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All Publications Protocols Presentations Posters
Harnessing indole scaffolds to identify small- molecule IRE1α inhibitors modulating XBP1  mRNA splicing

Harnessing indole scaffolds to identify small...

 6

Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics

Uncertainty-aware ensemble of foundation mode...

 7

Integrator 20th anniversary: a molecular machine indispensable in development and disease

Integrator 20th anniversary: a molecular mach...

 20

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Adult hippocampal neurogenesis: New avenues f...

 39

Harnessing indole scaffolds to identify small- molecule IRE1α inhibitors modulating XBP1  mRNA splicing

Harnessing indole scaffolds to identify small...

 6

Integrator 20th anniversary: a molecular machine indispensable in development and disease

Integrator 20th anniversary: a molecular mach...

 20

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Adult hippocampal neurogenesis: New avenues f...

 39

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brai...

 11

Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics

Uncertainty-aware ensemble of foundation mode...

 7

Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria

Genetic controllers for enhancing the evoluti...

 9

DOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction reads

DOLPHIN advances single-cell transcriptomics ...

 22

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

Human interpretable grammar encodes multicell...

 51

What is Asthma

What is Asthma

 42

Tuberculosis

Tuberculosis

 71

Anemia

Anemia

 113

What is Procrastination?

What is Procrastination?

 282

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 33407

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 988

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 923

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 1799

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Science Hangouts

Daily Well-Being
Science Hangouts

Daily Well-Being

 401

A twist of fate: age-related declines in the longevity protein, Klotho, drive impaired skeletal muscle regeneration
Science Hangouts

A twist of fate: age-related declines in the longevity protein, Klotho, drive impaired skeletal muscle regeneration

 1752

Understanding Cancer: From Development to Therapy
Science Hangouts

Understanding Cancer: From Development to Therapy

 391

Atomic Force Microscopy: Towards Medical Applications.
Science Hangouts

Atomic Force Microscopy: Towards Medical Applications.

 93

A Novel Atypical Sperm Centriole is Functional During Fertilization
Science Hangouts

A Novel Atypical Sperm Centriole is Functional During Fertilization

 93

GABAergic signaling at the Axon Initial Segment
Science Hangouts

GABAergic signaling at the Axon Initial Segment

 105

Science News Highlights

Integrator in development and disease
News highlights

Integrator in development and disease

 7

Adult hippocampal neurogenesis
News highlights

Adult hippocampal neurogenesis

 7

Neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer
News highlights

Neuron-gastric tumor organoid reveals metabolic vulner...

 7

News

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    • Genetics
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How gut bacteria adapt to new environments

How gut bacteria adapt to new environments

 4

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

 7

Disrupting stress management in cancer cells

Disrupting stress management in cancer cells

 7

AI distinguishes glioblastoma from look-alike cancers during surgery

AI distinguishes glioblastoma from look-alike canc...

 7

RNA splitting mechanism behind origin of Type V CRISPR systems

RNA splitting mechanism behind origin of Type V CR...

 20

Strategies to boost protein production from engineered cells

Strategies to boost protein production from engine...

 23

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 23

DOLPHIN for exon-level single-cell RNA-seq data analysis

DOLPHIN for exon-level single-cell RNA-seq data an...

 43

How unstructured protein segments regulate biological functions

How unstructured protein segments regulate biologi...

 35

Reading mice’s ‘thoughts’ from their facial expression

Reading mice’s ‘thoughts’ from their facial expres...

 33

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

 27

Key mechanism for appetite and weight control

Key mechanism for appetite and weight control

 55

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 52

Brain’s shifting geometry tied to memory loss, dementia risk

Brain’s shifting geometry tied to memory loss, dem...

 52

A master regulator of mitochondrial degradation and biogenesis identified!

A master regulator of mitochondrial degradation an...

 92

Stress disrupts glycosylation in the prefrontal cortex to trigger depression

Stress disrupts glycosylation in the prefrontal co...

 84

Creative experiences delay brain aging

Creative experiences delay brain aging

 124

Connection between impaired musical rhythm abilities and developmental speech-language disorders

Connection between impaired musical rhythm abiliti...

 22

Neural basis for energy expenditure in arcuate hypothalamus

Neural basis for energy expenditure in arcuate hyp...

 82

How mosquito-borne viruses breach the brain’s defenses

How mosquito-borne viruses breach the brain’s defe...

 43

Linking early life epigenetic memory to adult brain inflammation​

Linking early life epigenetic memory to adult brai...

