Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

16182

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

80

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

103

Science News Highlights

Patient-derived organoids in hematologic malignancies

News highlights

Patient-derived organoids in hematologic malignancies

11

Trade-off between maternal overnutrition and placental adaptation

News highlights

Trade-off between maternal overnutrition and placent...

8

Genotype to metabolic phenotype in microbial resistance

News highlights

Genotype to metabolic phenotype in microbial resistance

20

News

How plants sense touch?

How plants sense touch?

66

Microplastics cause fatty liver disease

Microplastics cause fatty liver disease

42

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

2514

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

309

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

54

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

84

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

38

Heredity is about more than just DNA

Heredity is about more than just DNA

38

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

86

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

387

Neck lymph node removal linked to increased risk of cognitive decline

Neck lymph node removal linked to increased risk o...

136

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

646

How the biological clock regulates phases of wakefulness

How the biological clock regulates phases of wakef...

78

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

38

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

86

Neck lymph node removal linked to increased risk of cognitive decline

Neck lymph node removal linked to increased risk o...

136

How the biological clock regulates phases of wakefulness

How the biological clock regulates phases of wakef...

78

Prion-like transmission of tau in the mouse brain

Prion-like transmission of tau in the mouse brain

57

What happens in the brain when cannabis makes you anxious?

What happens in the brain when cannabis makes you ...

72

Blocking immune cells’ path into brain limits neurodegeneration

Blocking immune cells’ path into brain limits neur...

179

Brain circuit that remembers stresses identified!

Brain circuit that remembers stresses identified!

148

Alzheimer’s disease and aging reshape brain communication in different ways

Alzheimer’s disease and aging reshape brain commun...

195

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

70

Changes in retinal dopamine balance during inherited retinal degenerations

Changes in retinal dopamine balance during inherit...

47

Genes that help flatworms regenerate their brains identified!

Genes that help flatworms regenerate their brains...

75

Linking brain injury to brain tumors

Linking brain injury to brain tumors

82

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

54

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

84

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

646

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

98

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

105

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

203

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

122

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

83

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

67

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

93

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

101

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

80

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

94

Microplastics cause fatty liver disease

Microplastics cause fatty liver disease

42

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

380

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

316

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

86

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

83

Mechanism of obesity relapse

Mechanism of obesity relapse

193

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

150

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

132

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

537

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

195

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

228

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

274

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

299

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

309

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

149

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

146

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

233

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

278

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

80

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

80

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

117

AI language models for aging biology

AI language models for aging biology

206

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

109

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

144

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

176

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

136

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

45

Protein-based data storage

Protein-based data storage

235

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

226

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

240

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

381

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

302

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

345

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

407

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

402

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

361

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

397

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

357

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

436

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

47

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

147

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

128

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

124

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

98

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

135

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

113

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

142

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

134

A novel 3D brain tissue model

A novel 3D brain tissue model

163

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

157

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

144

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

219

Heredity is about more than just DNA

Heredity is about more than just DNA

38

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

58

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

103

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

91

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

86

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

77

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

88

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

77

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

91

Generational chromosome repair!

Generational chromosome repair!

85

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

83

Is our personality written in our genes?

Is our personality written in our genes?

185

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

111

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

126

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

80

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

82

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

115

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

150

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

187

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

190

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

178

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

181

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

281

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

304

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

301

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

321

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

57

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

79

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

81

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

68

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

87

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

125

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

113

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

110

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

145

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

132

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

140

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

160

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

159

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

202

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

172

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

80

Postbiotics may boost female fertility

Postbiotics may boost female fertility

150

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

155

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

161

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

241

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

231

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

267

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

251

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

316

sncRNAs in sperm aging

sncRNAs in sperm aging

372

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

298

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

2514

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

166

New role for cohesin in DNA replication

New role for cohesin in DNA replication

132

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

72

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

115

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

58

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

73

How a protein shapes the cell membrane

How a protein shapes the cell membrane

82

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

93

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

66

How blood cells release key signaling lipid

How blood cells release key signaling lipid

84

Transcription of eight letter codon!

Transcription of eight letter codon!

91

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

93

Alternate pathway of antibiotic resistance

Alternate pathway of antibiotic resistance

48

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

36

How bacteria fight viruses

How bacteria fight viruses

55

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

1104

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

169

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

74

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

73

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

119

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

63

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

77

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

133

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

106

Methylation puts parasites in motion

Methylation puts parasites in motion

84

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

144

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

72

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

83

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

87

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

88

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

91

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

126

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

178

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

185

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

172

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

168

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

193

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

170

How plants sense touch?

How plants sense touch?

66

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

72

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

62

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

109

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

98

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

109

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

178

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

159

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

174

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

159

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

163

Cure for dry eye disease

Cure for dry eye disease

196

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

230

Sex difference in immune ageing

Sex difference in immune ageing

67

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

85

Why some people can fight infections better than others?

Why some people can fight infections better than o...

119

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

111

Gene circuits of human immunity

Gene circuits of human immunity

127

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

112

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

126

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

94

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

116

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

114

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

107

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

120

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

114

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

72

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

131

Air-permeable hydrogels!

