Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

7549

Motivation and Pleasure in Psychosis?

Science Hangouts

Motivation and Pleasure in Psychosis?

33

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

Science Hangouts

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

37

Science News Highlights

Pyruvate kinase M2 dysregulation in Alzheimer’s disease

News highlights

Pyruvate kinase M2 dysregulation in Alzheimer’s disease

3

A glycoprotein linking diet, microbiota, and gut-liver dysfunction identified!

News highlights

A glycoprotein linking diet, microbiota, and gut-liver...

7

Electrophysiological studies in organoids using microelectrode array technology

News highlights

Electrophysiological studies in organoids using micro...

9

News

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

12

FGF21 helps cells cope with protein folding stress

FGF21 helps cells cope with protein folding stress

16

AI detects antibiotic candidates in prion proteins

AI detects antibiotic candidates in prion proteins

21

Coordination of rotating brain waves

Coordination of rotating brain waves

10

Nutrient in breast milk that shapes immune development

Nutrient in breast milk that shapes immune develop...

19

Antiviral molecules in bacteria

Antiviral molecules in bacteria

18

GLP-1s may alleviate depression through the microbiome

GLP-1s may alleviate depression through the microb...

27

Structural basis for RNA-based gene silencing

Structural basis for RNA-based gene silencing

26

Mitochondria tethered to the nuclear pore complex provides energy supply

Mitochondria tethered to the nuclear pore complex ...

52

Mechanism of immune evasion by Borrelia recurrentis

Mechanism of immune evasion by Borrelia recurrentis

25

Modulating glycine transporter to treat autism

Modulating glycine transporter to treat autism

82

AI adds speed and geometric precision to medical imaging

AI adds speed and geometric precision to medical i...

35

Parkinson's medication shows promise in treating depression

Parkinson's medication shows promise in treating d...

34

Coordination of rotating brain waves

Coordination of rotating brain waves

10

GLP-1s may alleviate depression through the microbiome

GLP-1s may alleviate depression through the microb...

27

Modulating glycine transporter to treat autism

Modulating glycine transporter to treat autism

82

Parkinson's medication shows promise in treating depression

Parkinson's medication shows promise in treating d...

34

Hyperglycosylation in Alzheimer’s disease

Hyperglycosylation in Alzheimer’s disease

28

Role of GRK2 in Alzheimer disease

Role of GRK2 in Alzheimer disease

54

Mitigating Huntington disease by targeting inflammatory pathway

Mitigating Huntington disease by targeting inflamm...

27

A neuronal receptor complex with distinctive properties

A neuronal receptor complex with distinctive prope...

43

Bain histamine neurons gate moment-to-moment memory access

Bain histamine neurons gate moment-to-moment memor...

35

Socioeconomic factors influence children’s brain structure and function

Socioeconomic factors influence children’s brain s...

44

A gut-brain pathway sends weaker fructose signal to the brain than glucose

A gut-brain pathway sends weaker fructose signal t...

49

Link between stress hormone and brain plasticity in early life

Link between stress hormone and brain plasticity i...

51

Brain circuit regulating the timing of torpor identified!

Brain circuit regulating the timing of torpor iden...

36

Telomeres and centromeres interact in some aggressive cancers

Telomeres and centromeres interact in some aggress...

41

Engineered Salmonella bacteria to treat solid tumors

Engineered Salmonella bacteria to treat solid tumors

35

Gene linking the trade-off between youth and longevity uncovered!

Gene linking the trade-off between youth and longe...

39

Blood test detects early signs of breast cancer recurrence

Blood test detects early signs of breast cancer re...

49

Nervous system helps lung cancer evade the immune system

Nervous system helps lung cancer evade the immune ...

38

How chemotherapy influences cancer inflammation

How chemotherapy influences cancer inflammation

57

DNA repair protein creates DNA damage similar to BRCA mutations

DNA repair protein creates DNA damage similar to B...

