Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

7176

Motivation and Pleasure in Psychosis?

Science Hangouts

Motivation and Pleasure in Psychosis?

6

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

Science Hangouts

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

4

Science News Highlights

Micro eye movements and working memory

News highlights

Micro eye movements and working memory

7

Modulating local immunity by tissue-resident regulatory T cells

News highlights

Modulating local immunity by tissue-resident regulator...

7

Microbial proteins as new-generation therapeutic agents

News highlights

Microbial proteins as new-generation therapeutic agents

9

News

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

16

Mitigating Huntington disease by targeting inflammatory pathway

Mitigating Huntington disease by targeting inflamm...

14

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

10

A neuronal receptor complex with distinctive properties

A neuronal receptor complex with distinctive prope...

24

Body clock found to control inflammatory responses in macrophages

Body clock found to control inflammatory responses...

41

Bain histamine neurons gate moment-to-moment memory access

Bain histamine neurons gate moment-to-moment memor...

28

Collagen forms condensate inside cells

Collagen forms condensate inside cells

43

Socioeconomic factors influence children’s brain structure and function

Socioeconomic factors influence children’s brain s...

36

A gut-brain pathway sends weaker fructose signal to the brain than glucose

A gut-brain pathway sends weaker fructose signal t...

43

Telomeres and centromeres interact in some aggressive cancers

Telomeres and centromeres interact in some aggress...

31

A targeted RNA cleavage and repair method, to fix dysfunctional RNA

A targeted RNA cleavage and repair method, to fix ...

30

Engineered Salmonella bacteria to treat solid tumors

Engineered Salmonella bacteria to treat solid tumors

24

Link between stress hormone and brain plasticity in early life

Link between stress hormone and brain plasticity i...

43

Mitigating Huntington disease by targeting inflammatory pathway

Mitigating Huntington disease by targeting inflamm...

14

A neuronal receptor complex with distinctive properties

A neuronal receptor complex with distinctive prope...

24

Bain histamine neurons gate moment-to-moment memory access

Bain histamine neurons gate moment-to-moment memor...

28

Socioeconomic factors influence children’s brain structure and function

Socioeconomic factors influence children’s brain s...

36

A gut-brain pathway sends weaker fructose signal to the brain than glucose

A gut-brain pathway sends weaker fructose signal t...

43

Link between stress hormone and brain plasticity in early life

Link between stress hormone and brain plasticity i...

43

Brain circuit regulating the timing of torpor identified!

Brain circuit regulating the timing of torpor iden...

30

New reference map of the brain!

New reference map of the brain!

79

Copper imbalance in autism

Copper imbalance in autism

56

Two distinct subtypes of autism with different underlying biology

Two distinct subtypes of autism with different und...

39

Neutrophils manufacture C4 protein in schizophrenia

Neutrophils manufacture C4 protein in schizophrenia

57

Microglia dysfunction in multiple system atrophy

Microglia dysfunction in multiple system atrophy

85

Mechanisms of calcium permeability and magnesium block in NMDA receptors

Mechanisms of calcium permeability and magnesium b...

80

Telomeres and centromeres interact in some aggressive cancers

Telomeres and centromeres interact in some aggress...

31

Engineered Salmonella bacteria to treat solid tumors

Engineered Salmonella bacteria to treat solid tumors

24

Gene linking the trade-off between youth and longevity uncovered!

Gene linking the trade-off between youth and longe...

33

Blood test detects early signs of breast cancer recurrence

Blood test detects early signs of breast cancer re...

44

Nervous system helps lung cancer evade the immune system

Nervous system helps lung cancer evade the immune ...

31

How chemotherapy influences cancer inflammation

How chemotherapy influences cancer inflammation

52

DNA repair protein creates DNA damage similar to BRCA mutations

DNA repair protein creates DNA damage similar to B...

82

Selective degradation of proteins involved in pathological processes

Selective degradation of proteins involved in path...

