Index - Sciencemission

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

Science Hangouts

Dimerization and activation of receptor tyrosine kinases: insights from quantitative fluorescence studies

2991

Spread of pathology in neurodegenerative diseases: mechanisms and implications

Science Hangouts

Spread of pathology in neurodegenerative diseases: mechanisms and implications

6

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

Science Hangouts

Discovery of GTP-Energy Sensor that Regulates Metabolism and Tumorigenesis

8

Science News Highlights

What Is Ovarian Cancer?

News highlights

What Is Ovarian Cancer?

5

Unique gene expression regulatory elements in human brain

News highlights

Unique gene expression regulatory elements in human brain

7

How pancreatic cancer survives ferroptosis?

News highlights

How pancreatic cancer survives ferroptosis?

12

News

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

15

Spino-brain–spinal cord circuit that drives chronic pain identified!

Spino-brain–spinal cord circuit that drives chroni...

30

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

21

Tau mutation drives autophagy-lysosome dysfunction

Tau mutation drives autophagy-lysosome dysfunction

42

Targeting cell surface protein uPAR with car t cell therapy to treat solid tumors and surroundings

Targeting cell surface protein uPAR with car t ce...

36

New optogenetic strategies to control neural pathways

New optogenetic strategies to control neural pathways

30

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

37

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

30

What keeps vision cells alive?

What keeps vision cells alive?

36

RNA-guided CRISPR system activates gene expression

RNA-guided CRISPR system activates gene expression

55

How inflammation may prime the gut for cancer

How inflammation may prime the gut for cancer

38

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

32

Anticancer antibodies can cause autoimmune brain disease

Anticancer antibodies can cause autoimmune brain d...

51

Spino-brain–spinal cord circuit that drives chronic pain identified!

Spino-brain–spinal cord circuit that drives chroni...

30

Tau mutation drives autophagy-lysosome dysfunction

Tau mutation drives autophagy-lysosome dysfunction

42

New optogenetic strategies to control neural pathways

New optogenetic strategies to control neural pathways

30

Anticancer antibodies can cause autoimmune brain disease

Anticancer antibodies can cause autoimmune brain d...

51

How aging changes the brains of mice similar to people

How aging changes the brains of mice similar to pe...

48

Molecular signatures of neurodegeneration using PanNDA

Molecular signatures of neurodegeneration using Pa...

51

Human psychological resilience signatures in acute stress

Human psychological resilience signatures in acute...

145

Nasal swab test spots early Alzheimer’s signals

Nasal swab test spots early Alzheimer’s signals

67

The microtubule nexus linking amyloid beta and tau

The microtubule nexus linking amyloid beta and tau

46

Mitochondrial role in microcephaly

Mitochondrial role in microcephaly

54

The brain mechanisms underlying working memory

The brain mechanisms underlying working memory

65

Three anesthesia drugs all have similar neural destabilization dynamics

Three anesthesia drugs all have similar neural des...

46

Hyperinnervation causes scar at the wounded skin

Hyperinnervation causes scar at the wounded skin

50

Targeting cell surface protein uPAR with car t cell therapy to treat solid tumors and surroundings

Targeting cell surface protein uPAR with car t ce...

36

How inflammation may prime the gut for cancer

How inflammation may prime the gut for cancer

38

Restoring mitochondrial function in dendritic cells to treat cancer

Restoring mitochondrial function in dendritic cell...

62

An unexpected food source for tumors

An unexpected food source for tumors

61

Energy crisis drives T cells to exhaustion in tumors

Energy crisis drives T cells to exhaustion in tumors

79

Thymic health and cancer!

Thymic health and cancer!

49

Catch-bond engineering “turbocharge” T cells to attack prostate cancer

Catch-bond engineering “turbocharge” T cells to at...

53

How ageing promotes metastasis

How ageing promotes metastasis

63

Combination therapy to treat glioblastoma

Combination therapy to treat glioblastoma

74

How vitamin B2 could play a role in cancer therapies

How vitamin B2 could play a role in cancer therapies

77

Src kinase on the cell surface in cancer

Src kinase on the cell surface in cancer

85

Ketone supplementation improves immunotherapy

Ketone supplementation improves immunotherapy

80

Providing T cells with a sugar source to fight solid tumors

Providing T cells with a sugar source to fight sol...

