Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

15715

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

Science Hangouts

Primate Brain Expansion: Nature’s social experiments with gene, cell and anatomical novelty

60

Systems Biology & Medicine: Markers, Mechanisms and Pathways

Science Hangouts

Systems Biology & Medicine: Markers, Mechanisms and Pathways

73

Science News Highlights

Protein regulation by carbamate post-translational modifications

News highlights

Protein regulation by carbamate post-translational modifications

16

Understanding glycan function

News highlights

Understanding glycan function

17

How phage-encoded transcription and sigma factors reprogram host cells

News highlights

How phage-encoded transcription and sigma factors repr...

17

News

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

5

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

8

Changes in retinal dopamine balance during inherited retinal degenerations

Changes in retinal dopamine balance during inherit...

21

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

99

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

40

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

930

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

172

Genes that help flatworms regenerate their brains identified!

Genes that help flatworms regenerate their brains...

27

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

23

New role for cohesin in DNA replication

New role for cohesin in DNA replication

75

Linking brain injury to brain tumors

Linking brain injury to brain tumors

49

Why do we stay afraid for so long when the brain’s first alarm fires so fast?

Why do we stay afraid for so long when the brain’s...

38

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

75

Cocaine hijacks a brain circuit that naturally supports flexible behavior

Cocaine hijacks a brain circuit that naturally sup...

5

Changes in retinal dopamine balance during inherited retinal degenerations

Changes in retinal dopamine balance during inherit...

21

Genes that help flatworms regenerate their brains identified!

Genes that help flatworms regenerate their brains...

27

Linking brain injury to brain tumors

Linking brain injury to brain tumors

49

Why do we stay afraid for so long when the brain’s first alarm fires so fast?

Why do we stay afraid for so long when the brain’s...

38

Molecular mechanism of short-term synaptic plasticity was discovered

Molecular mechanism of short-term synaptic plastic...

45

A hidden brain region coordinates metabolic adaptations to cold

A hidden brain region coordinates metabolic adapta...

59

Retinotopic remapping of the visual system in deaf adults

Retinotopic remapping of the visual system in deaf...

42

How Alzheimer’s risk factor, APOE4, damages blood vessels?

How Alzheimer’s risk factor, APOE4, damages blood ...

102

Neuroprosthesis for paralysis enables simultaneous speech and body language

Neuroprosthesis for paralysis enables simultaneous...

210

Brain activity can predict a risky decision before it’s made

Brain activity can predict a risky decision before...

88

Why some Huntington disease patients decline years earlier

Why some Huntington disease patients decline years...

75

Mitochondrial transfer from bone marrow transplant in mitochondrial disease

Mitochondrial transfer from bone marrow transplant...

128

Sex specific influence of dietary supplement on lung tumor growth

Sex specific influence of dietary supplement on lu...

75

Ameliorating fibrosis in cancer via senescence-directed nanotherapy

Ameliorating fibrosis in cancer via senescence-dir...

81

A cellular pathway that allows colorectal cancer to metastasize identified!

A cellular pathway that allows colorectal cancer t...

104

Cancer-linked protein binds to chromosome in unexpected way

Cancer-linked protein binds to chromosome in unexp...

71

Loss of Y chromosome in men could be early warning sign of cancer

Loss of Y chromosome in men could be early warning...

53

Anti-seizure drug fights aggressive childhood brain tumors

Anti-seizure drug fights aggressive childhood brai...

75

Reprogramming immune cells to boost glioblastoma chemotherapy

Reprogramming immune cells to boost glioblastoma c...

83

Pancreatic cancer uses blood-clotting system to evade immune attack

Pancreatic cancer uses blood-clotting system to ev...

65

Childhood chemotherapy leaves a lasting mutational footprint in healthy tissues

Childhood chemotherapy leaves a lasting mutational...

