Index - Sciencemission

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

3

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

Science Hangouts

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

2

Science News Highlights

Regulation of dendritic spine formation and synaptic development by ARMS

News highlights

Regulation of dendritic spine formation and synaptic development by ARMS

5

Gut microbiota and type-2 diabetes risk in youth

News highlights

Gut microbiota and type-2 diabetes risk in youth

5

The role of cytokine receptor Fn14 in adult brain

News highlights

The role of cytokine receptor Fn14 in adult brain

5

News

A drug to cure jet lag?

A drug to cure jet lag?

24

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

15

Chronic cellular stress promotes liver cancer but also enhances immunotherapy efficiency

Chronic cellular stress promotes liver cancer but ...

16

PD as a SCAN disorder!

PD as a SCAN disorder!

13

Characterizing human dermal sleeping pain neurons

Characterizing human dermal sleeping pain neurons

13

How longevity is inherited across generations

How longevity is inherited across generations

48

How respiratory bacterium obtains essential lipids from the host

How respiratory bacterium obtains essential lipids...

13

ER remodelling in ageing!

ER remodelling in ageing!

13

Convergent molecular pathways across distinct genetic forms of autism

Convergent molecular pathways across distinct gen...

12

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

26

sncRNAs in sperm aging

sncRNAs in sperm aging

19

Stress-related memory issues in women from high estrogen levels in brain

Stress-related memory issues in women from high es...

20

How bacteria bind to different types of cells

How bacteria bind to different types of cells

13

A drug to cure jet lag?

A drug to cure jet lag?

24

PD as a SCAN disorder!

PD as a SCAN disorder!

13

Characterizing human dermal sleeping pain neurons

Characterizing human dermal sleeping pain neurons

13

Convergent molecular pathways across distinct genetic forms of autism

Convergent molecular pathways across distinct gen...

12

Stress-related memory issues in women from high estrogen levels in brain

Stress-related memory issues in women from high es...

20

Aging brains pile up damaged synaptic proteins in microglia

Aging brains pile up damaged synaptic proteins in ...

92

Aberrant nuclear pore complex degradation contributes to neurodegeneration

Aberrant nuclear pore complex degradation contribu...

29

Gut immune cells drive Parkinson’s development via gut-brain axis

Gut immune cells drive Parkinson’s development via...

64

A skin biopsy to detect a rare neurodegenerative disease

A skin biopsy to detect a rare neurodegenerative d...

32

Why we sleep poorly in new environments

Why we sleep poorly in new environments

37

A new brain atlas identifies SLC45A1-associated disease as a lysosomal disorder

A new brain atlas identifies SLC45A1-associated di...

38

How a chaperone protein enhances memory

How a chaperone protein enhances memory

30

Brain networks work together for general intelligence!

Brain networks work together for general intellige...

55

Chronic cellular stress promotes liver cancer but also enhances immunotherapy efficiency

Chronic cellular stress promotes liver cancer but ...

16

How extra cellular matrix boosts triple negative breast cancer’s ability to metastasize

How extra cellular matrix boosts triple negative b...

30

How microRNA regulates intratumoral heterogeneity

How microRNA regulates intratumoral heterogeneity

32

What causes human cancers?

What causes human cancers?

81

Small number of ‘highly plastic’ cancer cells drive disease progression and treatment resistance

Small number of ‘highly plastic’ cancer cells driv...

31

Blood test can to identify cancer in patients with non-specific symptoms

Blood test can to identify cancer in patients with...

59

Chemotherapy rewires gut bacteria to curb metastasis

Chemotherapy rewires gut bacteria to curb metastasis

65

How cancer cells protect themselves from the immune system

How cancer cells protect themselves from the immun...

76

A novel mechanism for cancer-associated weight loss

A novel mechanism for cancer-associated weight loss

82

Tissue-resident microbiota impacts colorectal cancer progression and prognosis

Tissue-resident microbiota impacts colorectal canc...

52

Inflammation fuels one of the most aggressive forms of cancer

Inflammation fuels one of the most aggressive form...

108

Origin cells for malignant brain tumor identified

Origin cells for malignant brain tumor identified

63

High-fat diets make liver cells more likely to become cancerous

High-fat diets make liver cells more likely to bec...

183

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

46

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

67

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

37

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

64

Exposure to natural light improves metabolic health

Exposure to natural light improves metabolic health

88

Gut microbial bileacids in infancy may influence the risk of type 1 diabetes

Gut microbial bileacids in infancy may influence t...