77

Testosterone slows brain tumor growth

Testosterone slows brain tumor growth

80

How an enzyme affects infertility and cancer progression

How an enzyme affects infertility and cancer progr...

67

How gut bacteria toxin invades colon cells to trigger cancer

How gut bacteria toxin invades colon cells to trig...

72

New method reveals tumor environment that favor metastatic growth

New method reveals tumor environment that favor me...

101

Developing tumor microenvironment for cancer growth

Developing tumor microenvironment for cancer growth

81

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

66

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

98

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

98

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

87

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

103

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

113

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

128

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

113

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

116

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

140

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

155

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

245

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

161

A blood signature for lung cancer risk

A blood signature for lung cancer risk

59

MouseMapper AI reveals hidden whole-body-damage caused by obesity

MouseMapper AI reveals hidden whole-body-damage ca...

68

AI to design miniproteins targeting GPCRs

AI to design miniproteins targeting GPCRs

74

AI tool to bridge gene regulation and cell fate decisions

AI tool to bridge gene regulation and cell fate de...

141

Genetics of blood proteins!

Genetics of blood proteins!

48

FaceAge AI tool predicts cancer patients survival

FaceAge AI tool predicts cancer patients survival

54

A potassium-gated ion channel identified!

A potassium-gated ion channel identified!

88

AI model for protein-protein interaction modeling

AI model for protein-protein interaction modeling

103

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

167

Gene signature predicting lung cancer recurrence

Gene signature predicting lung cancer recurrence

116

Bio-bank data analysis links genetics to disease risk and treatment response

Bio-bank data analysis links genetics to disease r...

115

Computational model measures telomere shortening from routine biopsies

Computational model measures telomere shortening f...

121

AI tool to predict heart diseases 15 years in advance

AI tool to predict heart diseases 15 years in advance

126

Protein-based data storage

Protein-based data storage

39

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

54

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

64

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

188

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

138

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

175

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

231

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

216

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

203

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

244

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

217

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

251

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

264

Reversing nerve damage in human corticospinal organoid-slice connectoid model

Reversing nerve damage in human corticospinal orga...

36

Zinc finger proteins act on gene promoters to control differentiation of stem cells

Zinc finger proteins act on gene promoters to cont...

49

Identifying the ‘organizer’ cells that build bone marrow

Identifying the ‘organizer’ cells that build bone ...

60

Not all Alzheimer’s leads to dementia

Not all Alzheimer’s leads to dementia

83

What keeps vision cells alive?

What keeps vision cells alive?

148

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

88

A long-term and scalable system to record from neural organoids

A long-term and scalable system to record from neu...

92

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

128

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

144

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

148

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

281

How cell walls guide stem cells

How cell walls guide stem cells

183

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

171

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

30

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

38

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

68

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

94

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

88

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

116

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

131

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

114

How longevity is inherited across generations

How longevity is inherited across generations

180

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

135

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

169

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

141

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

127

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

10

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

123

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

155

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

162

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

194

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

486

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

497

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

483

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

559

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

383

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

451

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

587

Role of ECM in brain memory

Role of ECM in brain memory

528

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

16

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

32

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

33

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

60

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

55

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

84

Mechanisms of aortic aneurysm progression

Mechanisms of aortic aneurysm progression

56

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

156

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

117

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

134

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

125

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

133

A novel inflammatory function of platelets

A novel inflammatory function of platelets

147

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

58

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

87

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

119

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

115

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

151

sncRNAs in sperm aging

sncRNAs in sperm aging

171

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

179

How reproductive organs form

How reproductive organs form

209

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

171

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

176

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

208

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

251

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

212

Collagen forms condensate inside cells

Collagen forms condensate inside cells

43

A targeted RNA cleavage and repair method, to fix dysfunctional RNA

A targeted RNA cleavage and repair method, to fix ...

