Index - Sciencemission

Science Hangouts

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

Science Hangouts

First clinical trial of NAD+ Boosting Vitamin, Nicotinamide Riboside (NR)

739

Modeling neurodevelomental disorders with stem cells and brain organoids

Science Hangouts

Modeling neurodevelomental disorders with stem cells and brain organoids

47

Zika virus and maternal fetal transmission

Science Hangouts

Zika virus and maternal fetal transmission

48

Assembling and disassembling the nervous system

Science Hangouts

Assembling and disassembling the nervous system

50

Science News Highlights

Mapping clinical CAR-T cells using scRNA-seq

News highlights

Mapping clinical CAR-T cells using scRNA-seq

3

Circadian clock role in transcription-coupled DSB repair

News highlights

Circadian clock role in transcription-coupled DSB repair

4

mRNA vaccines for orthoflaviviruses

News highlights

mRNA vaccines for orthoflaviviruses

6

News

New treatment for drug-resistant fungal infections

New treatment for drug-resistant fungal infections

1

Peripheral neuropathy protection by mitochondrial transfer from glia to neurons

Peripheral neuropathy protection by mitochondrial ...

15

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

19

Microbes in breast milk help populate infant gut microbiomes

Microbes in breast milk help populate infant gut m...

15

How peripheral nerve injury causes neuropathic pain

How peripheral nerve injury causes neuropathic pain

24

Cas12a3 cleaves tRNA tails!

Cas12a3 cleaves tRNA tails!

21

Hydrogen sulfide producing enzyme is a therapeutic target for Alzheimer’s disease

Hydrogen sulfide producing enzyme is a therapeutic...

26

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

37

Inflammation fuels one of the most aggressive forms of cancer

Inflammation fuels one of the most aggressive form...

66

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

27

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

26

Virus-drug structure, interaction in real time

Virus-drug structure, interaction in real time

35

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

32

Peripheral neuropathy protection by mitochondrial transfer from glia to neurons

Peripheral neuropathy protection by mitochondrial ...

15

How peripheral nerve injury causes neuropathic pain

How peripheral nerve injury causes neuropathic pain

24

Hydrogen sulfide producing enzyme is a therapeutic target for Alzheimer’s disease

Hydrogen sulfide producing enzyme is a therapeutic...

26

Neural circuitry in bone and key signals for bone repair

Neural circuitry in bone and key signals for bone ...

36

How the brain creates facial expressions

How the brain creates facial expressions

33

Homer1 gene improves focus!

Homer1 gene improves focus!

37

Regulating tryptophan catabolism to control neurodegeneration

Regulating tryptophan catabolism to control neurod...

90

How stroke risk gene maintains brain small blood vessel function

How stroke risk gene maintains brain small blood v...

27

Stimulant ADHD medications work differently than thought

Stimulant ADHD medications work differently than t...

428

Alzheimer’s disease reversal by restoring the brain’s energy balance

Alzheimer’s disease reversal by restoring the brai...

79

Exercise enhances hormone shuttling across blood brain barrier

Exercise enhances hormone shuttling across blood b...

109

How energy, immune and vascular changes linked to ME/CFS

How energy, immune and vascular changes linked to ...

107

How the brain measures distance

How the brain measures distance

36

Inflammation fuels one of the most aggressive forms of cancer

Inflammation fuels one of the most aggressive form...

66

Origin cells for malignant brain tumor identified

Origin cells for malignant brain tumor identified

42

High-fat diets make liver cells more likely to become cancerous

High-fat diets make liver cells more likely to bec...

145

Opposing functions of distinct regulatory T cell subsets in colorectal cancer

Opposing functions of distinct regulatory T cell s...

46

How glioblastoma tumors dodge chemotherapy

How glioblastoma tumors dodge chemotherapy

42

Targeting B cells enhances STING agonism in liver cancer

Targeting B cells enhances STING agonism in liver ...

59

How cancer escapes cell death and cell division arrest

How cancer escapes cell death and cell division ar...