 113

Astrocytes role in integrating multiple synapses

Astrocytes role in integrating multiple synapses

 85

Psychoactive agent protects brain vessels and reduces inflammation

Psychoactive agent protects brain vessels and redu...

 71

The first image of an open NMDA receptor

The first image of an open NMDA receptor

 42

Decoupling inflammation from pain

Decoupling inflammation from pain

 54

How does the brain differentiate painful from non-painful touch?

How does the brain differentiate painful from non-...

 54

Disrupting stress management in cancer cells

Disrupting stress management in cancer cells

 7

Glioblastomas affect much more than just the brain

Glioblastomas affect much more than just the brain

 20

Fatty acids feed cancer-promoting bacteria

Fatty acids feed cancer-promoting bacteria

 127

Targeting sugar moieties around cancer cells to kill tumors

Targeting sugar moieties around cancer cells to ki...

 63

Combination of RNA splicing factor and immunotherapy to treat neuroblastoma

Combination of RNA splicing factor and immunothera...

 48

Basal stem-like cells identified as origin of small cell lung cancer

Basal stem-like cells identified as origin of smal...

 70

How sugary drinks enhance colorectal cancer metastasis

How sugary drinks enhance colorectal cancer metast...

 134

Lysosome-to-mitochondria iron transfer regulate melanoma states

Lysosome-to-mitochondria iron transfer regulate me...

 112

Cancer cells can use backup routes to fuel their growth

Cancer cells can use backup routes to fuel their g...

 121

How small cell lung cancer hijacks neuronal synapses

How small cell lung cancer hijacks neuronal synapses

 66

How pediatric brain tumors grow

How pediatric brain tumors grow

 83

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

Tumors hijack macrophages for iron supply to promo...

 72

ADAR1 loss impairs glioblastoma tumor growth

ADAR1 loss impairs glioblastoma tumor growth

 70

Key mechanism for appetite and weight control

Key mechanism for appetite and weight control

 55

Macrophages protect insulin production in pancreas

Macrophages protect insulin production in pancreas

 62

Beta and delta cells communication to control glucose homeostasis in diabetes

Beta and delta cells communication to control gluc...

 79

Why obesity affects people differently

Why obesity affects people differently

 86

How exercise helps lose weight

How exercise helps lose weight

 64

Branched fatty acids metabolism in peroxisomes to control energy homeostasis

Branched fatty acids metabolism in peroxisomes to ...

 94

Genetic test predicts response to weight-loss drugs 

Genetic test predicts response to weight-loss drugs 

 63

A female-specific mechanism for energy expenditure in brown adipose tissue

A female-specific mechanism for energy expenditure...

 54

Neuritin 1 acts as a local metabolic regulator of brown adipose tissue

Neuritin 1 acts as a local metabolic regulator of ...

 84

How cilia regulate development of precursor cells in fat tissue

How cilia regulate development of precursor cells ...

 115

How weight loss drugs target the brain and pancreas

How weight loss drugs target the brain and pancreas

 146

Glucose transporter dysregulation in type 2-diabetes

Glucose transporter dysregulation in type 2-diabetes

 198

Epigenetic biomarkers predict cardiovascular risk for type 2 diabetes patients

Epigenetic biomarkers predict cardiovascular risk ...

 245

AI distinguishes glioblastoma from look-alike cancers during surgery

AI distinguishes glioblastoma from look-alike canc...

 7

DOLPHIN for exon-level single-cell RNA-seq data analysis

DOLPHIN for exon-level single-cell RNA-seq data an...

 43

Reading mice’s ‘thoughts’ from their facial expression

Reading mice’s ‘thoughts’ from their facial expres...

 33

AI used to create proteins that kill E. coli

AI used to create proteins that kill E. coli

 46

AI improves seizure prediction

AI improves seizure prediction

 42

AI model forecasts disease risk decades in advance

AI model forecasts disease risk decades in advance

 52

Differences in brain chemistry shape two common movement disorders

Differences in brain chemistry shape two common mo...

 62

AI to integrate bulk multi-omics data for precision oncology

AI to integrate bulk multi-omics data for precisio...

 84

AI reveals how protein modifications link mutations to disease

AI reveals how protein modifications link mutation...

 58

An open-source AI platform to democratize protein design

An open-source AI platform to democratize protein ...

 109

Proteomics and AI detects early signs of ALS in plasma years before symptoms appear

Proteomics and AI detects early signs of ALS in pl...

