Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

13544

Evolutionary Constraints on Total Energy Expenditure

Science Hangouts

Evolutionary Constraints on Total Energy Expenditure

56

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

Science Hangouts

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

55

Science News Highlights

Transcription elongation factors in diseases

News highlights

Transcription elongation factors in diseases

4

Spatiotemporally controlled lysosome-targeted protein degradation platforms

News highlights

Spatiotemporally controlled lysosome-targeted protein ...

13

Targeting mechanotransduction in barrier organs

News highlights

Targeting mechanotransduction in barrier organs

11

News

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

19

Cognitive decline in human aging from oligodendrocyte dysfunction

Cognitive decline in human aging from oligodendroc...

22

How social isolation drives alcohol consumption

How social isolation drives alcohol consumption

18

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

29

Why some people can fight infections better than others?

Why some people can fight infections better than o...

41

Mechanism to regulate chronic neuropathic pain identified!

Mechanism to regulate chronic neuropathic pain ide...

35

How the brain represents meaning across different languages

How the brain represents meaning across different ...

22

How chromosomes find their partners

How chromosomes find their partners

54

Brain’s language network remains intact in old age

Brain’s language network remains intact in old age

23

Sleep and exercise may protect memory after sleep deprivation

Sleep and exercise may protect memory after sleep ...

29

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

42

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

37

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

32

Cognitive decline in human aging from oligodendrocyte dysfunction

Cognitive decline in human aging from oligodendroc...

22

How social isolation drives alcohol consumption

How social isolation drives alcohol consumption

18

Mechanism to regulate chronic neuropathic pain identified!

Mechanism to regulate chronic neuropathic pain ide...

35

How the brain represents meaning across different languages

How the brain represents meaning across different ...

22

Brain’s language network remains intact in old age

Brain’s language network remains intact in old age

23

Sleep and exercise may protect memory after sleep deprivation

Sleep and exercise may protect memory after sleep ...

29

Compound lowering human blood marker slows ALS

Compound lowering human blood marker slows ALS

55

Rewiring of protein interaction networks by autism mutations

Rewiring of protein interaction networks by autism...

65

Two prefrontal-subcortical circuits decide whether we are in control

Two prefrontal-subcortical circuits decide whether...

67

Hippocampal neurogenesis is dysregulated in depression

Hippocampal neurogenesis is dysregulated in depres...

51

Low-frequency deep brain stimulation improves speech and swallowing after traumatic brain injury

Low-frequency deep brain stimulation improves spee...

57

Human model of childhood dementia from drug screen and AI

Human model of childhood dementia from drug screen...

59

How microglia exacerbate ALS

How microglia exacerbate ALS

65

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

29

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

43

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

42

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

39

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

53

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

57

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

56

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

55

Protecting cells from iron overload

Protecting cells from iron overload

73

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

71

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

66

Tumor-secreted protein promotes lung metastasis

Tumor-secreted protein promotes lung metastasis

51

Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients

Immune cell dysfunction, not absence, defines skin...

78

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

53

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

432

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

119

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

142

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

162

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

207

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

204

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

187

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

214

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

219

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

233

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

218

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

233

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

107

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

60

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

78

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

70

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

82

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

90

A foundation model for sleep identifies health risks

A foundation model for sleep identifies health risks

74

AI discovers variation in local brain aging and cognition across human adulthood

AI discovers variation in local brain aging and co...

95

AI tool miniaturize and modify proteins without sacrificing function

AI tool miniaturize and modify proteins without sa...

269

Structure of neuronal epilepsy linked protein unraveled!

Structure of neuronal epilepsy linked protein unra...

107

AI platform could speed peptide drug discovery

AI platform could speed peptide drug discovery

122

AI-designed proteins for imaging inside living cells

AI-designed proteins for imaging inside living cells

99

AI model creates functional CRISPR-like nucleases

AI model creates functional CRISPR-like nucleases

123

Protein-based data storage

Protein-based data storage

153

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

159

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

165

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

306

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

226

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

276

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

328

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

315

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

289

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

325

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

296

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

346

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

359

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

37

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

32

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

72

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

50

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

53

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

57

A novel 3D brain tissue model

A novel 3D brain tissue model

89

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

61

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

72

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

138

Reverting aged cells to stem cells

Reverting aged cells to stem cells

204

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

96

Mechanism linking inflammation and prevention of neuron formation identified!

Mechanism linking inflammation and prevention of n...

133

How chromosomes find their partners

How chromosomes find their partners

54

New gene activation tool!