59

How cancer cells survive immune attack

How cancer cells survive immune attack

104

Role of mobile DNA elements in lung cancer progression

Role of mobile DNA elements in lung cancer progres...

52

How microtubules take part in cellular signal processing

How microtubules take part in cellular signal proc...

80

Key driver of treatment-resistant cancer uncovered!

Key driver of treatment-resistant cancer uncovered!

82

Regulation of cellular aging!

Regulation of cellular aging!

91

How tumors thrive in acidic, low-oxygen environments?

How tumors thrive in acidic, low-oxygen environments?

98

The mechanism behind quality control of insulin in the endoplasmic reticulum

The mechanism behind quality control of insulin in...

27

A microbial molecule disarms inflammation and protects against diabetes

A microbial molecule disarms inflammation and prot...

142

How the Immune System Stalls Weight Loss

How the Immune System Stalls Weight Loss

130

Metabolites produced in the intestine play a central role in controlling obesity and diabetes

Metabolites produced in the intestine play a centr...

284

How statins harm muscles—and how to stop it

How statins harm muscles—and how to stop it

138

Mitochondrial ketone body oxidation impaired in diabetes & liver disease

Mitochondrial ketone body oxidation impaired in di...

107

Sons of mothers with type 1 diabetes show early signs of vascular dysfunction

Sons of mothers with type 1 diabetes show early si...

67

Aged blood vessel cells drive metabolic diseases

Aged blood vessel cells drive metabolic diseases

110

Genes associated with obesity shared across ancestries

Genes associated with obesity shared across ancest...

97

A muscle specific protein reduces high ketone levels in diabetic patients

A muscle specific protein reduces high ketone leve...

83

Genetic variants controlling body weight

Genetic variants controlling body weight

115

Role of nuclear hormone-sensitive lipase (HSL) in lipid metabolism

Role of nuclear hormone-sensitive lipase (HSL) in ...

100

Glycation-lowering compounds curb hunger, lower insulin resistance and extend lifespan

Glycation-lowering compounds curb hunger, lower in...

241

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

37

AI identified statins and phenothiazines for neuroblastoma treatment

AI identified statins and phenothiazines for neuro...

26

Mapping drug binding in individual cells throughout the body

Mapping drug binding in individual cells throughou...

33

AI and biomarker combination to detect lung infections

AI and biomarker combination to detect lung infect...

33

AI to detect early ALS gene expression from a blood sample

AI to detect early ALS gene expression from a bloo...

60

AI-empowered dual-action PROTAC targeting PKMYT1

AI-empowered dual-action PROTAC targeting PKMYT1

102

AI-based software maps proteins and lipids within cells

AI-based software maps proteins and lipids within ...

80

Kinase inhibitor drugs found to trigger protein degradation

Kinase inhibitor drugs found to trigger protein de...

94

AI model to detect skin cancer

AI model to detect skin cancer

74

AI Uncovers Genetic Architecture of the Human Corpus Callosum

AI Uncovers Genetic Architecture of the Human Corp...

117

AI can speed antibody design

AI can speed antibody design

116

AI generative models reveal the cortical representation of dancing

AI generative models reveal the cortical represent...

72

AI based biophysical models of neural dynamics

AI based biophysical models of neural dynamics

85

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

19

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

89

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

70

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

93

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

127

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

99

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

132

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

160

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

129

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

312

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

287

Programmable gene insertion in human cells using a new gene editor

Programmable gene insertion in human cells using a...

390

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

New lipid nanoparticle platform delivers mRNA to t...

525

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

32

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

147

How cell walls guide stem cells

How cell walls guide stem cells

29

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

54

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

47

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

61

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

42

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

29

Rejuvenating aged haematopoietic stem cells by targeting RhoA

Rejuvenating aged haematopoietic stem cells by tar...

73

Reversing aging in blood stem cells by targeting lysosomal dysfunction

Reversing aging in blood stem cells by targeting l...

