Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

1605

Circadian Medicine

Science Hangouts

Circadian Medicine

22

Look who is weaving the neural web? Control of synaptic connectivity by astrocytes

Science Hangouts

Look who is weaving the neural web? Control of synaptic connectivity by astrocytes

27

Science News Highlights

Senescence–autophagy axis in idiopathic pulmonary fibrosis

News highlights

Senescence–autophagy axis in idiopathic pulmonary fibrosis

5

Cullin–RING receptors in rare disease biology

News highlights

Cullin–RING receptors in rare disease biology

6

Nutrient stress in DNA damage

News highlights

Nutrient stress in DNA damage

10

News

Brain's addiction circuit identified!

Brain's addiction circuit identified!

16

What changes happen in the aging brain?

What changes happen in the aging brain?

16

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

29

Enhancing gut-brain communication reversed cognitive decline in aging mice

Enhancing gut-brain communication reversed cogniti...

38

How deadly Marburg virus enters human cells

How deadly Marburg virus enters human cells

31

How ageing promotes metastasis

How ageing promotes metastasis

33

Combination therapy to treat glioblastoma

Combination therapy to treat glioblastoma

35

Mechanism of blood vessel signaling bias

Mechanism of blood vessel signaling bias

34

Microglia promote Alzheimer’s plaque formation!

Microglia promote Alzheimer’s plaque formation!

43

Microbiota derived nicotinic acid protects colon tissue

Microbiota derived nicotinic acid protects colon t...

48

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

35

Recent pandemic viruses jumped to humans without prior adaptation

Recent pandemic viruses jumped to humans without p...

29

Exercise triggers memory-related brain 'ripples' in humans

Exercise triggers memory-related brain 'ripples' i...

57

Brain's addiction circuit identified!

Brain's addiction circuit identified!

16

What changes happen in the aging brain?

What changes happen in the aging brain?

16

Microglia promote Alzheimer’s plaque formation!

Microglia promote Alzheimer’s plaque formation!

43

Exercise triggers memory-related brain 'ripples' in humans

Exercise triggers memory-related brain 'ripples' i...

57

Changes in protein shape to detect and track Alzheimer’s disease

Changes in protein shape to detect and track Alzhe...

34

High-altitude survival gene may help reverse nerve damage

High-altitude survival gene may help reverse nerve...

52

Cell-type specific TDP-43 pathology in the motor cortex

Cell-type specific TDP-43 pathology in the motor c...

42

Pathway controlling forelimb movement identified!

Pathway controlling forelimb movement identified!

139

Oligodendrocyte molecular perturbations associated with tau in Alzheimer’s

Oligodendrocyte molecular perturbations associated...

68

Potassium channels functionality is coupled to trafficking!

Potassium channels functionality is coupled to tra...

47

Tubulin prevents toxic protein clump formation

Tubulin prevents toxic protein clump formation

59

New cellular immunotherapy approach for Alzheimer’s disease

New cellular immunotherapy approach for Alzheimer’...

83

Learning makes brain cells work together, not apart

Learning makes brain cells work together, not apart

42

How ageing promotes metastasis

How ageing promotes metastasis

33

Combination therapy to treat glioblastoma

Combination therapy to treat glioblastoma

35

How vitamin B2 could play a role in cancer therapies

How vitamin B2 could play a role in cancer therapies

47

Src kinase on the cell surface in cancer

Src kinase on the cell surface in cancer

59

Ketone supplementation improves immunotherapy

Ketone supplementation improves immunotherapy

54

Providing T cells with a sugar source to fight solid tumors

Providing T cells with a sugar source to fight sol...

56

Cancer stress protein helps tumors hide from immunity

Cancer stress protein helps tumors hide from immunity

62

Pancreatic tumor cells regulate autophagy by sensing ECM

Pancreatic tumor cells regulate autophagy by sensi...

60

Virus-based therapy boosts anti-cancer immune responses to brain cancer

Virus-based therapy boosts anti-cancer immune resp...

63

Identifying aggressive prostate cancer with multi-omics

Identifying aggressive prostate cancer with multi-...

71

Radiotherapy is more effective when administered at the right time of day

Radiotherapy is more effective when administered a...

56

Chronic cellular stress promotes liver cancer but also enhances immunotherapy efficiency

Chronic cellular stress promotes liver cancer but ...

