Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

16381

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

93

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

116

Science News Highlights

Regulation of cardiac nervous system!

News highlights

Regulation of cardiac nervous system!

3

Master fragile X syndrome regulator identified!

News highlights

Master fragile X syndrome regulator identified!

5

Tool to evaluate drug induced molecular phenotypes in 100M single-cell transcriptomics

News highlights

Tool to evaluate drug induced molecular phenotypes in ...

14

News

Reducing pathological pain!

Reducing pathological pain!

31

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

99

How a bacteria senses iron?

How a bacteria senses iron?

44

Effect of processed food on brain metabolism and function

Effect of processed food on brain metabolism and f...

39

AI language models that see every letter

AI language models that see every letter

36

Cigarette smoke may prime lung stem cells for different types of lung cancer

Cigarette smoke may prime lung stem cells for diff...

33

Mapping cellular gene functions with AI and microscopy

Mapping cellular gene functions with AI and micros...

39

Hitting two organs with one common signaling regulator

Hitting two organs with one common signaling regul...

214

How plant enzymes learned to tell mirror-image molecules apart

How plant enzymes learned to tell mirror-image mol...

225

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

577

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

40

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

73

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

59

Reducing pathological pain!

Reducing pathological pain!

31

Effect of processed food on brain metabolism and function

Effect of processed food on brain metabolism and f...

39

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

59

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

48

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

58

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

114

Neck lymph node removal linked to increased risk of cognitive decline

Neck lymph node removal linked to increased risk o...

217

How the biological clock regulates phases of wakefulness

How the biological clock regulates phases of wakef...

97

Prion-like transmission of tau in the mouse brain

Prion-like transmission of tau in the mouse brain

80

What happens in the brain when cannabis makes you anxious?

What happens in the brain when cannabis makes you ...

103

Blocking immune cells’ path into brain limits neurodegeneration

Blocking immune cells’ path into brain limits neur...

207

Brain circuit that remembers stresses identified!

Brain circuit that remembers stresses identified!

187

Alzheimer’s disease and aging reshape brain communication in different ways

Alzheimer’s disease and aging reshape brain commun...

204

Cigarette smoke may prime lung stem cells for different types of lung cancer

Cigarette smoke may prime lung stem cells for diff...

33

Regulating cellular recycling

Regulating cellular recycling

47

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

65

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

114

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

677

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

107

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

114

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

217

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

129

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

90

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

74

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

101

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

109

Hitting two organs with one common signaling regulator

Hitting two organs with one common signaling regul...

214

Microplastics cause fatty liver disease

Microplastics cause fatty liver disease

79

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

437

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

352

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

107

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

90

Mechanism of obesity relapse

Mechanism of obesity relapse

203

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

158

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

141

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

543

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

204

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

238

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

288

AI language models that see every letter

AI language models that see every letter

36

Mapping cellular gene functions with AI and microscopy

Mapping cellular gene functions with AI and micros...

39

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

70

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

597

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

168

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

156

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

245

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

287

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

90

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

87

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

126

AI language models for aging biology

AI language models for aging biology

228

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

119

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

54

Protein-based data storage

Protein-based data storage

243

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

232

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

248

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

391

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

309

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

353

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

419

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

413

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

368

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

404

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

364

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

445

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

77

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

155

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

137

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

134

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

104

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

141

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

123

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

149

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

144

A novel 3D brain tissue model

A novel 3D brain tissue model

171

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

168

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

155

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

227

Heredity is about more than just DNA

Heredity is about more than just DNA

66

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

72

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

166

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

99

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

94

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

85

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

96

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

86

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

102

Generational chromosome repair!

Generational chromosome repair!

94

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

89

Is our personality written in our genes?

Is our personality written in our genes?

192

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

121

Controlling aging muscle

Controlling aging muscle

536

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

138

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

90

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

90

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

121

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

157

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

195

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

202

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

186

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

190

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

289

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

314

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

310

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

69

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

92

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

91

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

75

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

94

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

138

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

121

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

116

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

152

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

140

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

148

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

167

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

167

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

217

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

180

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

86

Postbiotics may boost female fertility

Postbiotics may boost female fertility

159

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

163

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

172

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

253

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

242

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

274

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

260

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

326

sncRNAs in sperm aging

sncRNAs in sperm aging

381

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

306

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

99

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

63

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

3700

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

172

New role for cohesin in DNA replication

New role for cohesin in DNA replication

145

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

81

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

123

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

63

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

79

How a protein shapes the cell membrane

How a protein shapes the cell membrane

86

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

97

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

71

How blood cells release key signaling lipid

How blood cells release key signaling lipid

87

How a bacteria senses iron?

How a bacteria senses iron?

44

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

577

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

46

Alternate pathway of antibiotic resistance

Alternate pathway of antibiotic resistance

61

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

45

How bacteria fight viruses

How bacteria fight viruses

62

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

1124

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

185

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

80

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

80

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

125

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

67

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

82

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

73

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

149

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

79

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

87

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

91

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

94

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

96

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

130

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

188

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

189

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

179

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

175

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

201

How plant enzymes learned to tell mirror-image molecules apart

How plant enzymes learned to tell mirror-image mol...

225

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

40

How plants sense touch?

How plants sense touch?

121

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

77

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

75

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

116

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

105

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

118

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

186

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

166

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

183

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

166

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

168

Sex difference in immune ageing

Sex difference in immune ageing

103

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

97

Why some people can fight infections better than others?

Why some people can fight infections better than o...

