Index - Sciencemission

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

59

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

Science Hangouts

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

57

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

1217

Dynamic Memory

Science Hangouts

Dynamic Memory

51

Science News Highlights

Astrocyte-microglia crosstalk in thalamocortical synapse refinement

News highlights

Astrocyte-microglia crosstalk in thalamocortical synapse refinement

5

MitoTracker transfers from astrocytes to neurons without the mitochondria

News highlights

MitoTracker transfers from astrocytes to neurons witho...

6

Mechanism of autoimmune tissue inflammation in rheumatoid arthritis

News highlights

Mechanism of autoimmune tissue inflammation in rheumat...

7

News

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

8

How flexible protein regions retain their function

How flexible protein regions retain their function

14

High-altitude survival gene may help reverse nerve damage

High-altitude survival gene may help reverse nerve...

17

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

13

How bacteria suppress immune defenses in stubborn wound infections

How bacteria suppress immune defenses in stubborn ...

20

Cell-type specific TDP-43 pathology in the motor cortex

Cell-type specific TDP-43 pathology in the motor c...

24

A developmental atlas for genes and cells

A developmental atlas for genes and cells

21

Src kinase on the cell surface in cancer

Src kinase on the cell surface in cancer

38

Pathway controlling forelimb movement identified!

Pathway controlling forelimb movement identified!

73

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

25

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

25

Bacteria found in mouth and gut may help protect against severe peanut allergies

Bacteria found in mouth and gut may help protect a...

19

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

26

High-altitude survival gene may help reverse nerve damage

High-altitude survival gene may help reverse nerve...

17

Cell-type specific TDP-43 pathology in the motor cortex

Cell-type specific TDP-43 pathology in the motor c...

24

Pathway controlling forelimb movement identified!

Pathway controlling forelimb movement identified!

73

Oligodendrocyte molecular perturbations associated with tau in Alzheimer’s

Oligodendrocyte molecular perturbations associated...

53

Potassium channels functionality is coupled to trafficking!

Potassium channels functionality is coupled to tra...

31

Tubulin prevents toxic protein clump formation

Tubulin prevents toxic protein clump formation

49

New cellular immunotherapy approach for Alzheimer’s disease

New cellular immunotherapy approach for Alzheimer’...

66

Learning makes brain cells work together, not apart

Learning makes brain cells work together, not apart

30

How ketogenic diets prevent seizures

How ketogenic diets prevent seizures

64

A new mechanism for motor-learning circuit rewiring

A new mechanism for motor-learning circuit rewiring

46

Mapping protein production in brain cells

Mapping protein production in brain cells

63

How exercise protects the brain

How exercise protects the brain

65

How the brain suppresses itch during stress

How the brain suppresses itch during stress

58

Src kinase on the cell surface in cancer

Src kinase on the cell surface in cancer

38

Ketone supplementation improves immunotherapy

Ketone supplementation improves immunotherapy

44

Providing T cells with a sugar source to fight solid tumors

Providing T cells with a sugar source to fight sol...

46

Cancer stress protein helps tumors hide from immunity

Cancer stress protein helps tumors hide from immunity

51

Pancreatic tumor cells regulate autophagy by sensing ECM

Pancreatic tumor cells regulate autophagy by sensi...

51

Virus-based therapy boosts anti-cancer immune responses to brain cancer

Virus-based therapy boosts anti-cancer immune resp...

52

Identifying aggressive prostate cancer with multi-omics

Identifying aggressive prostate cancer with multi-...

62

Radiotherapy is more effective when administered at the right time of day

Radiotherapy is more effective when administered a...

47

Chronic cellular stress promotes liver cancer but also enhances immunotherapy efficiency

Chronic cellular stress promotes liver cancer but ...

65

How extra cellular matrix boosts triple negative breast cancer’s ability to metastasize

How extra cellular matrix boosts triple negative b...

59

How microRNA regulates intratumoral heterogeneity

How microRNA regulates intratumoral heterogeneity

65

What causes human cancers?

What causes human cancers?

105

Small number of ‘highly plastic’ cancer cells drive disease progression and treatment resistance

Small number of ‘highly plastic’ cancer cells driv...

53

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

26

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

116

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

35

Human islet cell electrical maturation

Human islet cell electrical maturation

43

Red blood cells soak up sugar at high altitude, protecting against diabetes

Red blood cells soak up sugar at high altitude, pr...