New gene activation tool!

50

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

56

First complete marmoset genome

First complete marmoset genome

69

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

104

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

100

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

114

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

120

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

150

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

169

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

176

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

184

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

209

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

83

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

118

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

122

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

109

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

105

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

200

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

235

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

234

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

251

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

566

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

559

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

551

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

660

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

44

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

54

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

72

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

65

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

79

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

99

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

94

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

133

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

118

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

103

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

127

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

136

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

153

Postbiotics may boost female fertility

Postbiotics may boost female fertility

69

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

97

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

95

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

143

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

165

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

201

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

190

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

234

sncRNAs in sperm aging

sncRNAs in sperm aging

306

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

242

How reproductive organs form

How reproductive organs form

345

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

252

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

243

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

19

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

41

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

53

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

66

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

75

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

40

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

30

Hidden function of a protein to influence leukemia drug

Hidden function of a protein to influence leukemia...

37

How antibiotics work inhibiting RNA polymerase?

How antibiotics work inhibiting RNA polymerase?

56

Mitochondria act as sensors for essential iron molecule

Mitochondria act as sensors for essential iron mol...

64

Evaluating gut microbial and host proteins in health and disease

Evaluating gut microbial and host proteins in heal...

64

Role of Golgi complex in DNA repair control

Role of Golgi complex in DNA repair control

64

Developing potent polyene antifungals

Developing potent polyene antifungals

77

Methylation puts parasites in motion

Methylation puts parasites in motion

32

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

129

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

168

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

87

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

80

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

97

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

86

Fasting primes gut microbiome to improve intestinal recovery after radiation treatment

Fasting primes gut microbiome to improve intestina...

94

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

102

Structural insight into the mechanism of bacterial pili retraction

Structural insight into the mechanism of bacterial...

109

Microbiota’s hidden role in mosquito-borne disease

Microbiota’s hidden role in mosquito-borne disease

126

Colorectal cancer signature

Colorectal cancer signature

93

How bacteria use circadian clocks to colonize

How bacteria use circadian clocks to colonize

83

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

44

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

45

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

77

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

119

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

130

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

116

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

111

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

141

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

115

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

127

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

149

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

143

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

153

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

43

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

55

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

128

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

103

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

106

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

103

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

103

Cure for dry eye disease

Cure for dry eye disease

134

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

140

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

165

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

143

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

142

Nicotine Biosynthesis!

Nicotine Biosynthesis!

275

Why some people can fight infections better than others?

Why some people can fight infections better than o...

41

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

42

Gene circuits of human immunity

Gene circuits of human immunity

55

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

55

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

59

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

48

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

65

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

61

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

60

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

72

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

65

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

94

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

69

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

40

Air-permeable hydrogels!

Air-permeable hydrogels!

103

Temperature behaves differently in the cell

Temperature behaves differently in the cell

106

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

107

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

142

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

158

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

236

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

519

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

415

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

899

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

511

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

478

Printed skin to replace animal testing

Printed skin to replace animal testing

483

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

42

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

63

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

37

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

39

Viral RNA elements functional map!

Viral RNA elements functional map!

48

How proteins change shape and move

How proteins change shape and move

52

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

59

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

105

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

60

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

67

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

98

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

501

Molecular map of liver disease

Molecular map of liver disease

90

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

98

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

258

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

454

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

460

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

444

How the brain regulates emotions

How the brain regulates emotions

662

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

520

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

518

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

551

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

516

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

515

Link between dietary choices and brain health

Link between dietary choices and brain health

487

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

471

Research

Cell death in cancer

Cell death in cancer

6

Transcription elongation by RNA polymerase II: from regulatory complexity to disease

Transcription elongation by RNA polymerase II: fro...

53

Automated prototyping of genetic codes

Automated prototyping of genetic codes

12

Oligodendrocyte dysfunction in human age-related cognitive decline

Oligodendrocyte dysfunction in human age-related c...

16

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

24

Barrier organ mechanomedicine and therapeutic insights

Barrier organ mechanomedicine and therapeutic insi...

19

Social isolation recruits amygdala–medial prefrontal cortex projections to escalate alcohol drinking in male mice

Social isolation recruits amygdala–medial prefront...

1082

Signaling downstream of tumor–stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity

Signaling downstream of tumor–stroma interaction r...

47

Harnessing the lung microbiome for precision management of fibrotic lung disease

Harnessing the lung microbiome for precision manag...

