Index - Sciencemission

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

Science Hangouts

From development to evolution: Common dynamic mechanisms shaping our brains and underlying disease

22

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

Science Hangouts

Xenobiotic Disruption of the Microbiome and Metabolic Consequences

21

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

109

Dynamic Memory

Science Hangouts

Dynamic Memory

17

Science News Highlights

Structural insights into diverse mechanisms of CDK regulation

News highlights

Structural insights into diverse mechanisms of CDK regulation

6

Neurobiology of prolonged grief disorder

News highlights

Neurobiology of prolonged grief disorder

8

Ischemia derived extracellular vesicles drive non-infarcted region degeneration

News highlights

Ischemia derived extracellular vesicles drive non-infa...

17

News

Keeping cells’ recycling system in balance

Keeping cells’ recycling system in balance

11

Physical pressure triggers neurons’ self-destruction programming

Physical pressure triggers neurons’ self-destructi...

20

Blood-based tests show strong promise for dementia diagnosis

Blood-based tests show strong promise for dementia...

21

Identifying aggressive prostate cancer with multi-omics

Identifying aggressive prostate cancer with multi-...

33

Role of microglia in regulating hippocampal adult neurogenesis

Role of microglia in regulating hippocampal adult ...

52

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

29

Radiotherapy is more effective when administered at the right time of day

Radiotherapy is more effective when administered a...

26

New gatekeeper cell in the brain

New gatekeeper cell in the brain

38

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

17

Exercise trains a mouse's brain to build endurance

Exercise trains a mouse's brain to build endurance

26

Brain circuit and cells that link prior experiences to appetite identified!

Brain circuit and cells that link prior experience...

20

How the cells compensate for the faulty transcription?

How the cells compensate for the faulty transcript...

30

The dynamics of myelin swellings

The dynamics of myelin swellings

26

Physical pressure triggers neurons’ self-destruction programming

Physical pressure triggers neurons’ self-destructi...

20

Blood-based tests show strong promise for dementia diagnosis

Blood-based tests show strong promise for dementia...

21

Role of microglia in regulating hippocampal adult neurogenesis

Role of microglia in regulating hippocampal adult ...

52

New gatekeeper cell in the brain

New gatekeeper cell in the brain

38

Exercise trains a mouse's brain to build endurance

Exercise trains a mouse's brain to build endurance

26

Brain circuit and cells that link prior experiences to appetite identified!

Brain circuit and cells that link prior experience...

20

The dynamics of myelin swellings

The dynamics of myelin swellings

26

A drug to cure jet lag?

A drug to cure jet lag?

52

PD as a SCAN disorder!

PD as a SCAN disorder!

25

Characterizing human dermal sleeping pain neurons

Characterizing human dermal sleeping pain neurons

26

Convergent molecular pathways across distinct genetic forms of autism

Convergent molecular pathways across distinct gen...

16

Stress-related memory issues in women from high estrogen levels in brain

Stress-related memory issues in women from high es...

26

Aging brains pile up damaged synaptic proteins in microglia

Aging brains pile up damaged synaptic proteins in ...

100

Identifying aggressive prostate cancer with multi-omics

Identifying aggressive prostate cancer with multi-...

33

Radiotherapy is more effective when administered at the right time of day

Radiotherapy is more effective when administered a...

26

Chronic cellular stress promotes liver cancer but also enhances immunotherapy efficiency

Chronic cellular stress promotes liver cancer but ...

40

How extra cellular matrix boosts triple negative breast cancer’s ability to metastasize

How extra cellular matrix boosts triple negative b...

33

How microRNA regulates intratumoral heterogeneity

How microRNA regulates intratumoral heterogeneity

35

What causes human cancers?

What causes human cancers?

85

Small number of ‘highly plastic’ cancer cells drive disease progression and treatment resistance

Small number of ‘highly plastic’ cancer cells driv...

34

Blood test can to identify cancer in patients with non-specific symptoms

Blood test can to identify cancer in patients with...

63

Chemotherapy rewires gut bacteria to curb metastasis

Chemotherapy rewires gut bacteria to curb metastasis

68

How cancer cells protect themselves from the immune system

How cancer cells protect themselves from the immun...

82

A novel mechanism for cancer-associated weight loss

A novel mechanism for cancer-associated weight loss

86

Tissue-resident microbiota impacts colorectal cancer progression and prognosis

Tissue-resident microbiota impacts colorectal canc...

