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All Publications Protocols Presentations Posters
An amygdala to anterior hypothalamic circuit gates stress sensitivity

An amygdala to anterior hypothalamic circuit ...

 13

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and cla...

 16

Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC

Endurance exercise elicits temporal and sexua...

 16

Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen

Mitochondrial proteome of Acanthamoeba deline...

 18

An amygdala to anterior hypothalamic circuit gates stress sensitivity

An amygdala to anterior hypothalamic circuit ...

 13

Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC

Endurance exercise elicits temporal and sexua...

 16

Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen

Mitochondrial proteome of Acanthamoeba deline...

 18

Sound asleep, yet still listening: auditory processing during human sleep

Sound asleep, yet still listening: auditory p...

 26

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and cla...

 16

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innova...

 20

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 26

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

 63

Breeding of Cotton

Breeding of Cotton

 713

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 927

THALASSEMIA

THALASSEMIA

 1046

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1043

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrang...

 2843

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants ...

 45

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the AP...

 56

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patie...

 2943

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Science Hangouts

Dimerization and activation of receptor tyrosine kinases:  insights from quantitative fluorescence studies
Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

 15867

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty
Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

 68

Systems Biology & Medicine: Markers, Mechanisms and Pathways
Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

 80

Science News Highlights

How does brain listen during human sleep?
News highlights

How does brain listen during human sleep?

 14

Quantum computing for biotechnological innovation
News highlights

Quantum computing for biotechnological innovation

 15

How to track newly synthesised proteins in plants
News highlights

How to track newly synthesised proteins in plants

 16

News

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Brain circuit that remembers stresses identified!

Brain circuit that remembers stresses identified!

 34

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

 16

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

 78

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

 22

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

 29

Sex difference in immune ageing

Sex difference in immune ageing

 31

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

 150

Alzheimer’s disease and aging reshape brain communication in different ways

Alzheimer’s disease and aging reshape brain commun...

 150

How bacteria fight viruses

How bacteria fight viruses

 31

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

 31

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

 54

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

 143

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

 43

Brain circuit that remembers stresses identified!

Brain circuit that remembers stresses identified!

 34

Alzheimer’s disease and aging reshape brain communication in different ways

Alzheimer’s disease and aging reshape brain commun...

 150

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

 43

Changes in retinal dopamine balance during inherited retinal degenerations

Changes in retinal dopamine balance during inherit...

 32

 Genes that help flatworms regenerate their brains identified!

 Genes that help flatworms regenerate their brains...

 50

Linking brain injury to brain tumors

Linking brain injury to brain tumors

 65

Why do we stay afraid for so long when the brain’s first alarm fires so fast?

Why do we stay afraid for so long when the brain’s...

 54

Molecular mechanism of short-term synaptic plasticity was discovered

Molecular mechanism of short-term synaptic plastic...

 54

A hidden brain region coordinates metabolic adaptations to cold

A hidden brain region coordinates metabolic adapta...

 84

Retinotopic remapping of the visual system in deaf adults

Retinotopic remapping of the visual system in deaf...

 57

How Alzheimer’s risk factor, APOE4, damages blood vessels?

How Alzheimer’s risk factor, APOE4, damages blood ...

 132

Neuroprosthesis for paralysis enables simultaneous speech and body language

Neuroprosthesis for paralysis enables simultaneous...

 257

Brain activity can predict a risky decision before it’s made

Brain activity can predict a risky decision before...

 99

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

 54

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

 88

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

 114

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

 112

Cancer-linked protein binds to chromosome in unexpected way 

Cancer-linked protein binds to chromosome in unexp...

