Index - Sciencemission

Science Hangouts

Transcriptional control of Tumor Metabolic Adaptations

Science Hangouts

Transcriptional control of Tumor Metabolic Adaptations

5

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

Science Hangouts

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

21

How cells survive in the minutes following an injury

Science Hangouts

How cells survive in the minutes following an injury

3

Science News Highlights

Interpreting non-coding variants using BRAIN-MAGNET

News highlights

Interpreting non-coding variants using BRAIN-MAGNET

5

Structural insights into PRC2 function in development and disease

News highlights

Structural insights into PRC2 function in development ...

4

Human stem cell models to evaluate role of oligodendrocytes in ALS

News highlights

Human stem cell models to evaluate role of oligodendro...

8

News

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

60

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

5

How the brain decides what to remember

How the brain decides what to remember

24

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

25

How DNA is recognized by proteins that control gene expression

How DNA is recognized by proteins that control gen...

19

Cooperative motor proteins found to kill cancer cells when dual-inhibited

Cooperative motor proteins found to kill cancer ce...

25

Mapping the molecular blueprint of blood’s secret messengers

Mapping the molecular blueprint of blood’s secret ...

84

Medications change our gut microbiome in predictable ways

Medications change our gut microbiome in predictab...

45

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

36

How Hebbian learning explains our recall of past events

How Hebbian learning explains our recall of past e...

33

Mechanism of plasma membrane remodeling that drives mitotic cell rounding

Mechanism of plasma membrane remodeling that drive...

21

A new cell death pathway, mitoxyperilysis, from Inflammation and metabolic stress

A new cell death pathway, mitoxyperilysis, from In...

163

Cancer uses cell death proteins to survive treatment and regrow

Cancer uses cell death proteins to survive treatme...

28

How the brain decides what to remember

How the brain decides what to remember

24

How Hebbian learning explains our recall of past events

How Hebbian learning explains our recall of past e...

33

Blocking fructose metabolism to reduce alcohol cravings and liver damage

Blocking fructose metabolism to reduce alcohol cra...

75

Modulation of Alzheimer’s tau and Parkinson’s α-synuclein by spermine

Modulation of Alzheimer’s tau and Parkinson’s α-sy...

62

Tabletop blast device to study traumatic brain injury

Tabletop blast device to study traumatic brain injury

37

ALS treatment using RNA-based gene therapy

ALS treatment using RNA-based gene therapy

44

Environmental stiffness regulates neuronal maturation

Environmental stiffness regulates neuronal maturation

24

Biliverdin reductase A (BVRA) protects brain from oxidative stress damage

Biliverdin reductase A (BVRA) protects brain from ...

54

Free radicals in the brain that may fuel dementia

Free radicals in the brain that may fuel dementia

97

Intestinal enzyme FMO-2 regulates behavior

Intestinal enzyme FMO-2 regulates behavior

93

Microglia expressing lymphoid genes are neuroprotective

Microglia expressing lymphoid genes are neuroprote...

43

Where language comes from?

Where language comes from?

33

A new on-switch for pain signaling pathway

A new on-switch for pain signaling pathway

60

Cooperative motor proteins found to kill cancer cells when dual-inhibited

Cooperative motor proteins found to kill cancer ce...

25

Mechanism of plasma membrane remodeling that drives mitotic cell rounding

Mechanism of plasma membrane remodeling that drive...

21

Cancer uses cell death proteins to survive treatment and regrow

Cancer uses cell death proteins to survive treatme...

28

How some BRCA1 variants are hidden?

How some BRCA1 variants are hidden?

39

Inflammation rewires bone marrow microenvironment long before leukaemias develop

Inflammation rewires bone marrow microenvironment ...

43

Eliminating cancer by harnessing tumor cell signaling

Eliminating cancer by harnessing tumor cell signaling

73

Leukemia mutations in nuclear droplets!

Leukemia mutations in nuclear droplets!

49

Blocking key protein triggers cancer cell self-destruction

Blocking key protein triggers cancer cell self-de...

50

Promising drug for aggressive breast cancer

Promising drug for aggressive breast cancer

60

How controlling sunburn-triggered inflammation may prevent skin cancer

How controlling sunburn-triggered inflammation may...

67

Controlling cancer drug response by regulating purine biosynthesis

Controlling cancer drug response by regulating pur...

59

A novel mechanism behind breast cancer chemoresistance discovered

A novel mechanism behind breast cancer chemoresist...

