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All Publications Protocols Presentations Posters
The Human Ovary Exhibits Dynamic Molecular Remodeling in the Decades Post-Menopause

The Human Ovary Exhibits Dynamic Molecular Re...

 15

Evidence for maternal autoantibodies in the pathogenesis of preterm birth

Evidence for maternal autoantibodies in the p...

 22

Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance

Stearoyl-CoA desaturases regulate intestinal ...

 26

Ki-67, the chromosome periphery and de- compartmentalisation each contribute to  nucleophosmin mislocalisation in acute myeloid leukaemia

Ki-67, the chromosome periphery and de- compa...

 24

The Human Ovary Exhibits Dynamic Molecular Remodeling in the Decades Post-Menopause

The Human Ovary Exhibits Dynamic Molecular Re...

 15

Evidence for maternal autoantibodies in the pathogenesis of preterm birth

Evidence for maternal autoantibodies in the p...

 22

Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance

Stearoyl-CoA desaturases regulate intestinal ...

 26

Ki-67, the chromosome periphery and de- compartmentalisation each contribute to  nucleophosmin mislocalisation in acute myeloid leukaemia

Ki-67, the chromosome periphery and de- compa...

 24

Comprehensive benchmarking of somatic mutation detection by the SMaHT Network

Comprehensive benchmarking of somatic mutatio...

 82

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular ph...

 216

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex i...

 105

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial ...

 179

Breeding of Cotton

Breeding of Cotton

 819

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 1094

THALASSEMIA

THALASSEMIA

 1164

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1177

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurol...

 120

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for canc...

 137

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-F...

 161

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrang...

 14216

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Science Hangouts

Dimerization and activation of receptor tyrosine kinases:  insights from quantitative fluorescence studies
Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

 16785

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty
Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

 120

Systems Biology & Medicine: Markers, Mechanisms and Pathways
Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

 140

Novel Anti-inflammatory Bioactive Lipids from the CYP epoxygenase Pathway
Science Hangouts

Novel Anti-inflammatory Bioactive Lipids from the CYP epoxygenase Pathway

 37

Science News Highlights

The recipe for intelligence in natural and artificial systems
News highlights

The recipe for intelligence in natural and artificial systems

 19

 Structure of Mg2+ transport protein, CNNM4 unraveled!
News highlights

 Structure of Mg2+ transport protein, CNNM4 unraveled!

 15

What is cancer cartography?
News highlights

What is cancer cartography?

 23

News

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The postmenopausal ovary is not defunct!

The postmenopausal ovary is not defunct!

 93

Linking maternal autoantibodies to premature birth

Linking maternal autoantibodies to premature birth

 27

Mechanism driving aggressive leukemia uncovered!

Mechanism driving aggressive leukemia uncovered!

 64

AI detects regions around 'microexons' involved in genetic variation in autism

AI detects regions around 'microexons' involved in...

 35

AI based study demonstrates stimulation of brown fat by blood-pressure drug

AI based study demonstrates stimulation of brown f...

 36

Activating just 20 neurons trigger learned movements 

Activating just 20 neurons trigger learned movements 

 16

AI identifies a regulator of aging

AI identifies a regulator of aging

 659

Breast milk antibodies show broad antiviral activity and protect mice against influenza

Breast milk antibodies show broad antiviral activi...

 52

Skin stem cell renewal shows sexual dimorphism

Skin stem cell renewal shows sexual dimorphism

 236

Mammals produce cyclo-octasulfur to protect cells from lipid damage

Mammals produce cyclo-octasulfur to protect cells ...

 146

Nerve and immune cells interact to fuel pain in endometriosis

Nerve and immune cells interact to fuel pain in en...

 170

Alcohol and the brain interact through immune cells

Alcohol and the brain interact through immune cells

 191

Achilles' heel of antibiotic-resistant bacteria discovered

Achilles' heel of antibiotic-resistant bacteria di...

 307

Activating just 20 neurons trigger learned movements 

Activating just 20 neurons trigger learned movements 

 16

Alcohol and the brain interact through immune cells

Alcohol and the brain interact through immune cells

 191

Treating depression during pregnancy may benefit babies' brain development

Treating depression during pregnancy may benefit b...

