Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

14398

Evolutionary Constraints on Total Energy Expenditure

Science Hangouts

Evolutionary Constraints on Total Energy Expenditure

117

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

Science Hangouts

Discovery of a Seminal Fluid Microbiome and How it Might Influence Health of the Male and His Offspring

105

Science News Highlights

Obesity and Cancer

News highlights

Obesity and Cancer

8

Expanding role of adaptive immunity

News highlights

Expanding role of adaptive immunity

12

Role of micronutrients in shaping infant gut microbiota, and infection susceptibility

News highlights

Role of micronutrients in shaping infant gut microbiot...

14

News

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

7

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

9

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

8

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

26

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

22

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

33

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

29

Generational chromosome repair!

Generational chromosome repair!

25

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

26

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

40

Mechanism of obesity relapse

Mechanism of obesity relapse

69

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

30

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

65

Inhibitory brain circuits suppress glioblastoma growth

Inhibitory brain circuits suppress glioblastoma gr...

7

Linking deep-sleep loss to Alzheimer’s-related protein buildup

Linking deep-sleep loss to Alzheimer’s-related pro...

33

How APOE4 variant causes brain damage in Alzheimer’s disease

How APOE4 variant causes brain damage in Alzheime...

29

Cortical neurons involved in sleep identified!

Cortical neurons involved in sleep identified!

40

Using noise to regulate information flow in neural networks

Using noise to regulate information flow in neural...

32

How can music help us recover from stress?

How can music help us recover from stress?

38

Neural mechanisms of brain multitasking

Neural mechanisms of brain multitasking

49

Where and how Alzheimer's tangles begin

Where and how Alzheimer's tangles begin

66

Atlas of the brain’s striatum

Atlas of the brain’s striatum

57

Psilocybin prevents chemotherapy-induced peripheral neuropathy

Psilocybin prevents chemotherapy-induced periphera...

68

Difference in the gut derived EVs in Parkinson’s disease

Difference in the gut derived EVs in Parkinson’s d...

56

Aberrant receptor tyrosine kinase 4 expression drives Alzheimer’s pathology

Aberrant receptor tyrosine kinase 4 expression dri...

96

Cognitive decline in human aging from oligodendrocyte dysfunction

Cognitive decline in human aging from oligodendroc...

65

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

34

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

64

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

69

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

83

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

77

Metastatic triple-negative breast cancer regulated by miRNA

Metastatic triple-negative breast cancer regulated...

76

‘Molecular glue’ turns a cancer driver into a built-in kill switch

‘Molecular glue’ turns a cancer driver into a buil...

83

Gastrointestinal cancer detection using mouth to gut microbe signatures

Gastrointestinal cancer detection using mouth to g...

94

Amino acid metabolism rewiring leads to hormone therapy resistance in prostate cancer

Amino acid metabolism rewiring leads to hormone th...

86

Blood metabolomic signatures linking air pollution to lung cancer

Blood metabolomic signatures linking air pollution...

86

Protecting cells from iron overload

Protecting cells from iron overload

100

Cancer cells hijack a fatty acid to escape immune attack in liver metastases

Cancer cells hijack a fatty acid to escape immune ...

104

Immunosuppression switch in cancer identified!

Immunosuppression switch in cancer identified!

91

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

26

Mechanism of obesity relapse

Mechanism of obesity relapse

69

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

65

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

87

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

473

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

153

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

177

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

200

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

244

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

234

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

214

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

247

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

247

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

8

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

22

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

165

Mammalian genes can combine to make previously unknown mRNAs, proteins

Mammalian genes can combine to make previously unk...

129

Taste connectome of adult Drosophila

Taste connectome of adult Drosophila

50

Proteomics and AI identify plasma biomarkers for vasculitis

Proteomics and AI identify plasma biomarkers for v...

41

Defining the degradability capability of protein degraders

Defining the degradability capability of protein d...

65

Tissue-specific aging signatures using histology and AI

Tissue-specific aging signatures using histology a...

140

AI based imaging to see tumor boundaries in 3D within 30 minutes

AI based imaging to see tumor boundaries in 3D wit...