85

Selectively eliminating old, damaged fat cells

Selectively eliminating old, damaged fat cells

21

How brown adipose tissue remodels neurovasulature during thermogenesis

How brown adipose tissue remodels neurovasulature ...

43

New genetic risk score to predict diabetes, obesity and metabolic disorders

New genetic risk score to predict diabetes, obesit...

52

Iron deficiency blocks the growth of young pancreatic cells

Iron deficiency blocks the growth of young pancrea...

69

Keto diet may restore exercise benefits in people with high blood sugar

Keto diet may restore exercise benefits in people ...

162

Genetic link between T2D and high blood pressure uncovered

Genetic link between T2D and high blood pressure u...

75

Human islet cell electrical maturation

Human islet cell electrical maturation

76

Red blood cells soak up sugar at high altitude, protecting against diabetes

Red blood cells soak up sugar at high altitude, pr...

109

Blood-flow restriction training for type 2 diabetes

Blood-flow restriction training for type 2 diabetes

106

Signature in blood to better predict type 2 diabetes risk

Signature in blood to better predict type 2 diabet...

123

Two days of oatmeal reduce cholesterol level

Two days of oatmeal reduce cholesterol level

95

How weight loss benefits the health of your fat tissue

How weight loss benefits the health of your fat ti...

121

Exposure to natural light improves metabolic health

Exposure to natural light improves metabolic health

152

Whole mouse spatial transcriptomics

Whole mouse spatial transcriptomics

37

Gene signature predicting lung cancer recurrence

Gene signature predicting lung cancer recurrence

50

Bio-bank data analysis links genetics to disease risk and treatment response

Bio-bank data analysis links genetics to disease r...

50

Computational model measures telomere shortening from routine biopsies

Computational model measures telomere shortening f...

35

AI tool to predict heart diseases 15 years in advance

AI tool to predict heart diseases 15 years in advance

50

Artificial intelligence decodes tissue characteristics of type 2 diabetes

Artificial intelligence decodes tissue characteris...

61

Rapid Evolution of Complex Multi-mutant Proteins

Rapid Evolution of Complex Multi-mutant Proteins

89

Brain mechanism behind ‘flashes of intuition’

Brain mechanism behind ‘flashes of intuition’

96

AI to retrace the gene regulation evolution in human cerebellum

AI to retrace the gene regulation evolution in hum...

77

Measuring metabolic flux in brain cancer patients with AI based digital twin

Measuring metabolic flux in brain cancer patients ...

116

AI to predict the risk of cancer metastases

AI to predict the risk of cancer metastases

134

Gene therapy for chronic pain?

Gene therapy for chronic pain?

104

AI-driven tool for discovery of heart disease drugs

AI-driven tool for discovery of heart disease drugs

110

Nanoparticles hijack skull immune cells to bypass the blood-brain barrier for brain drug delivery

Nanoparticles hijack skull immune cells to bypass ...

104

Revealing the cell’s nanocourier at work!

Revealing the cell’s nanocourier at work!

72

AI-generated sensors open new paths for early cancer detection

AI-generated sensors open new paths for early canc...

97

Stabilizing synthetic gene circuits in liquid condensates

Stabilizing synthetic gene circuits in liquid cond...

153

Magnetically guided microrobots for targeted drug delivery

Magnetically guided microrobots for targeted drug ...

132

Nanobody-based recombinant antivenom

Nanobody-based recombinant antivenom

141

First artificial neurons that could directly communicate with living cells

First artificial neurons that could directly commu...

178

New insight into ion transport via angstrom-scale two-dimensional channels

New insight into ion transport via angstrom-scale ...

156

Brain probe powerfully records neural circuits during behavior

Brain probe powerfully records neural circuits dur...

183

A novel vesicle-based method to capture the native structure of membrane proteins

A novel vesicle-based method to capture the native...

204

RNA nanoparticle gene therapy to prevent premature skull fusion in newborns

RNA nanoparticle gene therapy to prevent premature...

178

Cubosome-based method for loading mRNA into exosomes

Cubosome-based method for loading mRNA into exosomes

365

Challenges to lipid nanoparticle mediated delivery of RNA to the cytosol

Challenges to lipid nanoparticle mediated delivery...