 96

Generative AI platform for mRNA therapeutics

Generative AI platform for mRNA therapeutics

 72

 Generative AI to design novel antibiotics

 Generative AI to design novel antibiotics

 64

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 52

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 35

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 59

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

 96

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

 60

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

 246

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

 226

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 324

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 455

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 317

Artificial sensing system using synthetic neurons

Artificial sensing system using synthetic neurons

 412

The nanoparticle-based vaccine against many variants of SARS-CoV-2

The nanoparticle-based vaccine against many varian...

 358

Nanoparticle-based itaconate treatment for atherosclerotic plaque resolution

Nanoparticle-based itaconate treatment for atheros...

 376

A cysteine-rich diet may promote regeneration of the intestinal lining

A cysteine-rich diet may promote regeneration of t...

 37

Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice

Stem cell transplant for stroke leads to brain cel...

 48

Stem cell models show epilepsy genes disrupt different brain regions

Stem cell models show epilepsy genes disrupt diffe...

 56

Ureteral organoid from pluripotent stem cells

Ureteral organoid from pluripotent stem cells

 42

Progenitor neighborhood signaling in neurogenesis

Progenitor neighborhood signaling in neurogenesis

 50

Evolutionary changes in the developing human intestine

Evolutionary changes in the developing human intes...

 224

Human kidney organoids from stem cells

Human kidney organoids from stem cells

 211

Human bone marrow stem cell metabolism altered by aging and cancer

Human bone marrow stem cell metabolism altered by ...

 253

Serine deprivation switches hair follicle stem cells into skin healers during injury

Serine deprivation switches hair follicle stem cel...

 230

Producing library of heterogeneous human neurons from stem cells

Producing library of heterogeneous human neurons f...

 280

Bile acid supplementation gives rise to grape-like liver organoid clusters

Bile acid supplementation gives rise to grape-like...

 234

Proliferating neural progenitors identified in the adult human hippocampus

Proliferating neural progenitors identified in the...

 220

Senescence-resistant human mesenchymal progenitor cells counter aging

Senescence-resistant human mesenchymal progenitor ...

 288

Gene therapy for alpha thalassemia major

Gene therapy for alpha thalassemia major

 69

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

 71

Genetic test predicts obesity in childhood

Genetic test predicts obesity in childhood

 197

Analysis of India's genetic diversity

Analysis of India's genetic diversity

 221

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 336

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 311

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 301

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 306

Genes for depression across ethnicities

Genes for depression across ethnicities

 333

Gene editing extends lifespan in mouse model of prion disease

Gene editing extends lifespan in mouse model of pr...

 282

Two new gene variants linked to epilepsy identified!

Two new gene variants linked to epilepsy identified!

 302

Dysregulation of mTOR signalling is a converging mechanism in lissencephaly

Dysregulation of mTOR signalling is a converging m...

 364

The role of rare germline structural variants in pediatric solid tumors

The role of rare germline structural variants in p...

 305

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

 42

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

 327

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 347

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 323

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 329

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 213

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 305

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 323

Role of ECM in brain memory

Role of ECM in brain memory

 307

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 316

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 315

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 313

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 197

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

 62

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

 122

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

 212

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

 277

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

 515

Key mechanism of brain repair in vascular dementia

Key mechanism of brain repair in vascular dementia

 217

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 250

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

 265

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 282

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 262

How a Y chromosome gene may shape the course of heart valve disease

How a Y chromosome gene may shape the course of he...

 382

Why babies recover, but adults scar, after heart damage

Why babies recover, but adults scar, after heart d...

 287

Testosterone increases damage following a heart attack

Testosterone increases damage following a heart at...

 279

Trophoblast differentiation in 3D bioprinted miniature placentas

Trophoblast differentiation in 3D bioprinted minia...

 37

Inflammatory diseases in the offspring from mothers food additive consumption during pregnancy

Inflammatory diseases in the offspring from mother...

 37

Two proteins found to be vital for male fertility

Two proteins found to be vital for male fertility

 69

Inflammation during pregnancy may prime offspring for anxiety

Inflammation during pregnancy may prime offspring ...

 80

Maternal gut microbiome composition may be linked to preterm births

Maternal gut microbiome composition may be linked ...

 74

New method to study embryonic implantation

New method to study embryonic implantation

 52

A keto diet might benefit females more than males

A keto diet might benefit females more than males

 82

Ultra-processed food consumption decreased sperm motility

Ultra-processed food consumption decreased sperm m...

