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All Publications Protocols Presentations Posters
Monitoring the complexity and dynamics of mitochondrial translation

Monitoring the complexity and dynamics of mit...

 12

Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity

Environmental stiffness regulates neuronal ma...

 8

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

Mitochondrial ABHD11 inhibition drives sterol...

 12

Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor

Structure of the human astrovirus capsid spik...

 14

Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity

Environmental stiffness regulates neuronal ma...

 8

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

Mitochondrial ABHD11 inhibition drives sterol...

 12

Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor

Structure of the human astrovirus capsid spik...

 14

Integrated approaches for discovery and functional annotation of proteins of unknown function

Integrated approaches for discovery and funct...

 31

Monitoring the complexity and dynamics of mitochondrial translation

Monitoring the complexity and dynamics of mit...

 12

Micron-resolution fiber mapping in histology independent of sample preparation

Micron-resolution fiber mapping in histology ...

 22

Visual detection of seizures in mice using supervised machine learning

Visual detection of seizures in mice using su...

 28

Jaxley: differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics

Jaxley: differentiable simulation enables lar...

 45

Neural Transmission

Neural Transmission

 45

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-o...

 59

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

 257

Potassium Channels

Potassium Channels

 122

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGET...

 46588

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 1054

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 983

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 2424

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Science Hangouts

Atomic Force Microscopy: Towards Medical Applications.
Science Hangouts

Atomic Force Microscopy: Towards Medical Applications.

 154

A Novel Atypical Sperm Centriole is Functional During Fertilization
Science Hangouts

A Novel Atypical Sperm Centriole is Functional During Fertilization

 150

GABAergic signaling at the Axon Initial Segment
Science Hangouts

GABAergic signaling at the Axon Initial Segment

 162

The Regulation of Cancer Cell Death and Metabolism by Extracellular Matrix Attachment
Science Hangouts

The Regulation of Cancer Cell Death and Metabolism by Extracellular Matrix Attachment

 930

Salt, liver, ketones and hypertension- What are the links?
Science Hangouts

Salt, liver, ketones and hypertension- What are the links?

 81

Can Time Restricted Eating be a Foundation for Longevity?
Science Hangouts

Can Time Restricted Eating be a Foundation for Longevity?

 101

Science News Highlights

Mitochondrial translation monitoring
News highlights

Mitochondrial translation monitoring

 10

Characterizing proteins of unknown function
News highlights

Characterizing proteins of unknown function

 13

Body weight reduction by analog of prolactin-releasing peptide
News highlights

Body weight reduction by analog of prolactin-releasing...

 14

News

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Environmental stiffness regulates neuronal maturation

Environmental stiffness regulates neuronal maturation

 11

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

 29

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

 24

 How human astroviruses bind to humans cells?

 How human astroviruses bind to humans cells?

 18

Biliverdin reductase A (BVRA) protects brain from oxidative stress damage

Biliverdin reductase A (BVRA) protects brain from ...

 31

Eliminating cancer by harnessing tumor cell signaling

Eliminating cancer by harnessing tumor cell signaling

 43

Free radicals in the brain that may fuel dementia

Free radicals in the brain that may fuel dementia

 59

Leukemia mutations in nuclear droplets!

Leukemia mutations in nuclear droplets!

 29

AI Uncovers Genetic Architecture of the Human Corpus Callosum

AI Uncovers Genetic Architecture of the Human Corp...

 62

Cryo-EM structure of yellow fever virus

Cryo-EM structure of yellow fever virus

 24

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

 69

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

 32

Intestinal enzyme FMO-2 regulates behavior

Intestinal enzyme FMO-2 regulates behavior

 84

Environmental stiffness regulates neuronal maturation

Environmental stiffness regulates neuronal maturation

 11

Biliverdin reductase A (BVRA) protects brain from oxidative stress damage

Biliverdin reductase A (BVRA) protects brain from ...

 31

Free radicals in the brain that may fuel dementia

Free radicals in the brain that may fuel dementia

 59

Intestinal enzyme FMO-2 regulates behavior

Intestinal enzyme FMO-2 regulates behavior

 84

Microglia expressing lymphoid genes are neuroprotective

Microglia expressing lymphoid genes are neuroprote...

 35

Where language comes from?

Where language comes from?