76

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

73

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

93

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

66

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

90

Exposure to natural light improves metabolic health

Exposure to natural light improves metabolic health

120

Gut microbial bileacids in infancy may influence the risk of type 1 diabetes

Gut microbial bileacids in infancy may influence t...

72

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

69

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

189

Artificial intelligence decodes tissue characteristics of type 2 diabetes

Artificial intelligence decodes tissue characteris...

29

Rapid Evolution of Complex Multi-mutant Proteins

Rapid Evolution of Complex Multi-mutant Proteins

57

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

66

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

49

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

87

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

101

Gene therapy for chronic pain?

Gene therapy for chronic pain?

73

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

84

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

68

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

70

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

70

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

97

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

134

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

76

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

49

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

75

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

123

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

108

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

122

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

158

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

134

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

163

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

185

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

159

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

342

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

320

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

52

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

62

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

196

How cell walls guide stem cells

How cell walls guide stem cells

64

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

91

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

79

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

91

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

70

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

66

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

104

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

199

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

87

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

105

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

33

How longevity is inherited across generations

How longevity is inherited across generations

97

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

51

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

82

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

64

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

52

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

93

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

75

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

74

Gene linked with risk of delirium

Gene linked with risk of delirium

74

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

106

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

99

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

122

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

8

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

72

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

81

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

118

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

405

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

419

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

394

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

436

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

293

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

384

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

460

Role of ECM in brain memory

Role of ECM in brain memory

384

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

397

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

53

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

34

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

54

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

44

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

52

A novel inflammatory function of platelets

A novel inflammatory function of platelets

63

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

69

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

81

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

72

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

108

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

108

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

85

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

120

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

25

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

39

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

54

sncRNAs in sperm aging

sncRNAs in sperm aging

33

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

95

How reproductive organs form

How reproductive organs form

75

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

102

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

89

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

124

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

172

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

123

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

94

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

107

How flexible protein regions retain their function

How flexible protein regions retain their function

14

Complex DNA structures without hydrogen bonds

Complex DNA structures without hydrogen bonds

24

Optovolution of proteins!

Optovolution of proteins!

38

How faulty mRNA is destroyed

How faulty mRNA is destroyed

42

Vitamin B3 extends survival with NAXD deficiency

Vitamin B3 extends survival with NAXD deficiency

43

Filamentous architecture inside droplets is required for cellular function

Filamentous architecture inside droplets is requir...

37

Ribosome organization during stress!

Ribosome organization during stress!

62

Cellular mechanism behind muscle repair uncovered!

Cellular mechanism behind muscle repair uncovered!

36

How aging reshapes cells across the entire mammalian body

How aging reshapes cells across the entire mammali...

57

Keeping cells’ recycling system in balance

Keeping cells’ recycling system in balance

35

How the cells compensate for the faulty transcription?

How the cells compensate for the faulty transcript...

37

ER remodelling in ageing!

ER remodelling in ageing!

30

GlycoRNA’s control growth factor signaling!

GlycoRNA’s control growth factor signaling!

84

How bacteria suppress immune defenses in stubborn wound infections

How bacteria suppress immune defenses in stubborn ...

20

Bacteria found in mouth and gut may help protect against severe peanut allergies

Bacteria found in mouth and gut may help protect a...

19

Molecular mechanism regulating bacterial cell division discovered

Molecular mechanism regulating bacterial cell divi...

40

Infant probiotic design from global microbiome atlas

Infant probiotic design from global microbiome atlas

30

Structures of hantavirus glycoprotein tetramers

Structures of hantavirus glycoprotein tetramers

37

Key protein that stops malaria parasite growth identified!

Key protein that stops malaria parasite growth ide...

36

Microbial interactions predict gut health

Microbial interactions predict gut health

39

Broad protection against many respiratory infections and allergens by a single vaccine

Broad protection against many respiratory infectio...

28

How respiratory bacterium obtains essential lipids from the host

How respiratory bacterium obtains essential lipids...

29

How both human and bacterial genes shape oral microbiome

How both human and bacterial genes shape oral micr...

87

Previously unknown bacterial component in kidney stone formation

Previously unknown bacterial component in kidney s...

42

Gut bacteria may tip the balance between feeding tumors and fueling immunity

Gut bacteria may tip the balance between feeding t...