 120

Estrogen inhibit ferroptosis and acute kidney injury

Estrogen inhibit ferroptosis and acute kidney injury

 183

Sex differences in tissue-specific immunity and immunology

Sex differences in tissue-specific immunity and im...

 244

New gene therapy for X-linked Rett syndrome in girls

New gene therapy for X-linked Rett syndrome in girls

 226

Cryo-EM structures reveal how GnRH activates its receptor

Cryo-EM structures reveal how GnRH activates its r...

 218

High blood pressure in pregnancy linked to increased risk of seizure in children

High blood pressure in pregnancy linked to increas...

 242

RNA splitting mechanism behind origin of Type V CRISPR systems

RNA splitting mechanism behind origin of Type V CR...

 20

 A ubiquitin precursor promotes stress resistance and longevity

 A ubiquitin precursor promotes stress resistance ...

 40

How a key enzyme shapes nucleus formation in cell division

How a key enzyme shapes nucleus formation in cell ...

 65

Lipids drive activation of the cellular degradation system LC3-associated phagocytosis

Lipids drive activation of the cellular degradatio...

 70

A molecular zipper and a DNA link team up to protect fertility

A molecular zipper and a DNA link team up to prote...

 39

Human genome rearrangement with programmable bridge recombinases

Human genome rearrangement with programmable bridg...

 55

Cellular quality control in humans decoded

Cellular quality control in humans decoded

 79

Macrophages swallow damaged mitochondria through microautophagy

Macrophages swallow damaged mitochondria through m...

 34

Dual nature of polyamines in longevity to cancer

Dual nature of polyamines in longevity to cancer

 49

Surprising role of Cas9 as a guardian of bacterial defense

Surprising role of Cas9 as a guardian of bacterial...

 42

Link between excessive alcohol and fatty liver disease

Link between excessive alcohol and fatty liver dis...

 86

Cells measure RNA tails with a molecular stopwatch

Cells measure RNA tails with a molecular stopwatch

 60

Newly discovered purging process in gastric cells

Newly discovered purging process in gastric cells

 57

How gut bacteria adapt to new environments

How gut bacteria adapt to new environments

 4

How antimicrobial peptides induce transient pores

How antimicrobial peptides induce transient pores

 52

How pathogens build protein machinery for survival in the gut

How pathogens build protein machinery for survival...

 28

Yeast in gut microbiome can worsen salmonella infection

Yeast in gut microbiome can worsen salmonella infe...

 40

Linking chronic sickle cell pain to gut microbial imbalance

Linking chronic sickle cell pain to gut microbial ...

 67

How a tick-borne virus enters human cells

How a tick-borne virus enters human cells

 33

New mechanisms for bacterial motility and DNA transfer between bacteria decoded

New mechanisms for bacterial motility and DNA tran...

 70

Mucus contains molecules that block Salmonella infection

Mucus contains molecules that block Salmonella inf...

 67

A simple CRISPR tuberculosis screening test

A simple CRISPR tuberculosis screening test

 52

Microbial piracy’ uncovers new way to fight drug-resistant infections

Microbial piracy’ uncovers new way to fight drug-r...

 43

A Velcro model for bacterium adhesion

A Velcro model for bacterium adhesion

 46

Can a healthy gut microbiome help prevent childhood stunting?

Can a healthy gut microbiome help prevent childhoo...

 38

Giant DNA discovered hiding in your mouth

Giant DNA discovered hiding in your mouth

 51

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

 27

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

 49

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

 123

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

 201

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

 232

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

 241

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 216

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 243

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 359

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 298

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 340

Leptin in neurodevelopment!

Leptin in neurodevelopment!

 320

Role of Integrator in early neural fate commitment

Role of Integrator in early neural fate commitment

 317

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

 7

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

 80

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

 302

How plants sense heat during the day

How plants sense heat during the day

 271

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 235

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 282

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 283

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 303

Key genes to fight against crop parasites identified!

Key genes to fight against crop parasites identified!

 277

CoQ10-producing rice with gene editing

CoQ10-producing rice with gene editing

 290

Bacteria used to amplify plant hormones

Bacteria used to amplify plant hormones

 285

Protein protects biological nitrogen fixation from oxidative stress

Protein protects biological nitrogen fixation from...

 337

Plant roots change their growth pattern during ‘puberty’

Plant roots change their growth pattern during ‘pu...

 318

‘Unconventional’ immune cells to tackle inflammation in the gut

‘Unconventional’ immune cells to tackle inflammati...

