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All Publications Protocols Presentations Posters
Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phen...

 12

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling dr...

 23

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and ar...

 30

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines ...

 25

Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phen...

 12

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling dr...

 23

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and ar...

 30

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines ...

 25

Comprehensive benchmarking of somatic mutation detection by the SMaHT Network

Comprehensive benchmarking of somatic mutatio...

 65

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular ph...

 203

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex i...

 92

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial ...

 165

Breeding of Cotton

Breeding of Cotton

 807

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 1082

THALASSEMIA

THALASSEMIA

 1152

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1164

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurol...

 104

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for canc...

 128

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-F...

 150

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrang...

 13473

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Science Hangouts

Dimerization and activation of receptor tyrosine kinases:  insights from quantitative fluorescence studies
Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

 16729

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty
Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

 118

Systems Biology & Medicine: Markers, Mechanisms and Pathways
Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

 136

Novel Anti-inflammatory Bioactive Lipids from the CYP epoxygenase Pathway
Science Hangouts

Novel Anti-inflammatory Bioactive Lipids from the CYP epoxygenase Pathway

 32

Science News Highlights

The recipe for intelligence in natural and artificial systems
News highlights

The recipe for intelligence in natural and artificial systems

 12

 Structure of Mg2+ transport protein, CNNM4 unraveled!
News highlights

 Structure of Mg2+ transport protein, CNNM4 unraveled!

 12

What is cancer cartography?
News highlights

What is cancer cartography?

 20

News

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AI based study demonstrates stimulation of brown fat by blood-pressure drug

AI based study demonstrates stimulation of brown f...

 15

Activating just 20 neurons trigger learned movements 

Activating just 20 neurons trigger learned movements 

 9

AI identifies a regulator of aging

AI identifies a regulator of aging

 616

Breast milk antibodies show broad antiviral activity and protect mice against influenza

Breast milk antibodies show broad antiviral activi...

 40

Skin stem cell renewal shows sexual dimorphism

Skin stem cell renewal shows sexual dimorphism

 205

Mammals produce cyclo-octasulfur to protect cells from lipid damage

Mammals produce cyclo-octasulfur to protect cells ...

 140

Nerve and immune cells interact to fuel pain in endometriosis

Nerve and immune cells interact to fuel pain in en...

 143

Alcohol and the brain interact through immune cells

Alcohol and the brain interact through immune cells

 172

Achilles' heel of antibiotic-resistant bacteria discovered

Achilles' heel of antibiotic-resistant bacteria di...

 298

The shape of water defines the hotspot that starts protein aggregation in dementia

The shape of water defines the hotspot that starts...

 105

Treating depression during pregnancy may benefit babies' brain development

Treating depression during pregnancy may benefit b...

 42

Secreted phospholipase confers neuroprotection and cognitive resilience during aging

Secreted phospholipase confers neuroprotection and...

 47

New mechanism for Candida auris to resist antifungal treatment

New mechanism for Candida auris to resist antifung...

 143

Activating just 20 neurons trigger learned movements 

Activating just 20 neurons trigger learned movements 

 9

Alcohol and the brain interact through immune cells

Alcohol and the brain interact through immune cells

 172

Treating depression during pregnancy may benefit babies' brain development

Treating depression during pregnancy may benefit b...

 42

Secreted phospholipase confers neuroprotection and cognitive resilience during aging

Secreted phospholipase confers neuroprotection and...

 47

Opioid painkiller platform to turn ‘on’ or ‘off’ with light

Opioid painkiller platform to turn ‘on’ or ‘off’ w...

 62

How critical brain cells misfire in Alzheimer's

How critical brain cells misfire in Alzheimer's

 707

Capsaicin receptor, TRPV1, responds differently to varying triggers

Capsaicin receptor, TRPV1, responds differently to...

 246

Reducing pathological pain!

Reducing pathological pain!

 72

Effect of processed food on brain metabolism and function

Effect of processed food on brain metabolism and f...

 100

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

 111

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

 114

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

 84

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

 147

Exposure to common chemicals alter normal breast development

Exposure to common chemicals alter normal breast d...

 74

Cigarette smoke may prime lung stem cells for different types of lung cancer

Cigarette smoke may prime lung stem cells for diff...

 92

Regulating cellular recycling

Regulating cellular recycling

 79

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

 89

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

 137

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

 699

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

 130

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

 137

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

 241

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

 148

Cancer-linked protein binds to chromosome in unexpected way 

Cancer-linked protein binds to chromosome in unexp...

 116

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

 93

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

 130

Hitting two organs with one common signaling regulator

Hitting two organs with one common signaling regul...

 446

Microplastics cause fatty liver disease 

Microplastics cause fatty liver disease 

 108

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

 459

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

 379

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

 124

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

 107

Mechanism of obesity relapse

Mechanism of obesity relapse

 221

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

 181

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

 159

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

 562

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

 224

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

 256

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

 315

AI identifies a regulator of aging

AI identifies a regulator of aging

 616

AI tool for designing biomolecules with atomic precision

AI tool for designing biomolecules with atomic pre...

