Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

14500

Evolutionary Constraints on Total Energy Expenditure

Science Hangouts

Evolutionary Constraints on Total Energy Expenditure

123

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

Science Hangouts

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

113

Science News Highlights

Targeting kinesins!

News highlights

Targeting kinesins!

3

Protecting human pancreatic beta cells from autoimmune destruction

News highlights

Protecting human pancreatic beta cells from autoimmune...

10

Obesity and Cancer

News highlights

Obesity and Cancer

13

News

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

18

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

43

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

16

How blood cells release key signaling lipid

How blood cells release key signaling lipid

29

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

18

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

56

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

35

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

47

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

32

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

34

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

41

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

36

Generational chromosome repair!

Generational chromosome repair!

30

Astrocyte cilium and stress behavior

Astrocyte cilium and stress behavior

43

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

56

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

41

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

36

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

50

Using noise to regulate information flow in neural networks

Using noise to regulate information flow in neural...

41

How can music help us recover from stress?

How can music help us recover from stress?

49

Neural mechanisms of brain multitasking

Neural mechanisms of brain multitasking

56

Where and how Alzheimer's tangles begin

Where and how Alzheimer's tangles begin

70

Atlas of the brain’s striatum

Atlas of the brain’s striatum

65

Psilocybin prevents chemotherapy-induced peripheral neuropathy

Psilocybin prevents chemotherapy-induced periphera...

69

Difference in the gut derived EVs in Parkinson’s disease

Difference in the gut derived EVs in Parkinson’s d...

59

Aberrant receptor tyrosine kinase 4 expression drives Alzheimer’s pathology

Aberrant receptor tyrosine kinase 4 expression dri...

99

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

38

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

67

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

73

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

88

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

81

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

79

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

86

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

99

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

90

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

89

Protecting cells from iron overload

Protecting cells from iron overload

103

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

105

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

94

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

32

Mechanism of obesity relapse

Mechanism of obesity relapse

89

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

81

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

90

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

476

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

157

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

181

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

204

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

248

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

238

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

218

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

249

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

249

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

47

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

34

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

176

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

135

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

54

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

47

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

70

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

143

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

101

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

114

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

104

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

123

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

118

Protein-based data storage

Protein-based data storage

192

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

185

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

197

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

344

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

255

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

306

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

361

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

351

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

315

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

360

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

318

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

388

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

383

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

35

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

83

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

60

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

97

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

79

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

89

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

90

A novel 3D brain tissue model

A novel 3D brain tissue model

127

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

94

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

100

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

176

Reverting aged cells to stem cells

Reverting aged cells to stem cells

241

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

130

Generational chromosome repair!

Generational chromosome repair!

30

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

29

Is our personality written in our genes?

Is our personality written in our genes?

140

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

58

How chromosomes find their partners

How chromosomes find their partners

123

New gene activation tool!

New gene activation tool!

89

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

92

First complete marmoset genome

First complete marmoset genome

100

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

137

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

134

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

141

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

160

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

179

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

53

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

118

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

150

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

152

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

139

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

143

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

237

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

267

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

262

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

281

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

596

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

582

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

577

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

18

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

32

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

45

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

76

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

77

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

105

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

94

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

104

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

125

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

125

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

166

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

146

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

135

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

49

Postbiotics may boost female fertility

Postbiotics may boost female fertility

103

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

123

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

122

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

174

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

192

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

230

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

213

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

269

sncRNAs in sperm aging

sncRNAs in sperm aging

334

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

270

How reproductive organs form

How reproductive organs form

369

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

275

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

18

How blood cells release key signaling lipid

How blood cells release key signaling lipid

29

Transcription of eight letter codon!

Transcription of eight letter codon!

56

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

61

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

51

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

58

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

71

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

77

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

77

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

88

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

98

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

61

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

67

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

16

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

51

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

79

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

77

Methylation puts parasites in motion

Methylation puts parasites in motion

65

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

165

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

201

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

116

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

110

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

124

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

114

Fasting primes gut microbiome to improve intestinal recovery after radiation treatment

Fasting primes gut microbiome to improve intestina...

121

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

135

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

44

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

49

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

61

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

66

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

72

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

102

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

147

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

157

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

143

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

142

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

167

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

145

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

153

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

70

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

77

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

158

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

134

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

139

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

131

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

133

Cure for dry eye disease

Cure for dry eye disease

159

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

169

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

191

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

170

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

168

Nicotine Biosynthesis!

Nicotine Biosynthesis!

303

Why some people can fight infections better than others?

Why some people can fight infections better than o...

97

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

72

Gene circuits of human immunity

Gene circuits of human immunity

89

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

82

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

96

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

71

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

92

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

84

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

89

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

97

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

90

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

122

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

88

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

72

Air-permeable hydrogels!

Air-permeable hydrogels!

135

Temperature behaves differently in the cell

Temperature behaves differently in the cell

132

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

123

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

165

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

189

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

262

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

542

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

435

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

922

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

533

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

504

Printed skin to replace animal testing

Printed skin to replace animal testing

505

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

77

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

85

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

62

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

78

Viral RNA elements functional map!

