Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

5556

Spread of pathology in neurodegenerative diseases: mechanisms and implications

Science Hangouts

Spread of pathology in neurodegenerative diseases: mechanisms and implications

105

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

Science Hangouts

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

106

Science News Highlights

Inhibiting CDC42 subfamily to treat diseases

News highlights

Inhibiting CDC42 subfamily to treat diseases

5

Metabolic dysfunction from heat stress via skin-hypothalamus axis

News highlights

Metabolic dysfunction from heat stress via skin-hypoth...

7

Celastrol prevents aging-related sarcopenia and mitochondrial dysfunction

News highlights

Celastrol prevents aging-related sarcopenia and mitoch...

8

News

Cure for dry eye disease

Cure for dry eye disease

7

Zinc finger proteins act on gene promoters to control differentiation of stem cells

Zinc finger proteins act on gene promoters to cont...

19

Peripheral-to-central immune infiltration and reprogramming in ALS

Peripheral-to-central immune infiltration and repr...

26

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

23

Preventing uptake of alpha-synuclein to slow Parkinson’s progression

Preventing uptake of alpha-synuclein to slow Parki...

47

Selective degradation of proteins involved in pathological processes

Selective degradation of proteins involved in path...

40

Surprising cellular dynamics of the aging brain

Surprising cellular dynamics of the aging brain

71

Depression dampens anticipation, not enjoyment

Depression dampens anticipation, not enjoyment

42

HIV-1 remodels nuclear pores to infect immune cells

HIV-1 remodels nuclear pores to infect immune cells

44

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

58

New CRISPR tool eliminates undesired cells

New CRISPR tool eliminates undesired cells

46

Multiplexed MRI provides a comprehensive view of the human brain

Multiplexed MRI provides a comprehensive view of t...

49

A new kind of cold sensor

A new kind of cold sensor

43

Peripheral-to-central immune infiltration and reprogramming in ALS

Peripheral-to-central immune infiltration and repr...

26

Preventing uptake of alpha-synuclein to slow Parkinson’s progression

Preventing uptake of alpha-synuclein to slow Parki...

47

Depression dampens anticipation, not enjoyment

Depression dampens anticipation, not enjoyment

42

Can dopamine bend time to shape memory?

Can dopamine bend time to shape memory?

33

Functional MRI identifies the direction of neural signals

Functional MRI identifies the direction of neural ...

44

Garlic-derived compound acts via fat-brain-muscle circuit to improve muscle health during aging

Garlic-derived compound acts via fat-brain-muscle ...

64

Early disruption of molecular and cellular processes in Down syndrome

Early disruption of molecular and cellular process...

35

Mechanism of antidepressant effect of transcranial magnetic stimulation

Mechanism of antidepressant effect of transcranial...

42

Smell receptors mapped!

Smell receptors mapped!

23

Skin nerves can slow melanoma growth

Skin nerves can slow melanoma growth

39

Can we dream while awake?

Can we dream while awake?

40

Identifying genetic causes of blindness in people and macaques

Identifying genetic causes of blindness in people ...

42

New experimental drug may restore movement after stroke

New experimental drug may restore movement after s...

60

Selective degradation of proteins involved in pathological processes

Selective degradation of proteins involved in path...

40

Testosterone slows brain tumor growth

Testosterone slows brain tumor growth

48

How an enzyme affects infertility and cancer progression

How an enzyme affects infertility and cancer progr...

40

How gut bacteria toxin invades colon cells to trigger cancer

How gut bacteria toxin invades colon cells to trig...

43

New method reveals tumor environment that favor metastatic growth

New method reveals tumor environment that favor me...

69

Developing tumor microenvironment for cancer growth

Developing tumor microenvironment for cancer growth

55

Which breast lesions will progress to cancer?

Which breast lesions will progress to cancer?

57

A key regulator of metastatic potential in breast cancer tumors identified!

A key regulator of metastatic potential in breast ...

55

Dynamic interactions between brain tumors and immune cells

Dynamic interactions between brain tumors and immu...

65

Protein interactions in childhood brain cancer

Protein interactions in childhood brain cancer

72

Flipping the switch from benign growth to pancreatic cancer

Flipping the switch from benign growth to pancreat...

60

A gene regulatory protein identified as a novel dependency in cancers

A gene regulatory protein identified as a novel de...

67

Urine liquid biopsy for bladder cancer

Urine liquid biopsy for bladder cancer

64

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

58

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

69

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

59

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

75

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

88

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

102

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

91

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

91

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

106

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

122

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

212

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

128

Human islet cell electrical maturation

Human islet cell electrical maturation

128

FaceAge AI tool predicts cancer patients survival

FaceAge AI tool predicts cancer patients survival

31

A potassium-gated ion channel identified!

A potassium-gated ion channel identified!