 27

A new on-switch for pain signaling pathway

A new on-switch for pain signaling pathway

 53

Targeting brain immune cells could restore Alzheimer’s-related lipid imbalance

Targeting brain immune cells could restore Alzheim...

 61

How hunger tunes the brain

How hunger tunes the brain

 61

Cortical GABAergic projection neurons are implicated in schizophrenia

Cortical GABAergic projection neurons are implicat...

 110

Brain without sleep!

Brain without sleep!

 54

The link between the gut microbiome and autism is not backed by science!

The link between the gut microbiome and autism is ...

 56

Alleviating Parkinson’s motor deficits by bioengineered gut bacterium

Alleviating Parkinson’s motor deficits by bioengin...

 153

Eliminating cancer by harnessing tumor cell signaling

Eliminating cancer by harnessing tumor cell signaling

 43

Leukemia mutations in nuclear droplets!

Leukemia mutations in nuclear droplets!

 29

 Blocking key protein triggers cancer cell self-destruction

 Blocking key protein triggers cancer cell self-de...

 41

Promising drug for aggressive breast cancer

Promising drug for aggressive breast cancer

 52

How controlling sunburn-triggered inflammation may prevent skin cancer

How controlling sunburn-triggered inflammation may...

 61

Controlling cancer drug response by regulating purine biosynthesis

Controlling cancer drug response by regulating pur...

 54

A novel mechanism behind breast cancer chemoresistance discovered

A novel mechanism behind breast cancer chemoresist...

 61

RNA mediated lipid droplet gene hub for cancer progression

RNA mediated lipid droplet gene hub for cancer pro...

 56

Acetate from tumor-associated macrophages fuels liver cancer metastasis

Acetate from tumor-associated macrophages fuels li...

 115

Pan-immunotherapy biomarker for treatment monitoring

Pan-immunotherapy biomarker for treatment monitoring

 66

Loss of transcription factor suppresses metastasis of mammary tumors

Loss of transcription factor suppresses metastasis...

 66

Craters on surface of melanoma cells found to serve as sites for tumor killing

Craters on surface of melanoma cells found to serv...

 68

Targeted NanoSeq tool reveals hidden mutations that can drive cancer

Targeted NanoSeq tool reveals hidden mutations tha...

 62

Aged blood vessel cells drive metabolic diseases

Aged blood vessel cells drive metabolic diseases

 70

Genes associated with obesity shared across ancestries

Genes associated with obesity shared across ancest...

 57

A muscle specific protein reduces high ketone levels in diabetic patients

A muscle specific protein reduces high ketone leve...

 44

Genetic variants controlling body weight

Genetic variants controlling body weight

 76

Role of nuclear hormone-sensitive lipase (HSL) in lipid metabolism

Role of nuclear hormone-sensitive lipase (HSL) in ...

 57

Glycation-lowering compounds curb hunger, lower insulin resistance and extend lifespan 

Glycation-lowering compounds curb hunger, lower in...

 197

Gene converts insulin-producing cells into blood-sugar boosters

Gene converts insulin-producing cells into blood-s...

 116

Key mechanism for appetite and weight control

Key mechanism for appetite and weight control

 102

Macrophages protect insulin production in pancreas

Macrophages protect insulin production in pancreas

 102

Beta and delta cells communication to control glucose homeostasis in diabetes

Beta and delta cells communication to control gluc...

 128

Why obesity affects people differently

Why obesity affects people differently

 125

How exercise helps lose weight

How exercise helps lose weight

 101

Branched fatty acids metabolism in peroxisomes to control energy homeostasis

Branched fatty acids metabolism in peroxisomes to ...

 134

AI Uncovers Genetic Architecture of the Human Corpus Callosum

AI Uncovers Genetic Architecture of the Human Corp...

 62

AI can speed antibody design

AI can speed antibody design

 70

AI generative models reveal the cortical representation of dancing

AI generative models reveal the cortical represent...

 26

AI based biophysical models of neural dynamics

AI based biophysical models of neural dynamics

 49

Human Replication Protein A complex is Essential for Telomere Maintenance

Human Replication Protein A complex is Essential f...

 40

Amino acids play a key role in  brain's G protein signaling

Amino acids play a key role in brain's G protein ...

 89

AI-tool for 3D cell analysis

AI-tool for 3D cell analysis

 76

Neural mechanisms behind cooperation

Neural mechanisms behind cooperation

 89

A human pan-disease blood atlas of the circulating proteome

A human pan-disease blood atlas of the circulating...