30

Role of condensates in signaling

Role of condensates in signaling

67

How acid removes water from proteins

How acid removes water from proteins

44

How the protein interact to send the inflammatory signals

How the protein interact to send the inflammatory ...

70

How cells restart protein synthesis after awakening from dormant stste

How cells restart protein synthesis after awakenin...

48

Friedreich’s ataxia reveals how DNA folding can silence a key gene

Friedreich’s ataxia reveals how DNA folding can si...

40

Mechanism of protein polymerization in the cells

Mechanism of protein polymerization in the cells

39

New proteins revealed in dark proteome

New proteins revealed in dark proteome

62

A new kind of cold sensor

A new kind of cold sensor

65

Childhood brain diseases from mutations in tubulin co-factors

Childhood brain diseases from mutations in tubulin...

51

Zinc-Redox crosstalk to control protein quality

Zinc-Redox crosstalk to control protein quality

56

New mechanisms of oncogenic fusion protein activation and signaling

New mechanisms of oncogenic fusion protein activat...

64

A new natural depsipeptide antibiotic discovered!

A new natural depsipeptide antibiotic discovered!

12

How cells fight infection from the inside

How cells fight infection from the inside

37

Gut microbe found to worsen sepsis

Gut microbe found to worsen sepsis

35

A link between autoantibodies and neurological symptoms in long COVID

A link between autoantibodies and neurological sym...

31

Microbiome restructuring associated with medical exposure

Microbiome restructuring associated with medical e...

36

HIV-1 remodels nuclear pores to infect immune cells

HIV-1 remodels nuclear pores to infect immune cells

69

Myocarditis after mRNA vaccination is attributed to mitochondrial stress

Myocarditis after mRNA vaccination is attributed t...

59

Engineered bacteria to treat liver-related brain dysfunction

Engineered bacteria to treat liver-related brain d...

73

How pathogens switch on their virulence

How pathogens switch on their virulence

58

Disease-causing pathogen rewires gut metabolism to grow

Disease-causing pathogen rewires gut metabolism to...

62

Pro- and anti-HIV host factors in T cells

Pro- and anti-HIV host factors in T cells

64

A new way coronaviruses can get into human cells

A new way coronaviruses can get into human cells

71

How caspofungin inhibits fungal infection?

How caspofungin inhibits fungal infection?

68

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

53

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

38

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

41

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

72

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

54

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

58

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

74

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

80

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

86

A developmental atlas for genes and cells

A developmental atlas for genes and cells

125

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

150

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

123

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

224

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

24

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

32

Cure for dry eye disease

Cure for dry eye disease

52

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

53

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

96

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

73

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

75

Nicotine Biosynthesis!

Nicotine Biosynthesis!

132

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

109

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

171

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

100

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

110

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

176

Body clock found to control inflammatory responses in macrophages

Body clock found to control inflammatory responses...

41

How the body remembers the tumor?

How the body remembers the tumor?

76

Molecular mechanisms to maintain intestinal barrier function

Molecular mechanisms to maintain intestinal barrie...

65

Reversing chromatin aging with SIRT6 overexpression

Reversing chromatin aging with SIRT6 overexpression

118

Molecule linked to treatment-resistant inflammatory bowel disease identified!

Molecule linked to treatment-resistant inflammator...

51

A key protein in the inflammatory response to infections identified

A key protein in the inflammatory response to infe...

58

Proper protein recycling helps exhausted immune cells fight tumors

Proper protein recycling helps exhausted immune ce...

63

How immune cell networks drive liver disease

How immune cell networks drive liver disease

73

NO-independent inflammatory response by iNOS

NO-independent inflammatory response by iNOS

70

Stromal-immune cell circuit in human lymph nodes

Stromal-immune cell circuit in human lymph nodes

94

Mitochondria keep immune cells “ready to respond”

Mitochondria keep immune cells “ready to respond”

89

How the immune system rewrites rapid aging

How the immune system rewrites rapid aging

87

Mutations in immune cells linked to autoimmune diseases

Mutations in immune cells linked to autoimmune dis...

