Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

8894

Motivation and Pleasure in Psychosis?

Science Hangouts

Motivation and Pleasure in Psychosis?

96

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

Science Hangouts

NLRC5/CITA: a critical regulator of MHC class I antigen-presentation and cancer immunity

105

Science News Highlights

mRNA decay pathways are linked to intrinsically disordered regions of RNA binding proteins

News highlights

mRNA decay pathways are linked to intrinsically disordered regions of RNA binding proteins

7

Targeting TDP-43 is neuroprotective in amyotrophic lateral sclerosis

News highlights

Targeting TDP-43 is neuroprotective in amyotrophic lat...

8

Gene therapy for spinocerebellar ataxias

News highlights

Gene therapy for spinocerebellar ataxias

10

News

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

0

Air-permeable hydrogels!

Air-permeable hydrogels!

12

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

13

Why microglial TDP-43 loss of function leads to neurological diseases

Why microglial TDP-43 loss of function leads to ne...

36

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

20

Mechanism linking inflammation and prevention of neuron formation identified!

Mechanism linking inflammation and prevention of n...

40

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

25

How astrocytes help memories last

How astrocytes help memories last

38

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

24

AI test to predict recurrence of breast cancer

AI test to predict recurrence of breast cancer

24

Reason for gum disease in Down syndrome

Reason for gum disease in Down syndrome

28

How malaria parasites invade human cells

How malaria parasites invade human cells

40

Early warning sign of Alzheimer’s!

Early warning sign of Alzheimer’s!

42

Why microglial TDP-43 loss of function leads to neurological diseases

Why microglial TDP-43 loss of function leads to ne...

36

How astrocytes help memories last

How astrocytes help memories last

38

Reason for gum disease in Down syndrome

Reason for gum disease in Down syndrome

28

Early warning sign of Alzheimer’s!

Early warning sign of Alzheimer’s!

42

Ameliorating Huntington’s disease

Ameliorating Huntington’s disease

28

A protein involved in intercellular tau transmission identified!

A protein involved in intercellular tau transmissi...

72

How bilingual brains navigate between languages?

How bilingual brains navigate between languages?

30

Neural responses during movie viewing

Neural responses during movie viewing

40

Sex-specific immune pathway in deadly brain cancer

Sex-specific immune pathway in deadly brain cancer

58

Ancient neurons control attention

Ancient neurons control attention

44

Potential blood RNA biomarkers for Alzheimer’s disease identified!

Potential blood RNA biomarkers for Alzheimer’s dis...

59

Proteotoxic stress causes karyoptosis mediated cell death and neurodegeneration

Proteotoxic stress causes karyoptosis mediated cel...

61

Molecular basis of human daylight vision

Molecular basis of human daylight vision

57

A high-fat diet affects tumor-to-nerve signaling and promotes cachexia

A high-fat diet affects tumor-to-nerve signaling a...

43

Cuproptosis-immunity crosstalk to overcome immunotherapy resistance

Cuproptosis-immunity crosstalk to overcome immunot...

66

Inducing cell death in pancreatic cancer cells

Inducing cell death in pancreatic cancer cells

91

How colorectal cancer cells maintain high iron levels

How colorectal cancer cells maintain high iron levels

50

How physical activity may protect older adults against cancer

How physical activity may protect older adults aga...

70

Telomeres and centromeres interact in some aggressive cancers

Telomeres and centromeres interact in some aggress...

58

Engineered Salmonella bacteria to treat solid tumors

Engineered Salmonella bacteria to treat solid tumors

56

Gene linking the trade-off between youth and longevity uncovered!

Gene linking the trade-off between youth and longe...

61

Blood test detects early signs of breast cancer recurrence

Blood test detects early signs of breast cancer re...

69

Nervous system helps lung cancer evade the immune system

Nervous system helps lung cancer evade the immune ...

60

How chemotherapy influences cancer inflammation

How chemotherapy influences cancer inflammation

77

DNA repair protein creates DNA damage similar to BRCA mutations

DNA repair protein creates DNA damage similar to B...

106

Selective degradation of proteins involved in pathological processes

Selective degradation of proteins involved in path...