80

Region-specific brain tumors from gene mutations

Region-specific brain tumors from gene mutations

99

Molecular mechanism that helps aggressive colorectal cancer to spread

Molecular mechanism that helps aggressive colorect...

100

Tumor-liver interplay in cancer progression

Tumor-liver interplay in cancer progression

118

A tumor-liver interplay in colorectal cancer cachexia

A tumor-liver interplay in colorectal cancer cachexia

111

Drug increases energy expenditure without activating brown fat

Drug increases energy expenditure without activati...

40

How obesity enhances breast cancer risk?

How obesity enhances breast cancer risk?

70

Mechanism of obesity relapse

Mechanism of obesity relapse

177

Stress hormone timing creates a different kind of obesity

Stress hormone timing creates a different kind of ...

136

Ketogenic diet boosts liver health in addition to weight loss

Ketogenic diet boosts liver health in addition to ...

116

Short bursts of physical activity promote metabolic health better than moderate-intensity exercise

Short bursts of physical activity promote metaboli...

520

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

183

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

210

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

252

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

286

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

271

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

245

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

280

A foundational model redirects cell fate with just a single stimulus

A foundational model redirects cell fate with just...

99

Unmasking “zombie cells” in aging tissue with an AI-powered barcode

Unmasking “zombie cells” in aging tissue with an A...

172

Scientific manuscripts-turned into AI agents

Scientific manuscripts-turned into AI agents

159

AI reveals sex-specific patterns on retinal age

AI reveals sex-specific patterns on retinal age

60

New AI technique making surgeries safer and more precise

New AI technique making surgeries safer and more p...

63

First microprotein atlas of human frontal cortex in Alzheimer’s disease

First microprotein atlas of human frontal cortex i...

102

AI language models for aging biology

AI language models for aging biology

191

A generalist AI tool for abdominal CT diagnosis

A generalist AI tool for abdominal CT diagnosis

94

4D AI models predict how mitochondria respond to drug treatment

4D AI models predict how mitochondria respond to d...

128

A new genomic language model to spot genetic variants

A new genomic language model to spot genetic variants

154

Mapping the protein universe by uniting sequence and structure

Mapping the protein universe by uniting sequence a...

117

Proteomic signatures in children blood may provide clues to cardiometabolic diseases later in life

Proteomic signatures in children blood may provide...

82

AI finds hidden human proteins and their function

AI finds hidden human proteins and their function

234

Nanoparticles target autophagy to sensitize gliomas to radiotherapy

Nanoparticles target autophagy to sensitize glioma...

23

Protein-based data storage

Protein-based data storage

221

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

213

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

224

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

368

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

287

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

332

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

389

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

377

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

345

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

385

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

345

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

420

Replacing mouse cortex with human organoids!

Replacing mouse cortex with human organoids!

84

Tendon and ligament stem cells identified!

Tendon and ligament stem cells identified!

114

AI identifies regulatory hub for aging in hematopoietic stem cells

AI identifies regulatory hub for aging in hematopo...

109

Abnormal differentiation of fetal neural progenitor cells causes autistic-like behavior

Abnormal differentiation of fetal neural progenito...

84

Microglial cells from patients with genetic and sporadic frontotemporal dementia differ from each other

Microglial cells from patients with genetic and sp...

124

Brain organoids survive and mature for over 5 years

Brain organoids survive and mature for over 5 years

103

A new organoid model of the cerebral cortex

A new organoid model of the cerebral cortex

125

Human heart valve-like tissues from pluripotent stem cells

Human heart valve-like tissues from pluripotent st...

121

A novel 3D brain tissue model

A novel 3D brain tissue model

152

EV secretome to treat cardiac fibrosis

EV secretome to treat cardiac fibrosis

136

Preventing excessive stem cell proliferation via cell junction proteins

Preventing excessive stem cell proliferation via c...

125

Protein excess tips the balance of cellular health

Protein excess tips the balance of cellular health

207

Reverting aged cells to stem cells

Reverting aged cells to stem cells

274

Enhancer–gene regulatory interactions mapping from single-cell data

Enhancer–gene regulatory interactions mapping from...

