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All Publications Protocols Presentations Posters
The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation a...

 11

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling

GDF15 suppresses liver inflammation independe...

 7

Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

Green light relieves stress-induced anxiety-l...

 26

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across...

 16

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation a...

 11

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling

GDF15 suppresses liver inflammation independe...

 7

Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

Green light relieves stress-induced anxiety-l...

 26

Histological aging signatures for monitoring tissue-specific aging and disease

Histological aging signatures for monitoring ...

 19

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across...

 16

A molecular cell atlas of endocrine signaling in human neural organoids

A molecular cell atlas of endocrine signaling...

 27

A compendium of next-generation patient-derived models for diverse cancers

A compendium of next-generation patient-deriv...

 60

High-resolution promoter interaction analysis implicates genes involved in activation of type 3 innate lymphoid cells in immune disease risk

High-resolution promoter interaction analysis...

 59

Breeding of Cotton

Breeding of Cotton

 337

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 474

THALASSEMIA

THALASSEMIA

 648

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 627

Oxidative Signaling in Plants

Oxidative Signaling in Plants

 64

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

 80

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 158178

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 1896

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Science Hangouts

Dimerization and activation of receptor tyrosine kinases:  insights from quantitative fluorescence studies
Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

 11839

Editing of Cancer Genomes by APOBEC cytidine deaminases
Science Hangouts

Editing of Cancer Genomes by APOBEC cytidine deaminases

 95

Modeling predisposition to schizophrenia using stem cells
Science Hangouts

Modeling predisposition to schizophrenia using stem cells

 111

Science News Highlights

How green light relieves stress-induced anxiety-like behaviors
News highlights

How green light relieves stress-induced anxiety-like behaviors

 8

What Is Hantavirus?
News highlights

What Is Hantavirus?

 14

Neural reactivation supports memory formation when events end
News highlights

Neural reactivation supports memory formation when eve...

 15

News

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How Parkinson's protein is activated?

How Parkinson's protein is activated?

 0

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 11

Viral RNA elements functional map!

Viral RNA elements functional map!

 15

High-speed microscopy reveals electrical activity across the brain

High-speed microscopy reveals electrical activity ...

 20

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

 39

How proteins change shape and move

How proteins change shape and move

 17

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

 29

Protecting cells from iron overload

Protecting cells from iron overload

 41

Youth-associated protein helps restore healthy function in immune cells in the aging brain

Youth-associated protein helps restore healthy fun...

 37

Alzheimer’s protein patterns vary across populations

Alzheimer’s protein patterns vary across populations

 27

Language-specific brain network identified!

Language-specific brain network identified!

 70

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

 41

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

 30

How Parkinson's protein is activated?

How Parkinson's protein is activated?

 0

High-speed microscopy reveals electrical activity across the brain

High-speed microscopy reveals electrical activity ...

 20

Youth-associated protein helps restore healthy function in immune cells in the aging brain

Youth-associated protein helps restore healthy fun...

 37

Alzheimer’s protein patterns vary across populations

Alzheimer’s protein patterns vary across populations

 27

Language-specific brain network identified!

Language-specific brain network identified!

 70

Memories persist despite temporary synapse loss

Memories persist despite temporary synapse loss

 31

Restoring the silenced Friedreich’s ataxia gene without chromatin modulation

Restoring the silenced Friedreich’s ataxia gene wi...

 26

Astrocytes directly regulate brain circuits involved in memory consolidation

Astrocytes directly regulate brain circuits involv...

 76

How electric stimulation affects neurons, genetic activity

How electric stimulation affects neurons, genetic ...

 50

Targeting sensory nerves after growth plate injuries may bolster healing

Targeting sensory nerves after growth plate injuri...

 31

Engineered human neurons rebuild damaged spinal cord circuits

Engineered human neurons rebuild damaged spinal co...

 42

A lot of immune cells enter the human brain during aging!

A lot of immune cells enter the human brain during...

 37

Immune therapy for Alzheimer's?

Immune therapy for Alzheimer's?

 47

Protecting cells from iron overload

Protecting cells from iron overload

 41

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

 41

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

 30

Tumor-secreted protein promotes lung metastasis

Tumor-secreted protein promotes lung metastasis

 28

Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients

Immune cell dysfunction, not absence, defines skin...

 47

Gut  'molecular switch' to control stress and cancer

Gut 'molecular switch' to control stress and cancer

 42

A new vulnerability in acute myeloid leukemia uncovered!

A new vulnerability in acute myeloid leukemia unco...

 44

Immune ‘off switch’ in cancer cells discovered!

Immune ‘off switch’ in cancer cells discovered!

