Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

16505

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

101

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

122

Science News Highlights

Quantifying metabolism in patients with cancer

News highlights

Quantifying metabolism in patients with cancer

0

Functional specificity of E2F3 isoforms

News highlights

Functional specificity of E2F3 isoforms

16

Where mucosal innate immune memory encoded?

News highlights

Where mucosal innate immune memory encoded?

18

News

How critical brain cells misfire in Alzheimer's

How critical brain cells misfire in Alzheimer's

568

How plants read fungal warning signs

How plants read fungal warning signs

50

AI tool for designing biomolecules with atomic precision

AI tool for designing biomolecules with atomic pre...

558

Signal timing determines cell type balance in the gut

Signal timing determines cell type balance in the gut

187

Exposure to common chemicals alter normal breast development

Exposure to common chemicals alter normal breast d...

38

Genetic differences between humans and chimpanzees

Genetic differences between humans and chimpanzees

122

AI tool identifies new dimension of biological variability in the genome

AI tool identifies new dimension of biological var...

37

Capsaicin receptor, TRPV1, responds differently to varying triggers

Capsaicin receptor, TRPV1, responds differently to...

116

Antifungal treatments during pregnancy linked to changes in foetal hormone production

Antifungal treatments during pregnancy linked to c...

27

Less invasive approach to diagnosing mitochondrial disease

Less invasive approach to diagnosing mitochondrial...

48

How a protein complex guards the entrance to channels in mitochondrial membrane cristae

How a protein complex guards the entrance to chann...

46

Reducing pathological pain!

Reducing pathological pain!

55

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

171

How critical brain cells misfire in Alzheimer's

How critical brain cells misfire in Alzheimer's

568

Capsaicin receptor, TRPV1, responds differently to varying triggers

Capsaicin receptor, TRPV1, responds differently to...

116

Reducing pathological pain!

Reducing pathological pain!

55

Effect of processed food on brain metabolism and function

Effect of processed food on brain metabolism and f...

66

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

80

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

72

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

68

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

127

Neck lymph node removal linked to increased risk of cognitive decline

Neck lymph node removal linked to increased risk o...

226

How the biological clock regulates phases of wakefulness

How the biological clock regulates phases of wakef...

104

Prion-like transmission of tau in the mouse brain

Prion-like transmission of tau in the mouse brain

89

What happens in the brain when cannabis makes you anxious?

What happens in the brain when cannabis makes you ...

114

Blocking immune cells’ path into brain limits neurodegeneration

Blocking immune cells’ path into brain limits neur...

218

Exposure to common chemicals alter normal breast development

Exposure to common chemicals alter normal breast d...

38

Cigarette smoke may prime lung stem cells for different types of lung cancer

Cigarette smoke may prime lung stem cells for diff...

58

Regulating cellular recycling

Regulating cellular recycling

61

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

73

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

121

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

683

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

115

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

122

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

225

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

133

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

100

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

81

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

113

Hitting two organs with one common signaling regulator

Hitting two organs with one common signaling regul...

423

Microplastics cause fatty liver disease

Microplastics cause fatty liver disease

91

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

444

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

361

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

112

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

96

Mechanism of obesity relapse

Mechanism of obesity relapse

209

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

169

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

148

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

550

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

212

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

244

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

297

AI tool for designing biomolecules with atomic precision

AI tool for designing biomolecules with atomic pre...

558

AI tool identifies new dimension of biological variability in the genome

AI tool identifies new dimension of biological var...

37

AI language models that see every letter

AI language models that see every letter

61

Mapping cellular gene functions with AI and microscopy

Mapping cellular gene functions with AI and micros...

52

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

79

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

617

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

175

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

163

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

256

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

303

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

99

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

97

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

137

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

61

Protein-based data storage

Protein-based data storage

252

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

238

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

258

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

403

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

317

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

360

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

425

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

419

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

375

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

410

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

372

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

451

Signal timing determines cell type balance in the gut

Signal timing determines cell type balance in the gut

187

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

90

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

175

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

145

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

140

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

110

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

149

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

130

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

155

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

152

A novel 3D brain tissue model

A novel 3D brain tissue model

178

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

178

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

163

Genetic differences between humans and chimpanzees

Genetic differences between humans and chimpanzees

122

Heredity is about more than just DNA

Heredity is about more than just DNA

82

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

81

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

174

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

106

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

102

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

91

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

103

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

94

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

107

Generational chromosome repair!