70

New genetic mechanism essential for hearing identified!

New genetic mechanism essential for hearing identi...

68

The genetic code behind psoriasis cracked

The genetic code behind psoriasis cracked

65

Rare inherited EGFR mutation linked to increased lung cancer risk

Rare inherited EGFR mutation linked to increased l...

76

Eight genetic ‘fingerprints’ for aggressive prostate cancer

Eight genetic ‘fingerprints’ for aggressive prosta...

58

Feeding mice fewer calories reduce DNA mutations

Feeding mice fewer calories reduce DNA mutations

73

Generational chromosome repair!

Generational chromosome repair!

70

Gene defects linked to primary ciliary dyskinesia

Gene defects linked to primary ciliary dyskinesia

70

Is our personality written in our genes?

Is our personality written in our genes?

172

Gene expression and metabolomics in aging women

Gene expression and metabolomics in aging women

93

How chromosomes find their partners

How chromosomes find their partners

163

New gene activation tool!

New gene activation tool!

119

Role of Vitamin B12 in spliceosomopathy

Role of Vitamin B12 in spliceosomopathy

136

Why high levels of the amino acid cysteine are toxic to cells

Why high levels of the amino acid cysteine are tox...

75

Healthy eating linked to slower biological aging

Healthy eating linked to slower biological aging

60

A bile acid shows potential for reducing liver fat

A bile acid shows potential for reducing liver fat

70

Blocking a protein may reduce buildup of harmful aging cells

Blocking a protein may reduce buildup of harmful a...

102

Gut cell turnover is determined by nutrient quantity and not quality!

Gut cell turnover is determined by nutrient quanti...

141

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

174

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

177

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

165

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

170

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

270

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

293

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

287

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

309

Gut-heart connection in heart failure!

Gut-heart connection in heart failure!

51

An atypical GPCR signaling pathway that drives heart scarring

An atypical GPCR signaling pathway that drives hea...

66

Atherosclerosis is an autoimmune disease!

Atherosclerosis is an autoimmune disease!

56

Mechanism behind dangerous blood-clotting disorder uncovered!

Mechanism behind dangerous blood-clotting disorder...

76

Stressed mitochondria protect the heart!

Stressed mitochondria protect the heart!

105

Mechanism of diabetic drug mediated heart failure protection

Mechanism of diabetic drug mediated heart failure ...

103

Capillaries and not arteries give rise to backup blood vessels

Capillaries and not arteries give rise to backup ...

99

Hypothalamus-heart-tumor axis in environmental eustress protection against cardiotoxicity and tumor growth

Hypothalamus-heart-tumor axis in environmental eus...

129

Coordinating the development of heart muscle and vasculature

Coordinating the development of heart muscle and v...

117

Breaking down barriers to cardiac regeneration

Breaking down barriers to cardiac regeneration

127

Low heart disease–linked transcription factor dismantles DNA organization

Low heart disease–linked transcription factor dism...

150

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

147

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

194

Menopause leaves a fingerprint that may predict dementia risk

Menopause leaves a fingerprint that may predict de...

135

Brain circuit linked to food cravings during pregnancy identified!

Brain circuit linked to food cravings during pregn...

160

Alpha-1 antitrypsin emerges as a potential target for preventing spontaneous preterm birth

Alpha-1 antitrypsin emerges as a potential target ...

70

Postbiotics may boost female fertility

Postbiotics may boost female fertility

136

X chromosome inactivation in immune cells

X chromosome inactivation in immune cells

146

Brain development risks associated with certain medications during pregnancy

Brain development risks associated with certain me...

147

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

218

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

218

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

254

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

240

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

304

sncRNAs in sperm aging

sncRNAs in sperm aging

355

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

287

New role for cohesin in DNA replication

New role for cohesin in DNA replication

75

Mechanisms of protein production, transport, and folding in bacterial cells

Mechanisms of protein production, transport, and f...