 37

Predicting if multiple sclerosis medication will be effective for patients

Predicting if multiple sclerosis medication will b...

 55

‘Creeping fat’ can worsen Crohn’s disease

‘Creeping fat’ can worsen Crohn’s disease

 54

Healthy telomeres key for cancer-fighting T cells

Healthy telomeres key for cancer-fighting T cells

 89

Cellular “toolkit” to reprogram immune cells for cancer therapy

Cellular “toolkit” to reprogram immune cells for c...

 102

New monoclonal antibody targets deadly sepsis

New monoclonal antibody targets deadly sepsis

 63

How cells in small intestine of people with coeliac disease communicate with one another

How cells in small intestine of people with coelia...

 145

Gut neurons help the body fight inflammation

Gut neurons help the body fight inflammation

 160

Breast milk maternal antibodies regulate early neonatal immune responses in mouse gut

Breast milk maternal antibodies regulate early neo...

 188

Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis

Cysteinyl leukotrienes stimulate gut absorption of...

 174

How the immune system fends off gut parasites

How the immune system fends off gut parasites

 278

How pH impacts the immune system

How pH impacts the immune system

 380

A deubiquitinase prevents ulcerative colitis by inhibiting microbiota-mediated STING activation

A deubiquitinase prevents ulcerative colitis by in...

 230

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 293

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 190

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 642

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 269

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 255

Printed skin to replace animal testing

Printed skin to replace animal testing

 279

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 254

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 264

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 280

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 293

Strategies to boost protein production from engineered cells

Strategies to boost protein production from engine...

 23

How unstructured protein segments regulate biological functions

How unstructured protein segments regulate biologi...

 35

A software to model tumor dynamics

A software to model tumor dynamics

 81

Human cilia study offers clues to childhood diseases

Human cilia study offers clues to childhood diseases

 38

Extreme lifespan multiomics

Extreme lifespan multiomics

 65

REPAIROME, a catalog of human DNA repair

REPAIROME, a catalog of human DNA repair

 77

New implant restores blood pressure balance after spinal cord injury

New implant restores blood pressure balance after ...

 41

Ultrasound enables deep brain stimulation in people without surgery

Ultrasound enables deep brain stimulation in peopl...

 48

The first structure of the complete botulinum neurotoxin complex

The first structure of the complete botulinum neur...

 60

Fat microscopy to image lipids in cells

Fat microscopy to image lipids in cells

 166

Brain-computer interface could decode inner speech in real time

Brain-computer interface could decode inner speech...

 66

PathoPlex maps the location of proteins inside cells

PathoPlex maps the location of proteins inside cells

 147

Cells change shape to deal with wounds

Cells change shape to deal with wounds

 134

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 23

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 231

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 226

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 232

How the brain regulates emotions

How the brain regulates emotions

 312

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 301

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 299

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 335

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 307

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 320

Link between dietary choices and brain health

Link between dietary choices and brain health

 299

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 204

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 354

Research

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Harnessing indole scaffolds to identify small- molecule IRE1α inhibitors modulating XBP1  mRNA splicing

Harnessing indole scaffolds to identify small- mol...

 6

Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics

Uncertainty-aware ensemble of foundation models di...

 7

Integrator 20th anniversary: a molecular machine indispensable in development and disease

Integrator 20th anniversary: a molecular machine i...

 20

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Adult hippocampal neurogenesis: New avenues for tr...

 39

Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria

Genetic controllers for enhancing the evolutionary...

 9

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 11

DOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction reads

DOLPHIN advances single-cell transcriptomics beyon...

 22

A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer

A combined enteric neuron-gastric tumor organoid r...

 23

Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment

Transient ligand contacts of the intrinsically dis...

 21

Embryonic signatures of intergenerational epigenetic inheritance across paternal environments and genetic backgrounds

Embryonic signatures of intergenerational epigenet...

 16

MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor

MRAP2 modifies the signaling and oligomerization s...

 30

Constructing artificial neurons with functional parameters comprehensively matching biological values

Constructing artificial neurons with functional pa...

 13

Intestinal CD4−CD8αβ−TCRαβ+ T cells function as tolerogenic antigen presenting cells in mice

Intestinal CD4−CD8αβ−TCRαβ+ T cells function as to...

 160

Harnessing indole scaffolds to identify small- molecule IRE1α inhibitors modulating XBP1  mRNA splicing

Harnessing indole scaffolds to identify small- mol...