338

What keeps vision cells alive?

What keeps vision cells alive?

36

In young boys androgens promote growth of a type of brain tumor

In young boys androgens promote growth of a type o...

32

A long-term and scalable system to record from neural organoids

A long-term and scalable system to record from neu...

45

Viagra ingredient as a therapy for mitochondrial disease

Viagra ingredient as a therapy for mitochondrial d...

70

Brain organoids can be trained to solve a goal-directed task

Brain organoids can be trained to solve a goal-dir...

80

How grafted stem cells find their way in the brain

How grafted stem cells find their way in the brain

89

How exercise helps ageing muscles repair themselves

How exercise helps ageing muscles repair themselves

221

How cell walls guide stem cells

How cell walls guide stem cells

84

Patient-specific human liver model to understand disease mechanisms

Patient-specific human liver model to understand d...

113

Aquaporins in cancer stem cells targeted to prevent gastric cancer recurrence

Aquaporins in cancer stem cells targeted to preven...

105

Cellular mechanism underlying microcephaly

Cellular mechanism underlying microcephaly

114

First human heart organoid to replicate A-fib

First human heart organoid to replicate A-fib

94

Loss of laminin-α2 may lead to muscular dystrophy

Loss of laminin-α2 may lead to muscular dystrophy

91

New genetic disease causing premature aging and cognitive deficits

New genetic disease causing premature aging and co...

38

New genetic cause of rare movement disorder discovered!

New genetic cause of rare movement disorder discov...

59

FOXJ3 gene variants linked to drug-resistant focal epilepsy

FOXJ3 gene variants linked to drug-resistant focal...

59

Genetic defect that weakens esophageal lining identified!

Genetic defect that weakens esophageal lining iden...

57

How longevity is inherited across generations

How longevity is inherited across generations

119

How a chromosome reduces severity of disease in female brain

How a chromosome reduces severity of disease in fe...

71

Genetic risk factor and viral infection jointly contribute to MS

Genetic risk factor and viral infection jointly co...

109

Small RNAs in inherited blindness identified!

Small RNAs in inherited blindness identified!

88

Inheritable genetic variant offers protection against blood cancer risk and progression

Inheritable genetic variant offers protection agai...

75

Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency

Mutations in mitochondrial ferredoxin FDX2 suppres...

113

New genetic risk for severe macular degeneration revealed

New genetic risk for severe macular degeneration r...

92

Similar genetic factors underlie multiple psychiatric disorders

Similar genetic factors underlie multiple psychiat...

97

Gene linked with risk of delirium

Gene linked with risk of delirium

96

Daily multivitamin use may slow biological aging

Daily multivitamin use may slow biological aging

54

A key hormonal circuit in the kidneys

A key hormonal circuit in the kidneys

96

Remodeling of the ceramide backbone prevents kidney injury

Remodeling of the ceramide backbone prevents kidne...

105

Skin protein found to use physical tension to control tissue growth

Skin protein found to use physical tension to cont...

136

Unknown organelle inside our cells discovered!

Unknown organelle inside our cells discovered!

429

Uncovering the secret of long-lived stem cells

Uncovering the secret of long-lived stem cells

442

Microfluidic systems resembling blood vascular tissues

Microfluidic systems resembling blood vascular tis...

423

Intermittent fasting protects against liver inflammation and liver cancer

Intermittent fasting protects against liver inflam...

460

Mice with traits of Tourette disorder created

Mice with traits of Tourette disorder created

317

Autoantibody patterns in patients with rheumatoid arthritis

Autoantibody patterns in patients with rheumatoid ...

403

All individuals with two copies of the APOE4 gene develop signs of Alzheimer's

All individuals with two copies of the APOE4 gene ...

487

Role of ECM in brain memory

Role of ECM in brain memory

404

Human skeletal muscle aging atlas

Human skeletal muscle aging atlas

416

Brain-gut-heart pathway mediating cardio-protection from GLP-1 drugs

Brain-gut-heart pathway mediating cardio-protectio...