 1495

AI tool identifies new dimension of biological variability in the genome

AI tool identifies new dimension of biological var...

 54

AI language models that see every letter

AI language models that see every letter

 86

Mapping cellular gene functions with AI and microscopy

Mapping cellular gene functions with AI and micros...

 71

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

 94

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

 639

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

 190

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

 174

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

 275

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

 321

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

 113

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

 109

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

 73

Protein-based data storage

Protein-based data storage

 263

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

 255

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

 270

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

 416

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

 326

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

 371

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 439

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 429

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 386

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 422

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 383

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 460

Skin stem cell renewal shows sexual dimorphism

Skin stem cell renewal shows sexual dimorphism

 205

Signal timing determines cell type balance in the gut

Signal timing determines cell type balance in the gut

 270

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

 103

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

 189

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

 155

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

 157

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

 126

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

 160

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

 142

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

 164

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

 168

A novel 3D brain tissue model

A novel 3D brain tissue model

 189

EV  secretome to treat cardiac fibrosis

EV  secretome to treat cardiac fibrosis

 193

Detecting DNA mutations across the human genome

Detecting DNA mutations across the human genome

 136

Genetic differences between humans and chimpanzees

Genetic differences between humans and chimpanzees

 282

Heredity is about more than just DNA

Heredity is about more than just DNA

 115

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

 98

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

 185

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

 117

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

 113

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

 103

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

 113

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

 104

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

 118

Generational chromosome repair!

Generational chromosome repair!

 116

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

 107

Why exercise is good for us?

Why exercise is good for us?

 89

How cellular self-organization steers and stops waves of cell death

How cellular self-organization steers and stops wa...

 66

Controlling aging muscle

Controlling aging muscle

 565

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

 155

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

 113

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

 112

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

 138

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

 173

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

 216

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

 220

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

 207

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

 205

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

 312

AI based study demonstrates stimulation of brown fat by blood-pressure drug

AI based study demonstrates stimulation of brown f...

 15

Linking cardiac failure to inflammatory reprogramming by bone marrow cells

Linking cardiac failure to inflammatory reprogramm...

 72

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

 86

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

 112

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

 110

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

 91

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

 111

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

 166

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

 140

Capillaries and not arteries give rise to  backup blood vessels

Capillaries and not arteries give rise to backup ...

 133

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

 172

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

 160

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

 166

Nerve and immune cells interact to fuel pain in endometriosis

Nerve and immune cells interact to fuel pain in en...

 143

Nicotine exposure during pregnancy increases flu severity later in life

Nicotine exposure during pregnancy increases flu s...

 75

Antifungal treatments during pregnancy linked to changes in foetal hormone production

Antifungal treatments during pregnancy linked to c...

 46

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

 237

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

 200

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

 103

Postbiotics may boost female fertility

Postbiotics may boost female fertility

 177

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

 177

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

 186

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

 281

Aging human breast atlas reveals  cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

 259

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

 290

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

 281

Mammals produce cyclo-octasulfur to protect cells from lipid damage

Mammals produce cyclo-octasulfur to protect cells ...

 140

The shape of water defines the hotspot that starts protein aggregation in dementia

The shape of water defines the hotspot that starts...

 105

How a protein complex guards the entrance to channels in mitochondrial membrane cristae

How a protein complex guards the entrance to chann...

 67

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

 254

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

 87

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

 3727

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

 190

New role for cohesin in DNA replication

New role for cohesin in DNA replication

 162

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

 96

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

 141

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

 79

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

 93

How a protein shapes the cell membrane

How a protein shapes the cell membrane

 100

Achilles' heel of antibiotic-resistant bacteria discovered

Achilles' heel of antibiotic-resistant bacteria di...

 298

New mechanism for Candida auris to resist antifungal treatment

New mechanism for Candida auris to resist antifung...

 143

How a bacteria senses iron?

How a bacteria senses iron?

 96

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

 660

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

 65

Alternate pathway of antibiotic resistance 

Alternate pathway of antibiotic resistance 

 76

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

 63

How bacteria fight viruses

How bacteria fight viruses

 79

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

 1142

 How Epstein-Barr Virus triggers multiple sclerosis relapse

 How Epstein-Barr Virus triggers multiple sclerosi...

 203

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

 96

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

 96

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

 136

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

 108

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

 162

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

 94

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

 100

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

 106

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

 111

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

 111

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

 145

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

 203

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

 206

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

 191

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

 187

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

 216

How plants read fungal warning signs

How plants read fungal warning signs

 186

How plant enzymes learned to tell mirror-image molecules apart

How plant enzymes learned to tell mirror-image mol...

 255

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

 67

How plants sense touch?

How plants sense touch?

 150

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

 93

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

 91

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

 131

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

 118

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

 136

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

 198

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

 180

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

 199

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

 184

Breast milk antibodies show broad antiviral activity and protect mice against influenza

Breast milk antibodies show broad antiviral activi...

 40

Sex difference in immune ageing

Sex difference in immune ageing

 120

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

 116

Why some people can fight infections better than others?