86

How light suppresses virulence in antibiotic-resistant pathogen

How light suppresses virulence in antibiotic-resis...

78

A developmental atlas for genes and cells

A developmental atlas for genes and cells

21

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

60

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

52

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

131

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

117

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

120

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

134

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

214

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

274

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

307

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

321

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

294

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

310

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

25

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

28

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

32

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

97

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

182

How cucumbers got longer?

How cucumbers got longer?

143

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

97

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

111

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

101

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

171

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

376

How plants sense heat during the day

How plants sense heat during the day

335

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

306

How the fats we eat shape our ability to fight disease

How the fats we eat shape our ability to fight dis...

32

How immune cells extract nuclear DNA from dying cells

How immune cells extract nuclear DNA from dying cells

63

How the immune system recognizes viral RNA

How the immune system recognizes viral RNA

46

How dietary restriction rewires immunity to protect against infection

How dietary restriction rewires immunity to protec...

31

How chronic inflammation rewires macrophages

How chronic inflammation rewires macrophages

100

How a common immunosuppressive drug “ATG” injures liver blood vessels

How a common immunosuppressive drug “ATG” injures ...

36

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

35

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

64

Fat surrounding the colon interacts with the immune system

Fat surrounding the colon interacts with the immun...

132

How inflammatory bowel disease promotes colorectal cancer

How inflammatory bowel disease promotes colorectal...

99

How gut pain-sensing neurons elicit immune response

How gut pain-sensing neurons elicit immune response

76

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

123

Human T-cell receptor–CD3 complex structure unraveled!

Human T-cell receptor–CD3 complex structure unrave...

100

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

90

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

375

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

271

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

729

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

354

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

341

Printed skin to replace animal testing

Printed skin to replace animal testing

347

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

323

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

341

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

370

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

370

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

13

Glycoprotein heterodimers on nanoparticles for hepatitis C virus vaccine design

Glycoprotein heterodimers on nanoparticles for hep...

24

Assay to analyze regulatory function and epigenomic modifications simultaneously

Assay to analyze regulatory function and epigenomi...

39

Peptide ligase–mediated display

Peptide ligase–mediated display

28

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

31

How bacteria bind to different types of cells

How bacteria bind to different types of cells

16

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

44

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

39

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

51

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

55

‘Revoice’ device gives stroke patients their voice back

‘Revoice’ device gives stroke patients their voice...

70

Specialized transporters relay lipids to cellular targets

Specialized transporters relay lipids to cellular ...

61

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

60

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

112

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

302

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

296

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

311

How the brain regulates emotions

How the brain regulates emotions

389

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

385

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

371

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

416

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

383

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

390

Link between dietary choices and brain health

Link between dietary choices and brain health

361

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

318

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

440

Research

Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement

Astrocyte-microglia crosstalk through Hevin and To...

9

Sequence and chemical specificity define the functional landscape of intrinsically disordered regions

Sequence and chemical specificity define the funct...

9

A gain-of-function Retsat variant from high-altitude adaptation promotes myelination via a neuronal dihydroretinoic acid-RXR-γ pathway

A gain-of-function Retsat variant from high-altitu...

8

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

13

C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation through genome-wide DNA:RNA hybrid G-quadruplexes

C9orf72 hexanucleotide repeat RNA drives transcrip...

22

Lipid droplet-induced T cell death sustains autoimmune tissue inflammation

Lipid droplet-induced T cell death sustains autoim...

24

Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections

Enterococcus faecalis-derived lactic acid suppress...

12

Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex

Multi-modal dissection of cell-type specific TDP-4...

14

Medullary and C3–C4 propriospinal pathways underlying mammalian forelimb movement control

Medullary and C3–C4 propriospinal pathways underly...

36

Assembly of helper NLR resistosome clusters upon activation of a coiled-coil NLR

Assembly of helper NLR resistosome clusters upon a...

12

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis

Microbial metabolism of food allergens determines ...

12

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

30

Cell-autonomous and non-cell-autonomous drivers of dopamine neuron vulnerability in Parkinson’s disease

Cell-autonomous and non-cell-autonomous drivers of...

45

Astrocyte-microglia crosstalk through Hevin and Toll-like receptor signaling controls developmental thalamocortical synapse refinement

Astrocyte-microglia crosstalk through Hevin and To...