 50

Secreted phospholipase confers neuroprotection and cognitive resilience during aging

Secreted phospholipase confers neuroprotection and...

 51

Opioid painkiller platform to turn ‘on’ or ‘off’ with light

Opioid painkiller platform to turn ‘on’ or ‘off’ w...

 64

How critical brain cells misfire in Alzheimer's

How critical brain cells misfire in Alzheimer's

 716

Capsaicin receptor, TRPV1, responds differently to varying triggers

Capsaicin receptor, TRPV1, responds differently to...

 265

Reducing pathological pain!

Reducing pathological pain!

 73

Effect of processed food on brain metabolism and function

Effect of processed food on brain metabolism and f...

 108

Viral infections can accelerate the progression of ALS

Viral infections can accelerate the progression of...

 111

Rectifying autism-associated endothelial dysfunction

Rectifying autism-associated endothelial dysfunction

 114

A single neuron type enables learning of motor timing

A single neuron type enables learning of motor timing

 85

How gut bacteria can shape the brain’s response to stroke

How gut bacteria can shape the brain’s response to...

 149

Mechanism driving aggressive leukemia uncovered!

Mechanism driving aggressive leukemia uncovered!

 64

Exposure to common chemicals alter normal breast development

Exposure to common chemicals alter normal breast d...

 76

Cigarette smoke may prime lung stem cells for different types of lung cancer

Cigarette smoke may prime lung stem cells for diff...

 94

Regulating cellular recycling

Regulating cellular recycling

 81

How cells respond differently to a cancer-causing gene

How cells respond differently to a cancer-causing ...

 90

Cachexia-promoting microenvironment in pancreatic cancer

Cachexia-promoting microenvironment in pancreatic ...

 139

Distinct gut microbiome patterns found in 5 cancer groups and in early-onset cancers

Distinct gut microbiome patterns found in 5 cancer...

 700

How loss of tumor suppressor p53 enables mutant cells proliferate through normal tissue?

How loss of tumor suppressor p53 enables mutant ce...

 130

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

 139

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

 245

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

 152

Cancer-linked protein binds to chromosome in unexpected way 

Cancer-linked protein binds to chromosome in unexp...

 119

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

 96

Hitting two organs with one common signaling regulator

Hitting two organs with one common signaling regul...

 446

Microplastics cause fatty liver disease 

Microplastics cause fatty liver disease 

 109

Exercise rewires liver metabolism differently based on sex

Exercise rewires liver metabolism differently base...

 461

A mitochondrial carrier syncs body clock, our diet and the temperature around us

A mitochondrial carrier syncs body clock, our diet...

 380

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

 126

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

 111

Mechanism of obesity relapse

Mechanism of obesity relapse

 224

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

 182

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

 160

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

 564

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

 224

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

 258

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

 317

AI identifies a regulator of aging

AI identifies a regulator of aging

 659

AI tool for designing biomolecules with atomic precision

AI tool for designing biomolecules with atomic pre...

 1512

AI tool identifies new dimension of biological variability in the genome

AI tool identifies new dimension of biological var...

 55

AI language models that see every letter

AI language models that see every letter

 90

Mapping cellular gene functions with AI and microscopy

Mapping cellular gene functions with AI and micros...

 72

New machine-learning method reveals what can make bacteria dangerous

New machine-learning method reveals what can make ...

 97

Proteomics and AI structure prediction to speed up ‘molecular glues’ discovery

Proteomics and AI structure prediction to speed up...

 642

AI detects signs of aging in blood stem cells from nuclear images

AI detects signs of aging in blood stem cells from...

 193

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

 176

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

 277

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

 326

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

 116

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

 110

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

 77

Protein-based data storage

Protein-based data storage

 265

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

 257

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

 272

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

 416

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

 327

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

 371

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 442

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 430

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 387

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 426

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 384

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 462

Skin stem cell renewal shows sexual dimorphism

Skin stem cell renewal shows sexual dimorphism

 236

Signal timing determines cell type balance in the gut

Signal timing determines cell type balance in the gut

 270

Growing salivary glands from pluripotent stem cells

Growing salivary glands from pluripotent stem cells

 107

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

 192

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

 157

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

 158

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

 127

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

 163

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

 143

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

 165

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

 168

A novel 3D brain tissue model

A novel 3D brain tissue model

 191

EV  secretome to treat cardiac fibrosis

EV  secretome to treat cardiac fibrosis

 195

AI detects regions around 'microexons' involved in genetic variation in autism

AI detects regions around 'microexons' involved in...