48

How calcium channels in muscle cells open together

How calcium channels in muscle cells open together

93

A new mechanism for reading extra-long genes in neurons

A new mechanism for reading extra-long genes in ne...

50

How taste receptors tickle taste buds?

How taste receptors tickle taste buds?

66

How a protein shapes the cell membrane

How a protein shapes the cell membrane

70

Structural basis of metabotropic glutamate receptor coupling with beta-arrestins

Structural basis of metabotropic glutamate recept...

86

Alternative pathway for transthyretin denaturation!

Alternative pathway for transthyretin denaturation!

57

How blood cells release key signaling lipid

How blood cells release key signaling lipid

71

Transcription of eight letter codon!

Transcription of eight letter codon!

84

How bacteria assemble outer membrane proteins

How bacteria assemble outer membrane proteins

86

Regulation of protein transport from ER to Golgi

Regulation of protein transport from ER to Golgi

73

Why some misfolded proteins do not undergo proteasomal degradation

Why some misfolded proteins do not undergo protea...

75

Gut microbiome development may help predict type 1 diabetes in children at high risk

Gut microbiome development may help predict type 1...

930

How Epstein-Barr Virus triggers multiple sclerosis relapse

How Epstein-Barr Virus triggers multiple sclerosi...

113

How bacteria pump an antibiotic out of their cells

How bacteria pump an antibiotic out of their cells

68

Highly potent compound that blocks Ebola virus entry discovered!

Highly potent compound that blocks Ebola virus ent...

67

Despite antibiotic treatment why strep throat can linger?

Despite antibiotic treatment why strep throat can ...

112

Hidden weak spot in how bacteria build the tails

Hidden weak spot in how bacteria build the tails

53

Lung fibrosis from a bacterial protein fragment

Lung fibrosis from a bacterial protein fragment

68

A gut bacterium and its metabolite found to delay aging

A gut bacterium and its metabolite found to delay ...

119

Urinary microbiome can make androgens!

Urinary microbiome can make androgens!

100

Methylation puts parasites in motion

Methylation puts parasites in motion

78

A skin fungus hides in hair follicles!

A skin fungus hides in hair follicles!

180

New antibiotic mechanisms discovered!

New antibiotic mechanisms discovered!

219

Antibiotic-tolerant bacteria rely on a hidden survival strategy

Antibiotic-tolerant bacteria rely on a hidden surv...

142

Limits of “precise” gene editing in human embryos

Limits of “precise” gene editing in human embryos

128

Regulatory logic of neuronal differentiation

Regulatory logic of neuronal differentiation

67

Signaling pathway controlling brain development timing identified!

Signaling pathway controlling brain development ti...

74

Role of glycolysis and pentose phosphate pathway in the development of human cortex

Role of glycolysis and pentose phosphate pathway i...

78

4D map of the hair follicle organogenesis

4D map of the hair follicle organogenesis

79

How folic acid protects the developing brain and spinal cord

How folic acid protects the developing brain and s...

85

A lipid regulator of Sonic hedgehog signaling influences heart and lung development

A lipid regulator of Sonic hedgehog signaling infl...

119

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

167

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

175

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

163

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

154

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

187

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

165

Why do spruce take decades to reproduce?

Why do spruce take decades to reproduce?

63

A molecular bridge connects two small GTPase pathways in plants

A molecular bridge connects two small GTPase pathw...

52

New gene-editing tool for hard-to-breed perennial crops

New gene-editing tool for hard-to-breed perennial ...

94

Increasing plants synthesis of lignin and starch

Increasing plants synthesis of lignin and starch

91

A fungal protein that causes leaf loss in crops discovered

A fungal protein that causes leaf loss in crops di...

