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All Publications Protocols Presentations Posters
Glutamine metabolic interaction network reshapes tumor immunotherapy resistance

Glutamine metabolic interaction network resha...

 20

Arabidopsis uses distinct coumarins and bacterial pathways for pH-adaptive iron acquisition

Arabidopsis uses distinct coumarins and bacte...

 18

A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis

A DNA Typewriter records the cell lineage his...

 14

Acute viral infection accelerates neurodegeneration in a mouse model of ALS

Acute viral infection accelerates neurodegene...

 15

Glutamine metabolic interaction network reshapes tumor immunotherapy resistance

Glutamine metabolic interaction network resha...

 20

Arabidopsis uses distinct coumarins and bacterial pathways for pH-adaptive iron acquisition

Arabidopsis uses distinct coumarins and bacte...

 18

A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis

A DNA Typewriter records the cell lineage his...

 14

Acute viral infection accelerates neurodegeneration in a mouse model of ALS

Acute viral infection accelerates neurodegene...

 15

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardize...

 26

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and cla...

 65

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innova...

 56

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 92

Breeding of Cotton

Breeding of Cotton

 743

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 982

THALASSEMIA

THALASSEMIA

 1083

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1084

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurol...

 43

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for canc...

 54

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-F...

 71

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrang...

 7605

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Science Hangouts

Dimerization and activation of receptor tyrosine kinases:  insights from quantitative fluorescence studies
Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

 16255

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty
Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

 82

Systems Biology & Medicine: Markers, Mechanisms and Pathways
Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

 105

Science News Highlights

Tumor immunotherapy resistance reshaped by glutamine metabolic interaction network
News highlights

Tumor immunotherapy resistance reshaped by glutamine metabolic interaction network

 10

Controlling compulsive eating
News highlights

Controlling compulsive eating

 13

An AI curated single-cell data RNA-seq repository
News highlights

An AI curated single-cell data RNA-seq repository

 14

News

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The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

 92

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

 15

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

 27

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

 24

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

 22

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

 20

Regulating cellular recycling

Regulating cellular recycling

 30

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

 44

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

 52

Controlling aging muscle

Controlling aging muscle

 412

How plants sense touch?

How plants sense touch?

 97

Microplastics cause fatty liver disease 

Microplastics cause fatty liver disease 

 56

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

 3216

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

 24

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

 20

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

 46

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

 98

Neck lymph node removal linked to increased risk of cognitive decline

Neck lymph node removal linked to increased risk o...

 175

How the biological clock regulates phases of wakefulness

How the biological clock regulates phases of wakef...

 85

Prion-like transmission of tau in the mouse brain

Prion-like transmission of tau in the mouse brain

 65

What happens in the brain when cannabis makes you anxious?

What happens in the brain when cannabis makes you ...

 85

Blocking immune cells’ path into brain limits neurodegeneration

Blocking immune cells’ path into brain limits neur...

 195

Brain circuit that remembers stresses identified!

Brain circuit that remembers stresses identified!

 159

Alzheimer’s disease and aging reshape brain communication in different ways

Alzheimer’s disease and aging reshape brain commun...

 199

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

 78

Changes in retinal dopamine balance during inherited retinal degenerations

Changes in retinal dopamine balance during inherit...

 49

Regulating cellular recycling

Regulating cellular recycling

 30

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

 59

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

 100

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

 665

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

 102

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

 107

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

 209

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

 125

Cancer-linked protein binds to chromosome in unexpected way 

Cancer-linked protein binds to chromosome in unexp...

 86

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

 70

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

 95

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

 104

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

 84

Microplastics cause fatty liver disease 

Microplastics cause fatty liver disease 

 56

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

 419

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

 334

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

 98

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

 85

Mechanism of obesity relapse

Mechanism of obesity relapse

 195

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

 153

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

 135

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

 540

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

 198

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

 231

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

 280

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

 301

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

 52

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

 435

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

 158

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

 150

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

 237

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

 282

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

 83

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

 82

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

 121

AI language models for aging biology

AI language models for aging biology

 212

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

 112

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

 147

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

 179

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

 47

Protein-based data storage

Protein-based data storage

 239

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

 228

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

 242

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

 385

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

 304

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

 347

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 410

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 408

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 363

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 399

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 360

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 439

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

 59

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

 150

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

 130

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

 127

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

 100

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

 137

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

 115

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

 144

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

 137

A novel 3D brain tissue model

A novel 3D brain tissue model

 166

EV  secretome to treat cardiac fibrosis

EV  secretome to treat cardiac fibrosis

 161

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

 148

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

 222

Heredity is about more than just DNA

Heredity is about more than just DNA

 57

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

 65

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

 131

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

 93

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

 89

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

 79

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

 89

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

 81

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

 94

Generational chromosome repair!