164

Type 1 diabetes cured in mice with gentle blood stem-cell and pancreatic islet transplant

Type 1 diabetes cured in mice with gentle blood st...

52

A novel mechanism regulating bone growth

A novel mechanism regulating bone growth

75

Human stomach cells tweaked to make insulin to treat diabetes

Human stomach cells tweaked to make insulin to tre...

71

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

33

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

19

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

64

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

43

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

48

Gene linked with risk of delirium

Gene linked with risk of delirium

45

Rare human diseases from alternative start codons

Rare human diseases from alternative start codons

81

Neurodegenerative mechanisms in SETBP1 variants

Neurodegenerative mechanisms in SETBP1 variants

70

Regulating the inheritance of mitochondrial DNA mutations

Regulating the inheritance of mitochondrial DNA mu...

95

A genome-to-proteome map

A genome-to-proteome map

110

Why naked mole-rats live longer

Why naked mole-rats live longer

75

Gene therapy for alpha thalassemia major

Gene therapy for alpha thalassemia major

119

AI and lab tests to predict genetic disease risk

AI and lab tests to predict genetic disease risk

140

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

42

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

47

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

93

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

380

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

402

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

374

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

390

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

270

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

357

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

402

Role of ECM in brain memory

Role of ECM in brain memory

357

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

374

Supramolecular anticoagulants with on-demand reversibility

Supramolecular anticoagulants with on-demand rever...

374

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

43

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

34

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

59

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

73

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

55

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

90

Genetic variation impact scores for earlier heart disease detection

Genetic variation impact scores for earlier heart ...

63

A key gene behind heart defects in Down syndrome

A key gene behind heart defects in Down syndrome

76

Diabetes changes the shape of our hearts

Diabetes changes the shape of our hearts

111

High-salt diet inflames the brain and raises blood pressure

High-salt diet inflames the brain and raises blood...

184

Platelets sequester extracellular DNA, capturing tumor-derived and free fetal DNA

Platelets sequester extracellular DNA, capturing t...

264

Role of a protein tyrosine phosphatase 1B (PTP1B) in heart disease

Role of a protein tyrosine phosphatase 1B (PTP1B) ...

328

Gut bacteria derived molecule promotes atherosclerosis

Gut bacteria derived molecule promotes atheroscler...

568

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

53

How reproductive organs form

How reproductive organs form

38

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

69

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

58

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

96

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

148

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

106

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

68

Protein interaction is crucial for mouse sperm motility and male fertility

Protein interaction is crucial for mouse sperm mot...

81

How a protein regulates DNA and affects male fertility

How a protein regulates DNA and affects male ferti...

88

Functional eggs from human skin cells

Functional eggs from human skin cells

82

Sperm microRNAs regulate paternal transmission of exercise capacity

Sperm microRNAs regulate paternal transmission of ...

89

How sperm achieves energy demands for fertilization

How sperm achieves energy demands for fertilization

109

Cas12a3 cleaves tRNA tails!

Cas12a3 cleaves tRNA tails!

21

Repairing damaged lysosomal membrane

Repairing damaged lysosomal membrane

55

Regulating protein production

Regulating protein production

43

How cells eliminate inefficient ribosomes

How cells eliminate inefficient ribosomes

13

A non-coding gene controls cell size

A non-coding gene controls cell size

21

How proteins move during chemical reactions

How proteins move during chemical reactions

87

A molecular gatekeeper that controls protein synthesis

A molecular gatekeeper that controls protein synth...

68

Cleaving mechanically stressed DNA

Cleaving mechanically stressed DNA

48

Intermediate Src-kinase state that accounts for vital biological function

Intermediate Src-kinase state that accounts for vi...

48

Human DNA replication timing and initiation sites unraveled!

Human DNA replication timing and initiation sites ...

85

Biomolecular condensation precedes stress granule formation

Biomolecular condensation precedes stress granule ...

57

Membrane protein network helps transporter protein regulate cell signaling

Membrane protein network helps transporter protein...