98

Gut microbiota can predict risk of type 2 diabetes years before it develops

Gut microbiota can predict risk of type 2 diabetes...

25

Epigenetic drugs could protect blood vessels in obesity and diabetes

Epigenetic drugs could protect blood vessels in ob...

58

Father’s obesity may lead to mitochondrial disfunction in children

Father’s obesity may lead to mitochondrial disfunc...

85

Weight-loss drugs inhibit brain’s reward system

Weight-loss drugs inhibit brain’s reward system

121

Obesity leaves a lasting memory in immune cells

Obesity leaves a lasting memory in immune cells

121

A new circadian lipid trafficking mechanism in liver

A new circadian lipid trafficking mechanism in liver

109

DNA methylation in islet cells in human ageing and diabetes

DNA methylation in islet cells in human ageing and...

127

GLP-1 medicine improves liver health independent of weight loss

GLP-1 medicine improves liver health independent o...

135

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

148

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

134

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

144

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

156

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

173

AI test to predict recurrence of breast cancer

AI test to predict recurrence of breast cancer

24

AI discovers sudden cardiac death ECG biomarker

AI discovers sudden cardiac death ECG biomarker

39

AI detects antibiotic candidates in prion proteins

AI detects antibiotic candidates in prion proteins

59

AI adds speed and geometric precision to medical imaging

AI adds speed and geometric precision to medical i...

57

AI to evaluate changes in molecular condensates

AI to evaluate changes in molecular condensates

59

A blood signature for lung cancer risk

A blood signature for lung cancer risk

80

MouseMapper AI reveals hidden whole-body-damage caused by obesity

MouseMapper AI reveals hidden whole-body-damage ca...

90

AI to design miniproteins targeting GPCRs

AI to design miniproteins targeting GPCRs

123

AI tool to bridge gene regulation and cell fate decisions

AI tool to bridge gene regulation and cell fate de...

166

Genetics of blood proteins!

Genetics of blood proteins!

69

FaceAge AI tool predicts cancer patients survival

FaceAge AI tool predicts cancer patients survival

69

A potassium-gated ion channel identified!

A potassium-gated ion channel identified!

117

AI model for protein-protein interaction modeling

AI model for protein-protein interaction modeling

124

Protein-based data storage

Protein-based data storage

63

Quantification of tandem repeats in native RNA

Quantification of tandem repeats in native RNA

73

Microrobotics technology to help transform cancer treatments of the future

Microrobotics technology to help transform cancer ...

83

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

216

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

154

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

189

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

248

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

235

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

219

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

259

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

232

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

266

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

281

Multipotent progenitors protect blood cell production and function

Multipotent progenitors protect blood cell product...

20

Mechanism linking inflammation and prevention of neuron formation identified!

Mechanism linking inflammation and prevention of n...

40

Rare stem T cells may hold the key to fighting chronic diseases

Rare stem T cells may hold the key to fighting chr...

28

Antibiotics reverse damage caused to blood stem cells by chronic Salmonella

Antibiotics reverse damage caused to blood stem ce...

38

How psychological stress alters gut microbes and ages blood stem cells

How psychological stress alters gut microbes and a...

53

High fructose during pregnancy impairs stem cell function in the fetal brain

High fructose during pregnancy impairs stem cell f...

35

“Wnt secreting organizers” in organoids to improve kidney diseases

“Wnt secreting organizers” in organoids to improve...

37

Microtubule-associated proteins regulate neural stem cell fate and disease

Microtubule-associated proteins regulate neural st...

40

Ubiquitin-like modifiers drive healthy skin development

Ubiquitin-like modifiers drive healthy skin develo...

34

A renewable cell source for cancer immunotherapy

A renewable cell source for cancer immunotherapy

55

Reversing nerve damage in human corticospinal organoid-slice connectoid model

Reversing nerve damage in human corticospinal orga...

53

Zinc finger proteins act on gene promoters to control differentiation of stem cells

Zinc finger proteins act on gene promoters to cont...

62

Identifying the ‘organizer’ cells that build bone marrow

Identifying the ‘organizer’ cells that build bone ...