102

Phytochemicals, microbiome and health benefits

Phytochemicals, microbiome and health benefits

172

Programmable design of synthetic plant immune receptors

Programmable design of synthetic plant immune rece...

149

‘Saprotropism’ helps roots avoid decaying plant matter

‘Saprotropism’ helps roots avoid decaying plant ma...

160

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

150

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

152

Cure for dry eye disease

Cure for dry eye disease

188

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

205

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

209

How repeated exposures may make allergies worse

How repeated exposures may make allergies worse

8

Why some people can fight infections better than others?

Why some people can fight infections better than o...

112

Restoring aging T cell function to fight cancer

Restoring aging T cell function to fight cancer

100

Gene circuits of human immunity

Gene circuits of human immunity

118

Cell proliferation protein promotes inflammation in aging cells

Cell proliferation protein promotes inflammation i...

107

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

A necroptotic-to-apoptotic signaling axis underlie...

119

Cellular stress sensor also acts as a cholesterol sensor in immune cells

Cellular stress sensor also acts as a cholesterol ...

85

Brain-to-liver pathway that protects against liver inflammation

Brain-to-liver pathway that protects against liver...

108

Transition from milk to solid food shapes immune system development

Transition from milk to solid food shapes immune s...

106

Malaria causes permanent damage to phagocytes in the spleen

Malaria causes permanent damage to phagocytes in t...

101

A critical immune pathway in systemic anaphylactic responses identified!

A critical immune pathway in systemic anaphylactic...

111

Blocking xenophagocytosis for interspecies organ generation

Blocking xenophagocytosis for interspecies organ g...

105

How autophagy helps to reduce inflammation

How autophagy helps to reduce inflammation

134

Microbially produced adhesive materials from glucose instead of petroleum

Microbially produced adhesive materials from gluco...

56

New modular hydrogel plug-and-play platform

New modular hydrogel plug-and-play platform

109

Air-permeable hydrogels!

Air-permeable hydrogels!

155

Temperature behaves differently in the cell

Temperature behaves differently in the cell

154

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

136

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

182

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

209

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

280

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

559

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

453

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

941

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

551

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

537

A world-first DNA computer

A world-first DNA computer

39

Self-assembly of a virus-like particle

Self-assembly of a virus-like particle

65

New genomic editing method for correcting multiple mutations at once

New genomic editing method for correcting multiple...

57

Combined ultra- MRI with brain maps links cortical perfusion, microstructure, and metabolism

Combined ultra- MRI with brain maps links cortical...

87

Rewiring ribosomes to specialize in one protein

Rewiring ribosomes to specialize in one protein

60

A Google-like search engine for single-cell RNA

A Google-like search engine for single-cell RNA

98

New CRISPR method to control protein production in cells

New CRISPR method to control protein production in...

101

Electronic skin for prosthetics to sense temperature and pressure

Electronic skin for prosthetics to sense temperatu...

78

Computer framework identifies disease driving genes in asthma

Computer framework identifies disease driving gene...

95

Viral RNA elements functional map!

Viral RNA elements functional map!

88

How proteins change shape and move

How proteins change shape and move

97

Cellular factors controlling nonviral genome editing efficiency identified!

Cellular factors controlling nonviral genome editi...

101

Next-gen patient-derived cancer models

Next-gen patient-derived cancer models

153

How a mouse survives in one of Earth’s harshest environments

How a mouse survives in one of Earth’s harshest en...

168

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

310

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

499

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

525

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

483

How the brain regulates emotions

How the brain regulates emotions

711

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

570

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

574

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

585

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

556

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

551

Link between dietary choices and brain health

Link between dietary choices and brain health

521

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

513

Research

Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity

Sensory neuronal mTORC1 kinase signaling establish...

10

Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa

Altered Retinal Dopamine Homeostasis in Murine Mod...

21

Carbamate post-translational modifications: bridging CO2 biology and protein regulation

Carbamate post-translational modifications: bridgi...