69

RNA mediated lipid droplet gene hub for cancer progression

RNA mediated lipid droplet gene hub for cancer pro...

61

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

60

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

5

Mitochondrial ketone body oxidation impaired in diabetes & liver disease

Mitochondrial ketone body oxidation impaired in di...

67

Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

Sons of mothers with type 1 diabetes show early si...

31

Aged blood vessel cells drive metabolic diseases

Aged blood vessel cells drive metabolic diseases

80

Genes associated with obesity shared across ancestries

Genes associated with obesity shared across ancest...

62

A muscle specific protein reduces high ketone levels in diabetic patients

A muscle specific protein reduces high ketone leve...

53

Genetic variants controlling body weight

Genetic variants controlling body weight

81

Role of nuclear hormone-sensitive lipase (HSL) in lipid metabolism

Role of nuclear hormone-sensitive lipase (HSL) in ...

62

Glycation-lowering compounds curb hunger, lower insulin resistance and extend lifespan

Glycation-lowering compounds curb hunger, lower in...

208

Gene converts insulin-producing cells into blood-sugar boosters

Gene converts insulin-producing cells into blood-s...

122

Key mechanism for appetite and weight control

Key mechanism for appetite and weight control

106

Macrophages protect insulin production in pancreas

Macrophages protect insulin production in pancreas

107

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

25

AI model to detect skin cancer

AI model to detect skin cancer

35

AI Uncovers Genetic Architecture of the Human Corpus Callosum

AI Uncovers Genetic Architecture of the Human Corp...

77

AI can speed antibody design

AI can speed antibody design

76

AI generative models reveal the cortical representation of dancing

AI generative models reveal the cortical represent...

33

AI based biophysical models of neural dynamics

AI based biophysical models of neural dynamics

56

Human Replication Protein A complex is Essential for Telomere Maintenance

Human Replication Protein A complex is Essential f...

44

Amino acids play a key role in brain's G protein signaling

Amino acids play a key role in brain's G protein ...

95

AI-tool for 3D cell analysis

AI-tool for 3D cell analysis

82

Neural mechanisms behind cooperation

Neural mechanisms behind cooperation

95

A human pan-disease blood atlas of the circulating proteome

A human pan-disease blood atlas of the circulating...

303

A language model for enhanced lasso peptide property prediction

A language model for enhanced lasso peptide proper...

66

AI model to build one of the most detailed mouse brain maps

AI model to build one of the most detailed mouse b...

77

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

66

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

38

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

69

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

99

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

73

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

103

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

136

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

100

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

284

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

263

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

360

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

498

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

353

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

23

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

55

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

53

How hair stem cells under stress make decisions to graying or melanoma

How hair stem cells under stress make decisions to...

66

A cysteine-rich diet may promote regeneration of the intestinal lining

A cysteine-rich diet may promote regeneration of t...

72

Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice

Stem cell transplant for stroke leads to brain cel...

83

Stem cell models show epilepsy genes disrupt different brain regions

Stem cell models show epilepsy genes disrupt diffe...

87

Ureteral organoid from pluripotent stem cells

Ureteral organoid from pluripotent stem cells

78

Progenitor neighborhood signaling in neurogenesis

Progenitor neighborhood signaling in neurogenesis

79

Evolutionary changes in the developing human intestine

Evolutionary changes in the developing human intes...

255

Human kidney organoids from stem cells

Human kidney organoids from stem cells

250

Human bone marrow stem cell metabolism altered by aging and cancer

Human bone marrow stem cell metabolism altered by ...

279

Serine deprivation switches hair follicle stem cells into skin healers during injury

Serine deprivation switches hair follicle stem cel...

261

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

62

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

56

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

75

A genome-to-proteome map

A genome-to-proteome map

85

Why naked mole-rats live longer

Why naked mole-rats live longer

53

Gene therapy for alpha thalassemia major

Gene therapy for alpha thalassemia major

97

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

112

Genetic test predicts obesity in childhood

Genetic test predicts obesity in childhood

232

Analysis of India's genetic diversity

Analysis of India's genetic diversity

253

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

363

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

340

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

334

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

337

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

25

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

71

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

364

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

380

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

356

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

367

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

249

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

336

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

361

Role of ECM in brain memory

Role of ECM in brain memory

338

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

351

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

346

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

344

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

35

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

65

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

40

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

53

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

90

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

155

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

240

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

306

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

543

Key mechanism of brain repair in vascular dementia

Key mechanism of brain repair in vascular dementia

250

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

283

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

300

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

315

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

38

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

66

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

120

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

81

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

55

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

58

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

68

Functional eggs from human skin cells

Functional eggs from human skin cells

66

Sperm microRNAs regulate paternal transmission of exercise capacity

Sperm microRNAs regulate paternal transmission of ...