77

Genetic variants linked to severe COVID-19 and lung disease risk

Genetic variants linked to severe COVID-19 and lun...

26

Gestational diabetes shares strong genetic links with type 2 diabetes

Gestational diabetes shares strong genetic links w...

50

Hereditary epilepsy successfully treated in mouse model

Hereditary epilepsy successfully treated in mouse ...

51

Same genetic deletion leads to different neurodevelopmental disorders

Same genetic deletion leads to different neurodeve...

81

Mental and physical illnesses go hand in hand!

Mental and physical illnesses go hand in hand!

106

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

106

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

127

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

141

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

126

How longevity is inherited across generations

How longevity is inherited across generations

197

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

154

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

182

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

153

Mitochondrial complex I dysfunction treated with hypoxia

Mitochondrial complex I dysfunction treated with h...

0

How life experiences can shape aging in multiple tissues

How life experiences can shape aging in multiple t...

46

Kidney injury repair using a humanized monoclonal antibody

Kidney injury repair using a humanized monoclonal ...

41

A molecular linchpin for muscle health identified!

A molecular linchpin for muscle health identified!

45

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

138

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

166

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

174

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

203

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

508

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

510

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

496

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

576

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

402

Molecular pathway driving aortic disease in Marfan syndrome

Molecular pathway driving aortic disease in Marfan...

24

Molecular mechanics behind heart cell restructuring revealed

Molecular mechanics behind heart cell restructurin...

62

Alternative splicing in heart development and disease

Alternative splicing in heart development and disease

47

Age does not appear to drive cardiovascular risk in pregnancy

Age does not appear to drive cardiovascular risk i...

48

Role of purine metabolism in atherosclerosis

Role of purine metabolism in atherosclerosis

74

Mutations in gene regulatory region linked to heart valve defect

Mutations in gene regulatory region linked to hea...

67

The beating of the heart suppresses growth in cardiac cancers

The beating of the heart suppresses growth in card...

97

Mechanisms of aortic aneurysm progression

Mechanisms of aortic aneurysm progression

67

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

166

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

130

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

149

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

138

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

148

Mothers’ prenatal immunity shapes lifelong resistance to gum disease

Mothers’ prenatal immunity shapes lifelong resista...

70

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

103

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

135

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

128

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

165

sncRNAs in sperm aging

sncRNAs in sperm aging

211

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

191

How reproductive organs form

How reproductive organs form

251

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

184

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

188

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

225

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

261

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

226

How malaria parasites invade human cells

How malaria parasites invade human cells

40

Mechanism of bacterial membrane protein insertion

Mechanism of bacterial membrane protein insertion

47

Small-molecule inhibitors for β-arrestin proteins

Small-molecule inhibitors for β-arrestin proteins

32

Low-protein, methionine-supplemented ‘longevity diet’ linked to longer healthy lifespan

Low-protein, methionine-supplemented ‘longevity di...

60

Allosteric regulation of protein kinase Cβ

Allosteric regulation of protein kinase Cβ

29

How large proteins cross cell membranes

How large proteins cross cell membranes

46

FGF21 helps cells cope with protein folding stress

FGF21 helps cells cope with protein folding stress

49

Structural basis for RNA-based gene silencing

Structural basis for RNA-based gene silencing

46

Mitochondria tethered to the nuclear pore complex provides energy supply

Mitochondria tethered to the nuclear pore complex ...

76

RNA’s hidden role as protein chaperone

RNA’s hidden role as protein chaperone

166

Collagen forms condensate inside cells

Collagen forms condensate inside cells

73

A targeted RNA cleavage and repair method, to fix dysfunctional RNA

A targeted RNA cleavage and repair method, to fix ...

55

Role of condensates in signaling

Role of condensates in signaling

86

Gut bacteria linked to frailty in older women

Gut bacteria linked to frailty in older women

13

Structural insight into the mechanism of bacterial pili retraction

Structural insight into the mechanism of bacterial...

35

Microbiota’s hidden role in mosquito-borne disease

Microbiota’s hidden role in mosquito-borne disease

65

Colorectal cancer signature

Colorectal cancer signature

34

How bacteria use circadian clocks to colonize

How bacteria use circadian clocks to colonize

22

A kinase integrating metabolic control with tuberculosis virulence identified!