9

Sequence and chemical specificity define the functional landscape of intrinsically disordered regions

Sequence and chemical specificity define the funct...

9

A gain-of-function Retsat variant from high-altitude adaptation promotes myelination via a neuronal dihydroretinoic acid-RXR-γ pathway

A gain-of-function Retsat variant from high-altitu...

8

C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation through genome-wide DNA:RNA hybrid G-quadruplexes

C9orf72 hexanucleotide repeat RNA drives transcrip...

22

Lipid droplet-induced T cell death sustains autoimmune tissue inflammation

Lipid droplet-induced T cell death sustains autoim...

24

Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections

Enterococcus faecalis-derived lactic acid suppress...

12

Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex

Multi-modal dissection of cell-type specific TDP-4...

14

Medullary and C3–C4 propriospinal pathways underlying mammalian forelimb movement control

Medullary and C3–C4 propriospinal pathways underly...

36

Assembly of helper NLR resistosome clusters upon activation of a coiled-coil NLR

Assembly of helper NLR resistosome clusters upon a...

12

Microbial metabolism of food allergens determines the severity of IgE-mediated anaphylaxis

Microbial metabolism of food allergens determines ...

12

Cell-autonomous and non-cell-autonomous drivers of dopamine neuron vulnerability in Parkinson’s disease

Cell-autonomous and non-cell-autonomous drivers of...

45

Enhancer dynamics and cellular architecture in the human spinal cord

Enhancer dynamics and cellular architecture in the...

28

Native-like soluble E1E2 glycoprotein heterodimers on self-assembling protein nanoparticles for hepatitis C virus vaccine design

Native-like soluble E1E2 glycoprotein heterodimers...

16

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

13

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

30

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Simultaneous epigenomic profiling and regulatory a...

35

Single-cell and isoform-specific translational profiling of the mouse brain

Single-cell and isoform-specific translational pro...

44

Medaka: a novel model for analyzing genome– environment interactions

Medaka: a novel model for analyzing genome– enviro...

4597

Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization

Development of human induced pluripotent stem cell...

43

Challenges and opportunities in adapting high-throughput functional assays for in vivo neuroscience

Challenges and opportunities in adapting high-thro...

56

Synthetic serum markers enable noninvasive monitoring of gene expression in primate brains

Synthetic serum markers enable noninvasive monitor...

33

Peptide ligase–mediated display: A cell-free platform for tunable selection of affinity peptides

Peptide ligase–mediated display: A cell-free platf...

2464

Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury

Brain-wide mapping of oligodendrocyte organization...

45

A unified framework combining linear and 3D molecular features for robust drug-protein interaction prediction

A unified framework combining linear and 3D molecu...

58

Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

Multi-omic analysis of guided and unguided forebra...

67

3D multiparametric ultrasound imaging of steatotic liver disease in a study with male rats

3D multiparametric ultrasound imaging of steatotic...

66

THALASSEMIA

THALASSEMIA

38

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

56

NMDA RECEPTORS

NMDA RECEPTORS

89

Neural Development

Neural Development

64

Transcription Factors

Transcription Factors

135

Interferons

64

RABIES

43

ANEMIA

33

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

47

Migraine

26

Dementia

77

Trisomy

48

Cystic Fibrosis

Cystic Fibrosis

54

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

73836

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1235

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1130

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3802

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

382

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

372

HEAD AND NECK CANCER

HEAD AND NECK CANCER

397

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

237

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

364

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

409

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

351

Gestational diabetes therapeutics

Gestational diabetes therapeutics

342

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

372

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

545

Different types of Alzheimer's disease

Different types of Alzheimer's disease

453

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

410

Alzheimer’s therapeutics

Alzheimer’s therapeutics

410

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

408

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

430

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

379

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

391

APOE in Alzheimer’s

APOE in Alzheimer’s

464

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

531

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

545

Different types of Alzheimer's disease

Different types of Alzheimer's disease

453

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

410

Alzheimer’s therapeutics

Alzheimer’s therapeutics

410

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

408

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

430

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

379

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

391

APOE in Alzheimer’s

APOE in Alzheimer’s

464

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

531

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

379

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

421

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

361

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

351

Gestational diabetes therapeutics

Gestational diabetes therapeutics

342

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

372