73

How sperm achieves energy demands for fertilization

How sperm achieves energy demands for fertilization

87

Why does female fertility decline with age?

Why does female fertility decline with age?

59

Trophoblast differentiation in 3D bioprinted miniature placentas

Trophoblast differentiation in 3D bioprinted minia...

66

Inflammatory diseases in the offspring from mothers food additive consumption during pregnancy

Inflammatory diseases in the offspring from mother...

66

How DNA is recognized by proteins that control gene expression

How DNA is recognized by proteins that control gen...

19

A new cell death pathway, mitoxyperilysis, from Inflammation and metabolic stress

A new cell death pathway, mitoxyperilysis, from In...

163

What regulates epigenetics?

What regulates epigenetics?

65

How cells orchestrate protein production

How cells orchestrate protein production

52

Protein droplets in the nucleus guard against cancer

Protein droplets in the nucleus guard against cancer

31

A ‘hidden pocket’ to target nuclear receptors

A ‘hidden pocket’ to target nuclear receptors

64

Direct targeting and regulation of RNA polymerase II by cell signaling kinases

Direct targeting and regulation of RNA polymerase ...

76

Saving cells from the brink of death

Saving cells from the brink of death

79

‘Traffic controller’ protein protects DNA, and may kill cancer cells

‘Traffic controller’ protein protects DNA, and ma...

45

Self-cleavage as built-in quality control

Self-cleavage as built-in quality control

75

Protein condensates determine a cell’s fate

Protein condensates determine a cell’s fate

103

RNA splitting mechanism behind origin of Type V CRISPR systems

RNA splitting mechanism behind origin of Type V CR...

59

A ubiquitin precursor promotes stress resistance and longevity

A ubiquitin precursor promotes stress resistance ...

71

Medications change our gut microbiome in predictable ways

Medications change our gut microbiome in predictab...

45

Blood-based immunological signatures for extrapulmonary tuberculosis

Blood-based immunological signatures for extrapulm...

26

How human astroviruses bind to humans cells?

How human astroviruses bind to humans cells?

38

Rebalancing lung repair with immune damage is key to surviving severe influenza

Rebalancing lung repair with immune damage is key ...

34

Toxic gut bacteria may drive ulcerative colitis

Toxic gut bacteria may drive ulcerative colitis

47

Missing nutrient in HIV mothers milk pose health challenges in children

Missing nutrient in HIV mothers milk pose health c...

30

How bacteria that cause inflammatory colitis outmaneuver our body’s defenses

How bacteria that cause inflammatory colitis outma...

41

New mechanism for tick born viral entry into human cells

New mechanism for tick born viral entry into human...

42

Serotonin producing human microbiota identified!

Serotonin producing human microbiota identified!

775

Vitamin D levels fell during COVID-19 pandemic

Vitamin D levels fell during COVID-19 pandemic

83

HIV-1 integrase structure revealed!

HIV-1 integrase structure revealed!

85

Dangerous E. coli strain blocks gut’s defense mechanism to spread infection

Dangerous E. coli strain blocks gut’s defense mech...

54

Discovery of hundreds of new human gut viruses

Discovery of hundreds of new human gut viruses

152

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

82

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

70

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

70

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

75

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

154

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

229

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

263

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

269

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

246

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

267

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

387

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

329

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

374

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

33

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

130

How cucumbers got longer?

How cucumbers got longer?

91

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

45

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

60

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

58

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

117

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

329

How plants sense heat during the day

How plants sense heat during the day

300

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

263

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

309

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

318

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

341

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

36

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

76

Oxygen deprivation drives dysfunctional neutrophil immunity

Oxygen deprivation drives dysfunctional neutrophil...

75

Psoriasis-linked gene mutation also impacts gut health

Psoriasis-linked gene mutation also impacts gut he...

67

‘Unconventional’ immune cells to tackle inflammation in the gut

‘Unconventional’ immune cells to tackle inflammati...

75

Predicting if multiple sclerosis medication will be effective for patients

Predicting if multiple sclerosis medication will b...