60

AI model for protein-protein interaction modeling

AI model for protein-protein interaction modeling

80

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

118

Gene signature predicting lung cancer recurrence

Gene signature predicting lung cancer recurrence

91

Bio-bank data analysis links genetics to disease risk and treatment response

Bio-bank data analysis links genetics to disease r...

92

Computational model measures telomere shortening from routine biopsies

Computational model measures telomere shortening f...

84

AI tool to predict heart diseases 15 years in advance

AI tool to predict heart diseases 15 years in advance

94

Artificial intelligence decodes tissue characteristics of type 2 diabetes

Artificial intelligence decodes tissue characteris...

102

Rapid Evolution of Complex Multi-mutant Proteins

Rapid Evolution of Complex Multi-mutant Proteins

135

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

142

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

123

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

162

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

41

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

154

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

107

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

139

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

193

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

180

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

177

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

216

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

189

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

227

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

240

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

213

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

405

Zinc finger proteins act on gene promoters to control differentiation of stem cells

Zinc finger proteins act on gene promoters to cont...

19

Identifying the ‘organizer’ cells that build bone marrow

Identifying the ‘organizer’ cells that build bone ...

44

Not all Alzheimer’s leads to dementia

Not all Alzheimer’s leads to dementia

65

What keeps vision cells alive?

What keeps vision cells alive?

108

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

75

A long-term and scalable system to record from neural organoids

A long-term and scalable system to record from neu...

77

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

106

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

116

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

127

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

255

How cell walls guide stem cells

How cell walls guide stem cells

141

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

148

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

141

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

51

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

79

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

77

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

97

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

101

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

90

How longevity is inherited across generations

How longevity is inherited across generations

160

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

112

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

143

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

120

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

103

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

145

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

121

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

96

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

130

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

141

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

168

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

462

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

472

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

460

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

519

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

361

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

431

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

552

Role of ECM in brain memory

Role of ECM in brain memory

480

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

487

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

44

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

38

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

66

Mechanisms of aortic aneurysm progression

Mechanisms of aortic aneurysm progression

42

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

131

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

95

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

113

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

100

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

113

A novel inflammatory function of platelets

A novel inflammatory function of platelets

128

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

132

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

148

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

130

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

40

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

76

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

93

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

94

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

126

sncRNAs in sperm aging

sncRNAs in sperm aging

123

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

158

How reproductive organs form

How reproductive organs form

158

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

150

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

149

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

185

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

229

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

185

A new kind of cold sensor

A new kind of cold sensor

43

Childhood brain diseases from mutations in tubulin co-factors

Childhood brain diseases from mutations in tubulin...

37

Zinc-Redox crosstalk to control protein quality

Zinc-Redox crosstalk to control protein quality

40

New mechanisms of oncogenic fusion protein activation and signaling

New mechanisms of oncogenic fusion protein activat...

47

Gene circuits reshape DNA folding and affect how genes are expressed

Gene circuits reshape DNA folding and affect how g...

56

Maternal fatty acid is associated with childhood asthma

Maternal fatty acid is associated with childhood a...

65

Water molecules drive gene transcription process

Water molecules drive gene transcription process

34

How cells turn mechanical forces into biochemical signals

How cells turn mechanical forces into biochemical ...

52

Naturally occurring molecule can stop Alzheimer’s-linked fibrils from forming

Naturally occurring molecule can stop Alzheimer’s-...

43

Structure of binding pocket of TRPM3 ion channel linked to pain signaling and epilepsy

Structure of binding pocket of TRPM3 ion channel l...

68

New method reveals structures of RNA-protein complexes in living cells

New method reveals structures of RNA-protein compl...

98

Protein helps cells handle stress

Protein helps cells handle stress

71

The antioxidant glutathione plays a key role in protein folding

The antioxidant glutathione plays a key role in pr...

79

HIV-1 remodels nuclear pores to infect immune cells

HIV-1 remodels nuclear pores to infect immune cells

44

Myocarditis after mRNA vaccination is attributed to mitochondrial stress

Myocarditis after mRNA vaccination is attributed t...

43

Engineered bacteria to treat liver-related brain dysfunction

Engineered bacteria to treat liver-related brain d...

59

How pathogens switch on their virulence

How pathogens switch on their virulence

44

Disease-causing pathogen rewires gut metabolism to grow

Disease-causing pathogen rewires gut metabolism to...

51

Pro- and anti-HIV host factors in T cells

Pro- and anti-HIV host factors in T cells

52

A new way coronaviruses can get into human cells

A new way coronaviruses can get into human cells

56

How caspofungin inhibits fungal infection?

How caspofungin inhibits fungal infection?

51

Cell proteins that drive severe viral infections identified

Cell proteins that drive severe viral infections i...

