Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

3342

Spread of pathology in neurodegenerative diseases: mechanisms and implications

Science Hangouts

Spread of pathology in neurodegenerative diseases: mechanisms and implications

27

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

Science Hangouts

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

29

Science News Highlights

Cholesterol homeostasis coordination by astrocytes to regulate Alzheimer’s pathology

News highlights

Cholesterol homeostasis coordination by astrocytes to regulate Alzheimer’s pathology

2

Mechanisms of axonopathy

News highlights

Mechanisms of axonopathy

4

Bile acids at the center of hepato-ocular crosstalk

News highlights

Bile acids at the center of hepato-ocular crosstalk

7

News

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

12

An aryl hydrocarbon receptor (AhR) linked to axon regeneration!

An aryl hydrocarbon receptor (AhR) linked to axon...

8

How key immune cells protect the prostate

How key immune cells protect the prostate

14

A missing link in how the brain regulates appetite

A missing link in how the brain regulates appetite

56

Composition of neuronal motor proteins regulates their cargo-specificity

Composition of neuronal motor proteins regulates t...

16

Nicotine Biosynthesis!

Nicotine Biosynthesis!

19

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

36

How multiple sclerosis kills neurons

How multiple sclerosis kills neurons

30

Pain-relieving drug with minimal addictive properties

Pain-relieving drug with minimal addictive properties

34

People use same neurons to see and imagine objects

People use same neurons to see and imagine objects

44

Blood-brain barrier regulators identified!

Blood-brain barrier regulators identified!

95

New acute myeloid leukemia “don’t eat me” signal discovered!

New acute myeloid leukemia “don’t eat me” signal d...

90

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

42

An aryl hydrocarbon receptor (AhR) linked to axon regeneration!

An aryl hydrocarbon receptor (AhR) linked to axon...

8

A missing link in how the brain regulates appetite

A missing link in how the brain regulates appetite

56

Composition of neuronal motor proteins regulates their cargo-specificity

Composition of neuronal motor proteins regulates t...

16

How multiple sclerosis kills neurons

How multiple sclerosis kills neurons

30

Pain-relieving drug with minimal addictive properties

Pain-relieving drug with minimal addictive properties

34

People use same neurons to see and imagine objects

People use same neurons to see and imagine objects

44

Blood-brain barrier regulators identified!

Blood-brain barrier regulators identified!

95

Spino-brain–spinal cord circuit that drives chronic pain identified!

Spino-brain–spinal cord circuit that drives chroni...

77

Tau mutation drives autophagy-lysosome dysfunction

Tau mutation drives autophagy-lysosome dysfunction

83

New optogenetic strategies to control neural pathways

New optogenetic strategies to control neural pathways

43

Anticancer antibodies can cause autoimmune brain disease

Anticancer antibodies can cause autoimmune brain d...

58

How aging changes the brains of mice similar to people

How aging changes the brains of mice similar to pe...

53

Molecular signatures of neurodegeneration using PanNDA

Molecular signatures of neurodegeneration using Pa...

59

New acute myeloid leukemia “don’t eat me” signal discovered!

New acute myeloid leukemia “don’t eat me” signal d...

90

Single nutrient fuels cancer-fighting power of T cells

Single nutrient fuels cancer-fighting power of T c...

35

Targeting cell surface protein uPAR with car t cell therapy to treat solid tumors and surroundings

Targeting cell surface protein uPAR with car t ce...

50

How inflammation may prime the gut for cancer

How inflammation may prime the gut for cancer

48

Restoring mitochondrial function in dendritic cells to treat cancer

Restoring mitochondrial function in dendritic cell...

68

An unexpected food source for tumors

An unexpected food source for tumors

71

Energy crisis drives T cells to exhaustion in tumors

Energy crisis drives T cells to exhaustion in tumors

84

Thymic health and cancer!

Thymic health and cancer!

56

Catch-bond engineering “turbocharge” T cells to attack prostate cancer

Catch-bond engineering “turbocharge” T cells to at...

57

How ageing promotes metastasis

How ageing promotes metastasis

65

Combination therapy to treat glioblastoma

Combination therapy to treat glioblastoma

79

How vitamin B2 could play a role in cancer therapies

How vitamin B2 could play a role in cancer therapies

87

Src kinase on the cell surface in cancer

Src kinase on the cell surface in cancer

89

Mechanism for body weight-reducing hormone identified!

Mechanism for body weight-reducing hormone identif...