 293

A language model for enhanced lasso peptide property prediction

A language model for enhanced lasso peptide proper...

 60

AI model to build one of the most detailed mouse brain maps

AI model to build one of the most detailed mouse b...

 70

AI distinguishes glioblastoma from look-alike cancers during surgery

AI distinguishes glioblastoma from look-alike canc...

 61

DOLPHIN for exon-level single-cell RNA-seq data analysis

DOLPHIN for exon-level single-cell RNA-seq data an...

 88

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

 59

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

 32

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

 63

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

 94

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

 68

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

 98

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

 132

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

 94

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

 276

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

 259

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

 358

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

 494

Microfluidic protocol to extract and purify DNA

Microfluidic protocol to extract and purify DNA

 350

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

 52

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

 48

How hair stem cells under stress make decisions to graying or melanoma

How hair stem cells under stress make decisions to...

 63

A cysteine-rich diet may promote regeneration of the intestinal lining

A cysteine-rich diet may promote regeneration of t...

 69

Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice

Stem cell transplant for stroke leads to brain cel...

 79

Stem cell models show epilepsy genes disrupt different brain regions

Stem cell models show epilepsy genes disrupt diffe...

 83

Ureteral organoid from pluripotent stem cells

Ureteral organoid from pluripotent stem cells

 73

Progenitor neighborhood signaling in neurogenesis

Progenitor neighborhood signaling in neurogenesis

 73

Evolutionary changes in the developing human intestine

Evolutionary changes in the developing human intes...

 251

Human kidney organoids from stem cells

Human kidney organoids from stem cells

 246

Human bone marrow stem cell metabolism altered by aging and cancer

Human bone marrow stem cell metabolism altered by ...

 275

Serine deprivation switches hair follicle stem cells into skin healers during injury

Serine deprivation switches hair follicle stem cel...

 256

Producing library of heterogeneous human neurons from stem cells

Producing library of heterogeneous human neurons f...

 308

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

 55

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

 49

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

 71

A genome-to-proteome map

A genome-to-proteome map

 79

Why naked mole-rats live longer

Why naked mole-rats live longer

 50

Gene therapy for alpha thalassemia major

Gene therapy for alpha thalassemia major

 94

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

 106

Genetic test predicts obesity in childhood

Genetic test predicts obesity in childhood

 226

Analysis of India's genetic diversity

Analysis of India's genetic diversity

 249

ITSN1 gene linked to substantial risk of Parkinson’s disease

ITSN1 gene linked to substantial risk of Parkinson...

 360

Disordered renal metabolism in myotonic dystrophy type 1

Disordered renal metabolism in myotonic dystrophy ...

 336

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

Gene ‘silencer’ in junk DNA prevents fatal neurolo...

 331

The role of moms X chromosome in cognition and aging of daughter

The role of moms X chromosome in cognition and agi...

 332

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

 65

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

 357

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

 374

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

 351

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

 361

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 244

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

 332

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

 356

Role of ECM in brain memory

Role of ECM in brain memory

 335

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

 345

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

 342

Cell vulnerability 'fingerprint' related to Parkinson's identified!

Cell vulnerability 'fingerprint' related to Parkin...

 340

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

 229

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

 24

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

 35

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

 49

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

 87

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

 151

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

 235

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

 301

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

 540

Key mechanism of brain repair in vascular dementia

Key mechanism of brain repair in vascular dementia

 245

Fixing cholesterol metabolism problem to prevent blindness

Fixing cholesterol metabolism problem to prevent b...

 279

Similarities between atherosclerotic blood vessels and tumor development

Similarities between atherosclerotic blood vessels...

 296

TMEM65 regulates mitochondrial calcium efflux

TMEM65 regulates mitochondrial calcium efflux

 309

Inhibition of ceramide synthesis contributes to cardiometabolic diseases

Inhibition of ceramide synthesis contributes to ca...

 287

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

 32

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

 59

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

 113

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

 77

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

 51

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

 54

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

 63

Functional eggs from human skin cells

Functional eggs from human skin cells

 64

Sperm microRNAs regulate paternal transmission of exercise capacity

Sperm microRNAs regulate paternal transmission of ...

 66

How sperm achieves energy demands for fertilization

How sperm achieves energy demands for fertilization

 81

Why does female fertility decline with age?

Why does female fertility decline with age?