87

Selective degradation of proteins involved in pathological processes

Selective degradation of proteins involved in path...

82

Testosterone slows brain tumor growth

Testosterone slows brain tumor growth

83

How an enzyme affects infertility and cancer progression

How an enzyme affects infertility and cancer progr...

72

How gut bacteria toxin invades colon cells to trigger cancer

How gut bacteria toxin invades colon cells to trig...

76

New method reveals tumor environment that favor metastatic growth

New method reveals tumor environment that favor me...

104

Developing tumor microenvironment for cancer growth

Developing tumor microenvironment for cancer growth

84

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

71

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

102

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

105

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

92

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

108

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

119

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

132

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

117

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

120

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

142

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

158

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

248

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

166

AI detects antibiotic candidates in prion proteins

AI detects antibiotic candidates in prion proteins

21

AI adds speed and geometric precision to medical imaging

AI adds speed and geometric precision to medical i...

35

AI to evaluate changes in molecular condensates

AI to evaluate changes in molecular condensates

38

A blood signature for lung cancer risk

A blood signature for lung cancer risk

62

MouseMapper AI reveals hidden whole-body-damage caused by obesity

MouseMapper AI reveals hidden whole-body-damage ca...

71

AI to design miniproteins targeting GPCRs

AI to design miniproteins targeting GPCRs

103

AI tool to bridge gene regulation and cell fate decisions

AI tool to bridge gene regulation and cell fate de...

143

Genetics of blood proteins!

Genetics of blood proteins!

53

FaceAge AI tool predicts cancer patients survival

FaceAge AI tool predicts cancer patients survival

56

A potassium-gated ion channel identified!

A potassium-gated ion channel identified!

91

AI model for protein-protein interaction modeling

AI model for protein-protein interaction modeling

105

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

175

Gene signature predicting lung cancer recurrence

Gene signature predicting lung cancer recurrence

118

Protein-based data storage

Protein-based data storage

42

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

58

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

67

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

192

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

141

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

177

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

234

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

220

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

205

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

247

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

219

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

253

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

266

Reversing nerve damage in human corticospinal organoid-slice connectoid model

Reversing nerve damage in human corticospinal orga...

39

Zinc finger proteins act on gene promoters to control differentiation of stem cells

Zinc finger proteins act on gene promoters to cont...

52

Identifying the ‘organizer’ cells that build bone marrow

Identifying the ‘organizer’ cells that build bone ...

62

Not all Alzheimer’s leads to dementia

Not all Alzheimer’s leads to dementia

85

What keeps vision cells alive?

What keeps vision cells alive?

162

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

90

A long-term and scalable system to record from neural organoids

A long-term and scalable system to record from neu...

94

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

130

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

145

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

152

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

283

How cell walls guide stem cells

How cell walls guide stem cells

190

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

174

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

36

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

41

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

72

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

95

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

90

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

118

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

133

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

116

How longevity is inherited across generations

How longevity is inherited across generations

185

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

136

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

172

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

143

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

129

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

12

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

27

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

126

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

157

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

164

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

196

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

489

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

499

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

484

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

561

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

386

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

452

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

590

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

45

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

37

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

36

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

62

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

57

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

86

Mechanisms of aortic aneurysm progression

Mechanisms of aortic aneurysm progression

59

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

157

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

120

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

139

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

129

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

137

A novel inflammatory function of platelets

A novel inflammatory function of platelets

149

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

60

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

91

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

120

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

117

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

152

sncRNAs in sperm aging

sncRNAs in sperm aging

180

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

180

How reproductive organs form

How reproductive organs form

216

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

172

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

177

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

215

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

253

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

214

FGF21 helps cells cope with protein folding stress

FGF21 helps cells cope with protein folding stress

16

Structural basis for RNA-based gene silencing

Structural basis for RNA-based gene silencing

26

Mitochondria tethered to the nuclear pore complex provides energy supply

Mitochondria tethered to the nuclear pore complex ...