86

‘Creeping fat’ can worsen Crohn’s disease

‘Creeping fat’ can worsen Crohn’s disease

82

Healthy telomeres key for cancer-fighting T cells

Healthy telomeres key for cancer-fighting T cells

127

Cellular “toolkit” to reprogram immune cells for cancer therapy

Cellular “toolkit” to reprogram immune cells for c...

134

New monoclonal antibody targets deadly sepsis

New monoclonal antibody targets deadly sepsis

94

How cells in small intestine of people with coeliac disease communicate with one another

How cells in small intestine of people with coelia...

172

Gut neurons help the body fight inflammation

Gut neurons help the body fight inflammation

190

Breast milk maternal antibodies regulate early neonatal immune responses in mouse gut

Breast milk maternal antibodies regulate early neo...

217

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

325

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

224

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

673

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

298

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

288

Printed skin to replace animal testing

Printed skin to replace animal testing

303

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

280

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

297

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

312

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

335

Mapping the molecular blueprint of blood’s secret messengers

Mapping the molecular blueprint of blood’s secret ...

84

CRISPR editing in nondividing human cells (neurons)

CRISPR editing in nondividing human cells (neurons)

53

New method offers broader and faster detection of protein-ligand interactions

New method offers broader and faster detection of ...

53

Structural basis of apoptosis induction

Structural basis of apoptosis induction

47

Cryo-EM structure of yellow fever virus

Cryo-EM structure of yellow fever virus

37

A new atlas of the human brain

A new atlas of the human brain

59

Simple method for viewing microscopic fibers

Simple method for viewing microscopic fibers

35

New CRISPR platform to expose concealed metastasis regulators

New CRISPR platform to expose concealed metastasis...

62

Imaging microvasculature of an entire organ using ultrasound in 4D

Imaging microvasculature of an entire organ using ...

33

New dry macular degeneration treatment

New dry macular degeneration treatment

18

Spatial biology to visualize chemical signals of individual cells

Spatial biology to visualize chemical signals of i...

37

Identification of antimalarial target binding partner

Identification of antimalarial target binding partner

58

Algorithm maps genetic connection between Alzheimer’s and specific neurons

Algorithm maps genetic connection between Alzheime...

59

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

66

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

263

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

250

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

264

How the brain regulates emotions

How the brain regulates emotions

345

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

336

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

326

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

373

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

340

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

353

Link between dietary choices and brain health

Link between dietary choices and brain health

328

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

244

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

387

Research

Portal vein-enriched metabolites as intermediate regulators of the gut microbiome in insulin resistance

Portal vein-enriched metabolites as intermediate r...

22

BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants

BRAIN-MAGNET: A functional genomics atlas for inte...

8

Cryo-electron microscopy reveals sequential binding and activation of Ryanodine Receptors by statin triplets

Cryo-electron microscopy reveals sequential bindin...

4

Inhibitors supercharge kinase turnover through native proteolytic circuits

Inhibitors supercharge kinase turnover through nat...

8

Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells

Thermodynamic principles link in vitro transcripti...

9

Emerging structural insights into PRC2 function in development and disease

Emerging structural insights into PRC2 function in...

17

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C

KIF18A promotes chromosome congression in cooperat...

11

Multi-omics identify hallmark protein and lipid features of small extracellular vesicles circulating in human plasma

Multi-omics identify hallmark protein and lipid fe...

37

Revisiting oligodendrocytes in amyotrophic lateral sclerosis using human multicellular stem cell models

Revisiting oligodendrocytes in amyotrophic lateral...

19

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis

Metabolic environment-driven remodeling of mitocho...

42

Homeostasis of megakaryocytes: balancing tissue residency and consumptive platelet production

Homeostasis of megakaryocytes: balancing tissue re...

14

Approaches for identification of 5′ UTR mutations impacting translation and protein production from neurodevelopmental disorder genes

Approaches for identification of 5′ UTR mutations ...

961

Diverse perceptual biases emerge from Hebbian plasticity in a recurrent neural network model

Diverse perceptual biases emerge from Hebbian plas...

15

Portal vein-enriched metabolites as intermediate regulators of the gut microbiome in insulin resistance

Portal vein-enriched metabolites as intermediate r...

22

Cryo-electron microscopy reveals sequential binding and activation of Ryanodine Receptors by statin triplets

Cryo-electron microscopy reveals sequential bindin...

4

Inhibitors supercharge kinase turnover through native proteolytic circuits

Inhibitors supercharge kinase turnover through nat...