 55

Trophoblast differentiation in 3D bioprinted miniature placentas

Trophoblast differentiation in 3D bioprinted minia...

 63

Inflammatory diseases in the offspring from mothers food additive consumption during pregnancy

Inflammatory diseases in the offspring from mother...

 61

Protein droplets in the nucleus guard against cancer 

Protein droplets in the nucleus guard against cancer 

 31

A ‘hidden pocket’ to target nuclear receptors

A ‘hidden pocket’ to target nuclear receptors

 60

Direct targeting and regulation of RNA polymerase II by cell signaling kinases

Direct targeting and regulation of RNA polymerase ...

 73

Saving cells from the brink of death

Saving cells from the brink of death

 74

 ‘Traffic controller’ protein protects DNA, and may kill cancer cells

 ‘Traffic controller’ protein protects DNA, and ma...

 40

Self-cleavage as built-in quality control

Self-cleavage as built-in quality control

 70

Protein condensates determine a cell’s fate

Protein condensates determine a cell’s fate

 98

RNA splitting mechanism behind origin of Type V CRISPR systems

RNA splitting mechanism behind origin of Type V CR...

 52

 A ubiquitin precursor promotes stress resistance and longevity

 A ubiquitin precursor promotes stress resistance ...

 68

How a key enzyme shapes nucleus formation in cell division

How a key enzyme shapes nucleus formation in cell ...

 92

Lipids drive activation of the cellular degradation system LC3-associated phagocytosis

Lipids drive activation of the cellular degradatio...

 95

A molecular zipper and a DNA link team up to protect fertility

A molecular zipper and a DNA link team up to prote...

 71

Human genome rearrangement with programmable bridge recombinases

Human genome rearrangement with programmable bridg...

 89

 How human astroviruses bind to humans cells?

 How human astroviruses bind to humans cells?

 18

Rebalancing lung repair with immune damage is key to surviving severe influenza

Rebalancing lung repair with immune damage is key ...

 30

Toxic gut bacteria may drive ulcerative colitis 

Toxic gut bacteria may drive ulcerative colitis 

 45

Missing nutrient in HIV mothers milk pose health challenges in children 

Missing nutrient in HIV mothers milk pose health c...

 28

How bacteria that cause inflammatory colitis outmaneuver our body’s defenses

How bacteria that cause inflammatory colitis outma...

 36

New mechanism for tick born viral entry into human cells

New mechanism for tick born viral entry into human...

 38

Serotonin producing human microbiota identified!

Serotonin producing human microbiota identified!

 769

Vitamin D levels fell during COVID-19 pandemic

Vitamin D levels fell during COVID-19 pandemic

 79

HIV-1 integrase structure revealed!

HIV-1 integrase structure revealed!

 83

Dangerous E. coli strain blocks gut’s defense mechanism to spread infection

Dangerous E. coli strain blocks gut’s defense mech...

 51

Discovery of hundreds of new human gut viruses

Discovery of hundreds of new human gut viruses

 147

Linking stable gut bacteria to healthy childhood growth

Linking stable gut bacteria to healthy childhood g...

 59

How retroviruses escape endosome to infect cells

How retroviruses escape endosome to infect cells

 42

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

 69

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

 66

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

 66

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

 71

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

 148

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

 225

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

 259

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

 264

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

 241

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

 264

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

 381

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

 326

Mechanism to bring newborn neurons out of the neuronal nest

Mechanism to bring newborn neurons out of the neur...

 370

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

 28

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

 125

How cucumbers got longer?

How cucumbers got longer?

 85

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

 42

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

 55

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

 54

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

 111

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

 326

How plants sense heat during the day

How plants sense heat during the day

 297

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

 260

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

 307

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

 315

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

 336

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

 29

Oxygen deprivation drives dysfunctional neutrophil immunity

Oxygen deprivation drives dysfunctional neutrophil...

 71

Psoriasis-linked gene mutation also impacts gut health

Psoriasis-linked gene mutation also impacts gut he...

 64

‘Unconventional’ immune cells to tackle inflammation in the gut

‘Unconventional’ immune cells to tackle inflammati...

 72

Predicting if multiple sclerosis medication will be effective for patients

Predicting if multiple sclerosis medication will b...