A kinase integrating metabolic control with tuberc...

32

Bacteria share proteins under antibiotic stress!

Bacteria share proteins under antibiotic stress!

39

Antiviral molecules in bacteria

Antiviral molecules in bacteria

42

Mechanism of immune evasion by Borrelia recurrentis

Mechanism of immune evasion by Borrelia recurrentis

33

A new natural depsipeptide antibiotic discovered!

A new natural depsipeptide antibiotic discovered!

24

How cells fight infection from the inside

How cells fight infection from the inside

52

Gut microbe found to worsen sepsis

Gut microbe found to worsen sepsis

45

A link between autoantibodies and neurological symptoms in long COVID

A link between autoantibodies and neurological sym...

47

Role for NANOG in human embryogenesis

Role for NANOG in human embryogenesis

54

The role of signaling pathways timing in brain development

The role of signaling pathways timing in brain dev...

64

Early brain activity shape vocal circuits!

Early brain activity shape vocal circuits!

57

Mechanism of collective cellular migration and invasion

Mechanism of collective cellular migration and inv...

52

A protein directs neuronal migration in the embryonic brain

A protein directs neuronal migration in the embryo...

84

E. coli and 'good' bacteria balanced by breastmilk in baby gut microbiomes

E. coli and 'good' bacteria balanced by breastmilk...

64

The mechanics behind neural tube closure!

The mechanics behind neural tube closure!

73

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

88

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

89

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

97

A developmental atlas for genes and cells

A developmental atlas for genes and cells

139

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

161

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

131

Mechanisms for plant cell stability in drought

Mechanisms for plant cell stability in drought

38

Plants reduce iron uptake when stressed

Plants reduce iron uptake when stressed

43

Cure for dry eye disease

Cure for dry eye disease

65

Garlic kills mosquitoes’ mood too!

Garlic kills mosquitoes’ mood too!

70

A new mechanism of activation of plants immune defenses by soil bacteria

A new mechanism of activation of plants immune def...

105

Maintaining stability of the plant proteome and controlling stress responses

Maintaining stability of the plant proteome and co...

87

Key gene for perennial growth in wild rice identified!

Key gene for perennial growth in wild rice identif...

89

Nicotine Biosynthesis!

Nicotine Biosynthesis!

186

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

121

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

211

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

114

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

120

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

186

Immune cell–fibroblast crosstalk may may drive progression of autoimmune diseases

Immune cell–fibroblast crosstalk may may drive pro...

33

How mutations affect STING-induced immunity

How mutations affect STING-induced immunity

53

How newly identified immune cells, ruptoblasts, protect the body

How newly identified immune cells, ruptoblasts, pr...

42

Nutrient in breast milk that shapes immune development

Nutrient in breast milk that shapes immune develop...

36

Body clock found to control inflammatory responses in macrophages

Body clock found to control inflammatory responses...

70

How the body remembers the tumor?

How the body remembers the tumor?

94

Molecular mechanisms to maintain intestinal barrier function

Molecular mechanisms to maintain intestinal barrie...

81

Reversing chromatin aging with SIRT6 overexpression

Reversing chromatin aging with SIRT6 overexpression

129

Molecule linked to treatment-resistant inflammatory bowel disease identified!

Molecule linked to treatment-resistant inflammator...

63

A key protein in the inflammatory response to infections identified

A key protein in the inflammatory response to infe...

69

Proper protein recycling helps exhausted immune cells fight tumors

Proper protein recycling helps exhausted immune ce...

73

How immune cell networks drive liver disease

How immune cell networks drive liver disease

85

NO-independent inflammatory response by iNOS

NO-independent inflammatory response by iNOS

84

Air-permeable hydrogels!

Air-permeable hydrogels!

12

Temperature behaves differently in the cell

Temperature behaves differently in the cell

49

Engineering faster, more effective blood clots

Engineering faster, more effective blood clots

55

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

88

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

94

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

186

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

469

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

369

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

828

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

455

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

437

Printed skin to replace animal testing

Printed skin to replace animal testing

435

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

426

A high-throughput platform to track lipids in action with biosensors

A high-throughput platform to track lipids in acti...