 77

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

 60

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

 83

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

 92

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

 71

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

 85

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

 104

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

 109

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

 125

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

 78

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

 150

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

 56

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

 76

Mechanism of obesity relapse

Mechanism of obesity relapse

 183

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

 140

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

 122

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

 527

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

 188

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

 216

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

 262

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

 291

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

 277

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

 128

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

 207

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

 216

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

 72

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

 72

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

 108

AI language models for aging biology

AI language models for aging biology

 196

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

 99

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

 135

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

 163

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

 123

Proteomic signatures in children blood may provide clues to  cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

 89

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

 239

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

 33

Protein-based data storage

Protein-based data storage

 228

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

 218

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

 230

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

 375

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

 294

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

 337

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 396

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 387

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 352

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 391

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 350

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 425

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

 116

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

 119

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

 115

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

 90

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

 129

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

 108

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

 130

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

 127

A novel 3D brain tissue model

A novel 3D brain tissue model

 157

EV  secretome to treat cardiac fibrosis

EV  secretome to treat cardiac fibrosis

 146

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

 136

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

 213

Reverting aged cells to stem cells

Reverting aged cells to stem cells

 280

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

 22

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

 31

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

 79

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

 73

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

 71

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

 82

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

 67

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

 80

Generational chromosome repair!

Generational chromosome repair!

 76

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

 74

Is our personality written in our genes?

Is our personality written in our genes?

 179

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

 98

How chromosomes find their partners

How chromosomes find their partners

 170

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

 93

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

 68

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

 75

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

 107

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

 145

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

 179

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

 182

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

 170

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

 174

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

 274

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

 299

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

 293

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

 315

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

 29

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

 64

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

 71

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

 60

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

 80

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

 113

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

 107

Capillaries and not arteries give rise to  backup blood vessels

Capillaries and not arteries give rise to backup ...

 103

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

 134

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

 124

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

 131

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

 155

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

 152

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

 164

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

 165

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

 74

Postbiotics may boost female fertility

Postbiotics may boost female fertility

 144

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

 150

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

 151

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

 229

Aging human breast atlas reveals  cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

 222

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

 259

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

 244

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

 308

sncRNAs in sperm aging

sncRNAs in sperm aging

 361

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

 291

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

 143

New role for cohesin in DNA replication

New role for cohesin in DNA replication

 92

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

 59

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

 105

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

 52

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

 67

How a protein shapes the cell membrane

How a protein shapes the cell membrane

 73

 Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

 Structural basis of metabotropic glutamate recept...

 88

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

 61

How blood cells release key signaling lipid

How blood cells release key signaling lipid

 75

Transcription of eight letter codon!

Transcription of eight letter codon!

 86

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

 88

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

 74

How bacteria fight viruses

How bacteria fight viruses

 31

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

 993

 How Epstein-Barr Virus triggers multiple sclerosis relapse

 How Epstein-Barr Virus triggers multiple sclerosi...

 145

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

 70

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

 69

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

 113

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

 56

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

 71

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

 124

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

 102

Methylation puts parasites in motion

Methylation puts parasites in motion

 81

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

 183

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

 223

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

 131

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

 68

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

 77

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

 81

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

 83

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

 87

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

 121

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

 172

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

 179

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

 166

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

 159

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

 189

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

 167

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

 65

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

 56

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

 97

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

 93

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

 104

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

 174

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

 153

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

 164

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

 152

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

 157

Cure for dry eye disease

Cure for dry eye disease

 190

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

 214

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

 212

Sex difference in immune ageing

Sex difference in immune ageing

 31

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

 50

Why some people can fight infections better than others?

Why some people can fight infections better than o...

 115

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

 105

Gene circuits of human immunity

Gene circuits of human immunity

 120

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

 109

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

 122

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

 89

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 111

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

 108

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

 103

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

 113

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

 108

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

 60

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

 118

Air-permeable hydrogels!

Air-permeable hydrogels!

 157

Temperature behaves differently in the cell

Temperature behaves differently in the cell

 156

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

 138

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

 186

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

 213

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

 283

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 562

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 457

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 945

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 553

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 544

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

 16

A world-first DNA computer 

A world-first DNA computer 

 44

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

 77

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

 61

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

 93

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

 62

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

 99

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

 103

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

 83

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

 99

Viral RNA elements functional map!

Viral RNA elements functional map!