 6

Integrator 20th anniversary: a molecular machine indispensable in development and disease

Integrator 20th anniversary: a molecular machine i...

 20

Adult hippocampal neurogenesis: New avenues for treatment of brain disorders

Adult hippocampal neurogenesis: New avenues for tr...

 39

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 11

A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer

A combined enteric neuron-gastric tumor organoid r...

 23

Transient ligand contacts of the intrinsically disordered N-terminus of neuropeptide Y2 receptor regulate arrestin-3 recruitment

Transient ligand contacts of the intrinsically dis...

 21

Embryonic signatures of intergenerational epigenetic inheritance across paternal environments and genetic backgrounds

Embryonic signatures of intergenerational epigenet...

 16

MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor

MRAP2 modifies the signaling and oligomerization s...

 30

Constructing artificial neurons with functional parameters comprehensively matching biological values

Constructing artificial neurons with functional pa...

 13

Intestinal CD4−CD8αβ−TCRαβ+ T cells function as tolerogenic antigen presenting cells in mice

Intestinal CD4−CD8αβ−TCRαβ+ T cells function as to...

 160

Optimality as a framework for understanding developmental robustness

Optimality as a framework for understanding develo...

 26

Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins

Inhibiting heme piracy by pathogenic Escherichia c...

 16

Rewiring of cortical glucose metabolism fuels human brain cancer growth

Rewiring of cortical glucose metabolism fuels huma...

 35

Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics

Uncertainty-aware ensemble of foundation models di...

 7

Genetic controllers for enhancing the evolutionary longevity of synthetic gene circuits in bacteria

Genetic controllers for enhancing the evolutionary...

 9

DOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction reads

DOLPHIN advances single-cell transcriptomics beyon...

 22

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

Human interpretable grammar encodes multicellular ...

 51

Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings

Ultra-high-density Neuropixels probes improve dete...

 28

Staying productive under pressure: systems evaluations of β-carotene production in Yarrowia lipolytica under continuous fermentation

Staying productive under pressure: systems evaluat...

 37

Matrix directs trophoblast differentiation in a bioprinted organoid model of early placental development

Matrix directs trophoblast differentiation in a bi...

 44

Sensitive pathogen DNA detection by a  multi-guide RNA Cas12a assay favoring trans- versus cis-cleavage

Sensitive pathogen DNA detection by a multi-guide...

 38

AVID mouse: A versatile platform for real-time, multiscale ATP imaging and spatial systems metabolism analysis in living mice

AVID mouse: A versatile platform for real-time, mu...

 71

AAV vectors: an emerging strategy for chronic pain management

AAV vectors: an emerging strategy for chronic pain...

 95

Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution

Absolute measurement of fast and slow neuronal sig...

 85

Flexynesis: A deep learning toolkit for bulk multi-omics data integration for precision oncology and beyond

Flexynesis: A deep learning toolkit for bulk multi...

 110

An ex vivo uterine system captures implantation, embryogenesis, and  trophoblast invasion via maternal- embryonic signaling

An ex vivo uterine system captures implantation, e...

 107

What is Asthma

What is Asthma

 42

Tuberculosis

Tuberculosis

 71

Anemia

Anemia

 113

What is Procrastination?

What is Procrastination?

 282

PARKINSON’S DISEASE

PARKINSON’S DISEASE

 1525

Anatomy of the Cerebellum

Anatomy of the Cerebellum

 1492

Anatomy of the Hippocampus

Anatomy of the Hippocampus

 1496

Cerebral Cortex

Cerebral Cortex

 1465

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

The Spinal Cord, Spinal Nerves, and Spinal Reflexes

 341

Protein Digestion and Absorption

Protein Digestion and Absorption

 709

AlphaFold: for Protein Structure Prediction

AlphaFold: for Protein Structure Prediction

 316

Protein structure, classification, functions, properties of proteins

Protein structure, classification, functions, prop...

 468

Post Translation Modification

Post Translation Modification

 456

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 33407

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 988

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 923

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 1799

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 307

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 298

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 319

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 165

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 295

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 326

School Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 262

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 261

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 291

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 449

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 360

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 308

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 313

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 290

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 331

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 281

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 304

APOE in Alzheimer’s

APOE in Alzheimer’s

 365

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 432

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 449

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 360

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 308

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 313

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 290

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 331

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 281

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 304

APOE in Alzheimer’s

APOE in Alzheimer’s

 365

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 432

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 298

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 330

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 262

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 262

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 261

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 291

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