 35

Detecting DNA mutations across the human genome

Detecting DNA mutations across the human genome

 149

Genetic differences between humans and chimpanzees

Genetic differences between humans and chimpanzees

 305

Heredity is about more than just DNA

Heredity is about more than just DNA

 126

Amoeba’s mitochondrial metabolism!

Amoeba’s mitochondrial metabolism!

 101

Sex chromosomes drive how bodies deal with cancer, heart health and longevity

Sex chromosomes drive how bodies deal with cancer,...

 185

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

 119

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

 115

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

 104

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

 115

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

 105

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

 119

Generational chromosome repair!

Generational chromosome repair!

 118

Why exercise is good for us?

Why exercise is good for us?

 105

How cellular self-organization steers and stops waves of cell death

How cellular self-organization steers and stops wa...

 71

Controlling aging muscle

Controlling aging muscle

 567

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

 157

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

 113

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

 113

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

 138

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

 175

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

 217

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

 222

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

 208

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

 207

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

 314

AI based study demonstrates stimulation of brown fat by blood-pressure drug

AI based study demonstrates stimulation of brown f...

 36

Linking cardiac failure to inflammatory reprogramming by bone marrow cells

Linking cardiac failure to inflammatory reprogramm...

 80

Newly discovered cell helps shape blood vessel growth in the heart

Newly discovered cell helps shape blood vessel gro...

 89

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

 119

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

 110

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

 92

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

 112

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

 168

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

 143

Capillaries and not arteries give rise to  backup blood vessels

Capillaries and not arteries give rise to backup ...

 134

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

 173

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

 161

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

 167

The postmenopausal ovary is not defunct!

The postmenopausal ovary is not defunct!

 93

Linking maternal autoantibodies to premature birth

Linking maternal autoantibodies to premature birth

 27

Nerve and immune cells interact to fuel pain in endometriosis

Nerve and immune cells interact to fuel pain in en...

 170

Nicotine exposure during pregnancy increases flu severity later in life

Nicotine exposure during pregnancy increases flu s...

 89

Antifungal treatments during pregnancy linked to changes in foetal hormone production

Antifungal treatments during pregnancy linked to c...

 48

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

 238

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

 201

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

 103

Postbiotics may boost female fertility

Postbiotics may boost female fertility

 177

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

 178

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

 188

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

 283

Aging human breast atlas reveals  cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

 264

Mammals produce cyclo-octasulfur to protect cells from lipid damage

Mammals produce cyclo-octasulfur to protect cells ...

 146

The shape of water defines the hotspot that starts protein aggregation in dementia

The shape of water defines the hotspot that starts...

 110

How a protein complex guards the entrance to channels in mitochondrial membrane cristae

How a protein complex guards the entrance to chann...

 69

Why “zombie cells” accumulate with age

Why “zombie cells” accumulate with age

 264

Visualizing genome targeting of linker histone’s

Visualizing genome targeting of linker histone’s

 89

How exercise protects joints in aging-related osteoarthritis

How exercise protects joints in aging-related oste...

 3728

Computer-designed protein targets immune receptor linked to inflammation at a new “undruggable” site

Computer-designed protein targets immune receptor ...

 191

New role for cohesin in DNA replication

New role for cohesin in DNA replication

 162

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

 96

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

 141

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

 81

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

 94

How a protein shapes the cell membrane

How a protein shapes the cell membrane

 101

Achilles' heel of antibiotic-resistant bacteria discovered

Achilles' heel of antibiotic-resistant bacteria di...

 307

New mechanism for Candida auris to resist antifungal treatment

New mechanism for Candida auris to resist antifung...

 148

How a bacteria senses iron?

How a bacteria senses iron?