Generational chromosome repair!

103

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

94

Is our personality written in our genes?

Is our personality written in our genes?

197

Controlling aging muscle

Controlling aging muscle

553

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

144

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

100

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

95

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

126

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

161

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

201

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

210

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

191

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

196

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

298

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

319

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

315

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

76

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

99

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

96

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

82

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

99

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

148

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

129

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

121

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

160

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

150

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

155

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

173

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

173

Antifungal treatments during pregnancy linked to changes in foetal hormone production

Antifungal treatments during pregnancy linked to c...

27

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

225

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

189

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

92

Postbiotics may boost female fertility

Postbiotics may boost female fertility

166

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

169

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

180

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

264

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

249

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

279

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

268

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

334

sncRNAs in sperm aging

sncRNAs in sperm aging

387

How a protein complex guards the entrance to channels in mitochondrial membrane cristae

How a protein complex guards the entrance to chann...

46

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

171

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

75

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

3714

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

179

New role for cohesin in DNA replication

New role for cohesin in DNA replication

151

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

87

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

129

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

69

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

84

How a protein shapes the cell membrane

How a protein shapes the cell membrane

91

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

102

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

75

How a bacteria senses iron?

How a bacteria senses iron?

83

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

624

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

55

Alternate pathway of antibiotic resistance

Alternate pathway of antibiotic resistance

67

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

51

How bacteria fight viruses

How bacteria fight viruses

66

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

1129

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

192

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

84

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

84

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

130

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

71

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

88

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

90

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

155

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

84

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

92

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

99

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

102

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

101

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

136

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

195

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

195

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

183

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

182

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

208

How plants read fungal warning signs

How plants read fungal warning signs

50

How plant enzymes learned to tell mirror-image molecules apart

How plant enzymes learned to tell mirror-image mol...

244

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

46

How plants sense touch?

How plants sense touch?

137

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

83

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

81

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

122

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

111

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

126

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

189

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

171

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

190

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

172

Sex difference in immune ageing

Sex difference in immune ageing

109

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

104

Why some people can fight infections better than others?

Why some people can fight infections better than o...

134

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

124

Gene circuits of human immunity

Gene circuits of human immunity

144

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

124

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

140

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

105

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

125

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

124

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

120

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

133

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

124

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

89

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

148

Air-permeable hydrogels!

Air-permeable hydrogels!

177

Temperature behaves differently in the cell

Temperature behaves differently in the cell

174

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

155

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

205

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

230

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

313

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

579

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

477

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

970

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

570

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

581

Less invasive approach to diagnosing mitochondrial disease

Less invasive approach to diagnosing mitochondrial...

48

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

539

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

55

A world-first DNA computer

A world-first DNA computer

58

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

108

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

83

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

113

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

83

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

115

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

116

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

98

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

113

Viral RNA elements functional map!

Viral RNA elements functional map!

110

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

190

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

335

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

518

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

543

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

506

How the brain regulates emotions

How the brain regulates emotions

730

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

600

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

611

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

598

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

576

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

570

Link between dietary choices and brain health

Link between dietary choices and brain health

535

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

531

Research

A roadmap for quantifying metabolism in patients with cancer

A roadmap for quantifying metabolism in patients w...

8

Parvalbumin cell state dynamics regulate gamma oscillations and are disrupted in Alzheimer’s disease

Parvalbumin cell state dynamics regulate gamma osc...

17

Structural basis for size-selective perception of chitin in plants

Structural basis for size-selective perception of ...

26

Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer

Environmental chemical mixtures reprogram mammary ...

25

The gene-regulatory evolution of the human skeleton

The gene-regulatory evolution of the human skeleton

32

Decoding the functional specificity of E2F3 isoforms

Decoding the functional specificity of E2F3 isoforms

24

Innate immune memory in mucosa: where is it encoded?