42

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

42

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

50

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

59

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

76

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

167

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

81

Human islet cell electrical maturation

Human islet cell electrical maturation

81

Red blood cells soak up sugar at high altitude, protecting against diabetes

Red blood cells soak up sugar at high altitude, pr...

114

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

109

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

128

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

101

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

128

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

46

Gene signature predicting lung cancer recurrence

Gene signature predicting lung cancer recurrence

56

Bio-bank data analysis links genetics to disease risk and treatment response

Bio-bank data analysis links genetics to disease r...

56

Computational model measures telomere shortening from routine biopsies

Computational model measures telomere shortening f...

45

AI tool to predict heart diseases 15 years in advance

AI tool to predict heart diseases 15 years in advance

58

Artificial intelligence decodes tissue characteristics of type 2 diabetes

Artificial intelligence decodes tissue characteris...

64

Rapid Evolution of Complex Multi-mutant Proteins

Rapid Evolution of Complex Multi-mutant Proteins

95

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

102

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

82

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

121

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

136

Gene therapy for chronic pain?

Gene therapy for chronic pain?

108

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

113

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

109

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

72

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

102

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

157

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

137

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

142

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

181

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

159

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

188

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

206

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

182

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

372

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

341

What keeps vision cells alive?

What keeps vision cells alive?

43

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

39

A long-term and scalable system to record from neural organoids

A long-term and scalable system to record from neu...

49

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

74

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

84

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

93

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

224

How cell walls guide stem cells

How cell walls guide stem cells

88

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

117

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

108

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

118

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

97

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

100

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

43

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

64

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

65

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

62

How longevity is inherited across generations

How longevity is inherited across generations

121

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

77

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

109

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

89

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

78

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

114

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

95

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

98

Gene linked with risk of delirium

Gene linked with risk of delirium

100

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

59

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

97

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

107

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

137

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

432

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

446

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

431

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

469

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

321

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

406

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

498

Role of ECM in brain memory

Role of ECM in brain memory

407

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

417

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

92

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

63

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

80

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

73

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

82

A novel inflammatory function of platelets

A novel inflammatory function of platelets

93

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

97

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

111

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

101

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

139

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

134

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

116

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

148

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

43

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

63

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

64

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

89

sncRNAs in sperm aging

sncRNAs in sperm aging

65

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

124

How reproductive organs form

How reproductive organs form

101

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

121

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

111

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

150

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

194

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

150

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

115

RNA-guided CRISPR system activates gene expression

RNA-guided CRISPR system activates gene expression

66

Role of NAC complex in protein folding

Role of NAC complex in protein folding

39

Mechanism controlling cellular stress!

Mechanism controlling cellular stress!

56

Assembly of protein degradation complex

Assembly of protein degradation complex

42

Aging alters chromatin accessibility and nuclear mechanotransduction

Aging alters chromatin accessibility and nuclear m...

80

microRNA degradation via “two-factor authentication” system

microRNA degradation via “two-factor authenticatio...

49

Preventing pulmonary arterial hypertension

Preventing pulmonary arterial hypertension

40

Cartilage breakdown regulator identified!

Cartilage breakdown regulator identified!

52

RNA binding protein detects nonoptimal codon usage to regulate mRNA stability

RNA binding protein detects nonoptimal codon usage...

68

Mechanism of blood vessel signaling bias

Mechanism of blood vessel signaling bias

65

How flexible protein regions retain their function

How flexible protein regions retain their function

72

Complex DNA structures without hydrogen bonds

Complex DNA structures without hydrogen bonds

57

Optovolution of proteins!

Optovolution of proteins!

67

Gut–brain signalling in parasite infection

Gut–brain signalling in parasite infection

59

How bacteria drive chronic kidney disease progression

How bacteria drive chronic kidney disease progression

87

Enhancing gut-brain communication reversed cognitive decline in aging mice

Enhancing gut-brain communication reversed cogniti...

88

How deadly Marburg virus enters human cells

How deadly Marburg virus enters human cells

73

Microbiota derived nicotinic acid protects colon tissue

Microbiota derived nicotinic acid protects colon t...

73

Recent pandemic viruses jumped to humans without prior adaptation

Recent pandemic viruses jumped to humans without p...

57

How bacteria suppress immune defenses in stubborn wound infections

How bacteria suppress immune defenses in stubborn ...

64

Bacteria found in mouth and gut may help protect against severe peanut allergies

Bacteria found in mouth and gut may help protect a...

54

Molecular mechanism regulating bacterial cell division discovered

Molecular mechanism regulating bacterial cell divi...

