Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

15443

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

46

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

56

Science News Highlights

Obesity memory!

News highlights

Obesity memory!

10

GABAB receptor plasticity

News highlights

GABAB receptor plasticity

18

How neurons regulate intestinal immune homeostasis

News highlights

How neurons regulate intestinal immune homeostasis

17

News

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

4

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

38

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

29

How Alzheimer’s risk factor, APOE4, damages blood vessels?

How Alzheimer’s risk factor, APOE4, damages blood ...

34

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

60

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

29

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

29

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

40

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

31

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

35

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

53

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

61

Neuroprosthesis for paralysis enables simultaneous speech and body language

Neuroprosthesis for paralysis enables simultaneous...

90

How Alzheimer’s risk factor, APOE4, damages blood vessels?

How Alzheimer’s risk factor, APOE4, damages blood ...

34

Neuroprosthesis for paralysis enables simultaneous speech and body language

Neuroprosthesis for paralysis enables simultaneous...

90

Brain activity can predict a risky decision before it’s made

Brain activity can predict a risky decision before...

51

Why some Huntington disease patients decline years earlier

Why some Huntington disease patients decline years...

49

Mitochondrial transfer from bone marrow transplant in mitochondrial disease

Mitochondrial transfer from bone marrow transplant...

97

Autism-risk mutations reveal two opposing patterns of brain gene activity

Autism-risk mutations reveal two opposing patterns...

57

TRPM2 is a direct transducer for chronic pain

TRPM2 is a direct transducer for chronic pain

46

Intermittent fasting shows promise in slowing Huntington’s disease progression

Intermittent fasting shows promise in slowing Hunt...

78

Locus coeruleus noradrenaline neurons mapped!

Locus coeruleus noradrenaline neurons mapped!

102

Psychedelics and anesthetics create mirror image patterns in the brain

Psychedelics and anesthetics create mirror image p...

56

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

90

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

122

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

92

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

60

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

55

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

43

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

62

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

68

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

52

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

67

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

87

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

90

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

107

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

98

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

97

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

103

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

59

Mechanism of obesity relapse

Mechanism of obesity relapse

166

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

119

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

105

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

505

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

172

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

198

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

235

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

272

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

258

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

232

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

267

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

269

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

38

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

29

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

31

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

85

AI language models for aging biology

AI language models for aging biology

118

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

72

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

101

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

135

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

104

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

70

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

213

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

188

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

77

Protein-based data storage

Protein-based data storage

209

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

203

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

214

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

356

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

275

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

321

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

377

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

365

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

334

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

374

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

335

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

412

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

398

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

103

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

100

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

74

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

115

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

95

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

116

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

108

A novel 3D brain tissue model

A novel 3D brain tissue model

141

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

123

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

115

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

198

Reverting aged cells to stem cells

Reverting aged cells to stem cells

263

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

144

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

4

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

50

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

56

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

58

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

48

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

59

Generational chromosome repair!

Generational chromosome repair!

60

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

59

Is our personality written in our genes?

Is our personality written in our genes?

161

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

81

How chromosomes find their partners

How chromosomes find their partners

152

New gene activation tool!

New gene activation tool!

108

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

122

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

47

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

61

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

85

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

133

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

165

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

167

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

156

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

157

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

258

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

284

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

279

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

299

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

609

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

29

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

47

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

66

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

88

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

93

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

91

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

118

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

106

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

116

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

140

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

138

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

183

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

163

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

110

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

61

Postbiotics may boost female fertility

Postbiotics may boost female fertility

127

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

133

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

136

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

201

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

208

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

245

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

229

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

292

sncRNAs in sperm aging

sncRNAs in sperm aging

346

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

279

How reproductive organs form

How reproductive organs form

380

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

40

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

33

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

47

How a protein shapes the cell membrane

How a protein shapes the cell membrane

58

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

77

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

48

How blood cells release key signaling lipid

How blood cells release key signaling lipid

63

Transcription of eight letter codon!

Transcription of eight letter codon!

78

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

78

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

65

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

69

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

93

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

103

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

53

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

59

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

62

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

104

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

48

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

61

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

109

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

94

Methylation puts parasites in motion

Methylation puts parasites in motion

73

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

174

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

211

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

134

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

120

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

119

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

63

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

69

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

73

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

75

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

81

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

113

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

159

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

166

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

154

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

147

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

178

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

158

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

52

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

44

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

84

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

83

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

93

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

167

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

143

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

150

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

144

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

144

Cure for dry eye disease

Cure for dry eye disease

180

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

194

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

204

Why some people can fight infections better than others?

Why some people can fight infections better than o...

106

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

92

Gene circuits of human immunity

Gene circuits of human immunity

108

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

99

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

114

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

78

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

101

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

93

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

94

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

107

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

97

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

127

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

102

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

38

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

100

Air-permeable hydrogels!

Air-permeable hydrogels!

149

Temperature behaves differently in the cell

Temperature behaves differently in the cell

146

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

130

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

178

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

203

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

275

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

555

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

447

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

933

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

546

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

527

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

29

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

35

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

61

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

51

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

89

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

96

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

74

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

90

Viral RNA elements functional map!