 113

The amino acid arginine helps the body fight tumors and viral infections

The amino acid arginine helps the body fight tumor...

 59

Fructose drives cancer spread

Fructose drives cancer spread

 89

Transmissible cancer discovered in fish in US and Canada

Transmissible cancer discovered in fish in US and ...

 80

Ketogenic diets may increase cancer risk in the small intestine

Ketogenic diets may increase cancer risk in the sm...

 99

Linking gut microbe to tumor suppression

Linking gut microbe to tumor suppression

 94

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

 384

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

 90

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

 115

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

 141

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

 184

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

 179

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

 162

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

 188

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

 193

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

 208

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

 194

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

 213

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

 219

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

 39

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

 29

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

 51

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

 38

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

 44

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

 56

A foundation model for sleep identifies health risks

A foundation model for sleep identifies health risks

 46

AI discovers variation in local brain aging and cognition across human adulthood

AI discovers variation in local brain aging and co...

 63

AI tool miniaturize and modify proteins without sacrificing function

AI tool miniaturize and modify proteins without sa...

 233

Structure of neuronal epilepsy linked protein unraveled!

Structure of neuronal epilepsy linked protein unra...

 81

AI platform could speed peptide drug discovery

AI platform could speed peptide drug discovery

 91

 AI-designed proteins for imaging inside living cells

 AI-designed proteins for imaging inside living cells

 74

AI model creates functional CRISPR-like nucleases

AI model creates functional CRISPR-like nucleases

 93

Protein-based data storage

Protein-based data storage

 123

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

 130

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

 142

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

 276

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

 201

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

 241

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 299

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 287

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 269

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 301

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 276

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 319

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

 342

A novel 3D brain tissue model

A novel 3D brain tissue model

 59

EV  secretome to treat cardiac fibrosis

EV  secretome to treat cardiac fibrosis

 32

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

 46

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

 111

Reverting aged cells to stem cells

Reverting aged cells to stem cells

 181

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

 73

Mechanism linking inflammation and prevention of neuron formation identified!

Mechanism linking inflammation and prevention of n...

 108

Rare stem T cells may hold the key to fighting chronic diseases

Rare stem T cells may hold the key to fighting chr...

 85

Antibiotics reverse damage caused to blood stem cells by chronic Salmonella

Antibiotics reverse damage caused to blood stem ce...

 97

How psychological stress alters gut microbes and ages blood stem cells

How psychological stress alters gut microbes and a...

 108

High fructose during pregnancy impairs stem cell function in the fetal brain

High fructose during pregnancy impairs stem cell f...

 95

“Wnt secreting organizers” in organoids to improve kidney diseases

“Wnt secreting organizers” in organoids to improve...

 91

Microtubule-associated proteins regulate neural stem cell fate and disease

Microtubule-associated proteins regulate neural st...

 97

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

 28

First complete marmoset genome

First complete marmoset genome

 43

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

 83

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

 77

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

 93

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

 102

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

 129

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

 152

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

 154

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

 171

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

 187

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

 165

How longevity is inherited across generations

How longevity is inherited across generations

 247

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

 56

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

 96

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

 100

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

 91

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

 87

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

 181

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

 214

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

 219

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

 239

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

 552

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 545

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 534

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 638

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

 41

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

 58

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

 71

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

 76

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

 107

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

 96

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

 90

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

 112

Mutations in gene regulatory region linked to  heart valve defect

Mutations in gene regulatory region linked to hea...

 113

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

 141

Mechanisms of aortic aneurysm progression

Mechanisms of aortic aneurysm progression

 112

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

 209

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

 172

Postbiotics may boost female fertility

Postbiotics may boost female fertility

 48

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

 73

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

 73

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

 124

Aging human breast atlas reveals  cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

 146

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

 177

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

 172

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

 217

sncRNAs in sperm aging

sncRNAs in sperm aging

 289

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

 228

How reproductive organs form

How reproductive organs form

 328

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

 236

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

 231

How antibiotics work inhibiting RNA polymerase? 

How antibiotics work inhibiting RNA polymerase? 

 32

Mitochondria act as sensors for essential iron molecule

Mitochondria act as sensors for essential iron mol...

 42

Evaluating gut microbial and host proteins in health and disease

Evaluating gut microbial and host proteins in heal...

 44

Role of Golgi complex in DNA repair control

Role of Golgi complex in DNA repair control

 45

Developing potent polyene antifungals

Developing potent polyene antifungals

 55

How muscle cells grow and stay healthy

How muscle cells grow and stay healthy

 62

Role of mitochondrial metabolism and epigenetics in cellular senescence

Role of mitochondrial metabolism and epigenetics i...