73

How extra cellular matrix boosts triple negative breast cancer’s ability to metastasize

How extra cellular matrix boosts triple negative b...

70

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

43

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

131

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

44

Human islet cell electrical maturation

Human islet cell electrical maturation

52

Red blood cells soak up sugar at high altitude, protecting against diabetes

Red blood cells soak up sugar at high altitude, pr...

83

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

83

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

100

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

73

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

96

Exposure to natural light improves metabolic health

Exposure to natural light improves metabolic health

126

Gut microbial bileacids in infancy may influence the risk of type 1 diabetes

Gut microbial bileacids in infancy may influence t...

78

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

77

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

197

Artificial intelligence decodes tissue characteristics of type 2 diabetes

Artificial intelligence decodes tissue characteris...

34

Rapid Evolution of Complex Multi-mutant Proteins

Rapid Evolution of Complex Multi-mutant Proteins

64

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

73

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

57

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

96

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

109

Gene therapy for chronic pain?

Gene therapy for chronic pain?

79

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

92

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

75

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

75

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

76

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

103

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

139

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

83

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

56

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

80

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

130

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

115

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

126

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

163

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

141

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

167

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

190

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

163

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

350

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

324

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

29

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

60

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

66

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

203

How cell walls guide stem cells

How cell walls guide stem cells

69

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

97

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

86

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

96

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

77

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

72

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

109

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

205

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

96

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

35

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

38

How longevity is inherited across generations

How longevity is inherited across generations

104

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

56

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

91

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

70

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

57

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

100

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

80

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

80

Gene linked with risk of delirium

Gene linked with risk of delirium

81

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

113

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

102

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

28

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

79

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

88

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

122

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

409

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

426

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

400

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

440

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

299

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

387

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

466

Role of ECM in brain memory

Role of ECM in brain memory

389

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

400

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

67

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

41

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

61

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

50

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

59

A novel inflammatory function of platelets

A novel inflammatory function of platelets

69

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

76

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

88

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

79

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

113

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

115

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

91

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

126

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

38

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

46

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

63

sncRNAs in sperm aging

sncRNAs in sperm aging

38

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

104

How reproductive organs form

How reproductive organs form

82

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

107

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

93

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

129

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

178

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

129

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

99

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

111

Mechanism of blood vessel signaling bias

Mechanism of blood vessel signaling bias

34

How flexible protein regions retain their function

How flexible protein regions retain their function

43

Complex DNA structures without hydrogen bonds

Complex DNA structures without hydrogen bonds

33

Optovolution of proteins!

Optovolution of proteins!

45

How faulty mRNA is destroyed

How faulty mRNA is destroyed

51

Vitamin B3 extends survival with NAXD deficiency

Vitamin B3 extends survival with NAXD deficiency

55

Filamentous architecture inside droplets is required for cellular function

Filamentous architecture inside droplets is requir...

47

Ribosome organization during stress!

Ribosome organization during stress!

70

Cellular mechanism behind muscle repair uncovered!

Cellular mechanism behind muscle repair uncovered!

42

How aging reshapes cells across the entire mammalian body

How aging reshapes cells across the entire mammali...

64

Keeping cells’ recycling system in balance

Keeping cells’ recycling system in balance

43

How the cells compensate for the faulty transcription?

How the cells compensate for the faulty transcript...

43

ER remodelling in ageing!

ER remodelling in ageing!

36

Enhancing gut-brain communication reversed cognitive decline in aging mice

Enhancing gut-brain communication reversed cogniti...

38

How deadly Marburg virus enters human cells

How deadly Marburg virus enters human cells

31

Microbiota derived nicotinic acid protects colon tissue

Microbiota derived nicotinic acid protects colon t...

48

Recent pandemic viruses jumped to humans without prior adaptation

Recent pandemic viruses jumped to humans without p...

29

How bacteria suppress immune defenses in stubborn wound infections

How bacteria suppress immune defenses in stubborn ...

43

Bacteria found in mouth and gut may help protect against severe peanut allergies

Bacteria found in mouth and gut may help protect a...

31

Molecular mechanism regulating bacterial cell division discovered

Molecular mechanism regulating bacterial cell divi...