55

Inflammation fuels one of the most aggressive forms of cancer

Inflammation fuels one of the most aggressive form...

111

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

50

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

71

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

40

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

67

Exposure to natural light improves metabolic health

Exposure to natural light improves metabolic health

92

Gut microbial bileacids in infancy may influence the risk of type 1 diabetes

Gut microbial bileacids in infancy may influence t...

54

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

50

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

171

How the Immune System Stalls Weight Loss

How the Immune System Stalls Weight Loss

159

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

312

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

161

Mitochondrial ketone body oxidation impaired in diabetes & liver disease

Mitochondrial ketone body oxidation impaired in di...

136

Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

Sons of mothers with type 1 diabetes show early si...

88

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

43

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

33

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

71

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

83

Gene therapy for chronic pain?

Gene therapy for chronic pain?

59

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

68

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

53

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

59

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

57

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

87

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

123

AI-based software maps proteins and lipids within cells

AI-based software maps proteins and lipids within ...

102

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

117

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

56

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

36

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

62

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

109

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

93

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

112

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

146

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

121

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

153

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

177

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

151

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

333

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

309

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

52

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

180

How cell walls guide stem cells

How cell walls guide stem cells

52

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

72

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

72

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

81

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

59

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

55

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

95

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

187

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

73

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

95

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

84

How longevity is inherited across generations

How longevity is inherited across generations

84

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

37

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

72

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

54

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

43

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

83

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

66

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

63

Gene linked with risk of delirium

Gene linked with risk of delirium

65

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

97

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

90

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

110

A genome-to-proteome map

A genome-to-proteome map

124

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

63

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

71

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

111

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

398

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

416

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

385

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

414

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

284

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

374

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

433

Role of ECM in brain memory

Role of ECM in brain memory

376

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

391

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

392

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

44

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

34

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

43

A novel inflammatory function of platelets

A novel inflammatory function of platelets

52

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

55

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

68

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

62

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

92

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

98

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

76

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

112

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

78

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

97

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

29

sncRNAs in sperm aging

sncRNAs in sperm aging

29

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

82

How reproductive organs form

How reproductive organs form

67

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

94

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

81

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

114

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

168

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

119

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

86

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

100

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

105

Functional eggs from human skin cells

Functional eggs from human skin cells

96

Keeping cells’ recycling system in balance

Keeping cells’ recycling system in balance

11

How the cells compensate for the faulty transcription?

How the cells compensate for the faulty transcript...

30

ER remodelling in ageing!

ER remodelling in ageing!

19

GlycoRNA’s control growth factor signaling!

GlycoRNA’s control growth factor signaling!

75

Bile acid transport mechanism

Bile acid transport mechanism

40

Compensatory epigenetic mechanisms to control genes

Compensatory epigenetic mechanisms to control genes

23

New drug candidate reverses metabolic liver disease and fibrosis

New drug candidate reverses metabolic liver diseas...

93

In vitro transcription may be getting cheaper!

In vitro transcription may be getting cheaper!

38

Why face scars less than the body

Why face scars less than the body

47

Substrate recognition mechanism of Golgi membrane-associated degradation (GOMED)

Substrate recognition mechanism of Golgi membrane-...

48

Cas12a3 cleaves tRNA tails!

Cas12a3 cleaves tRNA tails!

51

Repairing damaged lysosomal membrane

Repairing damaged lysosomal membrane

81

Regulating protein production

Regulating protein production

57

How respiratory bacterium obtains essential lipids from the host

How respiratory bacterium obtains essential lipids...

18

How both human and bacterial genes shape oral microbiome

How both human and bacterial genes shape oral micr...

70

Previously unknown bacterial component in kidney stone formation

Previously unknown bacterial component in kidney s...

27

Gut bacteria may tip the balance between feeding tumors and fueling immunity

Gut bacteria may tip the balance between feeding t...

70

How light suppresses virulence in antibiotic-resistant pathogen

How light suppresses virulence in antibiotic-resis...

69

Breath carries clues to gut microbiome health

Breath carries clues to gut microbiome health

44

A protein found in the GI tract can neutralize many bacteria

A protein found in the GI tract can neutralize man...

86

Replacing microbiota makes aging intestines young again

Replacing microbiota makes aging intestines young ...

67

New treatment for drug-resistant fungal infections

New treatment for drug-resistant fungal infections

52

Microbes in breast milk help populate infant gut microbiomes

Microbes in breast milk help populate infant gut m...