Why some people can fight infections better than o...

 143

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

 138

Gene circuits of human immunity

Gene circuits of human immunity

 153

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

 134

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

 149

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

 112

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 133

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

 131

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

 130

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

 142

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

 102

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

 163

Air-permeable hydrogels!

Air-permeable hydrogels!

 186

Temperature behaves differently in the cell

Temperature behaves differently in the cell

 180

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

 166

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

 214

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

 236

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

 323

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 586

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 487

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 980

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 577

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 595

Less invasive approach to diagnosing mitochondrial disease 

Less invasive approach to diagnosing mitochondrial...

 70

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

 547

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

 65

A world-first DNA computer 

A world-first DNA computer 

 66

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

 121

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

 96

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

 124

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

 92

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

 122

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

 126

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

 104

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

 119

Viral RNA elements functional map!

Viral RNA elements functional map!

 118

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

 201

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 343

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 527

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 553

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 516

How the brain regulates emotions

How the brain regulates emotions

 740

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 610

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 623

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 608

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 587

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 578

Link between dietary choices and brain health

Link between dietary choices and brain health

 544

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 538

Research

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    • All
    • Publications
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    • Posters
Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phenotypi...

 12

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling drives ...

 23

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and artific...

 30

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines Mg2+ ...

 25

Polyclonal breast milk–derived secretory IgA confers broad antiviral protection against multiple respiratory viruses

Polyclonal breast milk–derived secretory IgA confe...

 677

Sexual dimorphism in epidermal stem cell dynamics

Sexual dimorphism in epidermal stem cell dynamics

 25

High-resolution spatial transcriptomics reveals fibroblast and neuroimmune microenvironments in endometriosis lesions

High-resolution spatial transcriptomics reveals fi...

 20

Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse

Microglia-mediated extracellular matrix disruption...

 28

Statin-induced lipid carrier stress reveals a conserved vulnerability in β-lactam-resistant Gram-positive bacteria

Statin-induced lipid carrier stress reveals a cons...

 30

A water-pinning hot spot drives templated tau aggregation

A water-pinning hot spot drives templated tau aggr...

 805

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression

Infant hippocampal and amygdala volume in an obser...

 36

Navigating clinical decisions through cancer cartography

Navigating clinical decisions through cancer carto...

 37

Mitochondrial transfer in endothelial cells and vascular health

Mitochondrial transfer in endothelial cells and va...

 70

Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phenotypi...

 12

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling drives ...

 23

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and artific...

 30

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines Mg2+ ...

 25

Polyclonal breast milk–derived secretory IgA confers broad antiviral protection against multiple respiratory viruses

Polyclonal breast milk–derived secretory IgA confe...

 677

Sexual dimorphism in epidermal stem cell dynamics

Sexual dimorphism in epidermal stem cell dynamics

 25

High-resolution spatial transcriptomics reveals fibroblast and neuroimmune microenvironments in endometriosis lesions

High-resolution spatial transcriptomics reveals fi...

 20

Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse

Microglia-mediated extracellular matrix disruption...

 28

Statin-induced lipid carrier stress reveals a conserved vulnerability in β-lactam-resistant Gram-positive bacteria

Statin-induced lipid carrier stress reveals a cons...

 30

A water-pinning hot spot drives templated tau aggregation

A water-pinning hot spot drives templated tau aggr...

 805

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression

Infant hippocampal and amygdala volume in an obser...

 36

Navigating clinical decisions through cancer cartography

Navigating clinical decisions through cancer carto...

 37

Mitochondrial transfer in endothelial cells and vascular health

Mitochondrial transfer in endothelial cells and va...

 70

Comprehensive benchmarking of somatic mutation detection by the SMaHT Network

Comprehensive benchmarking of somatic mutation det...

 65

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular phenoty...

 203

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex image-...

 92

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

 165

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

 80

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

 93

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

 80

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 115

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

 112

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

 134

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

 214

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

 121

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

 102

Breeding of Cotton

Breeding of Cotton

 807

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 1082

THALASSEMIA

THALASSEMIA

 1152

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1164

NMDA RECEPTORS

NMDA RECEPTORS

 508

Neural Development

Neural Development

 496

Transcription Factors

Transcription Factors

 489

Interferons

Interferons

 431

RABIES

RABIES

 453

ANEMIA

ANEMIA

 464

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

 436

Migraine

Migraine

 364

Dementia

Dementia

 462

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

 104

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

 128

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

 150

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

 13473

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

 78

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

 98

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

 2991

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

 150

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

 133

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

 108

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

 2403

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

 76

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

 126

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 561

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 657

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 607

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 953

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 712

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 639

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 806

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 691

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 696

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 633

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 631

APOE in Alzheimer’s

APOE in Alzheimer’s

 863

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 786

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 953

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 712

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 639

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 806

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 691

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 696

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 633

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 631

APOE in Alzheimer’s

APOE in Alzheimer’s

 863

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 786

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 593

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 800

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 586

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 561

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 657

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 607

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