Viral RNA elements functional map!

84

How proteins change shape and move

How proteins change shape and move

90

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

95

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

147

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

92

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

161

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

304

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

494

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

515

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

477

How the brain regulates emotions

How the brain regulates emotions

706

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

562

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

565

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

580

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

550

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

545

Link between dietary choices and brain health

Link between dietary choices and brain health

516

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

507

Research

Mapping enhancer–gene regulatory interactions from single-cell data

Mapping enhancer–gene regulatory interactions from...

9

The epigenetic and metabolic basis of obesity memory

The epigenetic and metabolic basis of obesity memory

17

Reimagining research papers as interactive and reliable AI agents

Reimagining research papers as interactive and rel...

22

Molecular-level observation of the self-assembly of a virus-like particle

Molecular-level observation of the self-assembly o...

25

A pericyte-to-myofibroblast transition links APOE4 to cerebrovascular degeneration

A pericyte-to-myofibroblast transition links APOE4...

23

DNA methylation: unifying framework for complex chronic conditions

DNA methylation: unifying framework for complex ch...

24

Deep learning aging marker from retinal images unveils sex-specific clinical and genetic signatures

Deep learning aging marker from retinal images unv...

28

On the nature of GABAB receptors and their plasticity in the mammalian brain

On the nature of GABAB receptors and their plastic...

43

Ligand-induced activation of RyR1 in native membranes

Ligand-induced activation of RyR1 in native membranes

58

Trimethylamine-N-oxide: the microbial cue in immune-mediated disorders

Trimethylamine-N-oxide: the microbial cue in immun...

926

Sleep-dependent microglial functions in Alzheimer’s disease

Sleep-dependent microglial functions in Alzheimer’...

39

Rapid patient-specific neural networks for intraoperative X-ray to volume registration

Rapid patient-specific neural networks for intraop...

24

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

78

Mapping enhancer–gene regulatory interactions from single-cell data

Mapping enhancer–gene regulatory interactions from...

9

The epigenetic and metabolic basis of obesity memory

The epigenetic and metabolic basis of obesity memory

17

Reimagining research papers as interactive and reliable AI agents

Reimagining research papers as interactive and rel...

22

Molecular-level observation of the self-assembly of a virus-like particle

Molecular-level observation of the self-assembly o...

25

A pericyte-to-myofibroblast transition links APOE4 to cerebrovascular degeneration

A pericyte-to-myofibroblast transition links APOE4...

23

DNA methylation: unifying framework for complex chronic conditions

DNA methylation: unifying framework for complex ch...

24

Deep learning aging marker from retinal images unveils sex-specific clinical and genetic signatures

Deep learning aging marker from retinal images unv...

28

On the nature of GABAB receptors and their plasticity in the mammalian brain

On the nature of GABAB receptors and their plastic...

43

Ligand-induced activation of RyR1 in native membranes

Ligand-induced activation of RyR1 in native membranes

58

Trimethylamine-N-oxide: the microbial cue in immune-mediated disorders

Trimethylamine-N-oxide: the microbial cue in immun...

926

Sleep-dependent microglial functions in Alzheimer’s disease

Sleep-dependent microglial functions in Alzheimer’...

39

Rapid patient-specific neural networks for intraoperative X-ray to volume registration

Rapid patient-specific neural networks for intraop...

24

EBV reactivation priming of the peripheral immune system in multiple sclerosis relapse

EBV reactivation priming of the peripheral immune ...

22

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

78

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

152

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

62

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

60

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

58

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

53

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

51

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

51

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

83

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

179

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

285

Automated prototyping of genetic codes

Automated prototyping of genetic codes

285

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

286

Breeding of Cotton

Breeding of Cotton

687

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

901

THALASSEMIA

THALASSEMIA

1019

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

1014

NMDA RECEPTORS

478

Neural Development

Neural Development

462

Transcription Factors

Transcription Factors

452

Interferons

405

RABIES

414

ANEMIA

413

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

401

Migraine

332

Dementia

422

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

2908

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

87

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

79

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

72

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2368

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

44

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

96

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

742

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

88

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

134

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

101

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

665

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

297

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

535

Gestational diabetes therapeutics

Gestational diabetes therapeutics

628

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

581

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

923

Different types of Alzheimer's disease

Different types of Alzheimer's disease

673

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

610

Alzheimer’s therapeutics

Alzheimer’s therapeutics

747

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

632

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

644

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

582

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

577

APOE in Alzheimer’s

APOE in Alzheimer’s

807

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

729

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

923

Different types of Alzheimer's disease

Different types of Alzheimer's disease

673

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

610

Alzheimer’s therapeutics

Alzheimer’s therapeutics

747

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

632

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

644

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

582

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

577

APOE in Alzheimer’s

APOE in Alzheimer’s

807

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

729

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

572

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

740

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

526

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

535

Gestational diabetes therapeutics

Gestational diabetes therapeutics

628

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

581