 152

Resistance training activates the muscle repair machinery

Resistance training activates the muscle repair ma...

 53

Molecular basis of red–green color vision uncovered!

Molecular basis of red–green color vision uncovered!

 53

Initial steps in the DNA replication!

Initial steps in the DNA replication!

 85

Proteins involved in white blood cell formation identified!

Proteins involved in white blood cell formation id...

 73

Fat stores power the body’s virus defence

Fat stores power the body’s virus defence

 116

Sudden cardiac death condition with linked genetic variations

Sudden cardiac death condition with linked genetic...

 70

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

 105

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

 146

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

 74

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

 61

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

 81

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

 71

Fasting primes gut microbiome to improve intestinal recovery after radiation treatment

Fasting primes gut microbiome to improve intestina...

 78

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

 85

Structural insight into the mechanism of bacterial pili retraction

Structural insight into the mechanism of bacterial...

 89

Microbiota’s hidden role in mosquito-borne disease

Microbiota’s hidden role in mosquito-borne disease

 109

Colorectal cancer signature

Colorectal cancer signature

 82

How bacteria use circadian clocks to colonize

How bacteria use circadian clocks to colonize

 71

A kinase integrating metabolic control with tuberculosis virulence identified!

A kinase integrating metabolic control with tuberc...

 79

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

 63

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

 102

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

 109

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

 103

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

 96

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

 122

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

 102

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

 108

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

 134

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

 135

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

 136

A developmental atlas for genes and cells

A developmental atlas for genes and cells

 185

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

 203

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

 38

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

 108

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

 73

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

 88

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

 84

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

 87

Cure for dry eye disease

Cure for dry eye disease

 115

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

 121

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

 150

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

 130

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

 132

Nicotine Biosynthesis!

Nicotine Biosynthesis!

 262

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

 159

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 11

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

 42

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

 37

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

 53

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

 40

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

 71

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

 52

Breakdown of immune cells’ interaction is key driver in aging

Breakdown of immune cells’ interaction is key driv...

 110

Stimulating vagus nerve may alleviate lung inflammation

Stimulating vagus nerve may alleviate lung inflamm...

 91

Immune cell–fibroblast crosstalk may may drive progression of autoimmune diseases

Immune cell–fibroblast crosstalk may may drive pro...

 83

How mutations affect STING-induced immunity

How mutations affect STING-induced immunity

 105

How newly identified immune cells, ruptoblasts, protect the body

How newly identified immune cells, ruptoblasts, pr...

 91

Nutrient in breast milk that shapes immune development

Nutrient in breast milk that shapes immune develop...

 78

Air-permeable hydrogels!

Air-permeable hydrogels!

 81

Temperature behaves differently in the cell

Temperature behaves differently in the cell

 93

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

 95

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

 129

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

 144

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

 228

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 507

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 406

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 884

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 494

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 470

Printed skin to replace animal testing

Printed skin to replace animal testing

 469

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 466

Viral RNA elements functional map!

Viral RNA elements functional map!

 15

How proteins change shape and move

How proteins change shape and move

 17

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

 39

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

 83

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

 42

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

 49

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

 72

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

 466

Molecular map of liver disease

Molecular map of liver disease

 70

A high-throughput platform to track lipids in action with biosensors

A high-throughput platform to track lipids in acti...

 85

Platform for automated cryo-EM sample preparation and quality control

Platform for automated cryo-EM sample preparation ...

 86

Tracking iron and oxygen levels in cells using LiON

Tracking iron and oxygen levels in cells using LiON

 89

Gene transcription measurement in the living brain

Gene transcription measurement in the living brain

 100

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

 83

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 244

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 439

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 447

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 432

How the brain regulates emotions

How the brain regulates emotions

 646

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 506

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 496

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 541

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 508

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 507

Link between dietary choices and brain health

Link between dietary choices and brain health

 475

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 455

Research

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    • Publications
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The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

 11

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling

GDF15 suppresses liver inflammation independently ...

 7

Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

Green light relieves stress-induced anxiety-like b...

 26

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across enti...

 16

Histological aging signatures for monitoring tissue-specific aging and disease

Histological aging signatures for monitoring tissu...

 19

Large-scale discovery, analysis and design of protein energy landscapes

Large-scale discovery, analysis and design of prot...

 19

What Is Hantavirus?

What Is Hantavirus?

 21

Plasma proteomic profiles of Alzheimer’s disease and neurodegeneration in African cohorts

Plasma proteomic profiles of Alzheimer’s disease a...

 1428

Neural reactivation supports memory formation when events end

Neural reactivation supports memory formation when...

 24

A language network in the individualized functional connectomes of 1199 human brains doing arbitrary tasks

A language network in the individualized functiona...