87

A single shot helps with healing after a heart attack

A single shot helps with healing after a heart attack

58

Heart-brain neuroimmune triple-node in myocardial infarction

Heart-brain neuroimmune triple-node in myocardial ...

76

Immunotherapy reduces plaque in arteries of mice

Immunotherapy reduces plaque in arteries of mice

68

Molecular mechanism underlying peripartum cardiomyopathy

Molecular mechanism underlying peripartum cardiomy...

76

A novel inflammatory function of platelets

A novel inflammatory function of platelets

89

Beige fat promotes healthy vascular function and blood pressure in mice

Beige fat promotes healthy vascular function and b...

94

Modulating energy regulator to support tumorigenesis

Modulating energy regulator to support tumorigenesis

109

Driver of cardiac injury after coronary microembolization

Driver of cardiac injury after coronary microembol...

97

Heart-brain connection via vagus nerve to keep the heart young

Heart-brain connection via vagus nerve to keep the...

135

Bacterial enzyme causing fatal heart conditions with pneumonia infections identified!

Bacterial enzyme causing fatal heart conditions wi...

132

Genetic testing trifecta predicts risk of sudden cardiac death and arrhythmia

Genetic testing trifecta predicts risk of sudden c...

113

Hypertension affects the brain much earlier than expected

Hypertension affects the brain much earlier than e...

144

Aging human breast atlas reveals cancer susceptibility

Aging human breast atlas reveals cancer susceptib...

15

Linking fertility with immune cells in the brain

Linking fertility with immune cells in the brain

58

Genomic reorganization at the transition to gametogenesis

Genomic reorganization at the transition to gameto...

62

Activating dormant eggs to restore fertility

Activating dormant eggs to restore fertility

85

sncRNAs in sperm aging

sncRNAs in sperm aging

60

Modeling human embryo implantation in vitro

Modeling human embryo implantation in vitro

122

How reproductive organs form

How reproductive organs form

101

Do hormones explain why women experience more gut pain?

Do hormones explain why women experience more gut ...

121

Sugar molecules that trigger placental formation identified!

Sugar molecules that trigger placental formation i...

109

How uterine contractions are regulated by stretch and pressure during childbirth

How uterine contractions are regulated by stretch ...

146

How the egg cell and sperm hold together so tightly

How the egg cell and sperm hold together so tightly

192

Unknown mechanism in pre-eclampsia discovered

Unknown mechanism in pre-eclampsia discovered

144

mRNA therapy restores sperm production and fertility in mice

mRNA therapy restores sperm production and fertili...

114

RNA-guided CRISPR system activates gene expression

RNA-guided CRISPR system activates gene expression

55

Role of NAC complex in protein folding

Role of NAC complex in protein folding

35

Mechanism controlling cellular stress!

Mechanism controlling cellular stress!

53

Assembly of protein degradation complex

Assembly of protein degradation complex

39

Aging alters chromatin accessibility and nuclear mechanotransduction

Aging alters chromatin accessibility and nuclear m...

78

microRNA degradation via “two-factor authentication” system

microRNA degradation via “two-factor authenticatio...

45

Preventing pulmonary arterial hypertension

Preventing pulmonary arterial hypertension

38

Cartilage breakdown regulator identified!

Cartilage breakdown regulator identified!

49

RNA binding protein detects nonoptimal codon usage to regulate mRNA stability

RNA binding protein detects nonoptimal codon usage...

65

Mechanism of blood vessel signaling bias

Mechanism of blood vessel signaling bias

60

How flexible protein regions retain their function

How flexible protein regions retain their function

66

Complex DNA structures without hydrogen bonds

Complex DNA structures without hydrogen bonds

54

Optovolution of proteins!

Optovolution of proteins!

63

Gut–brain signalling in parasite infection

Gut–brain signalling in parasite infection

54

How bacteria drive chronic kidney disease progression

How bacteria drive chronic kidney disease progression

83

Enhancing gut-brain communication reversed cognitive decline in aging mice

Enhancing gut-brain communication reversed cogniti...

84

How deadly Marburg virus enters human cells

How deadly Marburg virus enters human cells

70

Microbiota derived nicotinic acid protects colon tissue

Microbiota derived nicotinic acid protects colon t...