 81

‘Creeping fat’ can worsen Crohn’s disease

‘Creeping fat’ can worsen Crohn’s disease

 77

Healthy telomeres key for cancer-fighting T cells

Healthy telomeres key for cancer-fighting T cells

 122

Cellular “toolkit” to reprogram immune cells for cancer therapy

Cellular “toolkit” to reprogram immune cells for c...

 129

New monoclonal antibody targets deadly sepsis

New monoclonal antibody targets deadly sepsis

 90

How cells in small intestine of people with coeliac disease communicate with one another

How cells in small intestine of people with coelia...

 168

Gut neurons help the body fight inflammation

Gut neurons help the body fight inflammation

 184

Breast milk maternal antibodies regulate early neonatal immune responses in mouse gut

Breast milk maternal antibodies regulate early neo...

 212

Cysteinyl leukotrienes stimulate gut absorption of food allergens to promote anaphylaxis

Cysteinyl leukotrienes stimulate gut absorption of...

 197

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

 319

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

 218

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

 669

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

 294

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

 285

Printed skin to replace animal testing

Printed skin to replace animal testing

 300

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

 274

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

 293

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

 309

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

 333

Cryo-EM structure of yellow fever virus

Cryo-EM structure of yellow fever virus

 24

A new atlas of the human brain

A new atlas of the human brain

 46

Simple method for viewing microscopic fibers

Simple method for viewing microscopic fibers

 32

New CRISPR platform to expose concealed metastasis regulators

New CRISPR platform to expose concealed metastasis...

 58

Imaging microvasculature of an entire organ using ultrasound in 4D

Imaging microvasculature of an entire organ using ...

 30

New dry macular degeneration treatment 

New dry macular degeneration treatment 

 18

Spatial biology to visualize chemical signals of individual cells

Spatial biology to visualize chemical signals of i...

 34

Identification of antimalarial target binding partner

Identification of antimalarial target binding partner

 54

Algorithm maps genetic connection between Alzheimer’s and specific neurons

Algorithm maps genetic connection between Alzheime...

 55

"A DNA search engine"

"A DNA search engine"

 64

Unlocking new patterns of protein behavior in cell membranes

Unlocking new patterns of protein behavior in cell...

 63

A chemical epigenetic tool to probe site-specific DNA-binding protein complexes

A chemical epigenetic tool to probe site-specific ...

 65

Simultaneous synthesis of all 21 types of tRNA in vitro

Simultaneous synthesis of all 21 types of tRNA in ...

 98

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

 61

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

 257

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

 247

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

 260

How the brain regulates emotions

How the brain regulates emotions

 341

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

 331

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

 322

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

 369

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

 336

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

 348

Link between dietary choices and brain health

Link between dietary choices and brain health

 323

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

 240

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

 381

Research

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    • Publications
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Monitoring the complexity and dynamics of mitochondrial translation

Monitoring the complexity and dynamics of mitochon...

 12

Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity

Environmental stiffness regulates neuronal maturat...

 8

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

Mitochondrial ABHD11 inhibition drives sterol meta...

 12

Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor

Structure of the human astrovirus capsid spike in ...

 14

Integrated approaches for discovery and functional annotation of proteins of unknown function

Integrated approaches for discovery and functional...

 31

Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

Analog of prolactin-releasing peptide reduces body...

 23

Biliverdin reductase A is a major determinant of protective NRF2 signaling

Biliverdin reductase A is a major determinant of p...

 19

Restoration of cGAS in cancer cells promotes antitumor immunity via transfer of cancer cell–generated cGAMP

Restoration of cGAS in cancer cells promotes antit...

 21

Predicting healthspan and disease risks through biological age

Predicting healthspan and disease risks through bi...

 26

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

Mitochondrial complex III-derived ROS amplify immu...

 22

The Genetic Architecture of the Human Corpus Callosum and its Subregions

The Genetic Architecture of the Human Corpus Callo...

 13

A single residue in the yellow fever virus envelope protein modulates virion architecture and antigenicity

A single residue in the yellow fever virus envelop...

 16

Neural hijacking in cancer metabolism: from nutrients to organelles

Neural hijacking in cancer metabolism: from nutrie...

 40

Environmental stiffness regulates neuronal maturation via Piezo1-mediated transthyretin activity

Environmental stiffness regulates neuronal maturat...

 8

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function

Mitochondrial ABHD11 inhibition drives sterol meta...

 12

Structure of the human astrovirus capsid spike in complex with the neonatal Fc receptor

Structure of the human astrovirus capsid spike in ...