53

Virus-drug structure, interaction in real time

Virus-drug structure, interaction in real time

66

A high-protein diet can defeat cholera infection

A high-protein diet can defeat cholera infection

66

Small RNA coded by phage controls infection

Small RNA coded by phage controls infection

71

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

52

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

43

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

119

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

110

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

112

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

121

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

197

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

265

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

300

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

314

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

286

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

302

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

421

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

83

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

172

How cucumbers got longer?

How cucumbers got longer?

135

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

88

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

107

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

93

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

160

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

367

How plants sense heat during the day

How plants sense heat during the day

327

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

299

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

348

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

352

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

377

How a common immunosuppressive drug “ATG” injures liver blood vessels

How a common immunosuppressive drug “ATG” injures ...

22

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

27

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

54

Fat surrounding the colon interacts with the immune system

Fat surrounding the colon interacts with the immun...

121

How inflammatory bowel disease promotes colorectal cancer

How inflammatory bowel disease promotes colorectal...

89

How gut pain-sensing neurons elicit immune response

How gut pain-sensing neurons elicit immune response

67

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

112

Human T-cell receptor–CD3 complex structure unraveled!

Human T-cell receptor–CD3 complex structure unrave...

88

Key lung immune cells can intensify allergic reactions

Key lung immune cells can intensify allergic react...

228

A new vulnerability of asthma immune cells discovered

A new vulnerability of asthma immune cells discovered

90

Why the 'gut brain' plays a central role for allergies

Why the 'gut brain' plays a central role for aller...

102

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

72

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

123

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

81

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

366

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

262

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

723

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

345

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

331

Printed skin to replace animal testing

Printed skin to replace animal testing

342

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

316

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

336

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

360

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

363

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

17

How bacteria bind to different types of cells

How bacteria bind to different types of cells

14

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

35

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

29

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

40

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

45

‘Revoice’ device gives stroke patients their voice back

‘Revoice’ device gives stroke patients their voice...

58

Specialized transporters relay lipids to cellular targets

Specialized transporters relay lipids to cellular ...

53

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

52

Redox and pH changes shuts down AQP3 channel

Redox and pH changes shuts down AQP3 channel

78

Mapping the human genome in 4D

Mapping the human genome in 4D

105

Using a microfluidic device to monitor glioblastoma treatment outcomes

Using a microfluidic device to monitor glioblastom...

56

Enzyme catalysis using thiol switching!

Enzyme catalysis using thiol switching!

67

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

105

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

297

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

286

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

302

How the brain regulates emotions

How the brain regulates emotions

379

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

377

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

364

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

410

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

378

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

382

Link between dietary choices and brain health

Link between dietary choices and brain health

354

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

302

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

431

Research

Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans

Mechanical compression induces neuronal apoptosis,...

9

Diversity in CDK structural mechanisms of regulation and drug discovery opportunities

Diversity in CDK structural mechanisms of regulati...

11

A neurobiological perspective on prolonged grief disorder

A neurobiological perspective on prolonged grief d...

26

Migraine

Migraine

9

Mitochondrial fission during mitophagy requires both inner and outer mitofissins

Mitochondrial fission during mitophagy requires bo...

20

Spatial multi-omics identifies aggressive prostate cancer signatures highlighting pro- inflammatory chemokine activity in the tumor microenvironment

Spatial multi-omics identifies aggressive prostat...

18

Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice

Inhibition of TGF-β signaling in microglia stimula...

25

Dementia

52

Penumbra-derived small extracellular vesicles carry pathogenic RNA driving remote damage after cortical infarction

Penumbra-derived small extracellular vesicles car...

23

Type 1 Diabetes

Type 1 Diabetes

63

Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia

Tumor-immune-neural circuit disrupts energy homeos...

44

Circadian regulation of homologous recombination by cryptochrome1-mediated dampening of DNA end resection

Circadian regulation of homologous recombination b...

16

Base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Base barrier cells provide compartmentalization of...

18

Mechanical compression induces neuronal apoptosis, reduces synaptic activity, and promotes glial neuroinflammation in mice and humans

Mechanical compression induces neuronal apoptosis,...

9

Diversity in CDK structural mechanisms of regulation and drug discovery opportunities

Diversity in CDK structural mechanisms of regulati...

11

A neurobiological perspective on prolonged grief disorder

A neurobiological perspective on prolonged grief d...