70

Recent pandemic viruses jumped to humans without prior adaptation

Recent pandemic viruses jumped to humans without p...

50

How bacteria suppress immune defenses in stubborn wound infections

How bacteria suppress immune defenses in stubborn ...

63

Bacteria found in mouth and gut may help protect against severe peanut allergies

Bacteria found in mouth and gut may help protect a...

48

Molecular mechanism regulating bacterial cell division discovered

Molecular mechanism regulating bacterial cell divi...

64

Infant probiotic design from global microbiome atlas

Infant probiotic design from global microbiome atlas

55

Structures of hantavirus glycoprotein tetramers

Structures of hantavirus glycoprotein tetramers

59

Key protein that stops malaria parasite growth identified!

Key protein that stops malaria parasite growth ide...

62

Microbial interactions predict gut health

Microbial interactions predict gut health

63

ZR fusion protein sways normal brain cell development toward cancer growth

ZR fusion protein sways normal brain cell developm...

30

A developmental atlas for genes and cells

A developmental atlas for genes and cells

59

Endogenous retroviruses promote early human zygotic development

Endogenous retroviruses promote early human zygoti...

83

Tapt1 gene is essential maintainer of protein synthesis and brain development

Tapt1 gene is essential maintainer of protein synt...

71

How the brain develops and resolves inflammation

How the brain develops and resolves inflammation

152

New lab-grown human embryo model produces blood cells

New lab-grown human embryo model produces blood cells

138

Fathers shape embryonic development through molecular ‘signatures’

Fathers shape embryonic development through molecu...

143

Controlling cilia formation in mammalian embryos

Controlling cilia formation in mammalian embryos

162

Neurodevelopmental disorders from loss of Polβ in developing neurons

Neurodevelopmental disorders from loss of Polβ in ...

240

Epigenetic regulation of neural stem cell aging

Epigenetic regulation of neural stem cell aging

292

A molecular mechanism affecting ciliopathies uncovered!

A molecular mechanism affecting ciliopathies uncov...

329

Novel mechanism for regulating ribosome biogenesis during brain development

Novel mechanism for regulating ribosome biogenesis...

344

Barcoding reveals early blueprints of our cellular origins

Barcoding reveals early blueprints of our cellular...

315

Novel Octameric Resistosome and Immune Mechanism in Wheat

Novel Octameric Resistosome and Immune Mechanism i...

45

Cell death's 'beautiful' rings!

Cell death's 'beautiful' rings!

61

An “electrical” circadian clock balances growth between shoots and roots

An “electrical” circadian clock balances growth be...

47

Rice gene controlling plant growth in response to nitrogen identified!

Rice gene controlling plant growth in response to ...

54

Extra iron helps stressed out wheat grow up big and strong

Extra iron helps stressed out wheat grow up big an...

119

Crop-killing pathogen found to disable plant ‘alarm system’

Crop-killing pathogen found to disable plant ‘alar...

206

How cucumbers got longer?

How cucumbers got longer?

169

Tripling wheat production gene discovered!

Tripling wheat production gene discovered!

120

SALICYLIC ACID SENSOR1 to monitor hormone levels during pathogen infection

SALICYLIC ACID SENSOR1 to monitor hormone levels d...

128

Hidden plant–microbe strategy that boosts crop growth under nutrient stress

Hidden plant–microbe strategy that boosts crop gro...

123

Role of glutamine in plant root microbial colonization

Role of glutamine in plant root microbial coloniza...

193

Potato evolved from tomato 9 million years ago

Potato evolved from tomato 9 million years ago

397

How plants sense heat during the day

How plants sense heat during the day

354

Long-term inflammatory memory driver identified!

Long-term inflammatory memory driver identified!

56

Lung fibroblasts orchestrate inflammaging in old people

Lung fibroblasts orchestrate inflammaging in old ...

46

Vitamin D regulation of immune- gut microbiome interactions in IBD

Vitamin D regulation of immune- gut microbiome int...

55

Immune cells regulate eye pressure linked to glaucoma

Immune cells regulate eye pressure linked to glaucoma

52

How the fats we eat shape our ability to fight disease

How the fats we eat shape our ability to fight dis...