52

RNA’s hidden role as protein chaperone

RNA’s hidden role as protein chaperone

138

Collagen forms condensate inside cells

Collagen forms condensate inside cells

55

A targeted RNA cleavage and repair method, to fix dysfunctional RNA

A targeted RNA cleavage and repair method, to fix ...

38

Role of condensates in signaling

Role of condensates in signaling

70

How acid removes water from proteins

How acid removes water from proteins

51

How the protein interact to send the inflammatory signals

How the protein interact to send the inflammatory ...

75

How cells restart protein synthesis after awakening from dormant stste

How cells restart protein synthesis after awakenin...

52

Friedreich’s ataxia reveals how DNA folding can silence a key gene

Friedreich’s ataxia reveals how DNA folding can si...

43

Mechanism of protein polymerization in the cells

Mechanism of protein polymerization in the cells

45

New proteins revealed in dark proteome

New proteins revealed in dark proteome

69

Antiviral molecules in bacteria

Antiviral molecules in bacteria

18

Mechanism of immune evasion by Borrelia recurrentis

Mechanism of immune evasion by Borrelia recurrentis

25

A new natural depsipeptide antibiotic discovered!

A new natural depsipeptide antibiotic discovered!

15

How cells fight infection from the inside

How cells fight infection from the inside

41

Gut microbe found to worsen sepsis

Gut microbe found to worsen sepsis

35

A link between autoantibodies and neurological symptoms in long COVID

A link between autoantibodies and neurological sym...

34

Microbiome restructuring associated with medical exposure

Microbiome restructuring associated with medical e...

38

HIV-1 remodels nuclear pores to infect immune cells

HIV-1 remodels nuclear pores to infect immune cells

72

Myocarditis after mRNA vaccination is attributed to mitochondrial stress

Myocarditis after mRNA vaccination is attributed t...

61

Engineered bacteria to treat liver-related brain dysfunction

Engineered bacteria to treat liver-related brain d...

74

How pathogens switch on their virulence

How pathogens switch on their virulence

60

Disease-causing pathogen rewires gut metabolism to grow

Disease-causing pathogen rewires gut metabolism to...

63

Pro- and anti-HIV host factors in T cells

Pro- and anti-HIV host factors in T cells

69

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

55

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

42

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

46

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

76

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

57

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

60

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

78

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

82

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

88

A developmental atlas for genes and cells

A developmental atlas for genes and cells

129

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

153

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

126

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

226

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

28

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

34

Cure for dry eye disease

Cure for dry eye disease

57

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

57

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

98

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

75

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

78

Nicotine Biosynthesis!

Nicotine Biosynthesis!

144

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

110

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

178

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

101

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

111

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

177

Nutrient in breast milk that shapes immune development

Nutrient in breast milk that shapes immune develop...

19

Body clock found to control inflammatory responses in macrophages

Body clock found to control inflammatory responses...

55

How the body remembers the tumor?

How the body remembers the tumor?

78

Molecular mechanisms to maintain intestinal barrier function

Molecular mechanisms to maintain intestinal barrie...

68

Reversing chromatin aging with SIRT6 overexpression

Reversing chromatin aging with SIRT6 overexpression

120

Molecule linked to treatment-resistant inflammatory bowel disease identified!

Molecule linked to treatment-resistant inflammator...

54

A key protein in the inflammatory response to infections identified

A key protein in the inflammatory response to infe...

61

Proper protein recycling helps exhausted immune cells fight tumors

Proper protein recycling helps exhausted immune ce...