Innate immune memory in mucosa: where is it encoded?

45

Mesoscale tissue states in fibrosis: from pathway targeting to state-directed therapy

Mesoscale tissue states in fibrosis: from pathway ...

26

Somatic epimutations cap genetic determinism in the human diploid chromatin epigenome

Somatic epimutations cap genetic determinism in th...

30

Distinct functional open states of the polymodal nociceptor TRPV1

Distinct functional open states of the polymodal n...

27

Prenatal antifungal exposure disrupts fetal steroidogenesis and is associated with persistent effects in children

Prenatal antifungal exposure disrupts fetal steroi...

30

Comprehensive functional testing in fibroblasts has strong utility to diagnose mitochondrial disease

Comprehensive functional testing in fibroblasts ha...

24

Integrative structural modelling reveals the human Mic60-Mic19 subcomplex as a diffusion barrier in mitochondria

Integrative structural modelling reveals the human...

27

A roadmap for quantifying metabolism in patients with cancer

A roadmap for quantifying metabolism in patients w...

8

Parvalbumin cell state dynamics regulate gamma oscillations and are disrupted in Alzheimer’s disease

Parvalbumin cell state dynamics regulate gamma osc...

17

Structural basis for size-selective perception of chitin in plants

Structural basis for size-selective perception of ...

26

Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer

Environmental chemical mixtures reprogram mammary ...

25

The gene-regulatory evolution of the human skeleton

The gene-regulatory evolution of the human skeleton

32

Decoding the functional specificity of E2F3 isoforms

Decoding the functional specificity of E2F3 isoforms

24

Innate immune memory in mucosa: where is it encoded?

Innate immune memory in mucosa: where is it encoded?

45

Mesoscale tissue states in fibrosis: from pathway targeting to state-directed therapy

Mesoscale tissue states in fibrosis: from pathway ...

26

Somatic epimutations cap genetic determinism in the human diploid chromatin epigenome

Somatic epimutations cap genetic determinism in th...

30

Distinct functional open states of the polymodal nociceptor TRPV1

Distinct functional open states of the polymodal n...

27

Prenatal antifungal exposure disrupts fetal steroidogenesis and is associated with persistent effects in children

Prenatal antifungal exposure disrupts fetal steroi...

30

Comprehensive functional testing in fibroblasts has strong utility to diagnose mitochondrial disease

Comprehensive functional testing in fibroblasts ha...

24

Integrative structural modelling reveals the human Mic60-Mic19 subcomplex as a diffusion barrier in mitochondria

Integrative structural modelling reveals the human...

27

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular phenoty...

45

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex image-...

47

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

111

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

71

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

84

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

71

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

108

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

104

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

122

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

206

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

111

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

95

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

81

Breeding of Cotton

Breeding of Cotton

768

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

1010

THALASSEMIA

THALASSEMIA

1109

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

1119

NMDA RECEPTORS

500

Neural Development

Neural Development

488

Transcription Factors

Transcription Factors

479

Interferons

426

RABIES

440

ANEMIA

453

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

426

Migraine

357

Dementia

452

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

73

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

78

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

101

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

11660

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

67

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

91

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

2979

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

141

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

123

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

102

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2396

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

68

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

116

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

554

Gestational diabetes therapeutics

Gestational diabetes therapeutics

649

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

600

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

947

Different types of Alzheimer's disease

Different types of Alzheimer's disease

705

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

633

Alzheimer’s therapeutics

Alzheimer’s therapeutics

795

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

680

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

684

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

621

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

619

APOE in Alzheimer’s

APOE in Alzheimer’s

849

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

774

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

947

Different types of Alzheimer's disease

Different types of Alzheimer's disease

705

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

633

Alzheimer’s therapeutics

Alzheimer’s therapeutics

795

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

680

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

684

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

621

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

619

APOE in Alzheimer’s

APOE in Alzheimer’s

849

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

774

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

589

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

789

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

573

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

554

Gestational diabetes therapeutics

Gestational diabetes therapeutics

649

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

600