34

Platform for automated cryo-EM sample preparation and quality control

Platform for automated cryo-EM sample preparation ...

41

Tracking iron and oxygen levels in cells using LiON

Tracking iron and oxygen levels in cells using LiON

44

Gene transcription measurement in the living brain

Gene transcription measurement in the living brain

58

How the brain takes out its trash

How the brain takes out its trash

72

Single-cell method for mapping DNA-protein interactions

Single-cell method for mapping DNA-protein interac...

91

Ultrasound to alter how the brain responds to pain

Ultrasound to alter how the brain responds to pain

67

Surprising cellular dynamics of the aging brain

Surprising cellular dynamics of the aging brain

116

New CRISPR tool eliminates undesired cells

New CRISPR tool eliminates undesired cells

94

Multiplexed MRI provides a comprehensive view of the human brain

Multiplexed MRI provides a comprehensive view of t...

92

“Aging clocks” to measure body decline

“Aging clocks” to measure body decline

75

“MitoCatch” delivers healthy mitochondria to diseased cells

“MitoCatch” delivers healthy mitochondria to disea...

147

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

101

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

199

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

398

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

404

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

394

How the brain regulates emotions

How the brain regulates emotions

573

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

466

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

451

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

507

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

468

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

471

Link between dietary choices and brain health

Link between dietary choices and brain health

445

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

415

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

534

Research

Hypoxia rescues complex 1-associated disease caused by proteostatic defects

Hypoxia rescues complex 1-associated disease cause...

2

Air-permeable hydrogels through viscoelastic phase separation of aerogels

Air-permeable hydrogels through viscoelastic phase...

14

Gut microbiota associates with frailty in older women

Gut microbiota associates with frailty in older women

14

Intrinsically disordered regions in eukaryotic mRNA decay pathways

Intrinsically disordered regions in eukaryotic mRN...

24

Therapeutic targeting of the conserved region within the low-complexity domain of TDP-43 is neuroprotective and extends survival in amyotrophic lateral sclerosis mice

Therapeutic targeting of the conserved region with...

24

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice

Microglial TDP-43 mediates myelin refinement and r...

25

Aging of hematopoietic stem cells is inconsequential to progenitor cell function

Aging of hematopoietic stem cells is inconsequenti...

24

Gene therapy for spinocerebellar ataxias

Gene therapy for spinocerebellar ataxias

36

A unified mechanism of phosphate export across eukaryotes through EXS domain-containing proteins

A unified mechanism of phosphate export across euk...

34

Neuron–tumor communication in solid tumors: from bona fide synapses to pseudo-synaptic neural interfaces☆

Neuron–tumor communication in solid tumors: from b...

724

TNF-α induces type I IFN signalling to suppress neurogenesis and recruit T cells

TNF-α induces type I IFN signalling to suppress ne...

16

Gut microbiome composition and functional potential associate with incident type 2 diabetes in 4,685 adults from a Swedish prospective cohort

Gut microbiome composition and functional potentia...

35

Astrocytic ankyrin-2 enables memory persistence in the mouse hippocampus

Astrocytic ankyrin-2 enables memory persistence in...

18

Hypoxia rescues complex 1-associated disease caused by proteostatic defects

Hypoxia rescues complex 1-associated disease cause...

2

Air-permeable hydrogels through viscoelastic phase separation of aerogels

Air-permeable hydrogels through viscoelastic phase...

14

Gut microbiota associates with frailty in older women

Gut microbiota associates with frailty in older women

14

Intrinsically disordered regions in eukaryotic mRNA decay pathways

Intrinsically disordered regions in eukaryotic mRN...

24

Therapeutic targeting of the conserved region within the low-complexity domain of TDP-43 is neuroprotective and extends survival in amyotrophic lateral sclerosis mice

Therapeutic targeting of the conserved region with...

24

Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice

Microglial TDP-43 mediates myelin refinement and r...