 97

The human gut microbiome shapes vaccine side effects

The human gut microbiome shapes vaccine side effects

 660

How non-enveloped viruses infect cells

How non-enveloped viruses infect cells

 66

Alternate pathway of antibiotic resistance 

Alternate pathway of antibiotic resistance 

 77

A computational tool for accurate taxonomic profiling

A computational tool for accurate taxonomic profiling

 63

How bacteria fight viruses

How bacteria fight viruses

 80

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

 1144

 How Epstein-Barr Virus triggers multiple sclerosis relapse

 How Epstein-Barr Virus triggers multiple sclerosi...

 204

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

 97

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

 99

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

 138

Mapping mouse single cell zygote to late organogenesis using DNA Typewriter

Mapping mouse single cell zygote to late organogen...

 111

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

 162

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

 96

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

 101

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

 107

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

 112

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

 113

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

 147

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

 205

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

 207

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

 192

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

 188

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

 218

How plants read fungal warning signs

How plants read fungal warning signs

 188

How plant enzymes learned to tell mirror-image molecules apart

How plant enzymes learned to tell mirror-image mol...

 256

How plant roots acquire iron by interacting with bacteria

How plant roots acquire iron by interacting with b...

 68

How plants sense touch?

How plants sense touch?

 150

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

 96

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

 94

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

 134

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

 119

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

 137

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

 201

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

 182

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

 201

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

 187

Breast milk antibodies show broad antiviral activity and protect mice against influenza

Breast milk antibodies show broad antiviral activi...

 52

Sex difference in immune ageing

Sex difference in immune ageing

 121

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

 118

Why some people can fight infections better than others?

Why some people can fight infections better than o...

 145

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

 141

Gene circuits of human immunity

Gene circuits of human immunity

 155

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

 135

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

 150

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

 114

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

 135

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

 132

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

 132

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

 144

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

 106

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

 165

Air-permeable hydrogels!

Air-permeable hydrogels!

 189

Temperature behaves differently in the cell

Temperature behaves differently in the cell

 181

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

 167

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

 218

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

 238

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

 326

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 589

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 490

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 984

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 578

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 599

Less invasive approach to diagnosing mitochondrial disease 

Less invasive approach to diagnosing mitochondrial...

 70

New platform maps gene activity and metabolites in the same tissue sample

New platform maps gene activity and metabolites in...

 549

Mass spectrometry offers faster look at the edges of brain tumors

Mass spectrometry offers faster look at the edges ...

 67

A world-first DNA computer 

A world-first DNA computer 

 66

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

 123

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

 98

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

 127

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

 94

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

 123

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

 128

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

 105

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

 121

Viral RNA elements functional map!

Viral RNA elements functional map!

 120

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

 205

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 345

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 532

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 556

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 523

How the brain regulates emotions

How the brain regulates emotions

 743

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 613

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 627

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 612

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 588

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 580

Link between dietary choices and brain health

Link between dietary choices and brain health

 546

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 539

Research

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    • Publications
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    • Posters
The Human Ovary Exhibits Dynamic Molecular Remodeling in the Decades Post-Menopause

The Human Ovary Exhibits Dynamic Molecular Remodel...

 15

Evidence for maternal autoantibodies in the pathogenesis of preterm birth

Evidence for maternal autoantibodies in the pathog...

 22

Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance

Stearoyl-CoA desaturases regulate intestinal stem ...

 26

Ki-67, the chromosome periphery and de- compartmentalisation each contribute to  nucleophosmin mislocalisation in acute myeloid leukaemia

Ki-67, the chromosome periphery and de- compartmen...

 24

A microexon regulatory code reveals autism-linked genetic variation

A microexon regulatory code reveals autism-linked ...

 36

Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phenotypi...

 25

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling drives ...

 57

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and artific...

 35

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines Mg2+ ...

 30

Polyclonal breast milk–derived secretory IgA confers broad antiviral protection against multiple respiratory viruses

Polyclonal breast milk–derived secretory IgA confe...

 684

Sexual dimorphism in epidermal stem cell dynamics

Sexual dimorphism in epidermal stem cell dynamics

 32

High-resolution spatial transcriptomics reveals fibroblast and neuroimmune microenvironments in endometriosis lesions

High-resolution spatial transcriptomics reveals fi...

 27

Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse

Microglia-mediated extracellular matrix disruption...

 41

The Human Ovary Exhibits Dynamic Molecular Remodeling in the Decades Post-Menopause

The Human Ovary Exhibits Dynamic Molecular Remodel...