23

Intracellular Pseudomonas aeruginosa: internalization and survival

Intracellular Pseudomonas aeruginosa: internalizat...

20

You can’t see what you don’t look for: why glycan function remains in the dark

You can’t see what you don’t look for: why glycan ...

918

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools

Beyond AMGs: Phage-encoded transcription and sigma...

20

Beta2-adrenergic stimulation by fenoterol increases energy expenditure without activating human brown adipose tissue

Beta2-adrenergic stimulation by fenoterol increase...

22

Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk

Gut microbiome maturation in early childhood inter...

23

RamanOmics decodes the spatial vibrational–molecular architecture of senescence in aging and repair

RamanOmics decodes the spatial vibrational–molecul...

672

Combinatorial mechanisms specify cellular location and neurotransmitter identity during planarian neurogenesis

Combinatorial mechanisms specify cellular location...

18

Autophagy inhibition sensitizes radiotherapy responses in high-grade mutant IDH1 glioma

Autophagy inhibition sensitizes radiotherapy respo...

15

Cohesin reshapes replication fork contacts to aid fork slowing and reversal

Cohesin reshapes replication fork contacts to aid ...

32

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

527

Sensory neuronal mTORC1 kinase signaling establishes neuroimmune memory that initiates allergic immunity

Sensory neuronal mTORC1 kinase signaling establish...

10

Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa

Altered Retinal Dopamine Homeostasis in Murine Mod...

21

Carbamate post-translational modifications: bridging CO2 biology and protein regulation

Carbamate post-translational modifications: bridgi...

23

Intracellular Pseudomonas aeruginosa: internalization and survival

Intracellular Pseudomonas aeruginosa: internalizat...

20

You can’t see what you don’t look for: why glycan function remains in the dark

You can’t see what you don’t look for: why glycan ...

918

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools

Beyond AMGs: Phage-encoded transcription and sigma...

20

Beta2-adrenergic stimulation by fenoterol increases energy expenditure without activating human brown adipose tissue

Beta2-adrenergic stimulation by fenoterol increase...

22

Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk

Gut microbiome maturation in early childhood inter...

23

RamanOmics decodes the spatial vibrational–molecular architecture of senescence in aging and repair

RamanOmics decodes the spatial vibrational–molecul...

672

Combinatorial mechanisms specify cellular location and neurotransmitter identity during planarian neurogenesis

Combinatorial mechanisms specify cellular location...

18

Autophagy inhibition sensitizes radiotherapy responses in high-grade mutant IDH1 glioma

Autophagy inhibition sensitizes radiotherapy respo...

15

Cohesin reshapes replication fork contacts to aid fork slowing and reversal

Cohesin reshapes replication fork contacts to aid ...

32

Beyond breathing: multimodal pathways connecting olfaction to autonomic nervous system modulation

Beyond breathing: multimodal pathways connecting o...

28

A thermodynamically favoured molecular computer

A thermodynamically favoured molecular computer

45

Targeted genomic integration and rearrangement using prime assembly

Targeted genomic integration and rearrangement usi...

96

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Assessing molecular, cellular and transcriptomic b...

177

High-throughput, amplification-free detection of endogenous gene expression perturbations via fluorescence anisotropy

High-throughput, amplification-free detection of e...

87

Norway spruce spatiotemporal programs of conifer reproductive development

Norway spruce spatiotemporal programs of conifer r...

75

An open benchmark and language models for AI in aging biology

An open benchmark and language models for AI in ag...

62

Synonymous sequence design controls the folding, processing, and activity of the therapeutic protein ADAMTS13

Synonymous sequence design controls the folding, p...

58

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data

Whole-cell particle-based digital twin simulations...

58

4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning

4D spatiotemporal landscape of mitochondrial pheno...

55

Boosting genome editing in perennial plants by CRISPR-Combo mediated morphogenic gene activation

Boosting genome editing in perennial plants by CRI...