123

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

116

Gene circuits of human immunity

Gene circuits of human immunity

138

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

118

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

134

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

100

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

120

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

119

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

113

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

126

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

119

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

80

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

140

Air-permeable hydrogels!

Air-permeable hydrogels!

171

Temperature behaves differently in the cell

Temperature behaves differently in the cell

168

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

150

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

198

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

224

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

306

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

573

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

473

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

960

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

566

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

570

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

526

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

51

A world-first DNA computer

A world-first DNA computer

55

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

102

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

76

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

106

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

79

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

108

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

112

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

91

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

108

Viral RNA elements functional map!

Viral RNA elements functional map!

103

How proteins change shape and move

How proteins change shape and move

111

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

183

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

327

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

511

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

537

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

500

How the brain regulates emotions

How the brain regulates emotions

726

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

592

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

601

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

595

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

571

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

563

Link between dietary choices and brain health

Link between dietary choices and brain health

530

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

527

Research

Evolving perspectives on cardiac innervation: from relay to a complex regulated network

Evolving perspectives on cardiac innervation: from...

9

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target

Translatome profiling reveals opposing alterations...

14

Disruption of the Nav1.8/Ankyrin-3 interaction in nociceptors reduces pathological pain-like behaviors in mice

Disruption of the Nav1.8/Ankyrin-3 interaction in ...

24

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular phenoty...

31

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells

Decline of chaperone-mediated autophagy in aging i...

25

The response regulator BqsR/CarR controls Fe2+ acquisition in Pseudomonas aeruginosa

The response regulator BqsR/CarR controls Fe2+ acq...

27

Metabolic and neural responses to ultraprocessed foods: a randomized, controlled, crossover study

Metabolic and neural responses to ultraprocessed f...

54

Retrofitting language models to operate over bytes

Retrofitting language models to operate over bytes

28

Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis

Distinct cellular phenotypes of language and execu...

25

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex image-...

33

Carbonic anhydrase VIII regulates IP3R1-dependent Ca2+ signaling to coordinate insulin secretion and hepatic glucose production

Carbonic anhydrase VIII regulates IP3R1-dependent ...

30

Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol

Deciphering the evolutionary origin of the enantio...

35

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

95

Evolving perspectives on cardiac innervation: from relay to a complex regulated network

Evolving perspectives on cardiac innervation: from...

9

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of fragile X mice and identifies EPAC2 as a therapeutic target

Translatome profiling reveals opposing alterations...

14

Disruption of the Nav1.8/Ankyrin-3 interaction in nociceptors reduces pathological pain-like behaviors in mice

Disruption of the Nav1.8/Ankyrin-3 interaction in ...

24

Decline of chaperone-mediated autophagy in aging impairs macrophage clearance of senescent cells

Decline of chaperone-mediated autophagy in aging i...

25

The response regulator BqsR/CarR controls Fe2+ acquisition in Pseudomonas aeruginosa

The response regulator BqsR/CarR controls Fe2+ acq...

27

Metabolic and neural responses to ultraprocessed foods: a randomized, controlled, crossover study

Metabolic and neural responses to ultraprocessed f...

54

Retrofitting language models to operate over bytes

Retrofitting language models to operate over bytes

28

Distinct cellular phenotypes of language and executive decline in amyotrophic lateral sclerosis

Distinct cellular phenotypes of language and execu...

25

Carbonic anhydrase VIII regulates IP3R1-dependent Ca2+ signaling to coordinate insulin secretion and hepatic glucose production

Carbonic anhydrase VIII regulates IP3R1-dependent ...

30

Deciphering the evolutionary origin of the enantioselectivity of short-chain dehydrogenases from plants toward 1-borneol

Deciphering the evolutionary origin of the enantio...

35

ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology

ER-liquid condensate contacts sequester FAM134B/C ...

44

A neurovascular survival axis for adult sympathetic neurons

A neurovascular survival axis for adult sympatheti...

35

Glutamine metabolic interaction network reshapes tumor immunotherapy resistance

Glutamine metabolic interaction network reshapes t...

46

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular phenoty...

31

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex image-...

33

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

95

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

57

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

77

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

63

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

100

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

97

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

116

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

199

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

104

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

88

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

76

Breeding of Cotton

Breeding of Cotton

756

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

995

THALASSEMIA

THALASSEMIA

1095

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

1102

NMDA RECEPTORS

492

Neural Development

Neural Development

481

Transcription Factors

Transcription Factors

473

Interferons

419

RABIES

432

ANEMIA

445

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

419

Migraine

349

Dementia

441

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

57

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

66

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

85

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

9773

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

60

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

83

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

2967

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

127

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

118

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

95

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2389

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

63

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

112

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

552

Gestational diabetes therapeutics

Gestational diabetes therapeutics

646

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

597

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

943

Different types of Alzheimer's disease

Different types of Alzheimer's disease

701

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

630

Alzheimer’s therapeutics

Alzheimer’s therapeutics

789

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

675

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

678

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

615

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

613

APOE in Alzheimer’s

APOE in Alzheimer’s

844

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

768

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

943

Different types of Alzheimer's disease

Different types of Alzheimer's disease

701

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

630

Alzheimer’s therapeutics

Alzheimer’s therapeutics

789

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

675

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

678

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

615

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

613

APOE in Alzheimer’s

APOE in Alzheimer’s

844

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

768

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

587

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

780

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

567

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

552

Gestational diabetes therapeutics

Gestational diabetes therapeutics

646

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

597