 14

Integrated approaches for discovery and functional annotation of proteins of unknown function

Integrated approaches for discovery and functional...

 31

Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia

Analog of prolactin-releasing peptide reduces body...

 23

Biliverdin reductase A is a major determinant of protective NRF2 signaling

Biliverdin reductase A is a major determinant of p...

 19

Restoration of cGAS in cancer cells promotes antitumor immunity via transfer of cancer cell–generated cGAMP

Restoration of cGAS in cancer cells promotes antit...

 21

Predicting healthspan and disease risks through biological age

Predicting healthspan and disease risks through bi...

 26

Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

Mitochondrial complex III-derived ROS amplify immu...

 22

The Genetic Architecture of the Human Corpus Callosum and its Subregions

The Genetic Architecture of the Human Corpus Callo...

 13

A single residue in the yellow fever virus envelope protein modulates virion architecture and antigenicity

A single residue in the yellow fever virus envelop...

 16

Neural hijacking in cancer metabolism: from nutrients to organelles

Neural hijacking in cancer metabolism: from nutrie...

 40

Sodium's role and therapeutic targeting in cancer

Sodium's role and therapeutic targeting in cancer

 80

Monitoring the complexity and dynamics of mitochondrial translation

Monitoring the complexity and dynamics of mitochon...

 12

Micron-resolution fiber mapping in histology independent of sample preparation

Micron-resolution fiber mapping in histology indep...

 22

Visual detection of seizures in mice using supervised machine learning

Visual detection of seizures in mice using supervi...

 28

Jaxley: differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics

Jaxley: differentiable simulation enables large-sc...

 45

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases

The Neurolipid Atlas: a lipidomics resource for ne...

 93

Spatial biology using single-cell mass spectrometry imaging and integrated microscopy

Spatial biology using single-cell mass spectrometr...

 45

Experimental tools and emerging principles of organellar mechanotransduction

Experimental tools and emerging principles of orga...

 58

HCS-3DX, a next-generation AI-driven automated 3D-oid high-content screening system

HCS-3DX, a next-generation AI-driven automated 3D-...

 45

Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution

Sequencing-free whole-genome spatial transcriptomi...

 62

Efficient and accurate search in petabase-scale sequence repositories

Efficient and accurate search in petabase-scale se...

 81

AIstain: Enhancing microglial phagocytosis analysis through deep learning

AIstain: Enhancing microglial phagocytosis analysi...

 66

Simultaneous in vitro expression of minimal 21 transfer RNAs by tRNA array method

Simultaneous in vitro expression of minimal 21 tra...

 80

Uncertainty-aware ensemble of foundation models differentiates glioblastoma from its mimics

Uncertainty-aware ensemble of foundation models di...

 47

Neural Transmission

Neural Transmission

 45

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

 59

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

 257

Potassium Channels

Potassium Channels

 122

Calcium channels physiology and Therapeutics uses

Calcium channels physiology and Therapeutics uses

 164

Cell Signaling and Communication between Cells

Cell Signaling and Communication between Cells

 406

Humoral Immunity

Humoral Immunity

 84

Cell Mediated Immunity

Cell Mediated Immunity

 239

Telomere

Telomere

 91

What is Asthma

What is Asthma

 80

Tuberculosis

Tuberculosis

 97

Anemia

Anemia

 141

What is Procrastination?

What is Procrastination?

 314

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

 46588

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

 1054

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

 983

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

 2424

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

 333

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

 324

HEAD AND NECK CANCER

HEAD AND NECK CANCER

 342

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

 189

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

 315

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

 351

School Science

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Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 296

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 290

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 318

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 484

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 387

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 339

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 344

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 323

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 361

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 307

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 333

APOE in Alzheimer’s

APOE in Alzheimer’s

 389

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 461

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

 484

Different types of Alzheimer's disease

Different types of Alzheimer's disease

 387

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

 339

Alzheimer’s therapeutics

Alzheimer’s therapeutics

 344

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

 323

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

 361

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

 307

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

 333

APOE in Alzheimer’s

APOE in Alzheimer’s

 389

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

 461

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

 324

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

 356

Presenilin (PSEN)  in Alzheimer’s

Presenilin (PSEN)  in Alzheimer’s

 285

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

 296

Gestational diabetes therapeutics

Gestational diabetes therapeutics

 290

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

 318

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