53

Allosteric binding site for anthraquinones at the human P2X4 receptor

Allosteric binding site for anthraquinones at the ...

57

New treatment for drug-resistant fungal infections

New treatment for drug-resistant fungal infections

1

Microbes in breast milk help populate infant gut microbiomes

Microbes in breast milk help populate infant gut m...

15

Virus-drug structure, interaction in real time

Virus-drug structure, interaction in real time

35

A high-protein diet can defeat cholera infection

A high-protein diet can defeat cholera infection

47

Small RNA coded by phage controls infection

Small RNA coded by phage controls infection

48

Could your genes influence the gut microbiome of others?

Could your genes influence the gut microbiome of o...

41

How bacteria resist hostile attacks

How bacteria resist hostile attacks

54

Microbial communities in lungs linked to pneumonia recovery

Microbial communities in lungs linked to pneumonia...

42

Protection against gut infections by Klebsiella strain

Protection against gut infections by Klebsiella st...

47

How circadian rhythms help boost infection recovery

How circadian rhythms help boost infection recovery

90

Shingles vaccine may prevent, slow dementia

Shingles vaccine may prevent, slow dementia

42

Medications change our gut microbiome in predictable ways

Medications change our gut microbiome in predictab...

77

Blood-based immunological signatures for extrapulmonary tuberculosis

Blood-based immunological signatures for extrapulm...

45

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

23

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

105

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

95

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

92

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

105

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

178

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

248

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

278

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

293

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

267

New stem cell model sheds light on human amniotic sac development

New stem cell model sheds light on human amniotic ...

286

MicroRNAs guide the development of Purkinje cells

MicroRNAs guide the development of Purkinje cells

404

Ancient viral DNA shapes early embryo development

Ancient viral DNA shapes early embryo development

353

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

60

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

146

How cucumbers got longer?

How cucumbers got longer?

120

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

66

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

82

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

75

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

146

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

354

How plants sense heat during the day

How plants sense heat during the day

313

Mechanism of auxin influx in plants

Mechanism of auxin influx in plants

281

Plant-based protein is linked to a longer life

Plant-based protein is linked to a longer life

334

Epigenetic marker is essential for Marchantia sperm function

Epigenetic marker is essential for Marchantia sper...

331

Anti-bacterial role of plant metabolite

Anti-bacterial role of plant metabolite

360

Mitochondrial RNA cytosolic leakage drives the SASP

Mitochondrial RNA cytosolic leakage drives the SASP

86

Human T-cell receptor–CD3 complex structure unraveled!

Human T-cell receptor–CD3 complex structure unrave...

55

Key lung immune cells can intensify allergic reactions

Key lung immune cells can intensify allergic react...

207

A new vulnerability of asthma immune cells discovered

A new vulnerability of asthma immune cells discovered

74

Why the 'gut brain' plays a central role for allergies

Why the 'gut brain' plays a central role for aller...

79

How the gut builds long-lasting immunity after viral infections

How the gut builds long-lasting immunity after vir...

60

Mitochondrial ABHD11, a drug target in T-cell-mediated inflammation

Mitochondrial ABHD11, a drug target in T-cell-medi...

100

Oxygen deprivation drives dysfunctional neutrophil immunity

Oxygen deprivation drives dysfunctional neutrophil...

94

Psoriasis-linked gene mutation also impacts gut health

Psoriasis-linked gene mutation also impacts gut he...

89

‘Unconventional’ immune cells to tackle inflammation in the gut

‘Unconventional’ immune cells to tackle inflammati...

98

Predicting if multiple sclerosis medication will be effective for patients

Predicting if multiple sclerosis medication will b...

106

‘Creeping fat’ can worsen Crohn’s disease

‘Creeping fat’ can worsen Crohn’s disease

103

Healthy telomeres key for cancer-fighting T cells

Healthy telomeres key for cancer-fighting T cells

146

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

60

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

347

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

239

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

702

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

326

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

309

Printed skin to replace animal testing

Printed skin to replace animal testing

323

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

302

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

316

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

337

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

343

Capsules with biodegradable radio frequency antennas for assessing medication adherence

Capsules with biodegradable radio frequency antenn...