66

How immune cell networks drive liver disease

How immune cell networks drive liver disease

75

NO-independent inflammatory response by iNOS

NO-independent inflammatory response by iNOS

73

Stromal-immune cell circuit in human lymph nodes

Stromal-immune cell circuit in human lymph nodes

95

Mitochondria keep immune cells “ready to respond”

Mitochondria keep immune cells “ready to respond”

90

How the immune system rewrites rapid aging

How the immune system rewrites rapid aging

90

Temperature behaves differently in the cell

Temperature behaves differently in the cell

35

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

43

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

78

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

85

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

176

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

458

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

358

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

817

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

446

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

426

Printed skin to replace animal testing

Printed skin to replace animal testing

425

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

410

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

430

Gene transcription measurement in the living brain

Gene transcription measurement in the living brain

48

How the brain takes out its trash

How the brain takes out its trash

58

Single-cell method for mapping DNA-protein interactions

Single-cell method for mapping DNA-protein interac...

76

Ultrasound to alter how the brain responds to pain

Ultrasound to alter how the brain responds to pain

57

Surprising cellular dynamics of the aging brain

Surprising cellular dynamics of the aging brain

105

New CRISPR tool eliminates undesired cells

New CRISPR tool eliminates undesired cells

80

Multiplexed MRI provides a comprehensive view of the human brain

Multiplexed MRI provides a comprehensive view of t...

76

“Aging clocks” to measure body decline

“Aging clocks” to measure body decline

62

“MitoCatch” delivers healthy mitochondria to diseased cells

“MitoCatch” delivers healthy mitochondria to disea...

126

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

89

How the body senses cold

How the body senses cold

171

New computational biology for genome sequencing analysis

New computational biology for genome sequencing an...

129

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

135

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

194

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

386

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

387

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

386

How the brain regulates emotions

How the brain regulates emotions

539

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

458

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

441

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

491

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

459

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

459

Link between dietary choices and brain health

Link between dietary choices and brain health

438

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

406

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

522

Research

FGF21 reduces ER stress by enhancing the unfolded protein and integrated stress responses through increased sulfide signaling

FGF21 reduces ER stress by enhancing the unfolded ...

14

Deep learning reveals antimicrobial peptides within prions

Deep learning reveals antimicrobial peptides withi...

10

Pyruvate kinase M2 in Alzheimer’s disease: from dysregulation to therapeutic inhibition

Pyruvate kinase M2 in Alzheimer’s disease: from dy...

586

Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH

Angptl4 integrates dietary and microbial signals t...

17

Microelectrode array technology for organoids and microphysiological systems

Microelectrode array technology for organoids and ...

23

DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity

DNA-intercalating antiphage molecules trigger abor...

12

Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog

Microbiota-driven gut-brain signaling underlies an...

18

Targeting the NLRP3 Inflammasome in Atherosclerosis: A Review of Natural Products and Their Molecular Mechanisms

Targeting the NLRP3 Inflammasome in Atherosclerosi...

31

Macrophage-mediated refinement of the dural lymphatic regulates social behavior

Macrophage-mediated refinement of the dural lympha...

26

Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis

Complement inhibition by a unique cluster of immun...

28

Glycine-modulating Slc6a20a-ASO restores NMDA receptor function in SHANK2 and SHANK3-mutant mice and cortical organoids

Glycine-modulating Slc6a20a-ASO restores NMDA rece...

59

Adaptive Riemannian optimization for multi- scale diffeomorphic matching

Adaptive Riemannian optimization for multi- scale ...

24

Replication origin flexibility: a tool to mitigate the hazards of excess replication

Replication origin flexibility: a tool to mitigate...

29

FGF21 reduces ER stress by enhancing the unfolded protein and integrated stress responses through increased sulfide signaling

FGF21 reduces ER stress by enhancing the unfolded ...

14

Deep learning reveals antimicrobial peptides within prions

Deep learning reveals antimicrobial peptides withi...

10

Pyruvate kinase M2 in Alzheimer’s disease: from dysregulation to therapeutic inhibition

Pyruvate kinase M2 in Alzheimer’s disease: from dy...

586

Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH

Angptl4 integrates dietary and microbial signals t...

17

DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity

DNA-intercalating antiphage molecules trigger abor...