96

AI designed small molecule inhibitor against pancreatic cancer

AI designed small molecule inhibitor against pancr...

110

Fundamental insights on movement planning in the brain

Fundamental insights on movement planning in the b...

100

AI to generate and analyze personality questionnaires

AI to generate and analyze personality questionnaires

120

AI designs functional bacteriophages from scratch

AI designs functional bacteriophages from scratch

114

Protein-based data storage

Protein-based data storage

186

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

183

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

193

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

341

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

252

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

302

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

355

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

348

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

313

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

357

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

315

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

385

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

382

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

9

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

68

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

56

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

92

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

75

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

86

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

85

A novel 3D brain tissue model

A novel 3D brain tissue model

124

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

91

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

94

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

172

Reverting aged cells to stem cells

Reverting aged cells to stem cells

237

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

126

Generational chromosome repair!

Generational chromosome repair!

25

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

27

Is our personality written in our genes?

Is our personality written in our genes?

136

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

55

How chromosomes find their partners

How chromosomes find their partners

120

New gene activation tool!

New gene activation tool!

85

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

90

First complete marmoset genome

First complete marmoset genome

97

Mechanisms of α-ketoglutarate signaling to chromatin

Mechanisms of α-ketoglutarate signaling to chromatin

132

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

129

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

138

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

156

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

175

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

41

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

115

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

147

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

149

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

135

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

141

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

233

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

264

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

260

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

276

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

593

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

580

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

573

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

26

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

39

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

72

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

73

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

103

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

91

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

101

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

123

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

122

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

163

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

142

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

130

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

152

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

43

Postbiotics may boost female fertility

Postbiotics may boost female fertility

99

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

120

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

119

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

168

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

190

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

228

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

211

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

266

sncRNAs in sperm aging

sncRNAs in sperm aging

330

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

267

How reproductive organs form

How reproductive organs form

366

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

273

Transcription of eight letter codon!

Transcription of eight letter codon!

55

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

54

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

51

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

57

New method to synthesize proteins by modifying tRNAs

New method to synthesize proteins by modifying tRNAs

65

Key cancer-related receptor is regulated by glycan interactions on cell surfaces

Key cancer-related receptor is regulated by glycan...

73

Modified tRNA rescues nonsense mutations in cystic fibrosis

Modified tRNA rescues nonsense mutations in cystic...

76

Altered mitochondrial metabolism in senescent cells promote inflammation in aged cells

Altered mitochondrial metabolism in senescent cell...

87

Native RNA Polymerase II Transcription Complexes structure revealed!

Native RNA Polymerase II Transcription Complexes s...

94

Membrane protein quality control at the ribosome

Membrane protein quality control at the ribosome

58

How the liver’s internal clock influence metabolism

How the liver’s internal clock influence metabolism

62

Hidden function of a protein to influence leukemia drug

Hidden function of a protein to influence leukemia...

61

How antibiotics work inhibiting RNA polymerase?

How antibiotics work inhibiting RNA polymerase?

78

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

47

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

78

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

72

Methylation puts parasites in motion

Methylation puts parasites in motion

62

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

163

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

197

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

114

Understanding sepsis infections using cellular behavioromics

Understanding sepsis infections using cellular beh...

107

Antibiotic resistant gene found in Australian soil

Antibiotic resistant gene found in Australian soil

120

Functional biomarker for RSV severity identified!

Functional biomarker for RSV severity identified!

111

Fasting primes gut microbiome to improve intestinal recovery after radiation treatment

Fasting primes gut microbiome to improve intestina...

118

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

132

Structural insight into the mechanism of bacterial pili retraction

Structural insight into the mechanism of bacterial...

136

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

30

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

43

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

59

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

65

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

69

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

97

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

145

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

155

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

142

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

138

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

163

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

140

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

150

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

67

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

75

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

155

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

127

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

134

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

129

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

131

Cure for dry eye disease

Cure for dry eye disease

154

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

166

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

190

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

167

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

166

Nicotine Biosynthesis!

Nicotine Biosynthesis!

300

Why some people can fight infections better than others?

Why some people can fight infections better than o...