27

Redox and pH changes shuts down AQP3 channel

Redox and pH changes shuts down AQP3 channel

54

Mapping the human genome in 4D

Mapping the human genome in 4D

80

Using a microfluidic device to monitor glioblastoma treatment outcomes

Using a microfluidic device to monitor glioblastom...

36

Enzyme catalysis using thiol switching!

Enzyme catalysis using thiol switching!

42

Plant hormone based system for complete degradation of a specific target protein in vivo

Plant hormone based system for complete degradatio...

45

Brain imaging using bioluminescence

Brain imaging using bioluminescence

40

High-resolution brain mapping using X-ray ptychography

High-resolution brain mapping using X-ray ptychogr...

45

How PANX1 permeates different molecules?

How PANX1 permeates different molecules?

37

Structural mechanism behind anti-epilepsy therapies revealed!

Structural mechanism behind anti-epilepsy therapie...

64

First detailed look inside droplet-like structures of compacted DNA

First detailed look inside droplet-like structures...

57

The kinase activity of ZAK at the collided ribosome interface

The kinase activity of ZAK at the collided ribosom...

50

Mapping the molecular blueprint of blood’s secret messengers

Mapping the molecular blueprint of blood’s secret ...

183

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

85

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

286

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

268

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

282

How the brain regulates emotions

How the brain regulates emotions

364

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

361

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

348

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

396

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

358

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

370

Link between dietary choices and brain health

Link between dietary choices and brain health

343

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

279

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

412

Research

APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition

APOE4 to APOE2 allelic switching in mice improves ...

2

Mapping clinical CAR-T cells: insights from scRNA-seq

Mapping clinical CAR-T cells: insights from scRNA-seq

13

Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Circadian PERIOD proteins regulate TC-DSB repair t...

10

Coming of age: mRNA vaccines for orthoflaviviruses

Coming of age: mRNA vaccines for orthoflaviviruses

10

Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

Tumor-produced ammonia is metabolized by regulator...

23

Deep learning guided design of protease substrates

Deep learning guided design of protease substrates

13

Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother’s milk

Assembly of the infant gut microbiome and resistom...

11

RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity

RNA-triggered Cas12a3 cleaves tRNA tails to execut...

13

Reconstructing the human brain’s wiring diagram from axons up

Reconstructing the human brain’s wiring diagram fr...

575

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis

Cystathionine γ-lyase is a major regulator of cogn...

13

A multimodal vision knowledge graph of cardiovascular disease

A multimodal vision knowledge graph of cardiovascu...

27

Lack of caspase 8 directs neuronal progenitor-like reprogramming and small cell lung cancer progression

Lack of caspase 8 directs neuronal progenitor-like...

25

Bioresorbable RFID capsule for assessing medication adherence

Bioresorbable RFID capsule for assessing medicatio...

14

APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition

APOE4 to APOE2 allelic switching in mice improves ...

2

Mapping clinical CAR-T cells: insights from scRNA-seq

Mapping clinical CAR-T cells: insights from scRNA-seq

13

Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Circadian PERIOD proteins regulate TC-DSB repair t...

10

Coming of age: mRNA vaccines for orthoflaviviruses

Coming of age: mRNA vaccines for orthoflaviviruses

10

Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

Tumor-produced ammonia is metabolized by regulator...

23

Deep learning guided design of protease substrates

Deep learning guided design of protease substrates

13

Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother’s milk

Assembly of the infant gut microbiome and resistom...

11

RNA-triggered Cas12a3 cleaves tRNA tails to execute bacterial immunity

RNA-triggered Cas12a3 cleaves tRNA tails to execut...

13

Reconstructing the human brain’s wiring diagram from axons up

Reconstructing the human brain’s wiring diagram fr...