46

Infant probiotic design from global microbiome atlas

Infant probiotic design from global microbiome atlas

36

Structures of hantavirus glycoprotein tetramers

Structures of hantavirus glycoprotein tetramers

43

Key protein that stops malaria parasite growth identified!

Key protein that stops malaria parasite growth ide...

44

Microbial interactions predict gut health

Microbial interactions predict gut health

46

Broad protection against many respiratory infections and allergens by a single vaccine

Broad protection against many respiratory infectio...

35

How respiratory bacterium obtains essential lipids from the host

How respiratory bacterium obtains essential lipids...

37

A developmental atlas for genes and cells

A developmental atlas for genes and cells

34

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

66

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

58

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

138

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

121

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

123

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

140

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

219

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

280

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

311

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

325

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

300

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

314

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

42

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

35

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

38

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

101

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

188

How cucumbers got longer?

How cucumbers got longer?

149

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

101

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

115

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

106

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

175

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

382

How plants sense heat during the day

How plants sense heat during the day

339

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

312

Immune cells regulate eye pressure linked to glaucoma

Immune cells regulate eye pressure linked to glaucoma

34

How the fats we eat shape our ability to fight disease

How the fats we eat shape our ability to fight dis...

47

How immune cells extract nuclear DNA from dying cells

How immune cells extract nuclear DNA from dying cells

72

How the immune system recognizes viral RNA

How the immune system recognizes viral RNA

51

How dietary restriction rewires immunity to protect against infection

How dietary restriction rewires immunity to protec...

34

How chronic inflammation rewires macrophages

How chronic inflammation rewires macrophages

108

How a common immunosuppressive drug “ATG” injures liver blood vessels

How a common immunosuppressive drug “ATG” injures ...

42

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

40

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

69

Fat surrounding the colon interacts with the immune system

Fat surrounding the colon interacts with the immun...

139

How inflammatory bowel disease promotes colorectal cancer

How inflammatory bowel disease promotes colorectal...

105

How gut pain-sensing neurons elicit immune response

How gut pain-sensing neurons elicit immune response

82

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

128

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

97

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

379

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

276

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

736

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

358

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

348

Printed skin to replace animal testing

Printed skin to replace animal testing

353

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

327

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

345

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

377

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

375

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

37

Glycoprotein heterodimers on nanoparticles for hepatitis C virus vaccine design

Glycoprotein heterodimers on nanoparticles for hep...

36

Assay to analyze regulatory function and epigenomic modifications simultaneously

Assay to analyze regulatory function and epigenomi...

43

Peptide ligase–mediated display

Peptide ligase–mediated display

33

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

39

How bacteria bind to different types of cells

How bacteria bind to different types of cells

20

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

50

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

44

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

57

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

61

‘Revoice’ device gives stroke patients their voice back

‘Revoice’ device gives stroke patients their voice...

75

Specialized transporters relay lipids to cellular targets

Specialized transporters relay lipids to cellular ...

66

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

68

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

116

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

306

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

301

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

315

How the brain regulates emotions

How the brain regulates emotions

393

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

390

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

375

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

420

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

389

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

395

Link between dietary choices and brain health

Link between dietary choices and brain health

366

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

322

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

446

Research

Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain

Cell-type-specific transposon demethylation and TA...

12

Targeting the senescence–autophagy axis for idiopathic pulmonary fibrosis therapy

Targeting the senescence–autophagy axis for idiopa...

227

Cullin–RING receptors in rare disease biology

Cullin–RING receptors in rare disease biology

22

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Pluripotent stem-cell-based screening uncovers sil...

13

Intestinal interoceptive dysfunction drives age-associated cognitive decline

Intestinal interoceptive dysfunction drives age-as...

16

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Structures of Marburgvirus glycoprotein and its co...

14

The role of nutrient stress in DNA damage

The role of nutrient stress in DNA damage

40

DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay

DCPS modulates TDP-43-linked neurodegeneration thr...

27

The Janus face of NK cells in neurodevelopment

The Janus face of NK cells in neurodevelopment

35

Ageing promotes metastasis via activation of the integrated stress response

Ageing promotes metastasis via activation of the i...

18

Dual phagocytosis-checkpoint blockade revitalizes immune surveillance in mouse models of glioblastoma

Dual phagocytosis-checkpoint blockade revitalizes ...