67

Infant probiotic design from global microbiome atlas

Infant probiotic design from global microbiome atlas

58

Structures of hantavirus glycoprotein tetramers

Structures of hantavirus glycoprotein tetramers

61

Key protein that stops malaria parasite growth identified!

Key protein that stops malaria parasite growth ide...

64

Microbial interactions predict gut health

Microbial interactions predict gut health

67

When oxygen determines if a limb can regrow

When oxygen determines if a limb can regrow

12

Dysregulation of RNA editing in down syndrome

Dysregulation of RNA editing in down syndrome

34

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

41

A developmental atlas for genes and cells

A developmental atlas for genes and cells

64

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

85

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

71

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

155

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

140

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

147

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

165

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

242

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

295

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

330

Nicotine Biosynthesis!

Nicotine Biosynthesis!

19

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

47

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

65

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

51

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

59

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

120

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

212

How cucumbers got longer?

How cucumbers got longer?

171

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

123

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

130

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

126

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

196

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

399

How key immune cells protect the prostate

How key immune cells protect the prostate

14

Long-term inflammatory memory driver identified!

Long-term inflammatory memory driver identified!

59

Lung fibroblasts orchestrate inflammaging in old people

Lung fibroblasts orchestrate inflammaging in old ...

49

Vitamin D regulation of immune- gut microbiome interactions in IBD

Vitamin D regulation of immune- gut microbiome int...

59

Immune cells regulate eye pressure linked to glaucoma

Immune cells regulate eye pressure linked to glaucoma

59

How the fats we eat shape our ability to fight disease

How the fats we eat shape our ability to fight dis...

67

How immune cells extract nuclear DNA from dying cells

How immune cells extract nuclear DNA from dying cells

96

How the immune system recognizes viral RNA

How the immune system recognizes viral RNA

72

How dietary restriction rewires immunity to protect against infection

How dietary restriction rewires immunity to protec...

42

How chronic inflammation rewires macrophages

How chronic inflammation rewires macrophages

133

How a common immunosuppressive drug “ATG” injures liver blood vessels

How a common immunosuppressive drug “ATG” injures ...

62

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

69

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

91

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

32

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

41

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

120

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

398

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

293

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

756

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

380

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

375

Printed skin to replace animal testing

Printed skin to replace animal testing

373

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

350

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

368

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

396

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

393

The body’s internal clock can be determined from a hair sample

The body’s internal clock can be determined from a...

36

How the body senses cold

How the body senses cold

67

New computational biology for genome sequencing analysis

New computational biology for genome sequencing an...

60

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

75

Glycoprotein heterodimers on nanoparticles for hepatitis C virus vaccine design

Glycoprotein heterodimers on nanoparticles for hep...

59

Assay to analyze regulatory function and epigenomic modifications simultaneously

Assay to analyze regulatory function and epigenomi...

65

Peptide ligase–mediated display

Peptide ligase–mediated display

54

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

69

How bacteria bind to different types of cells

How bacteria bind to different types of cells

28

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

77

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

59

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

77

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

79

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

138

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

326

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

328

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

336

How the brain regulates emotions

How the brain regulates emotions

416

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

412

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

392

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

440

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

406

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

414

Link between dietary choices and brain health

Link between dietary choices and brain health

383

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

342

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

467

Research

Astrocytic AEBP1-NPAS3-LIPA pathway coordinates cholesterol homeostasis to regulate Alzheimer’s pathology

Astrocytic AEBP1-NPAS3-LIPA pathway coordinates ch...

13

AhR inhibition promotes axon regeneration via a stress–growth switch

AhR inhibition promotes axon regeneration via a st...

8

Axonopathy: mechanisms and potential therapeutic targets for neurodegenerative diseases

Axonopathy: mechanisms and potential therapeutic t...

20

Hepato-ocular crosstalk: Bile acids bridging pathogenesis and therapy

Hepato-ocular crosstalk: Bile acids bridging patho...

19

Complete biosynthesis of nicotine

Complete biosynthesis of nicotine

12

The impact of artificial sweeteners on bacterial physiology and the microbiome

The impact of artificial sweeteners on bacterial p...

22

Ferroptosis as an approach to leverage cancer metabolism

Ferroptosis as an approach to leverage cancer meta...

44

Reprogramming the mitochondrial–circadian energy code with incretins

Reprogramming the mitochondrial–circadian energy c...

891

Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair

Expansion of outer cortical CUX2 neurons requires ...