66

Oral-gut axis microbiome biomarkers for early gastric cancer detection

Oral-gut axis microbiome biomarkers for early gast...

53

How parasites exit host cells

How parasites exit host cells

78

Gut–brain signalling in parasite infection

Gut–brain signalling in parasite infection

93

How bacteria drive chronic kidney disease progression

How bacteria drive chronic kidney disease progression

119

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

60

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

38

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

43

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

63

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

68

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

74

A developmental atlas for genes and cells

A developmental atlas for genes and cells

99

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

120

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

100

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

193

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

174

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

181

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

203

Cure for dry eye disease

Cure for dry eye disease

7

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

23

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

70

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

59

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

61

Nicotine Biosynthesis!

Nicotine Biosynthesis!

93

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

85

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

125

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

81

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

89

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

152

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

242

How cucumbers got longer?

How cucumbers got longer?

232

A key protein in the inflammatory response to infections identified

A key protein in the inflammatory response to infe...

43

Proper protein recycling helps exhausted immune cells fight tumors

Proper protein recycling helps exhausted immune ce...

54

How immune cell networks drive liver disease

How immune cell networks drive liver disease

61

NO-independent inflammatory response by iNOS

NO-independent inflammatory response by iNOS

56

Stromal-immune cell circuit in human lymph nodes

Stromal-immune cell circuit in human lymph nodes

77

Mitochondria keep immune cells “ready to respond”

Mitochondria keep immune cells “ready to respond”

74

How the immune system rewrites rapid aging

How the immune system rewrites rapid aging

70

Mutations in immune cells linked to autoimmune diseases

Mutations in immune cells linked to autoimmune dis...

78

Making cancer cells more visible to immune system

Making cancer cells more visible to immune system

72

Stem cell gene editing to produce B cell protein factories

Stem cell gene editing to produce B cell protein f...

74

The female immune system changes much more than that of men with age

The female immune system changes much more than th...

91

High‑fat diets linked to rapid decline in protective gut immune cells

High‑fat diets linked to rapid decline in protecti...

118

How key immune cells protect the prostate

How key immune cells protect the prostate

60

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

27

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

66

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

67

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

150

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

434

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

333

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

788

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

415

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

401

Printed skin to replace animal testing

Printed skin to replace animal testing

405

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

385

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

407

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

430

Surprising cellular dynamics of the aging brain

Surprising cellular dynamics of the aging brain

71

New CRISPR tool eliminates undesired cells

New CRISPR tool eliminates undesired cells

46

Multiplexed MRI provides a comprehensive view of the human brain

Multiplexed MRI provides a comprehensive view of t...

49

“Aging clocks” to measure body decline

“Aging clocks” to measure body decline

35

“MitoCatch” delivers healthy mitochondria to diseased cells

“MitoCatch” delivers healthy mitochondria to disea...

114

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

79

How the body senses cold

How the body senses cold

124

New computational biology for genome sequencing analysis

New computational biology for genome sequencing an...

102

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

107

Glycoprotein heterodimers on nanoparticles for hepatitis C virus vaccine design

Glycoprotein heterodimers on nanoparticles for hep...

89

Assay to analyze regulatory function and epigenomic modifications simultaneously

Assay to analyze regulatory function and epigenomi...

97

Peptide ligase–mediated display

Peptide ligase–mediated display

115

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

161

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

171

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

364

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

361

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

363

How the brain regulates emotions

How the brain regulates emotions

482

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

433

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

422

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

468

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

433

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

439

Link between dietary choices and brain health

Link between dietary choices and brain health

409

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

372

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

493

Research

Transplanting light-dependent reactions for mammalian eye photosynthesis

Transplanting light-dependent reactions for mammal...

2

Recent advances in CDC42 subfamily inhibition and therapeutic potential

Recent advances in CDC42 subfamily inhibition and ...

10

A skin-hypothalamus axis couples heat stress and metabolic dysfunction

A skin-hypothalamus axis couples heat stress and m...

15

In silico transcriptome-based drug screening identifies celastrol as a multi-species therapeutic agent against aging-related sarcopenia and mitochondrial dysfunction

In silico transcriptome-based drug screening ident...

26

RLF/ZFP292 stabilize CoREST-linked LSD1 engagement at bivalent promoters to safeguard pluripotency

RLF/ZFP292 stabilize CoREST-linked LSD1 engagement...

12

Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming

Integrated single-cell and spatial transcriptomic ...

18

Beneficial microbes in agriculture: curse or blessing?

Beneficial microbes in agriculture: curse or bless...

25

White matter lesions disrupt cholinergic pathways important for cognition in Parkinson’s disease

White matter lesions disrupt cholinergic pathways ...