Generational chromosome repair!

 89

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

 85

Is our personality written in our genes?

Is our personality written in our genes?

 187

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

 113

Controlling aging muscle

Controlling aging muscle

 412

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

 130

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

 84

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

 84

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

 117

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

 153

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

 190

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

 196

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

 181

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

 185

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

 284

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

 309

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

 305

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

 59

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

 86

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

 84

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

 70

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

 90

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

 129

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

 115

Capillaries and not arteries give rise to  backup blood vessels

Capillaries and not arteries give rise to backup ...

 112

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

 147

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

 135

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

 143

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

 162

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

 163

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

 208

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

 176

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

 82

Postbiotics may boost female fertility

Postbiotics may boost female fertility

 153

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

 158

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

 166

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

 245

Aging human breast atlas reveals  cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

 235

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

 270

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

 254

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

 318

sncRNAs in sperm aging

sncRNAs in sperm aging

 376

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

 301

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

 44

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

 3216

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

 168

New role for cohesin in DNA replication

New role for cohesin in DNA replication

 137

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

 74

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

 116

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

 59

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

 76

How a protein shapes the cell membrane

How a protein shapes the cell membrane

 83

 Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

 Structural basis of metabotropic glutamate recept...

 94

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

 68

How blood cells release key signaling lipid

How blood cells release key signaling lipid

 85

Transcription of eight letter codon!

Transcription of eight letter codon!

 93

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

 92

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

 22

Alternate pathway of antibiotic resistance 

Alternate pathway of antibiotic resistance 

 53

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

 40

How bacteria fight viruses

How bacteria fight viruses

 59

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

 1115

 How Epstein-Barr Virus triggers multiple sclerosis relapse

 How Epstein-Barr Virus triggers multiple sclerosi...

 175

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

 75

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

 75

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

 122

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

 64

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

 78

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

 134

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

 27

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

 146

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

 74

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

 84

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

 88

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

 90

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

 93

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

 127

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

 183

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

 186

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

 174

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

 171

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

 195

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

 15

How plants sense touch?

How plants sense touch?

 97

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

 74

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

 65

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

 111

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

 102

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

 110

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

 182

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

 162

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

 177

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

 162

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

 165

Cure for dry eye disease

Cure for dry eye disease

 199

Sex difference in immune ageing

Sex difference in immune ageing

 76

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

 92

Why some people can fight infections better than others?

Why some people can fight infections better than o...

 120

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

 112

Gene circuits of human immunity

Gene circuits of human immunity

 131

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

 113

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

 131

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

 96

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 117

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

 116

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

 108

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

 123

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

 115

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

 74

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

 134

Air-permeable hydrogels!

Air-permeable hydrogels!

 167

Temperature behaves differently in the cell

Temperature behaves differently in the cell

 164

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

 146

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

 192

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

 221

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

 303

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 570

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 466

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 954

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 563

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 563

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

 463

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

 48

A world-first DNA computer 

A world-first DNA computer 

 50

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

 95

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

 68

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

 101

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

 73

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

 104

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

 109

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

 86

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

 105

Viral RNA elements functional map!

Viral RNA elements functional map!

 100

How proteins change shape and move

How proteins change shape and move

 105

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

 180

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 324

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 507

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 533

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 495

How the brain regulates emotions

How the brain regulates emotions

 721

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 585

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 595

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 591

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 565

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 560

Link between dietary choices and brain health

Link between dietary choices and brain health

 527

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 523

Research

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    • Publications
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    • Posters
Glutamine metabolic interaction network reshapes tumor immunotherapy resistance

Glutamine metabolic interaction network reshapes t...

 20

Arabidopsis uses distinct coumarins and bacterial pathways for pH-adaptive iron acquisition

Arabidopsis uses distinct coumarins and bacterial ...

 18

A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis

A DNA Typewriter records the cell lineage history ...