50

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

47

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

167

How the Immune System Stalls Weight Loss

How the Immune System Stalls Weight Loss

156

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

309

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

155

Mitochondrial ketone body oxidation impaired in diabetes & liver disease

Mitochondrial ketone body oxidation impaired in di...

132

Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

Sons of mothers with type 1 diabetes show early si...

85

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

15

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

28

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

65

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

79

Gene therapy for chronic pain?

Gene therapy for chronic pain?

55

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

63

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

49

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

56

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

54

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

84

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

121

AI-based software maps proteins and lipids within cells

AI-based software maps proteins and lipids within ...

98

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

115

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

51

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

34

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

57

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

106

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

90

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

110

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

143

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

117

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

150

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

173

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

149

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

329

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

306

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

49

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

174

How cell walls guide stem cells

How cell walls guide stem cells

49

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

70

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

69

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

77

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

58

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

54

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

93

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

184

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

70

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

93

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

83

How longevity is inherited across generations

How longevity is inherited across generations

48

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

26

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

67

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

52

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

40

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

81

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

62

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

59

Gene linked with risk of delirium

Gene linked with risk of delirium

62

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

96

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

88

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

109

A genome-to-proteome map

A genome-to-proteome map

121

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

60

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

68

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

108

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

397

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

414

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

383

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

408

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

281

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

373

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

427

Role of ECM in brain memory

Role of ECM in brain memory

375

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

388

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

390

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

41

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

31

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

38

A novel inflammatory function of platelets

A novel inflammatory function of platelets

50

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

53

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

66

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

59

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

89

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

97

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

73

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

111

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

77

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

96

sncRNAs in sperm aging

sncRNAs in sperm aging

19

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

79

How reproductive organs form

How reproductive organs form

63

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

91

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

79

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

112

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

165

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

116

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

85

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

98

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

102

Functional eggs from human skin cells

Functional eggs from human skin cells

93

Sperm microRNAs regulate paternal transmission of exercise capacity

Sperm microRNAs regulate paternal transmission of ...

105

ER remodelling in ageing!

ER remodelling in ageing!

13

GlycoRNA’s control growth factor signaling!

GlycoRNA’s control growth factor signaling!

69

Bile acid transport mechanism

Bile acid transport mechanism

38

Compensatory epigenetic mechanisms to control genes

Compensatory epigenetic mechanisms to control genes

22

New drug candidate reverses metabolic liver disease and fibrosis

New drug candidate reverses metabolic liver diseas...

89

In vitro transcription may be getting cheaper!

In vitro transcription may be getting cheaper!

36

Why face scars less than the body

Why face scars less than the body

44

Substrate recognition mechanism of Golgi membrane-associated degradation (GOMED)

Substrate recognition mechanism of Golgi membrane-...

46

Cas12a3 cleaves tRNA tails!

Cas12a3 cleaves tRNA tails!

46

Repairing damaged lysosomal membrane

Repairing damaged lysosomal membrane

79

Regulating protein production

Regulating protein production

54

How cells eliminate inefficient ribosomes

How cells eliminate inefficient ribosomes

26

A non-coding gene controls cell size

A non-coding gene controls cell size

46

How respiratory bacterium obtains essential lipids from the host

How respiratory bacterium obtains essential lipids...

13

How both human and bacterial genes shape oral microbiome

How both human and bacterial genes shape oral micr...

62

Previously unknown bacterial component in kidney stone formation

Previously unknown bacterial component in kidney s...

22

Gut bacteria may tip the balance between feeding tumors and fueling immunity

Gut bacteria may tip the balance between feeding t...

67

How light suppresses virulence in antibiotic-resistant pathogen

How light suppresses virulence in antibiotic-resis...

67

Breath carries clues to gut microbiome health

Breath carries clues to gut microbiome health

41

A protein found in the GI tract can neutralize many bacteria

A protein found in the GI tract can neutralize man...

84

Replacing microbiota makes aging intestines young again

Replacing microbiota makes aging intestines young ...

63

New treatment for drug-resistant fungal infections

New treatment for drug-resistant fungal infections

49

Microbes in breast milk help populate infant gut microbiomes

Microbes in breast milk help populate infant gut m...

51

Virus-drug structure, interaction in real time

Virus-drug structure, interaction in real time

63

A high-protein diet can defeat cholera infection

A high-protein diet can defeat cholera infection

64

Small RNA coded by phage controls infection

Small RNA coded by phage controls infection

69

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

50

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

41

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

117

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

107

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

111

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

119

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

194

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

262

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

295

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

307

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

285

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

300

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

420

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

81

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

168

How cucumbers got longer?