94

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

70

Gene circuits of human immunity

Gene circuits of human immunity

86

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

80

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

92

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

69

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

89

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

82

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

86

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

95

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

87

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

120

Leveraging COVID-19 immune memory into a weapon against cancer

Leveraging COVID-19 immune memory into a weapon ag...

86

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

68

Air-permeable hydrogels!

Air-permeable hydrogels!

131

Temperature behaves differently in the cell

Temperature behaves differently in the cell

131

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

122

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

161

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

187

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

259

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

541

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

434

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

918

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

531

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

500

Printed skin to replace animal testing

Printed skin to replace animal testing

504

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

73

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

85

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

59

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

75

Viral RNA elements functional map!

Viral RNA elements functional map!

74

How proteins change shape and move

How proteins change shape and move

80

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

77

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

134

Mapping the 3D genome in rare immune cells

Mapping the 3D genome in rare immune cells

81

Glioblastoma isoform diversity mapping

Glioblastoma isoform diversity mapping

91

Metabolically activated molecular glue degrader platform

Metabolically activated molecular glue degrader pl...

129

New wearable ring tracks glucose, ketone and other biomarkers in sweat

New wearable ring tracks glucose, ketone and other...

529

Molecular map of liver disease

Molecular map of liver disease

118

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

134

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

285

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

481

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

493

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

465

How the brain regulates emotions

How the brain regulates emotions

695

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

543

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

543

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

570

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

536

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

536

Link between dietary choices and brain health

Link between dietary choices and brain health

507

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

491

Research

Contrastive learning unites sequence and structure in a global representation of protein space

Contrastive learning unites sequence and structure...

124

Obesity and Cancer

Obesity and Cancer

19

Rethinking the origins and functions of adaptive immunity

Rethinking the origins and functions of adaptive i...

27

A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen

A cryptic symmetry switch allosterically controls ...

26

Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes

Paediatric proteomic signatures of cardiometabolic...

22

Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease

Fibronectin mediates APOE4-driven blood–brain barr...

487

Micronutrients, the gut microbiota, and infection susceptibility in infants

Micronutrients, the gut microbiota, and infection ...

37

Genomic newborn screening, a healthcare system transformation

Genomic newborn screening, a healthcare system tra...

22

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

26

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

29

Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga

Transgenerational chromosome repair in the asexual...

432

Neocortical long-range inhibition promotes cortical synchrony and sleep

Neocortical long-range inhibition promotes cortica...

39

Adipose TGFβ-asprosin memory promotes obesity relapse and offspring obesity susceptibility

Adipose TGFβ-asprosin memory promotes obesity rela...

384

Contrastive learning unites sequence and structure in a global representation of protein space

Contrastive learning unites sequence and structure...

124

Obesity and Cancer

Obesity and Cancer

19

Rethinking the origins and functions of adaptive immunity

Rethinking the origins and functions of adaptive i...

27

A cryptic symmetry switch allosterically controls how the PF4 self-protein turns into a pathogenic antigen

A cryptic symmetry switch allosterically controls ...

26

Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes

Paediatric proteomic signatures of cardiometabolic...

22

Fibronectin mediates APOE4-driven blood–brain barrier dysfunction in Alzheimer’s disease

Fibronectin mediates APOE4-driven blood–brain barr...

487

Micronutrients, the gut microbiota, and infection susceptibility in infants

Micronutrients, the gut microbiota, and infection ...

37

Genomic newborn screening, a healthcare system transformation

Genomic newborn screening, a healthcare system tra...

22

Transgenerational chromosome repair in the asexual bdelloid rotifer Adineta vaga

Transgenerational chromosome repair in the asexual...

432

Neocortical long-range inhibition promotes cortical synchrony and sleep

Neocortical long-range inhibition promotes cortica...

39

Adipose TGFβ-asprosin memory promotes obesity relapse and offspring obesity susceptibility

Adipose TGFβ-asprosin memory promotes obesity rela...

384

Gasdermin D-mediated delivery of caspase inhibitors to suppress pyroptosis

Gasdermin D-mediated delivery of caspase inhibitor...