Air-permeable hydrogels!

164

Temperature behaves differently in the cell

Temperature behaves differently in the cell

163

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

144

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

191

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

218

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

299

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

568

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

464

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

950

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

561

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

560

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

387

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

46

A world-first DNA computer

A world-first DNA computer

50

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

94

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

66

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

100

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

70

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

103

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

108

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

86

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

104

Viral RNA elements functional map!

Viral RNA elements functional map!

99

How proteins change shape and move

How proteins change shape and move

104

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

178

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

321

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

505

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

531

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

493

How the brain regulates emotions

How the brain regulates emotions

720

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

584

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

589

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

590

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

564

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

557

Link between dietary choices and brain health

Link between dietary choices and brain health

526

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

522

Research

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

170

Patient-derived organoids in hematologic malignancies: Fidelity and translation beyond animals

Patient-derived organoids in hematologic malignanc...

17

A sequential MAP kinase cascade regulates mechanical signalling

A sequential MAP kinase cascade regulates mechanic...

39

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Size-dependent plastic exposure disrupts macrophag...

24

Leveraging high-throughput proteomics and AI-based protein folding to accelerate VAV1 molecular glue discovery

Leveraging high-throughput proteomics and AI-based...

22

Placental adaptation to maternal overnutrition as an evolutionary trade-off

Placental adaptation to maternal overnutrition as ...

25

UHRF1 overexpression generates distinct senescent states with different Tp53 dependencies

UHRF1 overexpression generates distinct senescent ...

22

Sensing a problem here: nucleotide signaling in immunity

Sensing a problem here: nucleotide signaling in im...

30

Microbial resistance from genotype to metabolic phenotype

Microbial resistance from genotype to metabolic ph...

37

Bias from within: intracellular allosterism and the ICL2 hub

Bias from within: intracellular allosterism and th...

36

Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancer

Spatial evolution of a cachexia-promoting microenv...

18

Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing

Complementary roles of cell-type-specific plastici...

67

Transgenerational inheritance of altered H3K27me3 in wild-type Caenorhabditis elegans

Transgenerational inheritance of altered H3K27me3 ...

27

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

170

Patient-derived organoids in hematologic malignancies: Fidelity and translation beyond animals

Patient-derived organoids in hematologic malignanc...

17

A sequential MAP kinase cascade regulates mechanical signalling

A sequential MAP kinase cascade regulates mechanic...

39

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Size-dependent plastic exposure disrupts macrophag...

24

Leveraging high-throughput proteomics and AI-based protein folding to accelerate VAV1 molecular glue discovery

Leveraging high-throughput proteomics and AI-based...

22

Placental adaptation to maternal overnutrition as an evolutionary trade-off

Placental adaptation to maternal overnutrition as ...

25

UHRF1 overexpression generates distinct senescent states with different Tp53 dependencies

UHRF1 overexpression generates distinct senescent ...

22

Sensing a problem here: nucleotide signaling in immunity

Sensing a problem here: nucleotide signaling in im...

30

Microbial resistance from genotype to metabolic phenotype

Microbial resistance from genotype to metabolic ph...

37

Bias from within: intracellular allosterism and the ICL2 hub

Bias from within: intracellular allosterism and th...

36

Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancer

Spatial evolution of a cachexia-promoting microenv...

18

Complementary roles of cell-type-specific plasticity in shaping neocortical dynamics for learning action timing

Complementary roles of cell-type-specific plastici...

67

Transgenerational inheritance of altered H3K27me3 in wild-type Caenorhabditis elegans

Transgenerational inheritance of altered H3K27me3 ...

27

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

58

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

47

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

82

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

90

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

110

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

193

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

100

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

84

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

71

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

66

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

65

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

65

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

95

Breeding of Cotton

Breeding of Cotton

738

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

974

THALASSEMIA

THALASSEMIA

1076

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

1074

NMDA RECEPTORS

488

Neural Development

Neural Development

475

Transcription Factors

Transcription Factors

464

Interferons

415

RABIES

426

ANEMIA

439

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

414

Migraine

346

Dementia

435

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

36

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

49

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

61

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

7075

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

54

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

73

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

2953

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

113

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

112

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

90

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2382

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

56

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

108

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

548

Gestational diabetes therapeutics

Gestational diabetes therapeutics

643

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

592

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

938

Different types of Alzheimer's disease

Different types of Alzheimer's disease

693

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

625

Alzheimer’s therapeutics

Alzheimer’s therapeutics

779

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

667

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

669

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

608

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

604

APOE in Alzheimer’s

APOE in Alzheimer’s

835

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

760

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

938

Different types of Alzheimer's disease

Different types of Alzheimer's disease

693

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

625

Alzheimer’s therapeutics

Alzheimer’s therapeutics

779

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

667

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

669

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

608

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

604

APOE in Alzheimer’s

APOE in Alzheimer’s

835

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

760

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

581

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

771

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

555

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

548

Gestational diabetes therapeutics

Gestational diabetes therapeutics

643

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

592