21

Signaling bias of the protease-activated receptor-1 is dictated by distinct GRK5 and β-arrestin-2 determinants

Signaling bias of the protease-activated receptor-...

17

A conundrum resolved: regulation and activation of UvrD-family DNA helicases/translocases

A conundrum resolved: regulation and activation of...

28

Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain

Cell-type-specific transposon demethylation and TA...

12

Targeting the senescence–autophagy axis for idiopathic pulmonary fibrosis therapy

Targeting the senescence–autophagy axis for idiopa...

227

Cullin–RING receptors in rare disease biology

Cullin–RING receptors in rare disease biology

22

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Pluripotent stem-cell-based screening uncovers sil...

13

Intestinal interoceptive dysfunction drives age-associated cognitive decline

Intestinal interoceptive dysfunction drives age-as...

16

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Structures of Marburgvirus glycoprotein and its co...

14

The role of nutrient stress in DNA damage

The role of nutrient stress in DNA damage

40

DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay

DCPS modulates TDP-43-linked neurodegeneration thr...

27

The Janus face of NK cells in neurodevelopment

The Janus face of NK cells in neurodevelopment

35

Ageing promotes metastasis via activation of the integrated stress response

Ageing promotes metastasis via activation of the i...

18

Dual phagocytosis-checkpoint blockade revitalizes immune surveillance in mouse models of glioblastoma

Dual phagocytosis-checkpoint blockade revitalizes ...

21

Signaling bias of the protease-activated receptor-1 is dictated by distinct GRK5 and β-arrestin-2 determinants

Signaling bias of the protease-activated receptor-...

17

A conundrum resolved: regulation and activation of UvrD-family DNA helicases/translocases

A conundrum resolved: regulation and activation of...

28

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

45

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

50

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Simultaneous epigenomic profiling and regulatory a...

51

Single-cell and isoform-specific translational profiling of the mouse brain

Single-cell and isoform-specific translational pro...

59

Medaka: a novel model for analyzing genome– environment interactions

Medaka: a novel model for analyzing genome– enviro...

4602

Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization

Development of human induced pluripotent stem cell...

49

Challenges and opportunities in adapting high-throughput functional assays for in vivo neuroscience

Challenges and opportunities in adapting high-thro...

63

Synthetic serum markers enable noninvasive monitoring of gene expression in primate brains

Synthetic serum markers enable noninvasive monitor...

40

Peptide ligase–mediated display: A cell-free platform for tunable selection of affinity peptides

Peptide ligase–mediated display: A cell-free platf...

2471

Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury

Brain-wide mapping of oligodendrocyte organization...

51

A unified framework combining linear and 3D molecular features for robust drug-protein interaction prediction

A unified framework combining linear and 3D molecu...

65

Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

Multi-omic analysis of guided and unguided forebra...

72

3D multiparametric ultrasound imaging of steatotic liver disease in a study with male rats

3D multiparametric ultrasound imaging of steatotic...

72

THALASSEMIA

THALASSEMIA

53

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

68

NMDA RECEPTORS

NMDA RECEPTORS

104

Neural Development

Neural Development

75

Transcription Factors

Transcription Factors

141

Interferons

68

RABIES

49

ANEMIA

38

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

58

Migraine

32

Dementia

80

Trisomy

53

Cystic Fibrosis

Cystic Fibrosis

60

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

77298

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1254

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1144

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3878

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

389

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

376

HEAD AND NECK CANCER

HEAD AND NECK CANCER

400

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

242

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

370

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

414

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

356

Gestational diabetes therapeutics

Gestational diabetes therapeutics

346

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

379

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

551

Different types of Alzheimer's disease

Different types of Alzheimer's disease

457

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

414

Alzheimer’s therapeutics

Alzheimer’s therapeutics

416

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

423

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

441

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

384

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

396

APOE in Alzheimer’s

APOE in Alzheimer’s

470

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

540

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

551

Different types of Alzheimer's disease

Different types of Alzheimer's disease

457

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

414

Alzheimer’s therapeutics

Alzheimer’s therapeutics

416

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

423

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

441

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

384

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

396

APOE in Alzheimer’s

APOE in Alzheimer’s

470

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

540

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

382

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

429

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

367

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

356

Gestational diabetes therapeutics

Gestational diabetes therapeutics

346

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

379