91

Temperature behaves differently in the cell

Temperature behaves differently in the cell

32

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

41

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

77

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

84

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

174

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

457

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

353

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

812

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

443

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

425

Printed skin to replace animal testing

Printed skin to replace animal testing

424

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

407

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

428

Gene transcription measurement in the living brain

Gene transcription measurement in the living brain

46

How the brain takes out its trash

How the brain takes out its trash

54

Single-cell method for mapping DNA-protein interactions

Single-cell method for mapping DNA-protein interac...

73

Ultrasound to alter how the brain responds to pain

Ultrasound to alter how the brain responds to pain

54

Surprising cellular dynamics of the aging brain

Surprising cellular dynamics of the aging brain

105

New CRISPR tool eliminates undesired cells

New CRISPR tool eliminates undesired cells

78

Multiplexed MRI provides a comprehensive view of the human brain

Multiplexed MRI provides a comprehensive view of t...

73

“Aging clocks” to measure body decline

“Aging clocks” to measure body decline

61

“MitoCatch” delivers healthy mitochondria to diseased cells

“MitoCatch” delivers healthy mitochondria to disea...

124

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

88

How the body senses cold

How the body senses cold

157

New computational biology for genome sequencing analysis

New computational biology for genome sequencing an...

126

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

132

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

192

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

384

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

383

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

384

How the brain regulates emotions

How the brain regulates emotions

531

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

457

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

440

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

490

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

457

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

457

Link between dietary choices and brain health

Link between dietary choices and brain health

436

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

403

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

521

Research

Looking into working memory through micro eye movements

Looking into working memory through micro eye move...

7

Tissue-resident regulatory T cells: modulators of local immunity

Tissue-resident regulatory T cells: modulators of ...

7

Convergent molecular signatures across eating disorders and obsessive-compulsive disorder in the human brain

Convergent molecular signatures across eating diso...

15

Targeting the cGAS–STING pathway mitigates Huntington disease pathogenesis in a knock-in mouse model

Targeting the cGAS–STING pathway mitigates Hunting...

7

Myosin light chain proteins cooperatively promote sarcomere growth in fast-twitch muscle

Myosin light chain proteins cooperatively promote ...

10

Structures of partially occupied hetero- tetramers provide insight into kainate receptor activation and desensitization

Structures of partially occupied hetero- tetramers...

8

Repurposing of microbial proteins as new-generation therapeutic agents for biomedical applications

Repurposing of microbial proteins as new-generatio...

24

Persistent and transient senescent cells contribute to brain-barrier development

Persistent and transient senescent cells contribut...

27

The circadian clock component BMAL1 enhances macrophage inflammation by nuclear translocation of peroxisomal β-oxidation enzyme MFP2

The circadian clock component BMAL1 enhances macro...

27

Infraslow histaminergic dynamics govern priming states to gate moment-to-moment memory accessibility

Infraslow histaminergic dynamics govern priming st...

23

Procollagen 1 assembles into phase-separated condensates in the endoplasmic reticulum

Procollagen 1 assembles into phase-separated conde...

22

Understanding and targeting erythroid cell metabolism

Understanding and targeting erythroid cell metabolism

27

Attenuated hypothalamic response to fructose via a dedicated gut-brain pathway

Attenuated hypothalamic response to fructose via a...

28

Looking into working memory through micro eye movements

Looking into working memory through micro eye move...

7

Tissue-resident regulatory T cells: modulators of local immunity

Tissue-resident regulatory T cells: modulators of ...

7

Convergent molecular signatures across eating disorders and obsessive-compulsive disorder in the human brain

Convergent molecular signatures across eating diso...

15

Targeting the cGAS–STING pathway mitigates Huntington disease pathogenesis in a knock-in mouse model

Targeting the cGAS–STING pathway mitigates Hunting...