63

How immune cells extract nuclear DNA from dying cells

How immune cells extract nuclear DNA from dying cells

90

How the immune system recognizes viral RNA

How the immune system recognizes viral RNA

68

How dietary restriction rewires immunity to protect against infection

How dietary restriction rewires immunity to protec...

42

How chronic inflammation rewires macrophages

How chronic inflammation rewires macrophages

125

How a common immunosuppressive drug “ATG” injures liver blood vessels

How a common immunosuppressive drug “ATG” injures ...

58

DNA-protein crosslinks promote inflammation-linked premature aging and embryonic lethality

DNA-protein crosslinks promote inflammation-linked...

62

Enzyme required for transition from monocyte to tissue-resident macrophage identified!

Enzyme required for transition from monocyte to ti...

86

Fat surrounding the colon interacts with the immune system

Fat surrounding the colon interacts with the immun...

158

Optical neural control by blood-catalyzed polymers

Optical neural control by blood-catalyzed polymers

29

Cell ratio control using synthetic circuits

Cell ratio control using synthetic circuits

34

Cellular mechano-sensation linked to gene enhancers!

Cellular mechano-sensation linked to gene enhancers!

115

Implant treats Type 1 diabetes by oxygenating insulin-producing cells

Implant treats Type 1 diabetes by oxygenating insu...

396

Protecting the biomolecules with simple peptides

Protecting the biomolecules with simple peptides

291

Trapping gut microbiota produced molecule to improve blood sugar levels

Trapping gut microbiota produced molecule to impro...

752

Converting urine into high-value bio-implant material

Converting urine into high-value bio-implant material

374

MetaFlowTrain to study ‘metabolic dialogue’ between microorganisms

MetaFlowTrain to study ‘metabolic dialogue’ betwee...

372

Printed skin to replace animal testing

Printed skin to replace animal testing

371

White blood cells use brute force to dislodge bacteria

White blood cells use brute force to dislodge bact...

345

Laser-made, ultra-thin material for tracking of healing wounds

Laser-made, ultra-thin material for tracking of he...

362

Synthetic phosphorylation signaling networks in human cells

Synthetic phosphorylation signaling networks in hu...

392

Axon-mimicking materials for signal transmission

Axon-mimicking materials for signal transmission

391

How the body senses cold

How the body senses cold

61

New computational biology for genome sequencing analysis

New computational biology for genome sequencing an...

54

Ultrasound-based technology to deliver large therapeutics into cancer cells

Ultrasound-based technology to deliver large thera...

72

Glycoprotein heterodimers on nanoparticles for hepatitis C virus vaccine design

Glycoprotein heterodimers on nanoparticles for hep...

55

Assay to analyze regulatory function and epigenomic modifications simultaneously

Assay to analyze regulatory function and epigenomi...

61

Peptide ligase–mediated display

Peptide ligase–mediated display

48

Na pump relies on dynamic conformational changes for its action

Na pump relies on dynamic conformational changes f...

63

How bacteria bind to different types of cells

How bacteria bind to different types of cells

27

Smart, wearable bioelectronic stress assessment device

Smart, wearable bioelectronic stress assessment de...

74

New method predicts asthma attacks up to five years in advance

New method predicts asthma attacks up to five year...

58

Three-dimensional ultrafast vascular ultrasound to precisely assess steatotic liver disease

Three-dimensional ultrafast vascular ultrasound to...

75

Implanted skin sensor for long-term biomarker monitoring

Implanted skin sensor for long-term biomarker moni...

75

‘Revoice’ device gives stroke patients their voice back

‘Revoice’ device gives stroke patients their voice...

88

Societal inequality linked to structural brain changes in children

Societal inequality linked to structural brain cha...

135

How gut bacteria change after exposure to pesticides

How gut bacteria change after exposure to pesticides

321

Fire smoke exposure impacts Immune system

Fire smoke exposure impacts Immune system

323

Global warming linked to dangerous sleep apnea

Global warming linked to dangerous sleep apnea

330

How the brain regulates emotions

How the brain regulates emotions

414

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIVE CEREBELLAR LEARNING

CLIMBING FIBRES AS TEACHING SIGNALS FOR ASSOCIATIV...

406

More influence of environment than genetics in metacognitive abilities

More influence of environment than genetics in met...