 14

Acute viral infection accelerates neurodegeneration in a mouse model of ALS

Acute viral infection accelerates neurodegeneratio...

 15

Mechanism of membrane perforation in rotavirus cell entry

Mechanism of membrane perforation in rotavirus cel...

 11

Purinergic receptor activation rectifies autism-associated endothelial dysfunction

Purinergic receptor activation rectifies autism-as...

 25

Anterior zona incerta to ventral tegmental area  circuit controls compulsive eating in a binge-eating- disorder mouse model

Anterior zona incerta to ventral tegmental area c...

 20

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

 26

Deep-learning single-cell profiling uncovers interbacterial and drug-driven reshaping of pathogen virulence

Deep-learning single-cell profiling uncovers inter...

 17

Mitochondrial membrane lipid cardiolipin controls fiber-type adaptations in aging muscle via estrogen-related receptor γ

Mitochondrial membrane lipid cardiolipin controls ...

 27

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

 1305

Patient-derived organoids in hematologic malignancies: Fidelity and translation beyond animals

Patient-derived organoids in hematologic malignanc...

 33

A sequential MAP kinase cascade regulates mechanical signalling

A sequential MAP kinase cascade regulates mechanic...

 54

Glutamine metabolic interaction network reshapes tumor immunotherapy resistance

Glutamine metabolic interaction network reshapes t...

 20

Arabidopsis uses distinct coumarins and bacterial pathways for pH-adaptive iron acquisition

Arabidopsis uses distinct coumarins and bacterial ...

 18

A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis

A DNA Typewriter records the cell lineage history ...

 14

Acute viral infection accelerates neurodegeneration in a mouse model of ALS

Acute viral infection accelerates neurodegeneratio...

 15

Mechanism of membrane perforation in rotavirus cell entry

Mechanism of membrane perforation in rotavirus cel...

 11

Purinergic receptor activation rectifies autism-associated endothelial dysfunction

Purinergic receptor activation rectifies autism-as...

 25

Anterior zona incerta to ventral tegmental area  circuit controls compulsive eating in a binge-eating- disorder mouse model

Anterior zona incerta to ventral tegmental area c...

 20

Deep-learning single-cell profiling uncovers interbacterial and drug-driven reshaping of pathogen virulence

Deep-learning single-cell profiling uncovers inter...

 17

Mitochondrial membrane lipid cardiolipin controls fiber-type adaptations in aging muscle via estrogen-related receptor γ

Mitochondrial membrane lipid cardiolipin controls ...

 27

The structural basis for LRRK2’s activation and autoinhibition

The structural basis for LRRK2’s activation and au...

 1305

Patient-derived organoids in hematologic malignancies: Fidelity and translation beyond animals

Patient-derived organoids in hematologic malignanc...

 33

A sequential MAP kinase cascade regulates mechanical signalling

A sequential MAP kinase cascade regulates mechanic...

 54

Size-dependent plastic exposure disrupts macrophage function and tissue-specific metabolism

Size-dependent plastic exposure disrupts macrophag...

 29

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

 26

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

 65

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

 56

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 92

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

 93

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

 111

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

 195

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

 101

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

 85

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

 72

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

 67

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

 68

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

 66

Breeding of Cotton

Breeding of Cotton

 743

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 982

THALASSEMIA

THALASSEMIA

 1083

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1084

NMDA RECEPTORS

NMDA RECEPTORS

 489

Neural Development

Neural Development

 476

Transcription Factors

Transcription Factors

 466

Interferons

Interferons

 416

RABIES

RABIES

 427

ANEMIA

ANEMIA

 440

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

 415

Migraine

Migraine

 347

Dementia

Dementia

 437

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

 43

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

 54

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

 71

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

 7605

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

 58

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

 77

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

 2959

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

 118

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

 115

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

 91

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

 2383

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

 56

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

 109

School Science

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Disease Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 548

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 643

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 593

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 940

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 694

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 627

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 781

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 669

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 672

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 610

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 606

APOE in Alzheimer’s

APOE in Alzheimer’s

 838

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 762

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 940

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 694

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 627

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 781

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 669

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 672

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 610

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 606

APOE in Alzheimer’s

APOE in Alzheimer’s

 838

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 762

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 581

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 774

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 557

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 548

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 643

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 593

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