 38

Hyocholic acids shape neonatal immune tolerance and microbiota assembly

Hyocholic acids shape neonatal immune tolerance an...

 25

Emerging therapeutic opportunities targeting nonclassical MHC-I molecules

Emerging therapeutic opportunities targeting noncl...

 27

A molecular cell atlas of endocrine signaling in human neural organoids

A molecular cell atlas of endocrine signaling in h...

 27

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

 11

GDF15 suppresses liver inflammation independently of weight loss through neuroendocrine glucocorticoid signaling

GDF15 suppresses liver inflammation independently ...

 7

Green light relieves stress-induced anxiety-like behaviors via visual-to-prefrontal projections in mice

Green light relieves stress-induced anxiety-like b...

 26

Histological aging signatures for monitoring tissue-specific aging and disease

Histological aging signatures for monitoring tissu...

 19

Large-scale discovery, analysis and design of protein energy landscapes

Large-scale discovery, analysis and design of prot...

 19

What Is Hantavirus?

What Is Hantavirus?

 21

Plasma proteomic profiles of Alzheimer’s disease and neurodegeneration in African cohorts

Plasma proteomic profiles of Alzheimer’s disease a...

 1428

Neural reactivation supports memory formation when events end

Neural reactivation supports memory formation when...

 24

A language network in the individualized functional connectomes of 1199 human brains doing arbitrary tasks

A language network in the individualized functiona...

 38

Hyocholic acids shape neonatal immune tolerance and microbiota assembly

Hyocholic acids shape neonatal immune tolerance an...

 25

Emerging therapeutic opportunities targeting nonclassical MHC-I molecules

Emerging therapeutic opportunities targeting noncl...

 27

Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency

Genome-wide CRISPR screening identifies cellular f...

 22

RNA polymerase inhibitors reveal active-site motions essential for the nucleotide addition cycle

RNA polymerase inhibitors reveal active-site motio...

 19

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across enti...

 16

A molecular cell atlas of endocrine signaling in human neural organoids

A molecular cell atlas of endocrine signaling in h...

 27

A compendium of next-generation patient-derived models for diverse cancers

A compendium of next-generation patient-derived mo...

 60

High-resolution promoter interaction analysis implicates genes involved in activation of type 3 innate lymphoid cells in immune disease risk

High-resolution promoter interaction analysis impl...

 59

A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes

A reproducible three-dimensional model of human br...

 47

Mapping glioblastoma’s isoform diversity using long-read single-cell analysis

Mapping glioblastoma’s isoform diversity using lon...

 4642

Engineering and characterization of small- molecule transporters for cell factories

Engineering and characterization of small- molecul...

 74

Multigram-scale stereoselective synthesis of neurosteroid isomers by gut microbial isolates using plant biomass-derived medium

Multigram-scale stereoselective synthesis of neuro...

 67

A xeno-free human iPSC-derived prostate organoid platform for multilineage differentiation and genetic manipulation

A xeno-free human iPSC-derived prostate organoid p...

 81

Biotechnologies based on the fungal bioluminescence pathway

Biotechnologies based on the fungal bioluminescenc...

 97

PeptiVerse: A unified platform for therapeutic peptide property prediction

PeptiVerse: A unified platform for therapeutic pep...

 104

A critical appraisal of base-resolution m6 A  profiling techniques

A critical appraisal of base-resolution m6 A prof...

 110

Optogenetic mimicry of drug action: Tools and models to dissect the dopamine-dependent core of addiction

Optogenetic mimicry of drug action: Tools and mode...

 114

Breeding of Cotton

Breeding of Cotton

 337

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 474

THALASSEMIA

THALASSEMIA

 648

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 627

NMDA RECEPTORS

NMDA RECEPTORS

 414

Neural Development

Neural Development

 404

Transcription Factors

Transcription Factors

 394

Interferons

Interferons

 342

RABIES

RABIES

 352

ANEMIA

ANEMIA

 340

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

 348

Migraine

Migraine

 277

Dementia

Dementia

 371

Oxidative Signaling in Plants

Oxidative Signaling in Plants

 64

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

 80

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 158178

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 1896

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 1592

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 6320

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 520

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 500

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 643

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 383

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 503

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 547

School Science

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Disease Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 489

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 582

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 528

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 858

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 629

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 552

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 686

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 572

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 577

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 518

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 517

APOE in Alzheimer’s

APOE in Alzheimer’s

 731

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 664

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 858

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 629

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 552

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 686

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 572

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 577

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 518

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 517

APOE in Alzheimer’s

APOE in Alzheimer’s

 731

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 664

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 523

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 672

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 459

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 489

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 582

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 528

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