26

B cells enter the synaptic conversation

B cells enter the synaptic conversation

43

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

85

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

196

Automated prototyping of genetic codes

Automated prototyping of genetic codes

205

Lysosome-targeted protein degradation platforms for spatiotemporally controlled degradation

Lysosome-targeted protein degradation platforms fo...

236

Combined multi-omics and multi-spectral profiling of plasma extracellular vesicles reveals liquid biopsy biomarkers for glioma diagnosis

Combined multi-omics and multi-spectral profiling ...

203

Ultrafast and reference-free sequence discovery in single-cell data

Ultrafast and reference-free sequence discovery in...

90

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

Genome-scale perturb-seq in primary human CD4+ T c...

71

TIGRa: An ultra-compact programmable activator enabling multiplexed and efficient gene regulation

TIGRa: An ultra-compact programmable activator ena...

3004

Modular plug-and-play crosslinking platform for precision-engineered hydrogels

Modular plug-and-play crosslinking platform for pr...

61

Drug screen and machine learning predict neuroprotective agents in a preclinical human model of childhood dementia

Drug screen and machine learning predict neuroprot...

67

Human brain organoids record the passage of time over multiple years

Human brain organoids record the passage of time o...

68

Temporal uncoupling of radial glia lineage progression in cortical organoids

Temporal uncoupling of radial glia lineage progres...

2657

Trans-regulatory gene mapping prioritizes disease drivers in asthma

Trans-regulatory gene mapping prioritizes disease ...

70

Breeding of Cotton

Breeding of Cotton

579

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

751

THALASSEMIA

THALASSEMIA

909

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

881

NMDA RECEPTORS

461

Neural Development

Neural Development

448

Transcription Factors

Transcription Factors

432

Interferons

385

RABIES

395

ANEMIA

384

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

389

Migraine

314

Dementia

408

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

26

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY RITONAVIRIN TRIPLE NEGATIVE BREAST CANCER CELLS

EVIDENCES OF INTERLEUKIN 20 RECEPTOR A BLOCKADE BY...

29

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABOLIC COUPLING THAT REGULATES CIRCADIAN CLOCK

REDOX PROTEOMICS REVEALS A RECIPROCAL REDOX-METABO...

617

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUINONE- MEDIATED DNA DAMAGE, APOPTOSIS SIGNALING, AND TUMOR SUPPRESSION IN COLORECTALCANCER

COPPER-DRIVEN REDOX MODULATION AMPLIFIES THYMOQUIN...

240

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOVER BY POTENT SMALL MOLECULE INHIBITOR OF USP14

PROTECTIVE EFFECT OF ENHANCED MITOCHONDRIAL TURNOV...

3138

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTERACTION FRAMEWORK IN CHLAMYDOMONAS REINHARDTII

FINDING TROUBLE IN PAIRS: A SYNTHETIC GENETIC INTE...

221

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENTIAL THERAPEUTIC TARGET IN ENDOMETRIAL CANCER

NUCLEOCYTOPLASMIC TRANSPORT INHIBITION AS A POTENT...

57

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIENCE IN RTT SYNDROME

DYSREGULATED AKT–FOXO3A AXIS IMPAIRS REDOX RESILIE...

3131

Oxidative Signaling in Plants

Oxidative Signaling in Plants

120

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

ATAF1 IS A NOVEL SUBSTRATE OF SnRK2 KINASES

154

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

159923

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1982

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1634

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

521

Gestational diabetes therapeutics

Gestational diabetes therapeutics

617

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

568

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

910

Different types of Alzheimer's disease

Different types of Alzheimer's disease

660

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

596

Alzheimer’s therapeutics

Alzheimer’s therapeutics

723

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

608

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

613

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

554

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

550

APOE in Alzheimer’s

APOE in Alzheimer’s

776

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

704

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

910

Different types of Alzheimer's disease

Different types of Alzheimer's disease

660

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

596

Alzheimer’s therapeutics

Alzheimer’s therapeutics

723

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

608

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

613

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

554

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

550

APOE in Alzheimer’s

APOE in Alzheimer’s

776

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

704

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

558

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

715

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

493

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

521

Gestational diabetes therapeutics

Gestational diabetes therapeutics

617

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

568