575

Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis

Cystathionine γ-lyase is a major regulator of cogn...

13

A multimodal vision knowledge graph of cardiovascular disease

A multimodal vision knowledge graph of cardiovascu...

27

Lack of caspase 8 directs neuronal progenitor-like reprogramming and small cell lung cancer progression

Lack of caspase 8 directs neuronal progenitor-like...

25

Bioresorbable RFID capsule for assessing medication adherence

Bioresorbable RFID capsule for assessing medicatio...

14

HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics

HT SpaceM: A high-throughput and reproducible meth...

23

Chimeric brain models to study human glial-neuronal and macroglial-microglial interactions

Chimeric brain models to study human glial-neurona...

37

Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Mapping cellular targets of covalent cancer drugs ...

58

Dynamic release of extracellular particles after opening of the blood-brain barrier predicts glioblastoma susceptibility to paclitaxel

Dynamic release of extracellular particles after o...

50

Activation of enzymatic catalysis via nucleic acid hybridization affords synergistic coupling of specificity, potency, and signal amplification

Activation of enzymatic catalysis via nucleic acid...

48

Spatially resolved microRNA expression in tissues: technologies, challenges, and opportunities

Spatially resolved microRNA expression in tissues:...

53

CaBLAM: a high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

CaBLAM: a high-contrast bioluminescent Ca2+ indica...

45

Nondestructive X-ray tomography of brain tissue ultrastructure

Nondestructive X-ray tomography of brain tissue ul...

38

Integrating axis quantitative trait loci looks beyond cell types and offers insights into brain-related traits

Integrating axis quantitative trait loci looks bey...

67

C-COMPASS: a user-friendly neural network tool profiles cell compartments at protein and lipid levels

C-COMPASS: a user-friendly neural network tool pro...

57

A signature-protein-based approach for accurate and efficient profiling of the human gut virome

A signature-protein-based approach for accurate an...

42

Ultrastructural membrane dynamics of mouse and human cortical synapses

Ultrastructural membrane dynamics of mouse and hum...

43

BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants

BRAIN-MAGNET: A functional genomics atlas for inte...

48

MITOCHONDRIAL DISEASES

MITOCHONDRIAL DISEASES

133

NEURO- MUSCULAR JUNCTION

NEURO- MUSCULAR JUNCTION

87

Caffeine

Caffeine

107

Diabetic Neuropathy

Diabetic Neuropathy

81

Neural Transmission

Neural Transmission

84

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

Cancer: Proto-oncogenes, Oncogenes and Anti-oncogenes

92

Cell Cycle and Apoptosis

Cell Cycle and Apoptosis

295

Potassium Channels

Potassium Channels

146

Calcium channels physiology and Therapeutics uses

Calcium channels physiology and Therapeutics uses

189

Cell Signaling and Communication between Cells

Cell Signaling and Communication between Cells

436

Humoral Immunity

Humoral Immunity

116

Cell Mediated Immunity

Cell Mediated Immunity

289

Telomere

121

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

61678

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1124

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1042

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

3073

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

351

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

346

HEAD AND NECK CANCER

HEAD AND NECK CANCER

366

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

212

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

335

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

383

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

322

Gestational diabetes therapeutics

Gestational diabetes therapeutics

318

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

338

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

514

Different types of Alzheimer's disease

Different types of Alzheimer's disease

412

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

375

Alzheimer’s therapeutics

Alzheimer’s therapeutics

373

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

366

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

395

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

335

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

359

APOE in Alzheimer’s

APOE in Alzheimer’s

422

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

490

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

514

Different types of Alzheimer's disease

Different types of Alzheimer's disease

412

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

375

Alzheimer’s therapeutics

Alzheimer’s therapeutics

373

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

366

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

395

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

335

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

359

APOE in Alzheimer’s

APOE in Alzheimer’s

422

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

490

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

347

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

384

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

323

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

322

Gestational diabetes therapeutics

Gestational diabetes therapeutics

318

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

338