 15

Evidence for maternal autoantibodies in the pathogenesis of preterm birth

Evidence for maternal autoantibodies in the pathog...

 22

Stearoyl-CoA desaturases regulate intestinal stem and progenitor cell metabolism and function in response to nutrient abundance

Stearoyl-CoA desaturases regulate intestinal stem ...

 26

Ki-67, the chromosome periphery and de- compartmentalisation each contribute to  nucleophosmin mislocalisation in acute myeloid leukaemia

Ki-67, the chromosome periphery and de- compartmen...

 24

A microexon regulatory code reveals autism-linked genetic variation

A microexon regulatory code reveals autism-linked ...

 36

Artificial intelligence-enabled clinical phenotyping of human brown fat

Artificial intelligence-enabled clinical phenotypi...

 25

Maternal-fetal type I interferon signaling drives TREM2 dysregulation and synaptic dysfunction in neurodevelopmental disorders

Maternal-fetal type I interferon signaling drives ...

 57

The recipe for intelligence in natural and artificial systems

The recipe for intelligence in natural and artific...

 35

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

Dynamic dimer-of-dimers architecture defines Mg2+ ...

 30

Polyclonal breast milk–derived secretory IgA confers broad antiviral protection against multiple respiratory viruses

Polyclonal breast milk–derived secretory IgA confe...

 684

Sexual dimorphism in epidermal stem cell dynamics

Sexual dimorphism in epidermal stem cell dynamics

 32

High-resolution spatial transcriptomics reveals fibroblast and neuroimmune microenvironments in endometriosis lesions

High-resolution spatial transcriptomics reveals fi...

 27

Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse

Microglia-mediated extracellular matrix disruption...

 41

Comprehensive benchmarking of somatic mutation detection by the SMaHT Network

Comprehensive benchmarking of somatic mutation det...

 82

Tahoe-100M: Mapping drug-induced molecular phenotypes at single-cell resolution

Tahoe-100M: Mapping drug-induced molecular phenoty...

 216

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening

SPARCS enables scalable recovery of complex image-...

 105

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

 179

scBaseCount: An AI agent-curated, standardized, auto-updated single-cell data repository

scBaseCount: An AI agent-curated, standardized, au...

 82

Metabolite ratiomics: Rapid diagnosis and classification of gliomas for intraoperative application during brain surgery

Metabolite ratiomics: Rapid diagnosis and classifi...

 94

Quantum computing for biotechnological innovation: transformative potential in biomedicine and drug discovery

Quantum computing for biotechnological innovation:...

 83

Tracking newly synthesised proteins in plants

Tracking newly synthesised proteins in plants

 119

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

 116

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

 137

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

 217

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

 123

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

 104

Breeding of Cotton

Breeding of Cotton

 819

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

 1094

THALASSEMIA

THALASSEMIA

 1164

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

 1177

NMDA RECEPTORS

NMDA RECEPTORS

 510

Neural Development

Neural Development

 497

Transcription Factors

Transcription Factors

 490

Interferons

Interferons

 434

RABIES

RABIES

 454

ANEMIA

ANEMIA

 466

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

 438

Migraine

Migraine

 366

Dementia

Dementia

 464

Deciphering DHX9 gene pathogenicity in neurological disorders with distinct phenotypes

Deciphering DHX9 gene pathogenicity in neurologica...

 120

DrBioRight: an AI research assistant for cancer data analysis

DrBioRight: an AI research assistant for cancer da...

 137

Cancer Phenotypes of Hypomorphic versus Non-Functional TP53 Variants in Li-Fraumeni Syndrome

Cancer Phenotypes of Hypomorphic versus Non-Functi...

 161

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

 14216

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

 81

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

 101

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

 2993

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

 151

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

 135

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

 110

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

 2405

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

 77

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

 131

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 562

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 658

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 608

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 953

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 712

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 640

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 808

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 696

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 700

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 638

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 634

APOE in Alzheimer’s

APOE in Alzheimer’s

 868

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 789

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 953

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 712

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 640

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 808

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 696

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 700

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 638

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 634

APOE in Alzheimer’s

APOE in Alzheimer’s

 868

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 789

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 595

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 805

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 589

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 562

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 658

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 608

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