on curved membranes p...

21

Myeloid cell replacement induces intercellular mitochondrial transfer and restores metabolism in a mouse model of mitochondrial disease

Myeloid cell replacement induces intercellular mit...

30

The Nobel Prize in Physics 2026

The Nobel Prize in Physics 2026

21

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

20

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

30

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

41

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

47

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

42

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

44

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

78

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

172

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

279

Automated prototyping of genetic codes

Automated prototyping of genetic codes

281

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

281

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

212

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

97

Breeding of Cotton

Breeding of Cotton

673

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

856

THALASSEMIA

THALASSEMIA

998

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

994

NMDA RECEPTORS

472

Neural Development

Neural Development

459

Transcription Factors

Transcription Factors

444

Interferons

398

RABIES

410

ANEMIA

405

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

396

Migraine

328

Dementia

418

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

218

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

32

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

28

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

52

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2359

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

37

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

91

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

736

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

80

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

128

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

95

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

661

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

292

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

529

Gestational diabetes therapeutics

Gestational diabetes therapeutics

625

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

577

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

918

Different types of Alzheimer's disease

Different types of Alzheimer's disease

670

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

605

Alzheimer’s therapeutics

Alzheimer’s therapeutics

739

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

624

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

634

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

573

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

567

APOE in Alzheimer’s

APOE in Alzheimer’s

796

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

720

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

918

Different types of Alzheimer's disease

Different types of Alzheimer's disease

670

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

605

Alzheimer’s therapeutics

Alzheimer’s therapeutics

739

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

624

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

634

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

573

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

567

APOE in Alzheimer’s

APOE in Alzheimer’s

796

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

720

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

567

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

730

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

515

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

529

Gestational diabetes therapeutics

Gestational diabetes therapeutics

625

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

577