16

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

DNA damage burden causes selective CUX2 neuron los...

21

Understanding hypoparathyroidism as a disease of broad functional deficiency

Understanding hypoparathyroidism as a disease of b...

22

A μ-opioid receptor superagonist analgesic with minimal adverse effects

A μ-opioid receptor superagonist analgesic with mi...

15

LGR5: from stem cell marker to therapeutic target

LGR5: from stem cell marker to therapeutic target

27

Astrocytic AEBP1-NPAS3-LIPA pathway coordinates cholesterol homeostasis to regulate Alzheimer’s pathology

Astrocytic AEBP1-NPAS3-LIPA pathway coordinates ch...

13

AhR inhibition promotes axon regeneration via a stress–growth switch

AhR inhibition promotes axon regeneration via a st...

8

Axonopathy: mechanisms and potential therapeutic targets for neurodegenerative diseases

Axonopathy: mechanisms and potential therapeutic t...

20

Hepato-ocular crosstalk: Bile acids bridging pathogenesis and therapy

Hepato-ocular crosstalk: Bile acids bridging patho...

19

Complete biosynthesis of nicotine

Complete biosynthesis of nicotine

12

The impact of artificial sweeteners on bacterial physiology and the microbiome

The impact of artificial sweeteners on bacterial p...

22

Ferroptosis as an approach to leverage cancer metabolism

Ferroptosis as an approach to leverage cancer meta...

44

Reprogramming the mitochondrial–circadian energy code with incretins

Reprogramming the mitochondrial–circadian energy c...

891

Expansion of outer cortical CUX2 neurons requires adaptations for DNA repair

Expansion of outer cortical CUX2 neurons requires ...

16

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

DNA damage burden causes selective CUX2 neuron los...

21

Understanding hypoparathyroidism as a disease of broad functional deficiency

Understanding hypoparathyroidism as a disease of b...

22

A μ-opioid receptor superagonist analgesic with minimal adverse effects

A μ-opioid receptor superagonist analgesic with mi...

15

LGR5: from stem cell marker to therapeutic target

LGR5: from stem cell marker to therapeutic target

27

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

32

Whole-body molecular and cellular mapping of the laboratory mouse

Whole-body molecular and cellular mapping of the l...

34

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

Electrophysiological development and functional pl...

39

Tissue morphology predicts telomere shortening in human tissues

Tissue morphology predicts telomere shortening in ...

40

Metapipeline-DNA: A comprehensive germline and somatic genomics Nextflow pipeline

Metapipeline-DNA: A comprehensive germline and som...

40

Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain

Genetically encoded fluorescent reporters to visua...

54

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

78

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

80

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Simultaneous epigenomic profiling and regulatory a...

104

Single-cell and isoform-specific translational profiling of the mouse brain

Single-cell and isoform-specific translational pro...

87

Medaka: a novel model for analyzing genome– environment interactions

Medaka: a novel model for analyzing genome– enviro...

4626

Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization

Development of human induced pluripotent stem cell...

74

Challenges and opportunities in adapting high-throughput functional assays for in vivo neuroscience

Challenges and opportunities in adapting high-thro...

84

THALASSEMIA

THALASSEMIA

94

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

104

NMDA RECEPTORS

NMDA RECEPTORS

145

Neural Development

Neural Development

114

Transcription Factors

Transcription Factors

162

Interferons

89

RABIES

68

ANEMIA

60

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

79

Migraine

58

Dementia

102

Trisomy

73

Cystic Fibrosis

Cystic Fibrosis

84

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

88444

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1341

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1208

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

4252

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

409

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

395

HEAD AND NECK CANCER

HEAD AND NECK CANCER

423

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

261

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

389

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

430

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

377

Gestational diabetes therapeutics

Gestational diabetes therapeutics

364

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

408

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

575

Different types of Alzheimer's disease

Different types of Alzheimer's disease

495

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

435

Alzheimer’s therapeutics

Alzheimer’s therapeutics

450

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

460

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

470

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

409

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

417

APOE in Alzheimer’s

APOE in Alzheimer’s

506

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

559

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

575

Different types of Alzheimer's disease

Different types of Alzheimer's disease

495

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

435

Alzheimer’s therapeutics

Alzheimer’s therapeutics

450

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

460

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

470

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

409

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

417

APOE in Alzheimer’s

APOE in Alzheimer’s

506

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

559

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

407

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

457

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

387

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

377

Gestational diabetes therapeutics

Gestational diabetes therapeutics

364

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

408