391

Vitamin D regulates microbiome-dependent cancer immunity

Vitamin D regulates microbiome-dependent cancer im...

436

Vision plays a key role in sculpting brain development

Vision plays a key role in sculpting brain develop...

403

Without genetic mutations tumors are formed!

Without genetic mutations tumors are formed!

413

Link between dietary choices and brain health

Link between dietary choices and brain health

381

How the brain's arousal center also helps control visual attention

How the brain's arousal center also helps control ...

338

Sub-cortical connections critical to human consciousness identified!

Sub-cortical connections critical to human conscio...

465

Research

What Is Ovarian Cancer?

What Is Ovarian Cancer?

11

Characterization of functional human-specific regulatory elements in prefrontal cortical cells

Characterization of functional human-specific regu...

27

Single-cell spatial atlas of the aging human breast

Single-cell spatial atlas of the aging human breast

12

Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain

Deconstruction of a spino-brain–spinal cord circui...

570

Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice

Homoharringtonine exhibits senotherapeutic activi...

17

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia

A pathogenic Tau mutation drives autophagy-lysosom...

20

A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

A convergent uPAR-positive tumor ecosystem creates...

20

The HIF-2 transcription factor mediates resistance to ferroptosis in pancreatic cancer

The HIF-2 transcription factor mediates resistance...

40

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

18

Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity

Astrocyte States in Brain Aging and Neurodegenerat...

35

$Could venom-derived therapeutics resolve treatment resistance in refractory EAC?$

Could venom-derived therapeutics resolve treatment...

21

Whole-body molecular and cellular mapping of the laboratory mouse

Whole-body molecular and cellular mapping of the l...

21

Repair condensates and lipid domains in lysosome integrity

Repair condensates and lipid domains in lysosome i...

45

What Is Ovarian Cancer?

What Is Ovarian Cancer?

11

Characterization of functional human-specific regulatory elements in prefrontal cortical cells

Characterization of functional human-specific regu...

27

Single-cell spatial atlas of the aging human breast

Single-cell spatial atlas of the aging human breast

12

Deconstruction of a spino-brain–spinal cord circuit that drives chronic pain

Deconstruction of a spino-brain–spinal cord circui...

570

Homoharringtonine exhibits senotherapeutic activity that mitigates diet- and age-associated obesity and insulin resistance and extends lifespan in mice

Homoharringtonine exhibits senotherapeutic activi...

17

A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia

A pathogenic Tau mutation drives autophagy-lysosom...

20

A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

A convergent uPAR-positive tumor ecosystem creates...

20

The HIF-2 transcription factor mediates resistance to ferroptosis in pancreatic cancer

The HIF-2 transcription factor mediates resistance...

40

Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and Reactivity

Astrocyte States in Brain Aging and Neurodegenerat...

35

$Could venom-derived therapeutics resolve treatment resistance in refractory EAC?$

Could venom-derived therapeutics resolve treatment...

21

Repair condensates and lipid domains in lysosome integrity

Repair condensates and lipid domains in lysosome i...

45

Dominant clones leverage developmental epigenomic states to drive ependymoma

Dominant clones leverage developmental epigenomic ...

21

T-loop dynamics: telomere structure shapes cell fate decisions

T-loop dynamics: telomere structure shapes cell fa...

42

Projection-specific intersectional optogenetics for precise excitation and inhibition in the marmoset brain

Projection-specific intersectional optogenetics fo...

18

Whole-body molecular and cellular mapping of the laboratory mouse

Whole-body molecular and cellular mapping of the l...

21

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell lines

Electrophysiological development and functional pl...

33

Tissue morphology predicts telomere shortening in human tissues

Tissue morphology predicts telomere shortening in ...

35

Metapipeline-DNA: A comprehensive germline and somatic genomics Nextflow pipeline

Metapipeline-DNA: A comprehensive germline and som...

37

Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain

Genetically encoded fluorescent reporters to visua...

49

MitoTracker transfers from astrocytes to neurons independently of mitochondria

MitoTracker transfers from astrocytes to neurons i...

71

Artificial intelligence-driven whole-brain cell mapping with highly multiplexed in situ hybridization

Artificial intelligence-driven whole-brain cell ma...