29

Molecular and therapeutic frontiers in anemia therapy

Molecular and therapeutic frontiers in anemia therapy

43

Toward mutational epidemiology: using mutational signatures of environmental exposures to assess cancer risk

Toward mutational epidemiology: using mutational s...

26

Secreted GPNMB enhances uptake of fibrillar alpha- synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies

Secreted GPNMB enhances uptake of fibrillar alpha-...

22

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome

Expanding the targeted protein degradation approac...

28

Optics-free spatial genomics for mapping mammalian brain aging by IRISeq

Optics-free spatial genomics for mapping mammalian...

23

Transplanting light-dependent reactions for mammalian eye photosynthesis

Transplanting light-dependent reactions for mammal...

2

Recent advances in CDC42 subfamily inhibition and therapeutic potential

Recent advances in CDC42 subfamily inhibition and ...

10

A skin-hypothalamus axis couples heat stress and metabolic dysfunction

A skin-hypothalamus axis couples heat stress and m...

15

In silico transcriptome-based drug screening identifies celastrol as a multi-species therapeutic agent against aging-related sarcopenia and mitochondrial dysfunction

In silico transcriptome-based drug screening ident...

26

RLF/ZFP292 stabilize CoREST-linked LSD1 engagement at bivalent promoters to safeguard pluripotency

RLF/ZFP292 stabilize CoREST-linked LSD1 engagement...

12

Integrated single-cell and spatial transcriptomic profiling in ALS uncovers peripheral-to-central immune infiltration and reprogramming

Integrated single-cell and spatial transcriptomic ...

18

Beneficial microbes in agriculture: curse or blessing?

Beneficial microbes in agriculture: curse or bless...

25

White matter lesions disrupt cholinergic pathways important for cognition in Parkinson’s disease

White matter lesions disrupt cholinergic pathways ...

29

Molecular and therapeutic frontiers in anemia therapy

Molecular and therapeutic frontiers in anemia therapy

43

Toward mutational epidemiology: using mutational signatures of environmental exposures to assess cancer risk

Toward mutational epidemiology: using mutational s...

26

Secreted GPNMB enhances uptake of fibrillar alpha- synuclein in a non-cell-autonomous process that can be blocked by anti-GPNMB antibodies

Secreted GPNMB enhances uptake of fibrillar alpha-...

22

Optics-free spatial genomics for mapping mammalian brain aging by IRISeq

Optics-free spatial genomics for mapping mammalian...

23

Biophysical principles of cell competition and elimination

Biophysical principles of cell competition and eli...

26

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome

Expanding the targeted protein degradation approac...

28

RNA-triggered cell killing with CRISPR– Cas12a2

RNA-triggered cell killing with CRISPR– Cas12a2

39

Noninvasive methods to monitor dynamic single-cell events

Noninvasive methods to monitor dynamic single-cell...

60

Cell-type-targeted mitochondrial transplantation rescues cell degeneration

Cell-type-targeted mitochondrial transplantation r...

90

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

106

Whole-body molecular and cellular mapping of the laboratory mouse

Whole-body molecular and cellular mapping of the l...

108

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

Electrophysiological development and functional pl...

100

Tissue morphology predicts telomere shortening in human tissues

Tissue morphology predicts telomere shortening in ...

81

Metapipeline-DNA: A comprehensive germline and somatic genomics Nextflow pipeline

Metapipeline-DNA: A comprehensive germline and som...

72

Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain

Genetically encoded fluorescent reporters to visua...

89

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

108

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

118

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Simultaneous epigenomic profiling and regulatory a...

151

Breeding of Cotton

Breeding of Cotton

54

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

143

THALASSEMIA

THALASSEMIA

203

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

222

NMDA RECEPTORS

245

Neural Development

Neural Development

202

Transcription Factors

Transcription Factors

224

Interferons

150

RABIES

133

ANEMIA

130

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

140

Migraine

124

Dementia

162

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

112121

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1466

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1320

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

4852

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

443

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

427

HEAD AND NECK CANCER

HEAD AND NECK CANCER

482

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

294

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

426

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

465

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

410

Gestational diabetes therapeutics

Gestational diabetes therapeutics

422

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

446

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

641

Different types of Alzheimer's disease

Different types of Alzheimer's disease

538

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

465

Alzheimer’s therapeutics

Alzheimer’s therapeutics

508

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

488

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

498

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

439

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

443

APOE in Alzheimer’s

APOE in Alzheimer’s

566

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

588

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

641

Different types of Alzheimer's disease

Different types of Alzheimer's disease

538

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

465

Alzheimer’s therapeutics

Alzheimer’s therapeutics

508

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

488

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

498

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

439

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

443

APOE in Alzheimer’s

APOE in Alzheimer’s

566

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

588

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

441

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

509

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

407

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

410

Gestational diabetes therapeutics

Gestational diabetes therapeutics

422

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

446