How cucumbers got longer?

132

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

86

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

105

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

92

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

157

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

365

How plants sense heat during the day

How plants sense heat during the day

326

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

298

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

344

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

349

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

376

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

23

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

46

Fat surrounding the colon interacts with the immune system

Fat surrounding the colon interacts with the immun...

114

How inflammatory bowel disease promotes colorectal cancer

How inflammatory bowel disease promotes colorectal...

86

How gut pain-sensing neurons elicit immune response

How gut pain-sensing neurons elicit immune response

66

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

109

Human T-cell receptor–CD3 complex structure unraveled!

Human T-cell receptor–CD3 complex structure unrave...

87

Key lung immune cells can intensify allergic reactions

Key lung immune cells can intensify allergic react...

226

A new vulnerability of asthma immune cells discovered

A new vulnerability of asthma immune cells discovered

85

Why the 'gut brain' plays a central role for allergies

Why the 'gut brain' plays a central role for aller...

99

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

67

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

122

Oxygen deprivation drives dysfunctional neutrophil immunity

Oxygen deprivation drives dysfunctional neutrophil...

111

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

79

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

364

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

258

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

719

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

342

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

329

Printed skin to replace animal testing

Printed skin to replace animal testing

338

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

314

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

333

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

357

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

360

How bacteria bind to different types of cells

How bacteria bind to different types of cells

13

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

32

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

27

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

36

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

42

‘Revoice’ device gives stroke patients their voice back

‘Revoice’ device gives stroke patients their voice...

56

Specialized transporters relay lipids to cellular targets

Specialized transporters relay lipids to cellular ...

48

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

50

Redox and pH changes shuts down AQP3 channel

Redox and pH changes shuts down AQP3 channel

75

Mapping the human genome in 4D

Mapping the human genome in 4D

101

Using a microfluidic device to monitor glioblastoma treatment outcomes

Using a microfluidic device to monitor glioblastom...

53

Enzyme catalysis using thiol switching!

Enzyme catalysis using thiol switching!

64

Plant hormone based system for complete degradation of a specific target protein in vivo

Plant hormone based system for complete degradatio...

62

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

101

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

296

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

283

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

300

How the brain regulates emotions

How the brain regulates emotions

377

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

373

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

361

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

407

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

376

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

381

Link between dietary choices and brain health

Link between dietary choices and brain health

352

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

299

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

429

Research

A non-canonical ARMS-GABARAP interaction modulates dendritic spine formation and synaptic development

A non-canonical ARMS-GABARAP interaction modulates...

8

Neural and computational mechanisms underlying one-shot perceptual learning in humans

Neural and computational mechanisms underlying one...

6

Parkinson’s disease as a somato-cognitive action network disorder

Parkinson’s disease as a somato-cognitive action n...

215

Gut microbiota and metabolic disease risk in youth

Gut microbiota and metabolic disease risk in youth

13

Molecular architecture of human dermal sleeping nociceptors

Molecular architecture of human dermal sleeping no...

8

Fn14 is an activity-dependent, Bmal1-regulated cytokine receptor that induces rod-like microglia and restricts neuronal activity in vivo

Fn14 is an activity-dependent, Bmal1-regulated cyt...

22

Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions

Sources of essential lipids for Mycoplasma pneumon...

10

ER remodelling is a feature of ageing and depends on ER-phagy

ER remodelling is a feature of ageing and depends ...

16

Developmental convergence and divergence in human stem cell models of autism

Developmental convergence and divergence in human ...

9

Dynamic allele usage of X-linked genes ameliorates neurodevelopmental disease phenotypes in brain organoids

Dynamic allele usage of X-linked genes ameliorates...

14

Conserved shifts in sperm small non-coding RNA profiles during mouse and human aging

Conserved shifts in sperm small non-coding RNA pro...

17

Lysosomes as hubs of metabolic sensing and cellular homeostasis

Lysosomes as hubs of metabolic sensing and cellula...

36

Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

Sleep disturbance triggers aberrant activation of ...

65

A non-canonical ARMS-GABARAP interaction modulates dendritic spine formation and synaptic development

A non-canonical ARMS-GABARAP interaction modulates...

8

Neural and computational mechanisms underlying one-shot perceptual learning in humans

Neural and computational mechanisms underlying one...

6

Parkinson’s disease as a somato-cognitive action network disorder

Parkinson’s disease as a somato-cognitive action n...