7

Myosin light chain proteins cooperatively promote sarcomere growth in fast-twitch muscle

Myosin light chain proteins cooperatively promote ...

10

Structures of partially occupied hetero- tetramers provide insight into kainate receptor activation and desensitization

Structures of partially occupied hetero- tetramers...

8

Repurposing of microbial proteins as new-generation therapeutic agents for biomedical applications

Repurposing of microbial proteins as new-generatio...

24

Persistent and transient senescent cells contribute to brain-barrier development

Persistent and transient senescent cells contribut...

27

The circadian clock component BMAL1 enhances macrophage inflammation by nuclear translocation of peroxisomal β-oxidation enzyme MFP2

The circadian clock component BMAL1 enhances macro...

27

Infraslow histaminergic dynamics govern priming states to gate moment-to-moment memory accessibility

Infraslow histaminergic dynamics govern priming st...

23

Procollagen 1 assembles into phase-separated condensates in the endoplasmic reticulum

Procollagen 1 assembles into phase-separated conde...

22

Understanding and targeting erythroid cell metabolism

Understanding and targeting erythroid cell metabolism

27

Attenuated hypothalamic response to fructose via a dedicated gut-brain pathway

Attenuated hypothalamic response to fructose via a...

28

Molecular basis of target RNA cleavage by Cas13

Molecular basis of target RNA cleavage by Cas13

23

Monitoring in vivo transcription with synthetic serum markers

Monitoring in vivo transcription with synthetic se...

32

Single-cell mapping of regulatory DNA-protein interactions

Single-cell mapping of regulatory DNA-protein inte...

41

Cellular and subcellular heterogeneity of astrocytic Na+ homeostasis tuning astrocytes into functionally distinct subgroups in the mouse brain

Cellular and subcellular heterogeneity of astrocyt...

51

Quantification of disease-associated RNA tandem repeats by nanopore sensing

Quantification of disease-associated RNA tandem re...

63

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome

Expanding the targeted protein degradation approac...

92

RNA-triggered cell killing with CRISPR– Cas12a2

RNA-triggered cell killing with CRISPR– Cas12a2

98

Noninvasive methods to monitor dynamic single-cell events

Noninvasive methods to monitor dynamic single-cell...

92

Cell-type-targeted mitochondrial transplantation rescues cell degeneration

Cell-type-targeted mitochondrial transplantation r...

126

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

122

Whole-body molecular and cellular mapping of the laboratory mouse

Whole-body molecular and cellular mapping of the l...

124

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

Electrophysiological development and functional pl...

112

Tissue morphology predicts telomere shortening in human tissues

Tissue morphology predicts telomere shortening in ...

100

Breeding of Cotton

Breeding of Cotton

124

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

212

THALASSEMIA

THALASSEMIA

319

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

319

NMDA RECEPTORS

297

Neural Development

Neural Development

252

Transcription Factors

Transcription Factors

275

Interferons

196

RABIES

187

ANEMIA

174

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

194

Migraine

172

Dementia

213

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

128253

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1542

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1398

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

5251

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

471

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

447

HEAD AND NECK CANCER

HEAD AND NECK CANCER

524

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

320

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

449

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

484

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

432

Gestational diabetes therapeutics

Gestational diabetes therapeutics

468

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

474

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

689

Different types of Alzheimer's disease

Different types of Alzheimer's disease

566

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

490

Alzheimer’s therapeutics

Alzheimer’s therapeutics

561

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

515

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

522

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

463

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

467

APOE in Alzheimer’s

APOE in Alzheimer’s

615

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

609

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

689

Different types of Alzheimer's disease

Different types of Alzheimer's disease

566

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

490

Alzheimer’s therapeutics

Alzheimer’s therapeutics

561

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

515

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

522

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

463

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

467

APOE in Alzheimer’s

APOE in Alzheimer’s

615

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

609

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

468

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

555

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

423

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

432

Gestational diabetes therapeutics

Gestational diabetes therapeutics

468

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

474