26

Mitochondrial fission during mitophagy requires both inner and outer mitofissins

Mitochondrial fission during mitophagy requires bo...

20

Spatial multi-omics identifies aggressive prostate cancer signatures highlighting pro- inflammatory chemokine activity in the tumor microenvironment

Spatial multi-omics identifies aggressive prostat...

18

Inhibition of TGF-β signaling in microglia stimulates hippocampal adult neurogenesis and reduces anxiety-like behavior in adult mice

Inhibition of TGF-β signaling in microglia stimula...

25

Penumbra-derived small extracellular vesicles carry pathogenic RNA driving remote damage after cortical infarction

Penumbra-derived small extracellular vesicles car...

23

Type 1 Diabetes

Type 1 Diabetes

63

Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia

Tumor-immune-neural circuit disrupts energy homeos...

44

Circadian regulation of homologous recombination by cryptochrome1-mediated dampening of DNA end resection

Circadian regulation of homologous recombination b...

16

Base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Base barrier cells provide compartmentalization of...

18

The redox driven Na+-pumping mechanism in Vibrio cholerae NADH-quinone oxidoreductase relies on dynamic conformational changes

The redox driven Na+-pumping mechanism in Vibrio c...

12

Mitochondrial transfer from immune to tumor cells enables lymph node metastasis

Mitochondrial transfer from immune to tumor cells ...

40

A unified framework combining linear and 3D molecular features for robust drug-protein interaction prediction

A unified framework combining linear and 3D molecu...

44

Multi-omic analysis of guided and unguided forebrain organoids reveals differences in cellular composition and metabolic profiles

Multi-omic analysis of guided and unguided forebra...

51

3D multiparametric ultrasound imaging of steatotic liver disease in a study with male rats

3D multiparametric ultrasound imaging of steatotic...

50

A universal polyphosphate kinase powers in vitro transcription

A universal polyphosphate kinase powers in vitro t...

60

Fluorescent indicators for visualizing dynamic contact between cells and between processes originating from a single cell

Fluorescent indicators for visualizing dynamic con...

61

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics

HT SpaceM: A high-throughput and reproducible meth...

64

Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

Chimeric brain models to study human glial-neurona...

67

Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Mapping cellular targets of covalent cancer drugs ...

83

Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel

Dynamic release of extracellular particles after o...

74

Activation of enzymatic catalysis via nucleic acid hybridization affords synergistic coupling of specificity, potency, and signal amplification

Activation of enzymatic catalysis via nucleic acid...

71

Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities

Spatially resolved microRNA expression in tissues:...

74

CaBLAM: a high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

CaBLAM: a high-contrast bioluminescent Ca2+ indica...

67

Nondestructive X-ray tomography of brain tissue ultrastructure

Nondestructive X-ray tomography of brain tissue ul...

54

Migraine

Migraine

9

Dementia

Dementia

52

Trisomy

Trisomy

34

Cystic Fibrosis

Cystic Fibrosis

41

Brainstem lesions

Brainstem lesions

63

THE LIMBIC SYSTEM

THE LIMBIC SYSTEM

212

MITOCHONDRIAL DISEASES

MITOCHONDRIAL DISEASES

174

NEURO- MUSCULAR JUNCTION

NEURO- MUSCULAR JUNCTION

116

Caffeine

138

Diabetic Neuropathy

Diabetic Neuropathy

111

Neural Transmission

Neural Transmission

109

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

105

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

320

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

72369

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1170

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1079

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3494

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

368

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

363

HEAD AND NECK CANCER

HEAD AND NECK CANCER

384

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

228

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

353

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

398

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

341

Gestational diabetes therapeutics

Gestational diabetes therapeutics

335

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

360

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

532

Different types of Alzheimer's disease

Different types of Alzheimer's disease

434

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

396

Alzheimer’s therapeutics

Alzheimer’s therapeutics

393

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

387

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

411

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

359

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

377

APOE in Alzheimer’s

APOE in Alzheimer’s

441

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

511

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

532

Different types of Alzheimer's disease

Different types of Alzheimer's disease

434

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

396

Alzheimer’s therapeutics

Alzheimer’s therapeutics

393

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

387

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

411

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

359

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

377

APOE in Alzheimer’s

APOE in Alzheimer’s

441

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

511

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

369

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

404

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

345

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

341

Gestational diabetes therapeutics

Gestational diabetes therapeutics

335

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

360