75

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

Simultaneous epigenomic profiling and regulatory a...

99

Single-cell and isoform-specific translational profiling of the mouse brain

Single-cell and isoform-specific translational pro...

80

Medaka: a novel model for analyzing genome– environment interactions

Medaka: a novel model for analyzing genome– enviro...

4622

Development of human induced pluripotent stem cell-derived ovarian support cells as a clinical-grade product for in vitro fertilization

Development of human induced pluripotent stem cell...

70

Challenges and opportunities in adapting high-throughput functional assays for in vivo neuroscience

Challenges and opportunities in adapting high-thro...

79

THALASSEMIA

THALASSEMIA

86

BASIC PRINCIPLES OF IMMUNOTHERAPY

BASIC PRINCIPLES OF IMMUNOTHERAPY

97

NMDA RECEPTORS

NMDA RECEPTORS

139

Neural Development

Neural Development

109

Transcription Factors

Transcription Factors

158

Interferons

86

RABIES

64

ANEMIA

56

Ubiquitin-mediated proteolysis

Ubiquitin-mediated proteolysis

73

Migraine

53

Dementia

99

Trisomy

71

Cystic Fibrosis

Cystic Fibrosis

80

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AGENTS AND TUMOR BIOLOGY

DEVELOPMENTAL THERAPEUTICS—MOLECULARLY TARGETED AG...

85984

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

DEVELOPMENTAL THERAPEUTICS—IMMUNOTHERAPY

1328

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

GASTROINTESTINAL CANCER—COLORECTAL AND ANAL

1193

GYNECOLOGIC CANCER

GYNECOLOGIC CANCER

4171

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

GENITOURINARY CANCER—PROSTATE, TESTICULAR, AND PENILE

407

GENITOURINARY CANCER—KIDNEY AND BLADDER

GENITOURINARY CANCER—KIDNEY AND BLADDER

393

HEAD AND NECK CANCER

HEAD AND NECK CANCER

419

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

HEALTH SERVICES RESEARCH AND QUALITY IMPROVEMENT

259

Single-molecule covalent magnetic tweezers

Single-molecule covalent magnetic tweezers

387

A chemical biology/modular antibody platform for ADP-ribosylation signaling

A chemical biology/modular antibody platform for A...

428

School Science

Disease Science

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

375

Gestational diabetes therapeutics

Gestational diabetes therapeutics

360

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

402

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

573

Different types of Alzheimer's disease

Different types of Alzheimer's disease

486

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

432

Alzheimer’s therapeutics

Alzheimer’s therapeutics

445

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

456

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

467

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

405

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

416

APOE in Alzheimer’s

APOE in Alzheimer’s

504

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

557

C9ORF72 gene in Alzheimer’s disease

C9ORF72 gene in Alzheimer’s disease

573

Different types of Alzheimer's disease

Different types of Alzheimer's disease

486

How does Alzheimer's disease progress over time?

How does Alzheimer's disease progress over time?

432

Alzheimer’s therapeutics

Alzheimer’s therapeutics

445

Genetics of Alzheimer’s disease

Genetics of Alzheimer’s disease

456

Microglia in Alzheimer’s disease

Microglia in Alzheimer’s disease

467

Neuroinflammation in Alzheimer’s disease

Neuroinflammation in Alzheimer’s disease

405

Gut microbiota and Alzheimer’s disease

Gut microbiota and Alzheimer’s disease

416

APOE in Alzheimer’s

APOE in Alzheimer’s

504

Cellular and molecular mechanisms of Alzheimer’s disease

Cellular and molecular mechanisms of Alzheimer’s d...

557

Amyloid precursor protein in Alzheimer's disease

Amyloid precursor protein in Alzheimer's disease

403

Tau in Alzheimer’s disease

Tau in Alzheimer’s disease

454

Presenilin (PSEN) in Alzheimer’s

Presenilin (PSEN) in Alzheimer’s

384

Gestational diabetes etiology and molecular mechanisms

Gestational diabetes etiology and molecular mechan...

375

Gestational diabetes therapeutics

Gestational diabetes therapeutics

360

Genetic factors in Gestational Diabetes

Genetic factors in Gestational Diabetes

402