8

Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells

Thermodynamic principles link in vitro transcripti...

9

Emerging structural insights into PRC2 function in development and disease

Emerging structural insights into PRC2 function in...

17

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C

KIF18A promotes chromosome congression in cooperat...

11

Multi-omics identify hallmark protein and lipid features of small extracellular vesicles circulating in human plasma

Multi-omics identify hallmark protein and lipid fe...

37

Revisiting oligodendrocytes in amyotrophic lateral sclerosis using human multicellular stem cell models

Revisiting oligodendrocytes in amyotrophic lateral...

19

Metabolic environment-driven remodeling of mitochondrial ribosomes regulates translation and biogenesis

Metabolic environment-driven remodeling of mitocho...

42

Homeostasis of megakaryocytes: balancing tissue residency and consumptive platelet production

Homeostasis of megakaryocytes: balancing tissue re...

14

Diverse perceptual biases emerge from Hebbian plasticity in a recurrent neural network model

Diverse perceptual biases emerge from Hebbian plas...

15

DNA fragmentation factor B suppresses interferon to enable cancer persister cell regrowth

DNA fragmentation factor B suppresses interferon t...

23

Curing autoimmune diabetes in mice with islet and hematopoietic cell transplantation after CD117 antibody-based conditioning

Curing autoimmune diabetes in mice with islet and ...

19

BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants

BRAIN-MAGNET: A functional genomics atlas for inte...

8

Approaches for identification of 5′ UTR mutations impacting translation and protein production from neurodevelopmental disorder genes

Approaches for identification of 5′ UTR mutations ...

961

Characterizing and controlling CRISPR repair outcomes in nondividing human cells

Characterizing and controlling CRISPR repair outco...

27

Generation of human nucleus basalis organoids with functional nbM-cortical cholinergic projections in transplanted assembloids

Generation of human nucleus basalis organoids with...

31

A tabletop blast device for the study of the long-term consequences of traumatic brain injury on brain organoids

A tabletop blast device for the study of the long-...

21

High-throughput peptide-centric local stability assay extends protein–ligand identification to membrane proteins, tissues and bacteria

High-throughput peptide-centric local stability as...

23

Digital twins for in vivo metabolic flux estimations in patients with brain cancer

Digital twins for in vivo metabolic flux estimatio...

32

Monitoring the complexity and dynamics of mitochondrial translation

Monitoring the complexity and dynamics of mitochon...

51

Micron-resolution fiber mapping in histology independent of sample preparation

Micron-resolution fiber mapping in histology indep...

29

Visual detection of seizures in mice using supervised machine learning

Visual detection of seizures in mice using supervi...

33

Jaxley: differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics

Jaxley: differentiable simulation enables large-sc...

106

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases

The Neurolipid Atlas: a lipidomics resource for ne...

100

Spatial biology using single-cell mass spectrometry imaging and integrated microscopy

Spatial biology using single-cell mass spectrometr...

48

Diabetic Neuropathy

Diabetic Neuropathy

28

Neural Transmission

Neural Transmission

55

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

65

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

270

Potassium Channels

Potassium Channels

128

Calcium channels physiology and Therapeutics uses

Calcium channels physiology and Therapeutics uses

169

Cell Signaling and Communication between Cells

Cell Signaling and Communication between Cells

412

Humoral Immunity

Humoral Immunity

90

Cell Mediated Immunity

Cell Mediated Immunity

249

Telomere

97

What is Asthma

85

Tuberculosis

102

Anemia

146

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

48709

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1059

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

992

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

2540

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

336

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

328

HEAD AND NECK CANCER

HEAD AND NECK CANCER

346

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

192

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

319

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

357

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

301

Gestational diabetes therapeutics

Gestational diabetes therapeutics

296

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

321

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

488

Different types of Alzheimer's disease

Different types of Alzheimer's disease

390

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

342

Alzheimer’s therapeutics

Alzheimer’s therapeutics

349

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

331

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

365

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

309

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

336

APOE in Alzheimer’s

APOE in Alzheimer’s

395

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

465

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

488

Different types of Alzheimer's disease

Different types of Alzheimer's disease

390

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

342

Alzheimer’s therapeutics

Alzheimer’s therapeutics

349

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

331

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

365

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

309

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

336

APOE in Alzheimer’s

APOE in Alzheimer’s

395

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

465

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

329

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

361

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

297

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

301

Gestational diabetes therapeutics

Gestational diabetes therapeutics

296

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

321