Viral RNA elements functional map!

76

How proteins change shape and move

How proteins change shape and move

84

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

79

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

137

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

83

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

93

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

131

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

531

Molecular map of liver disease

Molecular map of liver disease

123

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

140

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

288

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

483

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

495

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

467

How the brain regulates emotions

How the brain regulates emotions

698

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

546

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

546

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

571

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

538

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

537

Link between dietary choices and brain health

Link between dietary choices and brain health

508

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

494

Research

Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies

Kinesins as dynamic drug targets: structural insig...

8

Engineering the insulin signal peptide to protect human pancreatic beta cells from autoimmune destruction

Engineering the insulin signal peptide to protect ...

20

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Amygdala astrocyte primary cilium mechanisms contr...

23

Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B

Structure and mechanism of human sphingosine-1-pho...

826

Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis

Artery tertiary lymphoid organs encode a pathogeni...

30

Contrastive learning unites sequence and structure in a global representation of protein space

Contrastive learning unites sequence and structure...

861

Obesity and Cancer

Obesity and Cancer

35

Rethinking the origins and functions of adaptive immunity

Rethinking the origins and functions of adaptive i...

51

A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen

A cryptic symmetry switch allosterically controls ...

38

Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes

Paediatric proteomic signatures of cardiometabolic...

29

Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease

Fibronectin mediates APOE4-driven blood–brain barr...

493

Micronutrients, the gut microbiota, and infection susceptibility in infants

Micronutrients, the gut microbiota, and infection ...

45

Genomic newborn screening, a healthcare system transformation

Genomic newborn screening, a healthcare system tra...

27

Kinesins as dynamic drug targets: structural insights and emerging therapeutic strategies

Kinesins as dynamic drug targets: structural insig...

8

Engineering the insulin signal peptide to protect human pancreatic beta cells from autoimmune destruction

Engineering the insulin signal peptide to protect ...

20

Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours

Amygdala astrocyte primary cilium mechanisms contr...

23

Structure and mechanism of human sphingosine-1-phosphate transporter MFSD2B

Structure and mechanism of human sphingosine-1-pho...

826

Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis

Artery tertiary lymphoid organs encode a pathogeni...

30

Contrastive learning unites sequence and structure in a global representation of protein space

Contrastive learning unites sequence and structure...

861

Obesity and Cancer

Obesity and Cancer

35

Rethinking the origins and functions of adaptive immunity

Rethinking the origins and functions of adaptive i...

51

A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen

A cryptic symmetry switch allosterically controls ...

38

Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes

Paediatric proteomic signatures of cardiometabolic...

29

Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease

Fibronectin mediates APOE4-driven blood–brain barr...

493

Micronutrients, the gut microbiota, and infection susceptibility in infants

Micronutrients, the gut microbiota, and infection ...

45

Genomic newborn screening, a healthcare system transformation

Genomic newborn screening, a healthcare system tra...

27

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

110

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

226

Automated prototyping of genetic codes

Automated prototyping of genetic codes

234

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

264

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

205

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

92

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

74

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

3008

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

64

Drug screen and machine learning predict neuroprotective agents in a preclinical human model of childhood dementia

Drug screen and machine learning predict neuroprot...

71

Human brain organoids record the passage of time over multiple years

Human brain organoids record the passage of time o...

71

Temporal uncoupling of radial glia lineage progression in cortical organoids

Temporal uncoupling of radial glia lineage progres...

2659

Trans-regulatory gene mapping prioritizes disease drivers in asthma

Trans-regulatory gene mapping prioritizes disease ...

74

Breeding of Cotton

Breeding of Cotton

616

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

775

THALASSEMIA

THALASSEMIA

932

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

917

NMDA RECEPTORS

462

Neural Development

Neural Development

450

Transcription Factors

Transcription Factors

438

Interferons

390

RABIES

399

ANEMIA

387

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

391

Migraine

315

Dementia

410

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

53

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

66

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

640

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

270

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

3139

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

227

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

61

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIENCE IN RTT SYNDROME

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIE...

3133

Oxidative Signaling in Plants

Oxidative Signaling in Plants

125

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

156

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

159926

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1988

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1638

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

523

Gestational diabetes therapeutics

Gestational diabetes therapeutics

619

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

570

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

912

Different types of Alzheimer's disease

Different types of Alzheimer's disease

663

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

599

Alzheimer’s therapeutics

Alzheimer’s therapeutics

725

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

610

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

616

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

561

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

553

APOE in Alzheimer’s

APOE in Alzheimer’s

780

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

707

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

912

Different types of Alzheimer's disease

Different types of Alzheimer's disease

663

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

599

Alzheimer’s therapeutics

Alzheimer’s therapeutics

725

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

610

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

616

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

561

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

553

APOE in Alzheimer’s

APOE in Alzheimer’s

780

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

707

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

561

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

716

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

495

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

523

Gestational diabetes therapeutics

Gestational diabetes therapeutics

619

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

570