88

CRISPR genome editing in plants without tissue culture

CRISPR genome editing in plants without tissue cul...

183

Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission

Towards a proteomic plasma biomarker panel for dia...

288

Automated prototyping of genetic codes

Automated prototyping of genetic codes

289

Breeding of Cotton

Breeding of Cotton

703

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

916

THALASSEMIA

THALASSEMIA

1036

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

1031

NMDA RECEPTORS

482

Neural Development

Neural Development

468

Transcription Factors

Transcription Factors

457

Interferons

409

RABIES

420

ANEMIA

419

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

406

Migraine

337

Dementia

427

Improving Detection of Variant MECOM Rearrangements Through Optical Genome Mapping and Repurposed Targeted RNA-Seq

Improving Detection of Variant MECOM Rearrangement...

527

Prevalence of Cancer Predisposition Variants in a Pediatric Pineoblastoma Cohort

Prevalence of Cancer Predisposition Variants in a ...

27

Comprehensive Pan-Cancer Assessment of the APC I1307K Variant Reveals Ancestry-Independent Colorectal Cancer Risk

Comprehensive Pan-Cancer Assessment of the APC I13...

35

Prevalence and Tumor Characteristics of Patients with TMEM127 Pathogenic Variants in a Large, Pan-Cancer Cohort

Prevalence and Tumor Characteristics of Patients w...

2933

Evaluating the Role of Mitochondrial Dysfunction in Muscle Cell Differentiation in an iPSC-derived Skeletal Muscle Model of Barth Syndrome

Evaluating the Role of Mitochondrial Dysfunction i...

100

Sepiapterin Responsiveness Over 14 Days in Children and Adults with Phenylketonuria: Pooled Results from Three Phase 3 Clinical Trials

Sepiapterin Responsiveness Over 14 Days in Childre...

98

Re-evaluation of Genotype-Phenotype Correlations in D-Bifunctional Protein Deficiency in a Phenotypically Diverse Cohort of 27 Natural History Study Participants

Re-evaluation of Genotype-Phenotype Correlations i...

81

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances Porphyrin Clearance in Porphyrias with Hepatic Involvement

Inhibiting Wnt/β-catenin-mTOR Signaling Enhances P...

2374

Multi-Omic Evaluation of Glycosylation Restoration Therapy in SLC35A2-CDG

Multi-Omic Evaluation of Glycosylation Restoration...

47

Defining the Genotype-CRIM Status Relationship in a Large Cohort of 215 Patients with Infantile-onset Pompe Disease

Defining the Genotype-CRIM Status Relationship in ...

102

Growth Outcomes and Safety of Navepegritide in Children with Achondroplasia: Results of the ApproaCH Trial Open Label Extension

Growth Outcomes and Safety of Navepegritide in Chi...

750

Mitochondrial Function in Fibroblasts from a Patient with Congenital NAD Deficiency due to Biallelic NADSYN1 Variants

Mitochondrial Function in Fibroblasts from a Patie...

95

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLATION IN THE MOUSE BRAIN

PROTEIN TARGETS OF CO2-DEPENDENT LYSINE CARBOXYLAT...

140

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

539

Gestational diabetes therapeutics

Gestational diabetes therapeutics

633

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

585

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

928

Different types of Alzheimer's disease

Different types of Alzheimer's disease

680

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

616

Alzheimer’s therapeutics

Alzheimer’s therapeutics

760

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

643

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

652

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

591

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

587

APOE in Alzheimer’s

APOE in Alzheimer’s

818

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

744

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

928

Different types of Alzheimer's disease

Different types of Alzheimer's disease

680

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

616

Alzheimer’s therapeutics

Alzheimer’s therapeutics

760

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

643

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

652

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

591

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

587

APOE in Alzheimer’s

APOE in Alzheimer’s

818

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

744

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

576

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

751

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

536

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

539

Gestational diabetes therapeutics

Gestational diabetes therapeutics

633

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

585