22

HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections

HLA-II peptide-binding diversity shapes humoral im...

34

Defying inflammation-driven early-onset colorectal cancer: predict, prevent, and personalize

Defying inflammation-driven early-onset colorectal...

32

Platelet-derived and platelet secretome biotherapies for precision neuromedicine

Platelet-derived and platelet secretome biotherapi...

33

Meiotic pairing through barcode-like satellite DNA repeats

Meiotic pairing through barcode-like satellite DNA...

28

Cell death in cancer

Cell death in cancer

6

Transcription elongation by RNA polymerase II: from regulatory complexity to disease

Transcription elongation by RNA polymerase II: fro...

53

Oligodendrocyte dysfunction in human age-related cognitive decline

Oligodendrocyte dysfunction in human age-related c...

16

Barrier organ mechanomedicine and therapeutic insights

Barrier organ mechanomedicine and therapeutic insi...

19

Social isolation recruits amygdala–medial prefrontal cortex projections to escalate alcohol drinking in male mice

Social isolation recruits amygdala–medial prefront...

1082

Signaling downstream of tumor–stroma interaction regulates mucinous colorectal adenocarcinoma apicobasal polarity

Signaling downstream of tumor–stroma interaction r...

47

Harnessing the lung microbiome for precision management of fibrotic lung disease

Harnessing the lung microbiome for precision manag...

22

HLA-II peptide-binding diversity shapes humoral immune responses and susceptibility to infections

HLA-II peptide-binding diversity shapes humoral im...

34

Defying inflammation-driven early-onset colorectal cancer: predict, prevent, and personalize

Defying inflammation-driven early-onset colorectal...

32

Platelet-derived and platelet secretome biotherapies for precision neuromedicine

Platelet-derived and platelet secretome biotherapi...

33

Meiotic pairing through barcode-like satellite DNA repeats

Meiotic pairing through barcode-like satellite DNA...

28

Preserved topography, lateralization, selectivity, and functional connectivity of the language network in older brains

Preserved topography, lateralization, selectivity,...

27

Protecting episodic memory after sleep loss: Similar benefits of exercise and naps via distinct neural contributions

Protecting episodic memory after sleep loss: Simil...

27

Automated prototyping of genetic codes

Automated prototyping of genetic codes

12

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

24

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

44

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

35

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

45

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

2972

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

40

Drug screen and machine learning predict neuroprotective agents in a preclinical human model of childhood dementia

Drug screen and machine learning predict neuroprot...

44

Human brain organoids record the passage of time over multiple years

Human brain organoids record the passage of time o...

48

Temporal uncoupling of radial glia lineage progression in cortical organoids

Temporal uncoupling of radial glia lineage progres...

2636

Trans-regulatory gene mapping prioritizes disease drivers in asthma

Trans-regulatory gene mapping prioritizes disease ...

52

Voltage imaging of neurons distributed across entire brains of larval zebrafish

Voltage imaging of neurons distributed across enti...

722

A molecular cell atlas of endocrine signaling in human neural organoids

A molecular cell atlas of endocrine signaling in h...

63

Breeding of Cotton

Breeding of Cotton

386

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

546

THALASSEMIA

THALASSEMIA

698

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

681

NMDA RECEPTORS

430

Neural Development

Neural Development

418

Transcription Factors

Transcription Factors

411

Interferons

363

RABIES

371

ANEMIA

356

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

368

Migraine

289

Dementia

383

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

45

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

64

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

58

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

54

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

36

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIENCE IN RTT SYNDROME

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIE...

3109

Oxidative Signaling in Plants

Oxidative Signaling in Plants

94

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

118

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

159899

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1949

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1611

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

6607

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

531

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

501

Gestational diabetes therapeutics

Gestational diabetes therapeutics

597

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

541

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

872

Different types of Alzheimer's disease

Different types of Alzheimer's disease

639

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

573

Alzheimer’s therapeutics

Alzheimer’s therapeutics

698

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

584

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

590

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

530

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

530

APOE in Alzheimer’s

APOE in Alzheimer’s

745

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

679

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

872

Different types of Alzheimer's disease

Different types of Alzheimer's disease

639

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

573

Alzheimer’s therapeutics

Alzheimer’s therapeutics

698

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

584

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

590

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

530

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

530

APOE in Alzheimer’s

APOE in Alzheimer’s

745

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

679

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

539

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

688

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

471

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

501

Gestational diabetes therapeutics

Gestational diabetes therapeutics

597

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

541