215

Gut microbiota and metabolic disease risk in youth

Gut microbiota and metabolic disease risk in youth

13

Molecular architecture of human dermal sleeping nociceptors

Molecular architecture of human dermal sleeping no...

8

Fn14 is an activity-dependent, Bmal1-regulated cytokine receptor that induces rod-like microglia and restricts neuronal activity in vivo

Fn14 is an activity-dependent, Bmal1-regulated cyt...

22

Sources of essential lipids for Mycoplasma pneumoniae via P116 to target liver and atherosclerotic lesions

Sources of essential lipids for Mycoplasma pneumon...

10

ER remodelling is a feature of ageing and depends on ER-phagy

ER remodelling is a feature of ageing and depends ...

16

Developmental convergence and divergence in human stem cell models of autism

Developmental convergence and divergence in human ...

9

Dynamic allele usage of X-linked genes ameliorates neurodevelopmental disease phenotypes in brain organoids

Dynamic allele usage of X-linked genes ameliorates...

14

Conserved shifts in sperm small non-coding RNA profiles during mouse and human aging

Conserved shifts in sperm small non-coding RNA pro...

17

Lysosomes as hubs of metabolic sensing and cellular homeostasis

Lysosomes as hubs of metabolic sensing and cellula...

36

Sleep disturbance triggers aberrant activation of vagus circuitry and induces intestinal stem cell dysfunction

Sleep disturbance triggers aberrant activation of ...

65

A unified framework combining linear and 3D molecular features for robust drug-protein interaction prediction

A unified framework combining linear and 3D molecu...

32

Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

Multi-omic analysis of guided and unguided forebra...

41

3D multiparametric ultrasound imaging of steatotic liver disease in a study with male rats

3D multiparametric ultrasound imaging of steatotic...

41

A universal polyphosphate kinase powers in vitro transcription

A universal polyphosphate kinase powers in vitro t...

48

Fluorescent indicators for visualizing dynamic contact between cells and between processes originating from a single cell

Fluorescent indicators for visualizing dynamic con...

58

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics

HT SpaceM: A high-throughput and reproducible meth...

60

Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

Chimeric brain models to study human glial-neurona...

65

Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Mapping cellular targets of covalent cancer drugs ...

81

Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel

Dynamic release of extracellular particles after o...

71

Activation of enzymatic catalysis via nucleic acid hybridization affords synergistic coupling of specificity, potency, and signal amplification

Activation of enzymatic catalysis via nucleic acid...

67

Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities

Spatially resolved microRNA expression in tissues:...

71

CaBLAM: a high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

CaBLAM: a high-contrast bioluminescent Ca2+ indica...

65

Nondestructive X-ray tomography of brain tissue ultrastructure

Nondestructive X-ray tomography of brain tissue ul...

52

Cystic Fibrosis

Cystic Fibrosis

30

Brainstem lesions

Brainstem lesions

53

THE LIMBIC SYSTEM

THE LIMBIC SYSTEM

199

MITOCHONDRIAL DISEASES

MITOCHONDRIAL DISEASES

172

NEURO- MUSCULAR JUNCTION

NEURO- MUSCULAR JUNCTION

111

Caffeine

135

Diabetic Neuropathy

Diabetic Neuropathy

110

Neural Transmission

Neural Transmission

107

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

104

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

318

Potassium Channels

Potassium Channels

177

Calcium channels physiology and Therapeutics uses

Calcium channels physiology and Therapeutics uses

207

Cell Signaling and Communication between Cells

Cell Signaling and Communication between Cells

468

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

70703

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1162

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1071

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3413

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

367

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

361

HEAD AND NECK CANCER

HEAD AND NECK CANCER

383

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

227

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

352

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

397

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

337

Gestational diabetes therapeutics

Gestational diabetes therapeutics

332

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

359

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

529

Different types of Alzheimer's disease

Different types of Alzheimer's disease

431

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

395

Alzheimer’s therapeutics

Alzheimer’s therapeutics

389

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

385

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

408

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

357

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

375

APOE in Alzheimer’s

APOE in Alzheimer’s

438

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

508

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

529

Different types of Alzheimer's disease

Different types of Alzheimer's disease

431

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

395

Alzheimer’s therapeutics

Alzheimer’s therapeutics

389

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

385

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

408

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

357

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

375

APOE in Alzheimer’s

APOE in Alzheimer’s

438

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

508

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

366

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

401

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

342

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

337

Gestational diabetes therapeutics

Gestational diabetes therapeutics

332

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

359