25

Aging of hematopoietic stem cells is inconsequential to progenitor cell function

Aging of hematopoietic stem cells is inconsequenti...

24

Gene therapy for spinocerebellar ataxias

Gene therapy for spinocerebellar ataxias

36

A unified mechanism of phosphate export across eukaryotes through EXS domain-containing proteins

A unified mechanism of phosphate export across euk...

34

Neuron–tumor communication in solid tumors: from bona fide synapses to pseudo-synaptic neural interfaces☆

Neuron–tumor communication in solid tumors: from b...

724

TNF-α induces type I IFN signalling to suppress neurogenesis and recruit T cells

TNF-α induces type I IFN signalling to suppress ne...

16

Gut microbiome composition and functional potential associate with incident type 2 diabetes in 4,685 adults from a Swedish prospective cohort

Gut microbiome composition and functional potentia...

35

Astrocytic ankyrin-2 enables memory persistence in the mouse hippocampus

Astrocytic ankyrin-2 enables memory persistence in...

18

In vivo single-cell ribosome profiling reveals cell- type-specific translational programs during aging

In vivo single-cell ribosome profiling reveals cel...

66

EasyGrid: a versatile platform for automated cryo-EM sample preparation and quality control

EasyGrid: a versatile platform for automated cryo-...

76

Engineered bacterial biofilms for biotechnological applications

Engineered bacterial biofilms for biotechnological...

71

Multi-omics analysis of extracellular vesicle cargo in cancer

Multi-omics analysis of extracellular vesicle carg...

91

Plug-in hybrid baculovirus expression vector for high-yield recombinant adeno-associated virus gene therapy vector production

Plug-in hybrid baculovirus expression vector for h...

45

Engineered Bacillus subtilis to deliver dsRNA via extracellular vesicles against the H9N2 avian influenza virus

Engineered Bacillus subtilis to deliver dsRNA via ...

54

Expansion and CAR engineering of granulocyte- monocyte progenitors for cellular immunotherapy

Expansion and CAR engineering of granulocyte- mono...

50

Microelectrode array technology for organoids and microphysiological systems

Microelectrode array technology for organoids and ...

53

Adaptive Riemannian optimization for multi- scale diffeomorphic matching

Adaptive Riemannian optimization for multi- scale ...

43

Replication origin flexibility: a tool to mitigate the hazards of excess replication

Replication origin flexibility: a tool to mitigate...

46

Molecular basis of target RNA cleavage by Cas13

Molecular basis of target RNA cleavage by Cas13

49

Monitoring in vivo transcription with synthetic serum markers

Monitoring in vivo transcription with synthetic se...

59

Single-cell mapping of regulatory DNA-protein interactions

Single-cell mapping of regulatory DNA-protein inte...

62

Breeding of Cotton

Breeding of Cotton

198

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

MOTOR & SENSORY PATHWAYS OF THE NERVOUS SYSTEM

293

THALASSEMIA

THALASSEMIA

429

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

417

NMDA RECEPTORS

336

Neural Development

Neural Development

293

Transcription Factors

Transcription Factors

313

Interferons

234

RABIES

232

ANEMIA

225

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

239

Migraine

206

Dementia

258

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

138668

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1627

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1466

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

5626

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

482

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

457

HEAD AND NECK CANCER

HEAD AND NECK CANCER

562

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

332

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

464

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

497

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

445

Gestational diabetes therapeutics

Gestational diabetes therapeutics

517

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

491

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

749

Different types of Alzheimer's disease

Different types of Alzheimer's disease

583

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

509

Alzheimer’s therapeutics

Alzheimer’s therapeutics

613

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

535

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

534

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

474

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

480

APOE in Alzheimer’s

APOE in Alzheimer’s

656

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

625

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

749

Different types of Alzheimer's disease

Different types of Alzheimer's disease

583

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

509

Alzheimer’s therapeutics

Alzheimer’s therapeutics

613

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

535

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

534

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

474

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

480

APOE in Alzheimer’s

APOE in Alzheimer’s

656

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

625

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

487

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

597

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

434

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

445

Gestational diabetes therapeutics

Gestational diabetes therapeutics

517

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

491