 90

How proteins change shape and move

How proteins change shape and move

 100

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

 106

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

 170

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 314

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 501

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 527

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 485

How the brain regulates emotions

How the brain regulates emotions

 716

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 573

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 579

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 587

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 559

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 553

Link between dietary choices and brain health

Link between dietary choices and brain health

 523

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 517

Research

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An amygdala to anterior hypothalamic circuit gates stress sensitivity

An amygdala to anterior hypothalamic circuit gates...

 13

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

 16

Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC

Endurance exercise elicits temporal and sexual dim...

 16

Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen

Mitochondrial proteome of Acanthamoeba delineates ...

 18

Sound asleep, yet still listening: auditory processing during human sleep

Sound asleep, yet still listening: auditory proces...

 26

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

 20

Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type

Hypoxia-activated scleraxis a mediates epicardial ...

 18

Sex-specific trajectories of nonlinear immune aging at single-cell level

Sex-specific trajectories of nonlinear immune agin...

 17

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 26

The tumor macroenvironment as cancer metabolism’s next frontier

The tumor macroenvironment as cancer metabolism’s ...

 43

Different functional connectivity gradients reflect aging and Alzheimer’s disease

Different functional connectivity gradients reflec...

 38

Phage protease enzymes activate CBASS antiphage immunity

Phage protease enzymes activate CBASS antiphage im...

 25

MAIT cells in gastrointestinal cancer: immunity to therapy

MAIT cells in gastrointestinal cancer: immunity to...

 27

An amygdala to anterior hypothalamic circuit gates stress sensitivity

An amygdala to anterior hypothalamic circuit gates...

 13

Endurance exercise elicits temporal and sexual dimorphic multi-omics remodeling of liver metabolism revealed by MoTrPAC

Endurance exercise elicits temporal and sexual dim...

 16

Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen

Mitochondrial proteome of Acanthamoeba delineates ...

 18

Sound asleep, yet still listening: auditory processing during human sleep

Sound asleep, yet still listening: auditory proces...

 26

Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type

Hypoxia-activated scleraxis a mediates epicardial ...

 18

Sex-specific trajectories of nonlinear immune aging at single-cell level

Sex-specific trajectories of nonlinear immune agin...

 17

The tumor macroenvironment as cancer metabolism’s next frontier

The tumor macroenvironment as cancer metabolism’s ...

 43

Different functional connectivity gradients reflect aging and Alzheimer’s disease

Different functional connectivity gradients reflec...

 38

Phage protease enzymes activate CBASS antiphage immunity

Phage protease enzymes activate CBASS antiphage im...

 25

MAIT cells in gastrointestinal cancer: immunity to therapy

MAIT cells in gastrointestinal cancer: immunity to...

 27

The immunoregulatory role of progesterone during embryo implantation and pregnancy

The immunoregulatory role of progesterone during e...

 28

Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity

Sensory neuronal mTORC1 kinase signaling establish...

 54

Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa

Altered Retinal Dopamine Homeostasis in Murine Mod...

 27

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

 16

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

 20

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 26

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

 63

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

 103

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

 184

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

 94

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

 79

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

 66

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

 62

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

 60

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

 61

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

 91

Breeding of Cotton

Breeding of Cotton

 713

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 927

THALASSEMIA

THALASSEMIA

 1046

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1043

NMDA RECEPTORS

NMDA RECEPTORS

 485

Neural Development

Neural Development

 470

Transcription Factors

Transcription Factors

 459

Interferons

Interferons

 411

RABIES

RABIES

 422

ANEMIA

ANEMIA

 433

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

 409

Migraine

Migraine

 339

Dementia

Dementia

 430

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

 2843

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

 45

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

 56

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

 2943

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

 103

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

 103

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

 83

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

 2376

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

 52

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

 104

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

 753

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

 96

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

 142

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 542

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 635

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 588

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 930

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 683

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 618

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 766

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 650

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 658

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 597

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 592

APOE in Alzheimer’s

APOE in Alzheimer’s

 823

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 749

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 930

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 683

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 618

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 766

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 650

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 658

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 597

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 592

APOE in Alzheimer’s

APOE in Alzheimer’s

 823

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 749

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 578

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 757

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 545

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 542

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 635

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 588

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