12

Microbiota-driven gut-brain signaling underlies antidepressant effects of a GLP-1 analog

Microbiota-driven gut-brain signaling underlies an...

18

Targeting the NLRP3 Inflammasome in Atherosclerosis: A Review of Natural Products and Their Molecular Mechanisms

Targeting the NLRP3 Inflammasome in Atherosclerosi...

31

Macrophage-mediated refinement of the dural lymphatic regulates social behavior

Macrophage-mediated refinement of the dural lympha...

26

Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis

Complement inhibition by a unique cluster of immun...

28

Glycine-modulating Slc6a20a-ASO restores NMDA receptor function in SHANK2 and SHANK3-mutant mice and cortical organoids

Glycine-modulating Slc6a20a-ASO restores NMDA rece...

59

Dissecting histological transformation

Dissecting histological transformation

40

Efficacy and target engagement of dopamine agonist pramipexole for anhedonic depression: a randomized placebo-controlled trial

Efficacy and target engagement of dopamine agonist...

23

Timescapes of non-human experience

Timescapes of non-human experience

21

Microelectrode array technology for organoids and microphysiological systems

Microelectrode array technology for organoids and ...

23

Adaptive Riemannian optimization for multi- scale diffeomorphic matching

Adaptive Riemannian optimization for multi- scale ...

24

Replication origin flexibility: a tool to mitigate the hazards of excess replication

Replication origin flexibility: a tool to mitigate...

29

Molecular basis of target RNA cleavage by Cas13

Molecular basis of target RNA cleavage by Cas13

36

Monitoring in vivo transcription with synthetic serum markers

Monitoring in vivo transcription with synthetic se...

44

Single-cell mapping of regulatory DNA-protein interactions

Single-cell mapping of regulatory DNA-protein inte...

44

Cellular and subcellular heterogeneity of astrocytic Na+ homeostasis tuning astrocytes into functionally distinct subgroups in the mouse brain

Cellular and subcellular heterogeneity of astrocyt...

53

Quantification of disease-associated RNA tandem repeats by nanopore sensing

Quantification of disease-associated RNA tandem re...

66

Expanding the targeted protein degradation approach with small molecule chimeras directed to the 26S proteasome

Expanding the targeted protein degradation approac...

93

RNA-triggered cell killing with CRISPR– Cas12a2

RNA-triggered cell killing with CRISPR– Cas12a2

99

Noninvasive methods to monitor dynamic single-cell events

Noninvasive methods to monitor dynamic single-cell...

95

Cell-type-targeted mitochondrial transplantation rescues cell degeneration

Cell-type-targeted mitochondrial transplantation r...

129

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

126

Breeding of Cotton

Breeding of Cotton

132

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

225

THALASSEMIA

THALASSEMIA

333

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

331

NMDA RECEPTORS

305

Neural Development

Neural Development

260

Transcription Factors

Transcription Factors

285

Interferons

201

RABIES

196

ANEMIA

181

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

201

Migraine

178

Dementia

220

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

130228

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1555

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1403

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

5325

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

474

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

448

HEAD AND NECK CANCER

HEAD AND NECK CANCER

531

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

323

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

450

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

485

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

433

Gestational diabetes therapeutics

Gestational diabetes therapeutics

477

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

477

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

695

Different types of Alzheimer's disease

Different types of Alzheimer's disease

567

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

493

Alzheimer’s therapeutics

Alzheimer’s therapeutics

572

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

525

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

525

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

465

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

470

APOE in Alzheimer’s

APOE in Alzheimer’s

624

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

612

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

695

Different types of Alzheimer's disease

Different types of Alzheimer's disease

567

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

493

Alzheimer’s therapeutics

Alzheimer’s therapeutics

572

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

525

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

525

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

465

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

470

APOE in Alzheimer’s

APOE in Alzheimer’s

624

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

612

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

469

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

565

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

424

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

433

Gestational diabetes therapeutics

Gestational diabetes therapeutics

477

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

477